Leaders in Learning: Publications of Faculty & Staff


Physiology & Pharmacology 2003-2004


BAI, D.

Kolaj, M., D. Bai, and L.P. Renaud. 2004. GABA beta Receptor Modulation of Rapid Inhibitory and Excitatory Neurotransmission From Subfornical Organ and Other Afferents to Median Preoptic Nucleus Neurons. Journal of Neurophysiology 92 (July): 111-122.

Sattelle, D.B., D. Bai, H.H. Chen, J.M. Skeer, S.D. Buckingham, and J.J. Rauh. 2003. Bicuculline-insensitive GABA-gated Chloride channels in the larval nervous system of the moth Manduca sexta. Invert Neuroscience 5: 37-43.


FERGUSON, P.J.

Ferguson, P.J., E. Kurowska, D.J. Freeman, A.F. Chambers, and D.J. Koropatnick. 2004. A flavonoid fraction from cranberry extract inhibits proliferation of human tumour cell lines. Journal of Nutrition 134: 1529-1535.


GARLAND, S.J.

Garland, S.J., D.A. Willems, T.D. Ivanova, and K.J. Miller. 2003. Recovery of standing balance and functional mobility after stroke. Archives of Physical Medicine Rehabilitation 84 (Dec): 1753-1759.

Gossen, E.R., T.D. Ivanova, and S.J. Garland. 2003. Factors affecting the stability of the spike-triggered averaged force in the human first dorsal interosseus muscle. Journal of Neuroscience Methods 126: 155-164.

Gossen, E.R., T.D. Ivanova, and S.J. Garland. 2003. The time course of the motoneurone afterhyperpolarization is related to motor unit twitch speed in human skeletal muscle. Journal of Physiology 522 (2): 657-664.

Mochizuki, G., T.D. Ivanova, and S.J. Garland. 2004. Postural muscle activity during bilateral and unilateral arm movements at different speeds. Experimental Brain Research 155: 352-361.


GRATTON, R.J.

Gratton, R.J., M. Gluszynski, D.M. Mazzuca, K. Nygard, and V.K.M. Han. 2003. Adrenomedullin messenger ribonucleic acid expression in the placentae of normal and preeclamptic pregnancies. The Journal of Clinical Endocrinology and Metabolism 88 (12): 6048-6055.

Gratton, R.J., M. Gluszynski, K. Nygard, D.M. Mazzuca, C.H. Graham, and V.K.M. Han. 2004. Reducing agent and tunicamycin-responsive protein (RTP) mRNA expression in the placentae of normal and pre-eclamptic women. Placenta 25: 62-69.


HAMMOND, J.R.

Hammond, J.R., and R.G.E. Archer. 2004. Interaction of the Novel Adenosine Uptake Inhibitor 3-[6,7-Diethoxy-2-morpholinoquinazolin-4-yl) piperidin-4-yl]-1,6-dimethyl-2,4(1H, 3H)-quinazolinedione Hydrochloride (KF24345) with the es and ei Subtypes of Equilibrative Nucleoside Transporters. The Journal of Pharmacology and Experimental Therapeutics 308 (3): 1083-1093.

Hammond, J.R., M. Stolk, R.G.E. Archer, and K. McConnell. 2004. Phamacological analysis and molecular cloning of the canine equilibrative nucleoside transporter 1. European Journal of Pharmacology 491: 9-19.


HENRY, J.

Sharma, S.K., K. Yashpal, M.E. Fundytus, F. Sauriol, J.L. Henry, and T.J. Coderre. 2003. Alterations in brain metabolism induced by chronic morphine treatment: NMR studies in rat CNS. Neurochemical Research 28 (9): 1369-1373.


HILL, D.J.

Boujendar, S., E. Arany, D.J. Hill, C. Remacle, and B. Reusens. 2003. Taurine supplementation during fetal life reverses the vascular impairment caused to the endocrine pancreas by a low protein diet. Journal of Nutrition 133: 2820-2825.

