Leaders in Learning: Publications of Faculty & Staff


 

Oncology 2004-2005

Allan, A.L.

Allan, A.L., A.B. Tuck, V.H.C. Bramwell, T.A. Vandenberg, E.W. Winquist, and A.F. Chambers. 2005. Contribution of osteopontin to the development of bone metastasis. Bone Metastasis: Experimental and Clinical Therapeutics. G. Singh, and S.A. Rabbani (Eds.). Totowa, NJ: Humana-IN. 107-124.

Allan, A.L., S.A. Vantyghem, A.B. Tuck, A.F. Chambers, I.H. Chin-Yee, and M. Keeney. 2005. Detection and Quantification of Circulating Tumor Cells in Mouse Models of Human Breast Cancer Using Immunomagnetic Enrichment and Multiparameter Flow Cytometry. Cytometry Part A 65A (1): 4-14.

Vantyghem, S.A., A.L. Allan, C.O. Postenka, W. Al-Katib, M. Keeney, A.B. Tuck, and F. Chambers. 2005. A new model for lymphatic metastasis: development of variant of the MDA-MB-468 human breast cancer cell line that aggressively metatasizes to lymph nodes. Cinical and Experimental Metastasis 22 (4): 351-361.


Ash, R.

Yu, E., A.R. Dar, G.B. Rodrigues, L. Stitt, G.M. Videtic, P. Truong, A. Tomiak, R. Ash, E. Brecevic, R. Inculet, R. Malthaner, M. Vincent, I. Craig, W. Kocha, and M. Lefcoe. 2004. Is extended volume external beam radiation therapy covering the anastomotic site beneficial in post-esophagectomy hight risk patients? Radiotherapy and Oncology 73 (2): 141-148.


Bauman, G.S.

Bauman, G., B. Fisher, E. Cairney, A. Ranger, A.R. Dar, J. Ross, L. Stitt, and D. Macdonald. 2004. Radiotherapy for Pediatric Central Nervous System Tumors: a Regional Cancer Centre Experience. Journal of Neuro-Oncology 68 (3): 285-294.

Bauman, G., E. Winquist, and J. Chin. 2005. A pilot study of regional participation in a videoconferenced multidisciplinary genitourinary tumor board. Canadian Journal of Urology 12 (1): 2532-2536.

Bauman, G., S. Yartsev, T. Coad, B. Fisher, and T. Kron. 2005. Helical tomotherapy for craniospinal radiation. British Journal of Radiology 78 (930): 548-552.

Bauman, G.S., M. Charette, R. Reid, and J. Sathya. 2005. Radiopharmaceuticals for the palliation of painful bone metastases: A systematic review. Radiotherapy and Oncology 75 (3): 258-270.

Craig, T., E. Wong, G. Bauman, J. Battista, and J. Van Dyk. 2005. Impact of Geometric Uncertainties on Evaluation of Treatment Techniques for Prostate Cancer. International Journal of Radiation Oncology Biology Physics 62 (2): 426-436.

Gladwish, A., T. Kron, A. Mcniven, G. Bauman, and J. Van Dyk. 2004. Asymmetric Fan Beams (Afb) for Improvement of the Craniocaudal Dose Distribution in Helical Tomotherapy Delivery. Medical Physics 31 (9): 2443-2448.

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.

Schaly, B., G.S. Bauman, J.J. Battista, and J. Van Dyk. 2005. Validation of Contour-Driven Thin-Plate Splines for Tracking Fraction-to-Fraction Changes in Anatomy and Radiation Therapy Dose Mapping. Physics in Medicine and Biology 50 (3): 459-475.

Wong, E., D.P. D'souza, J.Z. Chen, M. Lock, G. Rodrigues, T. Coad, K. Trenka, M. Mulligan, and G.S. Bauman. 2005. Intensity-Modulated Arc Therapy for Treatment of High-Risk Endometrial Malignancies. International Journal of Radiation Oncology Biology Physics 61 (3): 830-841.

Yartsev, S., T. Kron, L. Cozzi, A. Fogliata, and G. Bauman. 2005. Tomotherapy planning of small brain tumours. Radiation and Oncology 74: 1.


Berg, R.W.

Berg, R.W., T.L.H. Jason, S.F. Fard, T.S. Wong, J. Flynn, M.D. Vincent, P.J. Ferguson, and J. Koropatnick. 2005. Manipulating thymidylate synthase expression using antisense technologies to improve the antitumor efficacy of antifolates. Pteridines 16: 50-51.


Cairney, E.

Bauman, G., B. Fisher, E. Cairney, A. Ranger, A.R. Dar, J. Ross, L. Stitt, and D. Macdonald. 2004. Radiotherapy for Pediatric Central Nervous System Tumors: a Regional Cancer Centre Experience. Journal of Neuro-Oncology 68 (3): 285-294.


Chambers, A.F.

Allan, A.L., A.B. Tuck, V.H.C. Bramwell, T.A. Vandenberg, E.W. Winquist, and A.F. Chambers. 2005. Contribution of osteopontin to the development of bone metastasis. Bone Metastasis: Experimental and Clinical Therapeutics. G. Singh, and S.A. Rabbani (Eds.). Totowa, NJ: Humana-IN. 107-124.

