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Publications
2024
  1. Tschirhart BJ, Lu X, Mokale Kognou AL, Martin CM, Slessarev M, Fraser DD, Leligdowicz A, Urquhart B, Feng Q. Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19. Front Pharmacol. 2024;14:1299613.  PDF
2023
  1. Martin CM, Slessarev M, Campbell E, Basmaji J, Ball I, Fraser DD, Leligdowicz A, Mele T, Priestap F, Tschirhart BJ, Bentall T, Lu X, Feng Q. Annexin A5 in patients with severe COVID-19 disease: a single-center, randomized, double-blind, placebo-controlled feasibility trial. Crit Care Explor. 2023;5(10):e0986.  PDF
  2. Tschirhart BJ, Lu X, Gomes J, Chandrabalan A, Bell G, Hess DA, Xing G, Ling H, Burger D, Feng Q. Annexin A5 inhibits endothelial inflammation induced by lipopolysaccharide-activated platelets and microvesicles via phosphatidylserine binding. Pharmaceuticals. 2023;16:837.  PDF
  3. Nguyen HC, Bu S, Nikfarjam S, Rasheed B, Michels DCR, Singh A, Singh S, Marszal C, McGuire JJ, Feng Q, Frisbee JC, Qadura M, Singh KK. Loss of fatty acid binding protein 3 ameliorates lipopolysaccharide-induced inflammation and endothelial dysfunction. J Biol Chem. 2023;299(3):102921.
  4. Ye F, Lu X, van Neck R, Jone DL, Feng Q. Novel circRNA-miRNA-mRNA networks regulated by maternal exercise in fetal hearts of pregestational diabetes. Life Sci. 2023;314:121308.  PDF
2022
  1. Robinson GI, Ye F, Lu X, Laviolette SR, Feng Q. Maternal delta-9-tetrahydrocannabinol exposure induces abnormalities of the developing heart in mice. Cannabis Cannabinoid Res. 2022.  PDF
  2. Blom JN, Wang X, Lu X, Kim MY, Wang G, Feng Q. Inhibition of intraflagellar transport protein-88 promotes epithelial-to-mesenchymal transition and reduces cardiac remodeling post-myocardial infarction. Eur J Pharmacol. 2022; 933:175287.  PDF
  3. Greco ER, Engineer A, Saiyin T, Lu X, Zhang M, Jones DL, Feng Q. Maternal nicotine exposure induces congenital heart defects in the offspring of mice. J Cell Mol Med. 2022; 26(11):3223-3234. Open Access  PDF
2021
  1. Mui L, Martin CM, Tschirhart BJ, Feng Q. Therapeutic potential of annexins in sepsis and COVID-19. Front Pharmacol. 2021; 12:735472. Open Access
  2. Leung C, Engineer A, Lu X, Kim MY, Feng Q. Myocardium-specific deletion of Rac1 causes ventricular noncompaction and outflow tract defects. J Cardiovsc Dev Dis. 2021; 8(3):29. Open Access  PDF
2020
  1. Moazzen H, Wu Y, Engineer A, Lu X, Aulakh S, Feng Q. NOX2 is critical to endocardial to mesenchymal transition and heart development. Oxid Med Cell Longev. 2020; 1679045:1-12. Open Access  PDF
  2. Engineer A, Lim YJ, Lu X, Kim MY, Norozi K, Feng Q. Sapropterin reduces coronary artery malformation in offspring of pregestational diabetes mice. Nitric Oxide. 2020; 94:9-18.  PDF
  3. Novello MJ, Zhu J, Zhang M, Feng Q, Stathopulos PB. Synergistic stabilization by nitrosoglutathione-induced thiol modifications in the stromal interaction molecule-2 luminal domain suppresses basal and store operated calcium entry. Sci Rep. 2020; 10:10177.  PDF
2019
  1. Engineer A, Saiyin T, Greco ER, Feng Q. Say NO to ROS: Their roles in embryonic heart development and pathogenesis of congenital heart defects in maternal diabetes. Antioxidants. 2019; 8(10), 436.   PDF
  2. Saiyin T, Engineer A, Greco ER, Kim MY, Lu X, Jones DL, Feng Q. Maternal voluntary exercise mitigates oxidative stress and incidence of congenital heart defects in pre-gestational diabetes. J Cell Mol Med. 2019; 23(8):5553-5565.   PDF
  3. Novielli-Kuntz NM, Jelen M, Barr K, DeLalio LJ, Feng Q, Isakson BE, Gros R, Laird DW. Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice. Biosci Rep. 2019 Feb 27;39(2). pii: BSR20182350.   PDF