Hess, D., L. Li, S. Sakano, D.J. Hill, B. Strutt, S. Thyssen, D. Gray, and B. Bhatia. 2003. Bone marrow derived stem cells rescue hyperglycemia by regeneration of recipient islets. Nature Biotechnology 21: 763-770.

Hill, D.J. 2003. Regulation of fetal growth. Textbook of Diabetes and Pregnancy. M. Hod, L. Jovanovic, A. De Leiva, G.C. Di Renzo, and O. Langer. London, UK: Martin Dunitz. 222-239.

Srinivasan, M., S.G. Laychock, D.J. Hill, and M.S. Patel. 2003. Neonatal nutrition: Metabolic programming of pancreatic islets and obesity. Experimental Biology and Medicine 228: 15-23.

Wang, J.F., and D.J. Hill. 2004. A tissue culture model for the production of endocrine precursor cells from pancreatic ducts of the neonatal rat. Journal of Endocrinology E-Publication (March ) Available at http://joe.endocrinology-journals.org/.


JONES, D.L.

Skanes, A.C., Klein. G.J, G. Guiraudon, A.H. Menkis, D.L. Jones, A.D. Krahn, and R. Yee. 2003. Hybrid approach for minimally-invasive operative therapy of arrhythmias. Journal of Interventional Cardiac Electrophysiology 9: 289-294.


KENNEDY, T.G.

Kennedy, T. 2003. Decidualization. Encyclopedia of Hormones. USA: Elsevier. 379-385.

Simmons, D.G., and T.G. Kennedy. 2004. Rat endometrial Vdup1 expression: changes related to sensitization for the decidual cell reaction and hormonal control. Reproduction 127: 475-482.


KIDDER, G.M.

Veitch, G.I., J.E.I.S.Q. Gittens, and D.W.K.G.M. Laird. 2004. Selective assembly of connexin37 into heterocellular gap junctions at the oocyte/granulosa cell interface. Journal of Cell Science 117 (13): 2699-2707.


LECO, K.J.

Gill, S.E., M.C. Pape, R. Khokha, A.J. Watson, and K.J. Leco. 2003. A null mutation for Tissue Inhibitor of Metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Developmental Biology 261: 313-323.

Martin, E.L., B.Z. Moyer, M.C. Pape, B. Starcher, K.J. Leco, and R.A.W. Veldhuizen. 2003. Negative impact of tissue inhibitor of metalloproteinase-3 null mutation on lung structure and function in response to sepsis. American Journal of Physiology 285 (Dec): L1222-L1232.


LEUNG, S. L.

Leung, S.L., and B. Shen. 2004. Glutamatergic Synaptic Transmission Participates in Generating the Hippocampal EEG. Hippocampus 14: 510-525.

Leung, S.L., B. Shen, N. Rajakumar, and J. Ma. 2003. Cholinergic Activity Enhances Hippocampal Long-Term Potentiation in CA1 during Walking in Rats. The Journal of Neuroscience 23 (October): 9297-9304.

Liu, X., and S.L. Leung. 2003. Partial hippocampal kindling increases GABA beta receptor-mediated postsynaptic currents in CA1 pyramidal cells. Epilepsy Research 57: 33-47.

Ma, J., and L.S. Leung. 2004. Schizophrenia-like behavioural changes after partial hippocampal kindling. Brain Research 997: 111-118.

Rajakumar, N., S.L. Leung, J. Ma, B. Rajakumar, and W. Rushlow. 2004. Altered Neurotrophin Receptor Function in the Developing Prefrontal Cortex Leads to Adult-Onset Dopaminergic Hyperresponsivity and Impaired Prepulse Inhibition of Acoustic Startle. Biological Psychiatry 55: 797-803.


LEWIS, J.F.

Bailey, T., K. DaSilva, J. Lewis, K. Rodriguez-Capote, F. Possmayer, and R. Veldhuizen. 2003. The physiological and inflammatory response to treatment with an oxidized surfactant in a rat model of surfactant deficiency. Journal of Applied Physiology 96: 1674-1680.

