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Western Bioinformatics Research Seminar
Time and date: 11:00 am - 12:00pm EST , Thursday/September 24, 2026, via zoom
Speaker Name:
Bowen Li
Title/affiliation:
Associate Professor and Canada Research Chair, Leslie Dan Faculty of Pharmacy, University of Toronto
Presentation title:
AI-Driven Design of Lipid Nanoparticles for mRNA Delivery
Learning objectives:
- Understand the design principles behind ionizable lipids used in LNP-based mRNA delivery, including combinatorial and machine-learning-guided design strategies.
- Learn how four-component reactions enable rapid, combinatorial generation of ionizable lipid libraries.
- Explore barcoded in vivo screening approaches for identifying organ- and cell-targeted LNP formulations (e.g., lung, T cells, tumor).
- See how AI-guided LNP platforms are applied to mRNA therapeutics.