2018
  1. Engineer A, Saiyin T, Lu X, Kucey AS, Urquhart BL, Drysdale TA, Norozi K, Feng Q. Sapropterin treatment prevents congenital heart defects induced by pregestational diabetes in mice. J Am Heart Assoc. 2018;7:e009624.   PDF
  2. Peterson JC, Chugntai M, Wisse L, Gittenberger-de Groot A, Jongbloed MRM, Feng Q, Goumans MJ, VanMunsteren C, DeRuiter M. Nos3 mutation leads to abnormal neural crest cell and second heart field lineage patterning in bicuspid aortic valve formation. Dis Model Mech. 2018;11:dmm034637.   PDF
  3. Zhu J, Lu X, Feng Q, Stathopulos PB. A charge sensing region in the stromal interaction molecule-1 luminal domain confers stabilization-mediated inhibition of SOCE in response to S-nitrosylation. J Biol Chem. 2018;293:8900-8911.   PDF
  4. Le G, Zhu J, Lu X, Sims SM, Lu WY, Stathopulos PB, Feng Q. S-Nitrosylation of STIM1 by neuronal nitric oxide synthase inhibits store-operated calcium entry. J Mol Biol. 2018;430:1773–1785.   PDF
  5. Novello MJ, Zhu J, Feng Q, Ikura M, Stathopulos PB. Structural elements of stromal interaction molecule function. Cell Calcium. 2018;73:88-94.   PDF
  6. Blom JN, Feng Q. Cardiac repair by epicardial EMT: Current targets and a potential role for the primary cilium. Pharmacol Ther. 2018;186:114-129.   PDF
  7. Zhang L, Wang X, Wu Y, Lu X, Chidiac P, Feng Q. Maternal diabetes upregulates NOX2 and enhances myocardial ischemia/reperfusion injury in adult offspring. J Cell Mol Med. 2018;22:2200-2209.   PDF
2017
  1. Zhu J, Feng Q, Stathopulos PB. The STIM-Orai Pathway: STIM-Orai Structures: Isolated and in Complex. Adv Exp Med Biol. 2017;993:15-38.   PDF
  2. Choi YJ, Zhu J, Chung S, Siddiqui N, Feng Q, Stathopulos PB. Targeting cysteine thiols for in vitro site-specific glycosylation of recombinant proteins. J Vis Exp. 2017;128, e56302.   PDF
  3. Feng AL, Xiang YY, Gui L, Kaltsidis G, Feng Q, Lu WY. Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes. Diabetologia. 2017;60:1033-1042.   PDF
  4. Lee K, Lu X, Nguyen CH, Feng Q, Chidiac P. Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice. J Mol Cell Cardiol. 2017;108:194-202.  PDF
  5. Tyml K, Swarbreck S, Pape C, Secor D, Koropatnick J, Feng Q, Veldhuizen RA, Gill SE. Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice. Crit Care. 2017;21:210.  PDF
2016
  1. Wu Y, Qin C, Lu X, Marchiori J, Feng Q. North American ginseng inhibits myocardial NOX2-ERK1/2 signaling and tumor necrosis factor-alpha expression in endotoxemia. Pharmacol Res. 2016;111:217-225.   PDF
  2. Zhang L, Lu X, Gui L, Wu Y, Sims SM, Wang G, Feng Q. Inhibition of Rac1 reduces store overload-induced calcium release and protects against ventricular arrhythmia. J Cell Mol Med. 2016;20:1513-22.   PDF
  3. Blom JN, Lu X, Arnold P, Feng Q. Myocardial infarction in neonatal mice, a model of cardiac regeneration. J Vis Exp. 2016;111:e54100.   PDF
  4. da Silveira Cavalcante L, Feng Q, Chin-Yee I, Acker J. Holovati J. Effect of liposome-treated red blood cells in an anemic rat model. J Liposome Res. 2016 Apr 8:1-8   PDF
  5. Secor D, Swarbreck S, Ellis CG, Sharpe MD, Feng Q, Tyml K. Ascorbate inhibits platelet-endothelial adhesion in an in-vitro model of sepsis via reduced endothelial surface P-selectin expression. Blood Coagul Fibrinolysis. 2017;28:28-33.   PDF
  6. Roy A, Bakroub M, Tezini GC, Liu Y, Guatimosim S, Feng Q, Faza Jr. R, Salgado HC, Prado VF, Prado MA, Gros R. Cardiac acetylcholine inhibits ventricular remodeling and dysfunction under pathological conditions. FASEB J. 2016;30:688-701.   PDF
