- A Western University study suggests that the changes in a person's genetic makeup can help with individualized treatment for schizophrenia. After a two-decade long study, Western researchers discovered that the genetic makeup of a pair of rare identical twins — one twin had schizophrenia and the other did not — was not in fact identical.
- A Western University study on identical twins is uncovering just how genetically different schizophrenia can be — a discovery that could possibly help doctors diagnose and treat the devastating mental disorder more effectively. During two decades, Western researchers studied two very rare sets of identical twins. In each pair, one twin had schizophrenia and the other did not.
- Schizophrenia is one of the world’s most devastating mental disorders and affects more than 21 million people globally. A new study of identical twins shows for the first time that schizophrenia may be caused by not one distinct but an accumulation of gene mutations, some of which are not inherited from the twins’ parents. These de novo somatic mutations occur independently in every individual as we develop, grow and age.
- Research out of Western University suggests schizophrenia can be diagnosed by studying a person’s DNA, paving the way for an individualized treatment plan. Lead researcher Dr. Shiva Singh, a professor in Western’s Faculty of Science, says his work over the past 20 years challenges a “very fundamental principle” that a person’s genome sequence doesn’t change throughout the course of a lifetime.