Allan, A.L., S.A. Vantyghem, A.B. Tuck, A.F. Chambers, I.H. Chin-Yee, and M. Keeney. 2005. Detection and Quantification of Circulating Tumor Cells in Mouse Models of Human Breast Cancer Using Immunomagnetic Enrichment and Multiparameter Flow Cytometry. Cytometry Part A 65A (1): 4-14.

Graham, K.C., L.A. Wirtzfeld, L.T. Mackenzie, C.O. Postenka, A.C. Groom, I.C. Macdonald, A. Fenster, J.C. Lacefield, and A.F. Chambers. 2005. Three-Dimensional High-Frequency Ultrasound Imaging for Longitudinal Evaluation of Liver Metastases in Preclinical Models. Cancer Research 65 (12): 5231-5237.

Hedley, B.D., E. Winquist, and A.F. Chambers. 2004. Therapeutic targets for antimetastatic therapy. Expert Opinion on Therapeutic Targets 8 (6): 527-536.

Vantyghem, S.A., A.L. Allan, C.O. Postenka, W. Al-Katib, M. Keeney, A.B. Tuck, and F. Chambers. 2005. A new model for lymphatic metastasis: development of variant of the MDA-MB-468 human breast cancer cell line that aggressively metatasizes to lymph nodes. Cinical and Experimental Metastasis 22 (4): 351-361.

Vantyghem, S.A., S.M. Wilson, C.O. Postenka, W. Al-Katib, A.B. Tuck, and A.F. Chambers. 2005. Dietary Genistein Reduces Metastasis in a Postsurgical Orthotopic Breast Cancer Model. Cancer Research 65 (8): 3396-3403.

Varghese, H.J., L.T. Mackenzie, A.C. Groom, C.G. Ellis, A.F. Chambers, and I.C. Macdonald. 2005. Mapping of the Functional Microcirculation in Vital Organs Using Contrast-Enhanced in Vivo Video Microscopy. American Journal of Physiology-Heart and Circulatory Physiology 288 (1): H185-H193.

Varghese, H.J., L.T. Mackenzie, A.C. Groom, C.G. Ellis, A. Ryan, I.C. MacDonald, and A.F. Chambers. 2004. In-vivo videomicroscopy reveals differential effects of the vascular-targeting agent ZD6126 and the anti-angiogenic agent ZD6474 on vascular function in a liver metastasis model. Angiogenesis 7: 157-164.


Chen, J.Z.

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.


Chin, J.

Bauman, G., E. Winquist, and J. Chin. 2005. A pilot study of regional participation in a videoconferenced multidisciplinary genitourinary tumor board. Canadian Journal of Urology 12 (1): 2532-2536.


D'souza, D.P.

Wong, E., D.P. D'souza, J.Z. Chen, M. Lock, G. Rodrigues, T. Coad, K. Trenka, M. Mulligan, and G.S. Bauman. 2005. Intensity-Modulated Arc Therapy for Treatment of High-Risk Endometrial Malignancies. International Journal of Radiation Oncology Biology Physics 61 (3): 830-841.


Dar, A.R.

Yu, E., A.R. Dar, G.B. Rodrigues, L. Stitt, G.M. Videtic, P. Truong, A. Tomiak, R. Ash, E. Brecevic, R. Inculet, R. Malthaner, M. Vincent, I. Craig, W. Kocha, and M. Lefcoe. 2004. Is extended volume external beam radiation therapy covering the anastomotic site beneficial in post-esophagectomy hight risk patients? Radiotherapy and Oncology 73 (2): 141-148.


Dimattia, G.E.

Gagliardi, A.D., E.Y.W. Kuo, S. Raulic, G.F. Wagner, and G.E. Dimattia. 2005. Human Stanniocalcin-2 Exhibits Potent Growth-Suppressive Properties in Transgenic Mice Independently of Growth Hormone and Igfs. American Journal of Physiology-Endocrinology and Metabolism 288 (1): E92-E105.

Paciga, M., G.E. Dimattia, and G.F. Wagner. 2004. Regulation of Luteal Cell Big Stanniocalcin Production and Secretion. Endocrinology 145 (9): 4204-4212.


Dingle, B.H.

Dingle, B.H. 2004. Pharmacogenomics in Oncology. Oncology Exchange 3 (5) Available at http://www.oncologyex.com/issue/2004/vol3_no4/contents_oct04.html.


Ernst, D.S

Bordette-Radoux, S., R.G. Tozer, R.C. Lohmann, I. Quirt, D.S. Ernst, W. Walsh, N. Wainman, A.D. Colevas, and E.A. Eisenhauer. 2004. Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor in untreated metastatic melanoma. Investigational New Drugs 23 (3): 315-322.

Canil, C.M., M.J. Moore, E. Winquist, T. Baetz, M. Pollak, K. Chi, S. Berry, D.S. Ernst, L. Douglas, M. Brundage, B. Fisher, A. McKenna, and L. Seymour. 2005. Randomized Phase II study of two doses of Gefitinib in hormone-refractory prostate cancer: A trial of the National Cancer Institute of Canada-Clinical Trials Group. Journal of Clinical Oncology 23 (3): 455-460.

Eng, M., L. Taylor, M. Verhoef, B. Donnelly, and D.S. Ernst. 2005. Understanding participation in a trial comparing cryotherapy and radiation treatment. Canadian Journal of Urology 12 (2): 2607-2613.

Ernst, D.S., P. Brasher, P.M. Venner, P. Czaykowsi, M.J. Moore, L. Reyno, E. Winquiste, R. Segal, and D. Hao. 2005. Complian and outcome of patients with satge 1 non-seminomatous germ cell tumors (NSGCT) managed in seven Canadian centres. Canadian Journal of Urology 12 (2): 2575-2580.