  7. Leung C, Liu Y, Lu X, Kim M, Drysdale TA, Feng Q. Rac1 signaling is required for anterior second heart field cellular organization and cardiac outflow tract development. J Am Heart Assoc. 2016;5:e002508.   PDF
2015
  1. Pest MA, Pest CA, Bellini M, Feng Q, Beier F. Deletion of dual specificity phosphatase 1 does not predispose mice to increased spontaneous osteoarthritis. PLoS ONE. 2015;10(11):e0142822.   PDF
  2. Moazzen H, Lu X, Liu M, Feng Q. Pregestational diabetes induces fetal coronary artery malformation via reactive oxygen species signaling. Diabetes. 2015;64:1431-43.   PDF
  3. Teasell RW, Feng Q. Hypersensitivity of vascular alpha-adrenoceptor responsiveness: a possible inducer of pain in neuropathic states (Letter to Editor). Neural Regeneration Res. 2015;10:165.   PDF
2014
  1. Leung C, Lu X, Liu M, Feng Q. Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development. J Am Heart Assoc. 2014;3:e001271.   PDF
  2. Xiang FL, Liu Y, Lu X, Jones DL, Feng Q. Cardiac-specific overexpression of human stem cell factor promotes epicardial activation and arteriogenesis after myocardial infarction. Circulation Heart Failure. 2014;7:831-42.   PDF
  3. Liu Y, Lu X, Xiang FL, Poelmann RE, Gittenberger-de Groot AC, Robbins J, Feng Q. Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction. Eur Heart J. 2014;35:920-31.   PDF
  4. Moazzen H, Lu X, Ma NL, Velenosi TJ, Urquhart BL, Wisse LJ, Gittenberger-de Groot AC, Feng Q. N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes. Cardiovasc Diabetol. 2014;13:46.   PDF   This is a 'Highly Accessed' article.
  5. Arnold P, Lu X, Amirahmadi F, Brandl K, Arnold JMO, Feng Q. Recombinant human annexin A5 inhibits pro-inflammatory response and improves cardiac function and survival in mice with endotoxemia. Crit Care Med. 2014;42:e32-41.   PDF
2013
  1. Mitchell AJ, Sabondjian E, Balckwood KJ, Sykes J, Deans L, Feng Q, Stodilka RZ, Prato F, Wisenberg G. Comparison of the myocardial clearance of endothelial progenitor cells injected early vs. late into reperfused or sustained occlusion myocardial infarction. Intl J Cardiovasc Imaging. 2013; 29:497-504.   PDF
  2. Xiang FL, Lu X, Liu Y, Feng Q. Cardiomyocyte-specific overexpression of human stem cell factor protects against myocardial ischemia and reperfusion injury. Intl J Cardiol. 2013;168:3486-94.   PDF
  3. Liu Y, Lu X, Xiang FL, Lu M, Feng Q. Nitric oxide synthase-3 promotes embryonic development of atrioventricular valves. PLoS ONE. 2013;8:e77611.   PDF
2012
  1. Hu H, Xenocostas A, Chin-Yee N, Lu X, Chin-Yee I, Feng Q. Transfusion of fresh but not stored blood reduces infarct size and improves cardiac function following acute myocardial infarction in anemic rats. Crit Care Med. 2012;40:740-6.   PDF
  2. Yan Q, Feng Q, Beier F. Reduced chondrocyte proliferation, earlier cell cycle exit and increased apoptosis in neuronal nitric oxide synthase-deficient mice. Osteoarthritis Cartilage. 2012;20:144-51.   PDF
  3. Zhang T, Lu X, Arnold P, Liu Y, Baliga R, Huang H, Bauer JA, Liu YS, Feng Q. Mkp-1 inhibits myocardial tumor necrosis factor-alpha expression and improves cardiac function during endotoxemia. Cardiovasc Res. 2012;93:471-479.   PDF
  4. Zhang T, Lu X, Li J, Chidiac P, Sims SM, Feng Q. Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia. Basic Res Cardiol 2012;107(2):254.   PDF
  5. Detombe SA, Xiang FL, Dunmore-Buyze J, White JA, Feng Q, Drangova M. Rapid micro-computed tomography suggests cardiac enlargement occurs during conductance catheter measurements in mice. J Appl Physiol. 2012; 113:142-148.   PDF
  6. Liu Y, Feng Q. NOing the heart: Role of nitric oxide synthase-3 in heart development (Review). Differentiation 2012; 84:54-61.   PDF
