Stress of aging viewed from the cardiovascular system
Dr. Edward Lakatta
Laboratory of Cardiovascular Science
National Institute of Aging
National Institutes of Health
Wednesday, April 20, 2011
Dr. Edward Lakatta is the founder and Director of the Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health. He holds appointments as Professor, in the Department of Physiology, University of Maryland School of Medicine, and in the Cardiology Division, Johns Hopkins School of Medicine. His research studies range from molecules to humans, with translation of novel findings into the clinical realm. The goals of his research program include: 1) to identify age related changes within the CV system and to determine the mechanisms for these changes; 2) to determine how aging of the heart and vasculature interacts with chronic disease states to enhance risks for CV diseases; 3) to study basic mechanisms in EC coupling and how these are modulated by receptor signaling pathways in cardiac cells; 4) to elucidate mechanisms of pacemaker activity in SA nodal cells; 5) to elucidate mechanisms that govern cardiac and vascular cell survival; 6) to establish the potentials and limitations of new therapeutic approaches such as changes in lifestyle, novel pharmacologic agents or gene or stem cell transfer techniques in aging or disease states.
Dr. Lakatta has authored 500+ peer-reviewed publications and invited reviews, and has delivered 300+ invited lectures. He is a member of multiple scholarly societies and editorial boards. He has received numerous awards, including the Allied Signal Achievement Award in Aging, the Novartis Prize in Gerontology, the Irving Wright Award of Distinction of the American Federation for Aging Research (AFAR) and the Distinguished Leader Award of the International Society of Heart Research (ISHR).
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