Winquist, E., M.J. Moore, K.N. Chi, Ernst D.S., H. Hirte, S. North, J. Powers, W. Walsh, T. Boucher, R. Patton, and L. Seymour. 2005. A multinominal Phase II study of Ionafarnib (SCH 66336) in patients with refractory urothelial cancer. Urology Oncology 23 (3): 143-149.


Fisher, B.

Bauman, G., B. Fisher, E. Cairney, A. Ranger, A.R. Dar, J. Ross, L. Stitt, and D. Macdonald. 2004. Radiotherapy for Pediatric Central Nervous System Tumors: a Regional Cancer Centre Experience. Journal of Neuro-Oncology 68 (3): 285-294.

Bauman, G., S. Yartsev, T. Coad, B. Fisher, and T. Kron. 2005. Helical tomotherapy for craniospinal radiation. British Journal of Radiology 78 (930): 548-552.

Canil, C.M., M.J. Moore, E. Winquist, T. Baetz, M. Pollak, K. Chi, S. Berry, D.S. Ernst, L. Douglas, M. Brundage, B. Fisher, A. McKenna, and L. Seymour. 2005. Randomized Phase II study of two doses of Gefitinib in hormone-refractory prostate cancer: A trial of the National Cancer Institute of Canada-Clinical Trials Group. Journal of Clinical Oncology 23 (3): 455-460.

MacKenzie, M.J., Hirte H.W., L.L. Siu, K. Gelmon, M. Ptaszynski, B. Fisher, and E. Eisenhauer. 2004. A phase I study of OSI-211 and cisplatin as intravenous infusions given on days 1,2, and 3 every 3 weeks in patients with solid cancers. Annual Oncology 15 (4): 665-670.

Maroun, J.A., D. Jonker, L. Seymour, R. Goel, M. Vincent, W. Kocha, C. Cripps, B. Fisher, D. Lister, A. Malpage, G. Chiritescu, and National Cancer Institute of Canada Clinical Trials Group. 2005. A National Cancer Institute of Canada Clinical Trials Group Study--IND.135: Phase I/II study of irinotecan (camtosar), oxaliplatin and raltitrexed (tomudex) (COT) in patients with advanced colorectal cancer. European Journal of Cancer 42 (2): 193-199.

Martenson Jr, J.A., C.G. Willett, Sargent D.J., J.A. Mailliard, J.H. Donohue, L.L. Gunderson, C.R. Thomas Jr, B. Fisher, A.B. Benson 3rd, R. Myerson, and R.M. Goldberg. 2004. Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: Results of intergroup protocol 0130. Journal of Clinical Oncology 22 (16): 3277-3283.

Stupp, R., W.P. Mason, M.J. Van Den Bent, and et.al. 2005. Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma. New England Journal of Medicine 352 (10): 987-996.


Hammond, J.A.

Davis, A.M., B. O'Sullivan, R. Turcotte, R. Bell, C. Catton, P. Chabot, J. Wunder, J.A. Hammond, V. Benk, R. Kandel, K. Goddard, C. Freeman, A. Sadura, B. Zee, A. Day, D. Tue, J. Pater, Canadian Sarcoma Group, and NCI Canada Clinical Trial Group Randomized Trial. 2005. Late radiation morbidity following randomizaton to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma. Radiotherapy and Oncology 75 (1): 48-53.

Devillard, E., J.P. Burton, J.A. Hammond, D. Lam, and G. Reid. 2004. Novel Insight Into the Vaginal Microflora in Postmenopausal Women Under Hormone Replacement Therapy as Analyzed by Pcr-Denaturing Gradient Gel Electrophoresis. European Journal of Obstetrics Gynecology and Reproductive Biology 117 (1): 76-81.

Seal, A., R. Tse, B. Wehrli, J.A. Hamond, and C.L. Temple. 2005. Sentinel Node Biopsy as an adjunct to limb salvage surgery for Epithelioid Sarcoma of the hand. World Journal of Surgical Oncology (3): 41.


Izawa, J.I.

Beasley, K.A., M. Al Omar, A. Shaikh, D. Bochinski, A. Khakhar, J.I. Izawa, R.O. Welch, J.L. Chin, A. Kapoor, and P.P.W. Luke. 2004. Laparoscopic Versus Open Partial Nephrectomy. Urology 64 (3): 458-461.

Gabril, M., J. Xuan, M. Moussa, C.P.N. Dinney, J.L. Chin, and J.I. Izawa. 2004. Characterization of Initiation of Angiogenesis in Early Stages of Prostate Adenocarcinoma Development and Progression in a Transgenic Murine Model. Urology 64 (6): 1233-1237.

Gabril, M.Y., W. Duan, G. Wu, M. Moussa, J.I. Izawa, C.J. Panchal, H. Sakai, and J.W. Xuan. 2005. A Novel Knock-in Prostate Cancer Model Demonstrates Biology Similar to That of Human Prostate Cancer and Suitable for Preclinical Studies. Molecular Therapy 11 (3): 348-362.

Girvan, A.R., P. Chang, I. Van Huizen, M. Moussa, J.W. Xuan, L. Stitt, J.L. Chin, Y. Yamasaki, and J.I. Izawa. 2005. Increased Intratumoral Expression of Prostate Secretory Protein of 94 Amino Acids Predicts for Worse Disease Recurrence and Progression After Radical Prostatectomy in Patients With Prostate Cancer. Urology 65 (4): 719-723.