  7. Chin-Yee I, Xenocostas A, Feng Q. Current randomized clinical trials of red cell storage duration and patient outcomes (Response to the Editor). Critical Care Med. 2012; 40:2927-2928.   PDF
2011
  1. Turner J, Xiang FL, Feng Q, Wagner GF. The renal stanniocalcin-1 gene is differentially regulated by hypertonicity and hypovolemia in the rat. Mol Cell Endocrinol. 2011; 331:150-157.   PDF
  2. Zhang T, Lu X, Beier F, Feng Q. Rac1 activation induces tumor necrosis factor-alpha expression and cardiac dysfunction in endotoxemia. J Cell Mol Med. 2011;15:1109-1121.   PDF
  3. Hammoud L, Lu X, Lei M, Feng Q. Deficiency in TIMP-3 Increases cardiac rupture and mortality post-myocardial infarction via EGFR signalling: Beneficial effects of cetuximab. Basic Res Cardiol. 2011; 106:459-471.   PDF
  4. Wu Y, Lu X, Xiang FL, Lui EMK, Feng Q. North American ginseng protects the heart from ischemia and reperfusion injury via upregulation of endothelial nitric oxide synthase. Pharmacol Res. 2011; 64:195-202.   PDF
  5. Wang G, Yan Q, Woods A, Aubrey LA, Feng Q, Beier F. iNOS/nitric oxide signaling mediates the mitogenic activity of Rac1 during endochondral bone growth. J Cell Sci 2011; 124:3405-3413.   PDF
  6. Nong Z, O'Neil C, Lei M, Gros R, Watson A, Li S, Frontini MJ, Feng Q, Pickering JG. Type I collagen cleavage is essential for effective fibrotic repair following myocardial infarction. Am J Pathol. 2011; 179:2189-2198.   PDF
  7. Feng Q, Scott J. Nitric Oxide, from its chemistry to biology and disease (Editorial). Open Nitric Oxide J. 2011; 3(Suppl 1-M1): 6-7.   PDF
  8. Burger DE, Feng Q. Protective role of nitric oxide against cardiac arrhythmia - An update (Review). Open Nitric Oxide J. 2011; 3 (Suppl 1-M6):38-47.   PDF
2010
  1. Feng B, Chen S, George B, Feng Q, Chakrabarti S. miR133a regulates cardiomyocyte hypertrophy in diabetes. Diabetes Metab Res Rev. 2010;26:40-49.   PDF
  2. Hu H, Xenocostas A, Chin-Yee I, Lu X, Feng Q. Effects of anemia and blood transfusion in acute myocardial infarction in rats. Transfusion. 2010; 50:243-251.   PDF
  3. Mitchell AJ, Sabondjian E, Sykes J, Deans L, Zhu W, Lu X, Feng Q, Prato FS, Wisenberg G. Comparison of initial cell retention and clearance kinetics following subendocardial or subepicardial injections of endothelial progenitor cells in a canine myocardial infarction model. J Nuclear Med. 2010;51(3):413-417.   PDF
  4. Yan Q, Feng Q, Beier F. Endothelial nitric oxide synthase deficiency results in reduced chondrocyte proliferation and endochondral bone growth. Arthritis & Rheumatism. 2010; 62:2013-2022.   PDF
  5. Kennedy KAM, Ostrakhovitch EA, Sandiford SDE, Dayarathna T, Xie X, Waese EYL, Chang WY, Feng Q, Skerjanc IS, Stanford WL, Li SSC. Mammalian numb interacting protein1/dual oxidase maturation factor1 directs neuronal fate in stem cells. J Biol Chem 2010;285:17974-17985.   PDF
  6. Xiang FL, Lu X, Strutt B, Hill DJ, Feng Q. NOX2 deficiency protects against streptozotocin-induced ? cell destruction and development of diabetes in mice. Diabetes, 2010; 59:2603-2611.   PDF
  7. Xenocostas A, Hu H, Chin-Yee N, Lu X, Chin-Yee I, Feng Q. Erythropoietin is equally effective as fresh blood transfusion at reducing infarct size in anemic rats. Critical Care Med. 2010; 38:2215-2221.   PDF
  8. Zhang T, Feng Q. Nitric oxide and calcium signaling on myocardial tumor necrosis factor-alpha expression and cardiac dysfunction in sepsis (review). Can J Physiol Pharmacol. 2010; 88:92-104.   PDF
2009
  1. Burger DE, Xiang F, Hammoud L, Lu X, Feng Q. Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion. Am J Physiology: Heart and Circ Physiol. 2009; 296:H84-H93.   PDF
