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Dr. Morris Karmazyn

University of Western Ontario Dept. Physiology and Pharmacology Medical Sciences Building, Rm. 252   Dr. Karmazyn's research area is cardiac hypertrophy and heart failure, and his research objective is to determine whether ginsenosides exert direct  cardiac antihypertrophic effects  and to determine the intracellular mechanisms for these effects. His lab is establishing mechanisms of action that produce antihypertropic effects of ginsenosides using rat coronary artery ligation/heart failure model and in vitro assays such as cultured cardiomyocytes including indices of hypertrophy, cell signalling, TF activation, intracellular ion regulation, etc.