Mack, D.P., M. Moussa, A. Cook, and J.I. Izawa. 2004. Metastatic Merkel Cell Tumor to the Prostate and Bladder. Urology 64 (1)

Smith, C., L. Sabet, and J.I. Izawa. 2004. Management of Endosalpingiosis of Urinary Bladder. Urology 64 (5)


Kocha, W.

Maroun, J.A., D. Jonker, L. Seymour, R. Goel, M. Vincent, W. Kocha, C. Cripps, B. Fisher, D. Lister, A. Malpage, G. Chiritescu, and National Cancer Institute of Canada Clinical Trials Group. 2005. A National Cancer Institute of Canada Clinical Trials Group Study--IND.135: Phase I/II study of irinotecan (camtosar), oxaliplatin and raltitrexed (tomudex) (COT) in patients with advanced colorectal cancer. European Journal of Cancer 42 (2): 193-199.

Yu, E., A.R. Dar, G.B. Rodrigues, L. Stitt, G.M. Videtic, P. Truong, A. Tomiak, R. Ash, E. Brecevic, R. Inculet, R. Malthaner, M. Vincent, I. Craig, W. Kocha, and M. Lefcoe. 2004. Is extended volume external beam radiation therapy covering the anastomotic site beneficial in post-esophagectomy hight risk patients? Radiotherapy and Oncology 73 (2): 141-148.


Koropatnick, J.

Berg, R.W., T.L.H. Jason, S.F. Fard, T.S. Wong, J. Flynn, M.D. Vincent, P.J. Ferguson, and J. Koropatnick. 2005. Manipulating thymidylate synthase expression using antisense technologies to improve the antitumor efficacy of antifolates. Pteridines 16: 50-51.

Butcher, H.L., W.A. Kennette, O. Collins, R.K. Zalups, and J. Koropatnick. 2004. Metallothionein Mediates the Level and Activity of Nuclear Factor Kappa B in Murine Fibroblasts. Journal of Pharmacology and Experimental Therapeutics 310 (2): 589-598.

Crombet, T., M. Osorio, T. Cruz, C. Roca, R. del Castilla, R. Mon, N. Iznaga-Escobar, R. Figueredo, J. Koropatnick, E. Renginfo, E. Fernandez, D. Alvarez, O. Torres, M. Ramos, I. Leonard, R. Perez, and A. Lage. 2004. Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients. Journal of Clinical Oncology 22 (9): 1646-1654.


Kron, T.

Bauman, G., S. Yartsev, T. Coad, B. Fisher, and T. Kron. 2005. Helical tomotherapy for craniospinal radiation. British Journal of Radiology 78 (930): 548-552.

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.

McNiven, A., and T. Kron. 2004. Interpolation and extrapolation of dose measurements with different detector sizes to improve the spatial resolution of radiotherapy dosimetry as demonstrated for helical tomotherapy. Physics in Medicine and Biology 49 (16): 3665-3674.

McNiven, A., T. Kron, and J. Van Dyk. 2004. A mulleaf collimator phontom for the quality assurance of radiation therapy planning systems and CT simulators. International Journal Radiation Oncology Biology Physics 60 (3): 994-1001.

Moiseenko, V., M. Mulligan, and T. Kron. 2004. Radiation quality of a tomotherapy photon fan beam. Health Physics 87 (2): 166-170.

Yartsev, S., T. Kron, L. Cozzi, A. Fogliata, and G. Bauman. 2005. Tomotherapy planning of small brain tumours. Radiation and Oncology 74: 1.


Lewis, C.

Hamilton, S., V. Venkatesan, T.W. Mattews, C. Lewis, and L. Assis. 2004. Computed tomographic volumetric analysis as a predictor of local control in Laryngeal Cancers treated with conventional radiotherapy. Journal of Otolaryngology 33 (5): 289-294.


Lock, M.

Dinniwell, R., M. Lock, M. Pintilie, A. Fyles, S. Laframboise, D. Depetrillo, W. Levin, L. Manchul, J. Murphy, A. Oza, B. Rosen, J. Sturgeon, and M. Milosevic. 2005. Consolidative abdominopelvic radiotherapy following surgery and chemotherapy for epithelial ovarian cancer. International Journal of Radiation Oncology Biology Physics 62 (1): 104-110.

Lock, M., E. Chow, G.R. Pond, V. Do, C. Danjoux, R. Dinniwell, J. Lea, and A. Bezjak. 2004. Prognostic Factors in Brain Metastases: Can We Determine Patients Who Do Not Benefit From Whole-Brain Radiotherapy? Clinical Oncology 16 (5): 332-338.

Lock, M., and A. Loblaw. 2005. Vitamin E Might Increase Risk of Death. Canadian Family Physician 51: 829-831.

Welsh, J.S., K. Bradley, K.J. Ruchala, T.R. Mackie, R. Manon, R. Patel, P. Wiederhold, M. Lock, S. Hui, and M.P. Mehta. 2004. Megavoltage computed tomography imaging: A potential tool to guide and improve the delivery of thoracic radiation therapy. Clinical Lung Cancer 5 (5): 303-306.