  2. Peng T, Zhang T, Lu X, Feng Q. JNK1/c-fos inhibits cardiomyocyte TNF-alpha expression via a negative crosstalk with ERK and p38 MAPK in endotoxemia. Cardiovasc Res. 2009; 81:733-741.   PDF
  3. Li N, Lu X, Zhao X, Xiang FL, Xenocostas A, Karmazyn M, Feng Q. Endothelial nitric oxide synthase promotes mesenchymal stromal cell migration towards the ischemic myocardium through upregulation of SDF-1alpha. Stem Cells. 2009; 27:961-970. IF: 7.7   PDF
  4. Hammoud L, Burger DE, Lu X, Feng Q. Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling. Am J Physiology: Cell Physiol. 2009; 296:C735-C745.   PDF
  5. Burger DE, Xiang FL, Hammoud L, Jones DL, Feng Q. Erythropoietin protects the heart from ventricular arrhythmia during ischemia and reperfusion via neuronal nitric oxide synthase. J Pharmacol Exp Ther. 2009; 329:900-907.   PDF
  6. Pocrnich C, Liu H, Feng M, Peng T, Feng Q, Hutnik C. p38 mitogen-activated protein kinase protects human retinal pigment epithelial cells exposed to oxidative stress. Can J Ophthalmol. 2009; 44:431-436.   PDF
  7. Hu H, Li X, Li Y, Wang L, Mehta S, Feng Q, Chen R, Peng T. Calpain-1 induces apoptosis in pulmonary microvascular endothelial cells under septic conditions. Microvasc Res. 2009; 78:33-39.   PDF
  8. Li Y, Li Y, Feng Q, Arnold JMO, Peng T. Calpain activation contributes to hyperglycemia-induced apoptosis in cardiomyocytes. Cardiovasc Res. 2009; 84:100-110.   PDF
  9. Shen E, Li Y, Li Y, Tang CM, Feng Q, Arnold JMO, Peng T. Rac1 is required for cardiomyocyte apoptosis during hyperglycemia. Diabetes. 2009; 58:2386-2395.   PDF
  10. Burger DE, Lu X, Lei M, Xiang F, Hammoud L, Jiang M, Wang H, Jones DL, Sims SM, Feng Q. Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice. Circulation. 2009; 120:1345-1354.   PDF
    11. - Circulation Editors' Picks: Most read articles in arrhythmia and electrophysiology. Circulation 2011;124:e261-e275.
  11. Xiang FL, Lu X, Hammoud L, Zhu P, Robbins J, Feng Q. Cardiomyocyte specific overexpression of human stem cell factor improves cardiac function and survival post myocardial infarction in mice. Circulation. 2009; 120:1065-1074.   PDF
    12. - Circulation Editors' Picks: Most read articles in heart failure. Circulation 2011; 124:e469-e482.
  12. Burger D, Xenocostas A, Feng Q. Molecular basis of cardioprotection by erythropoietin (Review). Current Mol Pharmacol 2009; 2:56-69.   PDF
2008
  1. Peng T, Shen E, Fan J, Zhang Y, Arnold JM, Feng Q. Disruption of phospholipase Cgamma1 signalling attenuates cardiac tumor necrosis factor-alpha expression and improves myocardial function during endotoxemia. Cardiovasc Res. 2008;78:90-97.   PDF IF: 5.9
  2. Detombe SA, Ford NL, Xiang F, Lu X, Feng Q, Drangova M. Longitudinal follow-up of cardiac structure and functional changes in an infarct mouse model using retrospectively gated micro-computed tomography. Investigative Radiology. 2008; 43:520-529.   PDF
  3. Jackson PEM, Feng Q, Jones DL. Nitric oxide depresses connexin 43 after myocardial infarction in mice. Acta Physiol. 2008; 194:23-33.   PDF
2007
  1. Yu G, Peng T, Feng Q, Tyml K. Abrupt reoxygenation of microvascular endothelial cells after hypoxia activates ERK1/2 and JNK1, leading to NADPH oxidase-dependent oxidant production. Microcirculation. 2007; 14(2):125-36.   PDF
  2. Geoghegan-Morphet N, Burger D, Lu X, Sathish V, Peng T, Sims SM, Feng Q. Role of neuronal nitric oxide synthase in lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal mouse cardiomyocytes. Cardiovasc Res. 2007; 75:408-416.   PDF Corrigendum published in Cardiovasc Res. 2009; 81:814.
