Robert Hudson
Contact Information
Title: Professor
Office: Rm 222 ChB
Labs: 200 & 201 ChB
Phone (Office): ext 86349
E-mail: rhhudson@uwo.ca
Organic Teaching Division
Chemical Biology and Biomaterials
Synthetic and Bioorganic Chemistry of Nucleic Acids and Peptides
AWARDS
- Faculty Scholar 2010-2012
- USC Bank of Nova Scotia Alumni Award of Excellence in Undergraduate Teaching 2009-2010
- President's Occupational Health & Safety Award, 2008
- University Students' Council Teaching Honour Roll 2006-2007
- CNC-IUPAC Award, 2004
RESEARCH
Our principle research activities involve the application of organic synthesis in the field of bio-organic chemistry. We specialize in oligonucleotide analogs and our work is focused on peptide nucleic acid or PNA and nucleobase-modified DNA and RNA with special interest in fluorescent analogs.
For more information about the group please visit our research group homepage.
TEACHING
- 2213 - Organic Chemistry for Life Sciences
- 2223 - Organic Chemistry of Biological Molecules
- 2273 - Organic Chemistry I: Structure and Spectroscopy
- 3393 - Medicinal Chemistry
- 4493 - Chemistry of Biological Macromolecules
- 9520 - Advanced Nucleic Acid Chemistry
- 9553 - Mechanistic Organic Chemistry
SELECTED PUBLICATIONS
- Mojmír Suchý, Christie Ettles, James Wisner, Augusto Matarazzo, and Robert H. E. Hudson, 2016, “Unusual C- versus normal 5’-O-Dimethoxytritylation of Pyrrolocyidine Analogues”, Journal of Organic Chemistry, 81(18), 8415–8425.
- Mojmir Suchý, Alex X. Li, Mark Milne, Robert Bartha, and Robert .H.E. Hudson, 2016, “DOTMA-based amides (DOTMAMs) as a platform for the development of PARACEST MRI contrast agents”, RSC Advances, 6(67), 62647-62655.
- Xiaoxiao Wang and Robert H.E. Hudson, 2015, “A PNA Molecular Beacon Assembled by Post-Synthetic “Click” Chemistry Functionalization”, ChemBioChem, 16, 2156–2161.
- Pierangelo Gobbo, Wilson Luo, Sung Ju Cho, Xiaoxiao Wang, Mark C. Biesinger, Robert H.E. Hudson, Mark S. Workentin, 2015, "Small gold nanoparticles for interfacial Staudinger-Bertozzi ligation", Organic & Biomolecular Chemistry, 13(4), 605-4612.
- Mojmir Suchy, Robert H.E. Hudson, 2014, "Pyrimidine-Fused Heterocyclic Frameworks Based on an N4-Arylcytosine Scaffold: Synthesis, Characterization, and PNA Oligomerization of the Fluorescent Cytosine Analogue 5,6-BenzopC", Journal of Organic Chemistry, 79(8), 3336-3347.