Wong, E., D.P. D'souza, J.Z. Chen, M. Lock, G. Rodrigues, T. Coad, K. Trenka, M. Mulligan, and G.S. Bauman. 2005. Intensity-Modulated Arc Therapy for Treatment of High-Risk Endometrial Malignancies. International Journal of Radiation Oncology Biology Physics 61 (3): 830-841.


Luyt, L.G.

Bigott, H.M., E. Parent, L.G. Luyt, J.A. Katzenellenbogen, and M.J. Welch. 2005. Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors. Bioconjugate Chemistry 16 (2): 255-264.


Macdonald, D.R.

Bauman, G., B. Fisher, E. Cairney, A. Ranger, A.R. Dar, J. Ross, L. Stitt, and D. Macdonald. 2004. Radiotherapy for Pediatric Central Nervous System Tumors: a Regional Cancer Centre Experience. Journal of Neuro-Oncology 68 (3): 285-294.

Ghasemlou, N., K.M. Krol, Macdonald D.R., and M.D. Kawaja. 2004. Comparison of target innervation by sympathetic axons in adult wild type and heterozygous mice for nerve growth factor or its receptor trkA. Journal of Pineal Research 37 (4): 230-240.

Macdonald, D.R., G. Kiebert, M. Prados, A. Yung, and J. Olson. 2004. Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life. Cancer Investigation 23 (2): 138-144.


MacKenzie, M.J.

Hotte, S.J., E.W. Winquist, E. Lamont, M. MacKenzie, E. Vokes, E.X. Chen, S. Brown, G.R. Pond, A. Murgo, and L.L. Siu. 2005. Imatinib mesylate in patients with adenoid cystic cancers of the salivary glands expressing c-kit: A Princess Margaret Hospital Phase II consortium study. Journal of Clinical Oncology 23 (3): 585-590.

MacKenzie, M.J. 2004. Molecular therapy in pancreatic andenocarcinoma: Current status and future directions. Lancet Oncology 5 (9): 541-549.

MacKenzie, M.J., H.W. Hirte, G. Glenwood, J. Maroun, R. Goel, P.P. Major, W.H. Miller Jr, L. Panascie, I.A. Lorimer, G. Batist, S. Matthews, L. Douglas, and L. Seymour. 2005. Phase II trial of ZD1839 (IressaO) 750mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer. Investigational New Drugs 23 (2): 165-170.

MacKenzie, M.J., Hirte H.W., L.L. Siu, K. Gelmon, M. Ptaszynski, B. Fisher, and E. Eisenhauer. 2004. A phase I study of OSI-211 and cisplatin as intravenous infusions given on days 1,2, and 3 every 3 weeks in patients with solid cancers. Annual Oncology 15 (4): 665-670.


Moulin, D.

Moulin, D. 2004. Managing cancer pain: Simple rules, major benefits. Pain Research and Management 9 (4): 180.


Mymryk, J.S.

Flinterman, M., L. Guelen, S. Ezzati-Nik, R. Killick, G. Melino, K. Tominaga, J.S. Mymryk, and J.T.M. Gaken. 2005. E1A activates transcription of p73 and Noxa to induce apoptosis. Journal of Biological Chemistry 280 (7): 5945-5959.

Meng, X.W., P. Webb, Y.F. Yang, M. Shuen, A.F. Yousef, J.D. Baxter, J.S. Mymryk, and P.G. Walfish. 2005. E1A and a Nuclear Receptor Corepressor Splice Variant (N-Cori) Are Thyroid Hormone Receptor Coactivators That Bind in the Corepressor Mode. Proceedings of the National Academy of Sciences of the United States of America 102 (18): 6267-6272.

Rasti, M., R.J.A. Grand, J.S. Mymryk, P.H. Gallimore, and A.S. Turnell. 2005. Recruitment of Cbp/P300, Tata-Binding Protein, and S8 to Distinct Regions at the N Terminus of Adenovirus E1a. Journal of Virology 79 (9): 5594-5605.


Perera, F.

Kron, T., C. Lee, F. Perera, and E. Yu. 2004. Evaluation of Intra- and Inter-Fraction Motion in Breast Radiotherapy Using Electronic Portal Cine Imaging. Technology in Cancer Research & Treatment 3 (5): 443-449.


Rodrigues, G.

Allibhai, Z., G. Rodrigues, E. Brecevic, H.P.H. Neumann, and E. Winquist. 2004. Malignant Pheochromocytoma Associated With Germline Mutation of the Sdhb Gene. Journal of Urology 172 (4): 1409-1410.

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.

Rodrigues, G., A. Bezjak, D. Osoba, P. Catton, D. Tsuji, D. Taylor, and P. Warde. 2004. The relationship of changes in EORTC QLQ-C30 scores to ratings on the subjective significance questionnaire in med with localized prostate cancer. Quality of Life Research 13 (7): 1235-1246.

Rodrigues, G.B. 2005. A prospective study on radiation pneumonitis following conformal radiation therapy in non-small-cell lung cancer: clinical and dosimetric factors analysis. Radiotherapy and Oncology 75 (1): 120-121.

Wong, E., D.P. D'souza, J.Z. Chen, M. Lock, G. Rodrigues, T. Coad, K. Trenka, M. Mulligan, and G.S. Bauman. 2005. Intensity-Modulated Arc Therapy for Treatment of High-Risk Endometrial Malignancies. International Journal of Radiation Oncology Biology Physics 61 (3): 830-841.