  3. Hammoud L, Xiang F, Lu X, Brunner F, Leco K, Feng Q. Endothelial nitric oxide synthase promotes neonatal cardiomyocyte proliferation by inhibiting tissue inhibitor of metalloproteinase-3 expression. Cardiovasc Res. 2007; 75:359-68.   PDF
2006
  1. Lu X, Hamilton JA, Shen Ji, Jones DL, Potter RF, Arnold JMO, Feng Q. Role of tumor necrosis factor-alpha in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion. Critical Care Medicine. 2006; 34:484-491.   PDF
  2. Burger DE, Lei M, Geoghegan-Morphet N, Lu X, Xenocostas A, Feng Q. Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase. Cardiovasc Res. 2006; 72:51-59.   PDF
    3. -This paper was one of most downloaded original articles in Cardiovasc Res in 2006.
  3. Lepic E, Burger DE, Lu X, Song W, Feng Q. Lack of endothelial nitric oxide synthase decreases cardiomyocyte proliferation and delays cardiac maturation. Am J Physiol: Cell Physiol. 2006; 291:C1240-C1246.   PDF
  4. Feng Q. Beyond erythropoiesis, the anti-inflammatory effects of erythropoietin (Editorial). Cardiovasc Res. 2006; 71:615-617.   PDF
2005
  1. Peng T, Lu X, Feng Q. NADH oxidase signalling induces cyclooxygenase-2 expression during lipopolysaccharide stimulation in cardiomyocytes. FASEB J. 2005;19:293-295.   PDF
  2. Rui T, Feng Q, Lei M, Peng T, Zhang J, Xu M, Abel ED, Xenocostas A, Kvietys PR. Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1. Cardiovasc Res. 2005; 65:719-727.   PDF
  3. Peng T, Lu X, Feng Q. Pivotal role of gp91phox-containing NADH oxidase in lipopolysaccharide-induced tumor necrosis factor-alpha expression and myocardial depression. Circulation. 2005;111:1637-1644.   PDF
  4. Wang YX, Martin-McNulty B, da Cunha V, Vincelette J, Lu X, Feng Q, Halks-Miller M, Mahmoudi M, Schroeder M, Subramanyam B, Tseng JL, Deng GD, Schirm S, Johns A, Kauser K, Dole WP, Light DR. Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis. Circulation. 2005;111:2219-2226.   PDF
  5. Razavi HM, Hamilton JA, Feng Q. Modulation of apoptosis by nitric oxide: Implications in myocardial ischemia and heart failure (Review). Pharmacology & Therapeutics 2005; 106:147-162.   PDF
  6. Feng Q. Postnatal consequences of prenatal cocaine exposure and myocardial apoptosis: Does cocaine in utero imperil the adult heart? (Commentary) Br J Pharmacol 2005; 144:887-888.   PDF
  7. Xiang F, Feng Q. Regulation of cardiovascular function by nitric oxide (Expert short review). Chinese J Hypertension 2005; 13:673-675.