Yu, E., A.R. Dar, G.B. Rodrigues, L. Stitt, G.M. Videtic, P. Truong, A. Tomiak, R. Ash, E. Brecevic, R. Inculet, R. Malthaner, M. Vincent, I. Craig, W. Kocha, and M. Lefcoe. 2004. Is extended volume external beam radiation therapy covering the anastomotic site beneficial in post-esophagectomy hight risk patients? Radiotherapy and Oncology 73 (2): 141-148.


Rozmahel, R.

Mastrangelo, P., P.M. Mathews, M.A. Chishti, S.D. Schmidtt, Y.J. Gu, J. Yang, M.J. Mazzella, J. Coomaraswamy, P. Horne, B. Strome, H. Pelly, G. Levesque, C. Ebeling, Y. Jiang, R.A. Nixon, R. Rozmahel, P.E. Fraser, P. St George-Hyslop, G.A. Carlson, and D. Westaway. 2005. Dissociated Phenotypes in Presenilin Transgenic Mice Define Functionally Distinct Gamma-Secretases. Proceedings of the National Academy of Sciences of the United States of America 102 (25): 8972-8977.


Sherar, M.D.

Baddour, R.E., M.D. Sherar, J.W. Hunt, G.J. Csarnota, and M.C. Kolios. 2005. High-frequency ultrasound scattering from microspheres and single cells. Journal of the Acoustical Society of America 117 (2): 934-943.

Chin, L., and M. Sherar. 2004. Changes in the Dielectric Properties of Rat Prostate Ex Vivo at 915 Mhz During Heating. International Journal of Hyperthermia 20 (5): 517-527.

Davidson, S.R.H., I.A. Vitkin, M.D. Sherar, and W.M. Whelan. 2005. Characterization of Measurement Artefacts in Fluoroptic Temperature Sensors: Implications for Laser Thermal Therapy at 810 Nm. Lasers in Surgery and Medicine 36 (4): 297-306.

Sherar, M.D., A.S. Gladman, S.R. Davidson, A.C. Easty, and M.L. Joy. 2004. Infrared thermographic SAR measurements of interstitial hyperthermia applicators: Errors due to thermal conduction and convection. International Journal of Hyperthermia 20 (5): 539-555.

Sherar, M.D., J. Trachtenberg, S.R.H. Davidson, and M.R. Gertner. 2004. Interstitial Microwave Thermal Therapy and Its Application to the Treatment of Recurrent Prostate Cancer. International Journal of Hyperthermia 20 (7): 757-768.

Vlad, R.M., G.J. Czarnota, A. Giles, M.D. Sherar, J.W. Hunt, and M.C. Kolios. 2005. High-Frequency Ultrasound for Monitoring Changes in Liver Tissue During Preservation. Physics in Medicine and Biology 50 (2): 197-213.


Tuck, A.B.

Allan, A.L., A.B. Tuck, V.H.C. Bramwell, T.A. Vandenberg, E.W. Winquist, and A.F. Chambers. 2005. Contribution of osteopontin to the development of bone metastasis. Bone Metastasis: Experimental and Clinical Therapeutics. G. Singh, and S.A. Rabbani (Eds.). Totowa, NJ: Humana-IN. 107-124.

Vantyghem, S.A., A.L. Allan, C.O. Postenka, W. Al-Katib, M. Keeney, A.B. Tuck, and F. Chambers. 2005. A new model for lymphatic metastasis: development of variant of the MDA-MB-468 human breast cancer cell line that aggressively metatasizes to lymph nodes. Cinical and Experimental Metastasis 22 (4): 351-361.


Turley, E.A.

Naor, D., S. Nedvetzki, N. Assayag, R.L. Thurmond, J.F. Huang, and E.A. Turley. 2005. The mechanism of molecular redundancy in autoimmune inflammation in the context of CD44 deficiency. Annals of the New York Academy of Science 1050: 52-63.

Nedvetzki, S., E. Gonen, N. Assayag, R. Reich, R.O. Williams, R.L. Thurmond, J.F. Huang, B.A. Neudecker, F.S. Wang, E.A. Turley, and D. Naor. 2004. Rhamm, a Receptor for Hyaluronan-Mediated Motility, Compensates for Cd44 in Inflamed Cd44-Knockout Mice: a Different Interpretation of Redundancy. Proceedings of the National Academy of Sciences of the United States of America 101 (52): 18081-18086.


Van Dyk, J.

Craig, T., E. Wong, G. Bauman, J. Battista, and J. Van Dyk. 2005. Impact of Geometric Uncertainties on Evaluation of Treatment Techniques for Prostate Cancer. International Journal of Radiation Oncology Biology Physics 62 (2): 426-436.

Gladwish, A., T. Kron, A. Mcniven, G. Bauman, and J. Van Dyk. 2004. Asymmetric Fan Beams (Afb) for Improvement of the Craniocaudal Dose Distribution in Helical Tomotherapy Delivery. Medical Physics 31 (9): 2443-2448.

Kim, B., T. Kron, J. Battista, and J. Van Dyk. 2005. Investigation of Dose Homogeneity for Loose Helical Tomotherapy Delivery in the Context of Breath-Hold Radiation Therapy. Physics in Medicine and Biology 50 (10): 2387-2404.

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.

McNiven, A., T. Kron, and J. Van Dyk. 2004. A Multileaf Collimator Phantom for the Quality Assurance of Radiation Therapy Planning Systems and Ct Simulators. International Journal of Radiation Oncology Biology Physics 60 (3): 994-1001.

Schaly, B., G.S. Bauman, J.J. Battista, and J. Van Dyk. 2005. Validation of Contour-Driven Thin-Plate Splines for Tracking Fraction-to-Fraction Changes in Anatomy and Radiation Therapy Dose Mapping. Physics in Medicine and Biology 50 (3): 459-475.

Song, W., J. Battista, and J. Van Dyk. 2004. Limitations of a Convolution Method for Modeling Geometric Uncertainties in Radiation Therapy: the Radiobiological Dose-Per-Fraction Effect. Medical Physics 31 (11): 3034-3045.


Vandenberg, T.A.

Allan, A.L., A.B. Tuck, V.H.C. Bramwell, T.A. Vandenberg, E.W. Winquist, and A.F. Chambers. 2005. Contribution of osteopontin to the development of bone metastasis. Bone Metastasis: Experimental and Clinical Therapeutics. G. Singh, and S.A. Rabbani (Eds.). Totowa, NJ: Humana-IN. 107-124.

Younus, J., and T. Vandenberg. 2005. A practical overview of Aromatase inhibitors in postmenopausal women with hormone receptor-positive breast cancer. Bulletin of Cancer 92 (4): e39-e44.


Venkatesan, V.

Hamilton, S., V. Venkatesan, T.W. Mattews, C. Lewis, and L. Assis. 2004. Computed tomographic volumetric analysis as a predictor of local control in Laryngeal Cancers treated with conventional radiotherapy. Journal of Otolaryngology 33 (5): 289-294.


Vincent, M.

Berg, R.W., T.L.H. Jason, S.F. Fard, T.S. Wong, J. Flynn, M.D. Vincent, P.J. Ferguson, and J. Koropatnick. 2005. Manipulating thymidylate synthase expression using antisense technologies to improve the antitumor efficacy of antifolates. Pteridines 16: 50-51.

Lapointe, R., R. Letourneau, W. Steward, R.E. Hawkins, G. Batist, M. Vincent, R. Whittom, M. Eatock, J. Jolivet, and M. Moore. 2005. Phase II study of troxacitabine in chemotherapy-naive patients with advanced cancer of the pancreas. Annual Oncology 16 (2): 289-293.

Maroun, J.A., D. Jonker, L. Seymour, R. Goel, M. Vincent, W. Kocha, C. Cripps, B. Fisher, D. Lister, A. Malpage, G. Chiritescu, and National Cancer Institute of Canada Clinical Trials Group. 2005. A National Cancer Institute of Canada Clinical Trials Group Study--IND.135: Phase I/II study of irinotecan (camtosar), oxaliplatin and raltitrexed (tomudex) (COT) in patients with advanced colorectal cancer. European Journal of Cancer 42 (2): 193-199.

Maziak, D.E., A. Gagliardi, A.E. Haynes, J.A. Mackay, W.K. Evans, and CCO PGI Lung Cancer Disease Site Group. 2005. Surgical managemnt of malignant pleural mesothelioma: A systematic review and evidence summary. Lung Cancer 48 (2): 157-169.

Yu, E., A.R. Dar, G.B. Rodrigues, L. Stitt, G.M. Videtic, P. Truong, A. Tomiak, R. Ash, E. Brecevic, R. Inculet, R. Malthaner, M. Vincent, I. Craig, W. Kocha, and M. Lefcoe. 2004. Is extended volume external beam radiation therapy covering the anastomotic site beneficial in post-esophagectomy hight risk patients? Radiotherapy and Oncology 73 (2): 141-148.


Winquist, E.

Allan, A.L., A.B. Tuck, V.H.C. Bramwell, T.A. Vandenberg, E.W. Winquist, and A.F. Chambers. 2005. Contribution of osteopontin to the development of bone metastasis. Bone Metastasis: Experimental and Clinical Therapeutics. G. Singh, and S.A. Rabbani (Eds.). Totowa, NJ: Humana-IN. 107-124.

Allibhai, Z., G. Rodrigues, E. Brecevic, H.P.H. Neumann, and E. Winquist. 2004. Malignant Pheochromocytoma Associated With Germline Mutation of the Sdhb Gene. Journal of Urology 172 (4): 1409-1410.

Bauman, G., E. Winquist, and J. Chin. 2005. A pilot study of regional participation in a videoconferenced multidisciplinary genitourinary tumor board. Canadian Journal of Urology 12 (1): 2532-2536.

Bjarason, G.A., D. Charpentier, R. Wong, R. Goel, L. Douglas, W. Walsh, S. Matthews, S. Dent, L. Deymour, and E. Winquist. 2005. Phase I study of Tomudex and doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98). Investigational New Drugs(See Erratum: Investigational New Drugs 2005 23(2)) 23 (1): 51-56.

Canil, C.M., M.J. Moore, E. Winquist, T. Baetz, M. Pollak, K. Chi, S. Berry, D.S. Ernst, L. Douglas, M. Brundage, B. Fisher, A. McKenna, and L. Seymour. 2005. Randomized Phase II study of two doses of Gefitinib in hormone-refractory prostate cancer: A trial of the National Cancer Institute of Canada-Clinical Trials Group. Journal of Clinical Oncology 23 (3): 455-460.