2004
  1. McCarter SD, Akyea T, Lu X, Bihari A, Scott JR, Badhwar A, Dungey AA, Harris KA, Feng Q, Potter RF. Heme oxygenase induction is a critical mechanism preventing progressive liver injury during the systemic inflammatory response syndrome. Surgery. 2004;136:67-75.   PDF
  2. Tran KL, Lu X, Lei M, Feng Q, Wu Q. Up-regulation of corin gene expression in hypertrophic cardiomyocytes and failing myocardium. Am J Physiol: Heart Circ Physiol. 2004;287:H1625-H1631.   PDF
  3. Moe G, Marin-Garcia J, Konig A, Lu X, Feng Q. In vivo TNF-alpha inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure. Am J Physiol: Heart Circ Physiol. 2004;287:H1813-1820.   PDF
2003
  1. Peng T, Lu X, Lei M, Feng Q. Endothelial nitric oxide synthase enhances lipopolysaccharide-stimulated TNF-alpha expression via cAMP-mediated p38 MAPK pathway in cardiomyocytes. J Biol Chem. 2003;278:8099-8105.   PDF
  2. Peng T, Lu X, Lei M, Moe GW, Feng Q. Inhibition of p38 MAPK decreases myocardial TNF-alpha expression and improves myocardial function and survival during acute endotoxemia in mice. Cardiovasc Res. 2003;59:893-900.   PDF
  3. Rui T, Cepinskas G, Feng Q, Kvietys PR. Delayed preconditioning in cardiac myocytes with respect to neutrophil transendothelial migration: role of SOD and NOS. Cardiovasc Res. 2003;59:901-911.   PDF
2002
  1. Moe GW, Naik G, Kornig A, Lu X, Feng Q. Early and persistent activation of myocardial apoptosis, bax and caspase-3: insights into mechanisms of progression of heart failure. Pathophysiology. 2002;8:183-192.   PDF
  2. Feng Q, Song W, Lu X, Hamilton J, Lei M, Peng T, Yee SP. Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase. Circulation. 2002;106:873-879. *This paper was featured on the cover of Circulation on Aug. 13, 2002.   PDF
  3. Zhao X, Lu X, Feng Q. Deficiency in endothelial nitric oxide synthase impairs myocardial angiogenesis in mice. Am J Physiology: Heart Circ Physiol 2002; 283:H2371-H2378.   PDF
2001
  1. Stathopulos PB, Lu X, Shen J, Scott JA, Hammond JR, McCormack DG, Arnold JMO, Feng Q. Increased L-arginine uptake and inducible nitric oxide activity in aortas of rats with heart failure. Am J Physiol, Heart Circ Physiol. 2001; 280:H859-H867.   PDF
  2. Rui T, Cepinskas G, Feng Q, Ho YS, Kvietys PR. Cardiac myocytes exposed to anoxia/reoxygenation promote neutrophil transendothelial migration. Am J Physiol, Heart Circ Physiol. 2001; 281:H440-H447.   PDF
  3. Feng Q, Lu X, Jones DL, Shen J, Arnold JMO. Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality post myocardial infarction in mice. Circulation. 2001;104:700-704.   PDF
  4. Chen L, Gan XT, Haist JV, Feng Q, Lu X, Chakrabarti S, Karmazyn M. Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide. J Pharmacol Exp Ther. 2001 Aug;298(2):469-76.   PDF
2000
  1. Feng Q, Callow ID, Lambert ML, Arnold JMO. Venous neuropeptide Y receptor responsiveness in patients with chronic heart failure. Clin Pharmacol Ther. 2000; 67:292-298.   PDF
  2. Song W, Lu X, Feng Q. Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes. Cardiovasc Res. 2000; 45:595-602.   PDF
1999
  1. Humphreys RA, Chakrabart S, Haist JV, Feng Q, Arnold JMO, Karmazyn M. Dietary NHE-1 inhibitor cariporide reduces acute response to coronary artery occlusion and reperfusion. Am J Physiol. 1999; 276:H749-H757.
  2. Lambert ML, Callow ID, Feng Q, Arnold JMO. The effects of age on human venous responsiveness in neuropeptide Y. Br J Clin Pharmacol. 1999; 47:83-89.
  3. Feng Q, Fortin AJ, Lu XR, Arnold JMO. Effects of L-arginine on endothelial and cardiac function in rats with congestive heart failure. Eur J Pharmacol. 1999; 376:37-44.
  4. Feng Q, Sun XY, Lu XR, Edvinsson L, Hedner T. Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure. Acta Physiol Scand. 1999; 166:285-291.
1990-1998
  1. Feng Q, Lu XR, Fortin AJ, Pettersson A, Hedner T, Kline RL, Arnold JMO. Elevation of an endogenous inhibitor of nitric oxide synthase in experimental congestive heart failure. Cardiovasc Res. 1998;37:667-675.
  2. Li S, Hwang FL, Feng Q, Liu J, Fan SX, McKenna TM. Overexpression of protein kinase C enhances LPS-induced nitric oxide formation in vascular smooth muscle cells. J Cell Physiol. 1998; 176:402-411.
  3. Callow ID, Campisi P, Lambert ML, Feng Q, Arnold JMO. Enhanced in vivo alpha1- and alpha2-adrenoceptor-mediated venoconstriction with indomethacin in humans. Am J Physiol. 1998; 275:H837-H843.