Ernst, D.S., P. Brasher, P.M. Venner, P. Czaykowsi, M.J. Moore, L. Reyno, E. Winquiste, R. Segal, and D. Hao. 2005. Complian and outcome of patients with satge 1 non-seminomatous germ cell tumors (NSGCT) managed in seven Canadian centres. Canadian Journal of Urology 12 (2): 2575-2580.

Hedley, B.D., E. Winquist, and A.F. Chambers. 2004. Therapeutic targets for antimetastatic therapy. Expert Opinion on Therapeutic Targets 8 (6): 527-536.

Hotte, S.J., E.W. Winquist, E. Lamont, M. MacKenzie, E. Vokes, E.X. Chen, S. Brown, G.R. Pond, A. Murgo, and L.L. Siu. 2005. Imatinib mesylate in patients with adenoid cystic cancers of the salivary glands expressing c-kit: A Princess Margaret Hospital Phase II consortium study. Journal of Clinical Oncology 23 (3): 585-590.

Hotte, S.J., E.W. Winquist, M. Moore, E.X. Chen, S. Brown, G.R.D.J.E. Pond, and H.W. Hirte. 2005. Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: A Princess Margaret Hospital Phase II Consortium study. Annual Oncology 17 (2): 344-350.

Winquist, E., M.J. Moore, K.N. Chi, Ernst D.S., H. Hirte, S. North, J. Powers, W. Walsh, T. Boucher, R. Patton, and L. Seymour. 2005. A multinominal Phase II study of Ionafarnib (SCH 66336) in patients with refractory urothelial cancer. Urology Oncology 23 (3): 143-149.

Winquist, E., E. Vokes, M.J. Moore, L.P. Schumm, K. Hoving, and W.M. Stadler. 2005. A phase II studey of oxaliplatin in urothelial cancer. Urology Oncology 23 (3): 150-154.

Winquist, E., J.J. Wilson, M. Doreen, R. Wong, D. Jonker, and N. Iscoe. 2004. A 3-week gemcitabine-cisplatin regimen for metastatic urothelial cancer. Canadian Journal of Urology 11 (6): 2445-2449.


Wong, E

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.

Wong, E., D.P. D'souza, J.Z. Chen, M. Lock, G. Rodrigues, T. Coad, K. Trenka, M. Mulligan, and G.S. Bauman. 2005. Intensity-Modulated Arc Therapy for Treatment of High-Risk Endometrial Malignancies. International Journal of Radiation Oncology Biology Physics 61 (3): 830-841.


Younus, J

Younus, J., and T. Vandenberg. 2005. A practical overview of Aromatase inhibitors in postmenopausal women with hormone receptor-positive breast cancer. Bulletin of Cancer 92 (4): e39-e44.

Younus, J., S. Welch, and Granville H. 2005. A case report of using hypnosis to treat hot flases and rheumatic symptoms. Clinical Practice Review - Case Reports (6): 103-106.


Yu, E.

Kron, T., G. Grigorov, E. Yu, S. Yartsev, J.Z. Chen, E. Wong, G. Rodrigues, K. Trenka, T. Coad, G. Bauman, and J. Van Dyk. 2004. Planning evaluation of radiotherapy for complex lung cancer cases using helical tomotherapy. Physics in Medicine and Biology 49 (16): 3675-3690.

Kron, T., C. Lee, F. Perera, and E. Yu. 2004. Evaluation of Intra- and Inter-Fraction Motion in Breast Radiotherapy Using Electronic Portal Cine Imaging. Technology in Cancer Research & Treatment 3 (5): 443-449.

Maziak, D.E., B.R. Markman, J.A. MacKay, W.K. Evans, and CCOPGI Lung Cancer Disease Site Group. 2004. Photodynamic therapy in nonsmall cell lung cancer: A systematic review. Annual Thoracic Surgery 77 (4): 1484-1491.

Tai, P., and E. Yu. 2004. Lung cancer trends Part 1: North America. Current Oncology 11 (4): 127-138.

Tai, P., E. Yu, R. Shiels, and J. Tonita. 2005. Long term survival rates of Laryngeal cancer patients treated by radiation and surgery, radiation alone, and surgery alone, studied by lognormal and Kaplan-Meier survival methods. Medical Physics 5 (1): 13.

Tai, P., E. Yu, V. Vinh-hung, G. Cserni, and G. Vlastos. 2004. Malignant Pleural Mesothelioma: Worldwide Trends. Current Oncology 11 (3): 102-116.

Tai, P., E. Yu, V. Vinh-Hung, G. Cserni, and G. Vlastos. 2004. Survival of Patients With Metastatic Breast Cancer: Twenty-Year Data From Two Seer Registries. BMC Cancer 4 (60): doi:10.1186/1471-2407-4-60.

Tai, P., E.W. Yu, G. Cserni, G. Vlastos, M. Royce, I. Kunkler, and V. Vinh-Hung. 2005. Minimum Follow-up Time Required for the Estimation of Statistical Cure of Cancer Patients: Verification Using Data From 42 Cancer Sites in the Seer Database. BMC Cancer 5 (48)

Yu, E., A.R. Dar, G.B. Rodrigues, L. Stitt, G.M. Videtic, P. Truong, A. Tomiak, R. Ash, E. Brecevic, R. Inculet, R. Malthaner, M. Vincent, I. Craig, W. Kocha, and M. Lefcoe. 2004. Is extended volume external beam radiation therapy covering the anastomotic site beneficial in post-esophagectomy hight risk patients? Radiotherapy and Oncology 73 (2): 141-148.