  4. Feng Q, Bergdahl A, Lu XR, Sun XY, Edvinsson L, Hedner T. Vascular alpha-2 adrenoceptor function is decreased in rats with congestive heart failure. Cardiovasc Res. 1996; 31:577-584.
  5. Feng Q, Sun XY, Hedner T. Cardiovascular responses and interactions by neuropeptide Y in congestive heart failure rat. Blood Pressure. 1996; 5:312-318.
  6. Arnold JMO, Feng Q, Delaney GA, Teasell RW. Increased venous alpha-adrenoceptor responsiveness in quadriplegic patients with autonomic dysreflexia. Clin Autonomic Res. 1995, 5:267-270.
  7. Sun XY, Feng Q, Edvinsson L, Thomas Hedner. Cardiovascular and renal effects of alpha-trinositol in ischemic heart failure rats. Life Sci. 1995; 57:1197-1211.
  8. Bergdahl A, Valemarsson S, Pantev E, Ottoson A, Feng Q, Sun XY, Hedner T, Edvinsson L. Modulation of vascular contractile responses to alpha1 and alpha2 adrenergic and neuropeptide Y1 receptor stimulation in rats with ischaemic heart failure. Acta Physiol Scand. 1995; 154: 429-437.
  9. Feng Q, Carlsson S, Thoren P, Hedner T. Characteristics of renal sympathetic nerve activity in experimental congestive heart failure in the rats. Acta Physiol Scand. 1994; 150:259-266.
  10. Feng Q, Hedner T, Andersson B, Lundberg JM, Waagstein F. Cardiac neuropeptide Y and noradrenaline balance in patients with congestive heart failure. Br Heart J. 1994; 71:261-267.
  11. Fu LX, Sun XY, Feng Q, Liang QM, Hedner T, Hjalmarson A. Down-regulation of endothelin receptors in mesenteric artery in chronic ischemic heart failure in rats. J Cardiovasc Pharmacol. 1993; 22: 177-182.
  12. Sun XY, Hedner T, Feng Q, Edvinsson L. Inhibition of endothelin (ET-1) induced pressor responses by the endothelin (ETA) receptor antagonist FR139317 in the pithed rat. Blood Pressure. 1993; 1: 20-24.
  13. Fu LX, Feng Q, Liang QM, Sun XY, Hedner T, Hjarlmarson A. Hypersensitivity of Gi protein mediated muscarinic receptor adenylyl cyclase in ischaemic heart failure in the rat. Cardiovasc Res. 1993; 27:2065-2070.
  14. Feng Q, Hedner T, Andersson B, Lundberg JM, Waagstein F. Neuropeptide Y is co-released with norepinephrine in patients with congestive heart failure. Chinese J Hyperten. 1993; 1:16-23.
  15. Sun XY, Feng Q, Gong QL, Edvinsson L, Hedner T. Cardiovascular and renal effects of gamma-MSH in spontaneously hypertensive and normotensive Wistar Kyoto rats. Am J Physiol. 1992; 262:R77-R84.
  16. Feng Q, Carlsson S, Thoren P, Hedner T. Effects of clonidine on renal sympathetic nerve activity, natriuresis and diuresis in chronic congestive heart failure rats. J Pharmacol Exp Ther. 1992; 261: 1129-1135.
  17. Feng Q, Carlsson S, Thoren P, Hedner T. Clonidine influences renal sympathetic nerve activity and renal function in experimental heart failure. J Hypertens. 1991; 9:S58-S59.
  18. Sun XY, Feng Q, Edvinsson L, Hedner T. Gamma-melanocyte-stimulating hormone have pressor and natriuretic effects in spontaneously hypertensive and Wistar-Kyoto rats. J Hypertens. 1991; 9:S346-S347.
  19. Feng Q, Hedner T. Endothelium-derived relaxing factor (EDRF) and nitric oxide (NO). I. Physiology, pharmacology and pathophysiological implications. Clin Physiol. 1990; 10:507-426. (Review, 180 refs)
  20. Feng Q, Hedner T. Endothelium-derived relaxing factor (EDRF) and nitric oxide (NO). II. Physiology, pharmacology and pathophysiological implications. Clin Physiol. 1990; 10:503-526. (Review, 174 refs)
  21. Feng Q, Hedner T, Hedner J, Pettersson A. The blunted renal response to atrial natriuretic peptide in congestive heart failure rats is reversed by the alpha2-adrenergic agonist clonidine. J Cardiovasc Pharmacol. 1990; 16:776-782.