Bailey, T.C., K.A. Da Silva, J.F. Lewis, K. Rodriguez-Capote, F. Possmayer, and R.A.W. Veldhuizen. 2004. Physiological and inflammatory response to instillation of an oxidized surfactant in a rat model of surfactant deficiency. Journal of Applied Physiology 96 (May): 1674-1680.

Bosma, K., R. Kao, T. Charyk-Stewart, R. Veldhuizen, L. McCaig, L.-J. Yao, and J. Lewis. 2004. Bronchoalveolar lavage analysis in mechanically ventilated trauma patients. American Journal of Respiratory Critical Care Medicine 167 (7): A682.

Easley, R.B., J.F. Lewis, L.A. McCaig, G. McLennan, K.C. Beck, M.K. Fuld, and B.A. Simon. 2004. Regional bronchioalveolar lavage (BAL) in a saline lavage model of acute lung injury (ALI) demonstrates regional differences in surfactant behaviour. American Journal of Respiratory Critical Care Medicine 169 (9): A544.

Kerr, C.L., L.A. McCaig, R.A.W. Veldhuizen, and J.F. Lewis. 2003. High-frequency oscillation and exogenous surfactant administration in lung-injured adult sheep. Critical Care Medicine 31 (10): 2520-2526.

Korneck, A., D. Engelberts, H. Frndova, J. Belik, J. Lewis, and B. Kavanagh. 2004. Pulmonary vascular remodeling potentiates ventilator-induced lung injury. American Journal of Respiratory Critical Care Medicine 167 (7): A787.

Laffey, J.G., D. Engelberts, M. Duggan, R. Veldhuizen, J.F. Lewis, and B.P. Kavanagh. 2003. Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Critical Care Medicine 31 (11): 2634-2640.

Laffey, J.G., Engelberts D., Veldhuizen R., J. Lewis, and B.P. Kavanagh. 2003. Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Critical Care Medicine 31 (11): 26347-2640.

Lewis, J.F., and A. Brackenbury. 2003. Role of exogenous surfactant in acute lung injury. Critical Care Medicine 31 (4): S324-S328.

Taut, F.J.H., G. Rippin, T.D. Bethke, J.F. Lewis, R.G. Spragg, and W. Seeger. 2004. Meta-analysis of Venticute (rSP-C surfactant) studies suggests treatment benefit for patients with severe direct ARDS. American Journal of Respiratory Critical Care Medicine 169 (7): A783.

Zenri, H., K. Rodriquez-Capote, L. McCaig, L. Yao, A. Brackenbury, F. Possmayer, R. Veldhuizen, and J. Lewis. 2004. Hyperoxia exposure impairs surfactant function and metabolism. Critical Care Medicine 32 (5): 1155-1160.


MCCORMACK, D.G.

Massel, D., McCormack D.G., Lewis J.F., and J. Mahon. 2003. Research of the holiday kind. Stableford: Equitable scoring system or quality of life measure? Canadian Medical Association Journal 167: 1337-1340.

McCormack D.G. 2003. Therapy for primary pulmonary hypertension. Canadian Respiatory Journal 10: 169.

Razavi, H., L.F. Wang, S. Weicker, M. Rohan, D.G. McCormack, and S. Mehta. 2004. Pulmonary neutrophil infiltration in murine sepsis: Role of neutrophil iNOS. American Journal of Respiatory Critical Care Medicine 170: 227-233.

Yaghi, A., J.R. Bend, C.D. Webb, C.D. Zeldin, S. Weicker, S. Mehta, and McCormack D.G. 2004. Excess nitric oxide decreases cytochrome P450 2J4 (CYP2J4) content and P450-dependent arachidonic acid metabolism in lungs of rats with acute pneumonia. American Journal of Physiology 286: L1260-67.

Yaghi, A., Bradbury J.A., Zeldin D.C., S. Mehta, J.R. Bend, and McCormack D.G. 2003. Pulmonary cytochrome P450 2J4 (CYP2J4) is reduced in a rat model of acute Pseudomonas pneumonia. American Journal of Physiology: Lung Cellular and Molecular Physiology 285 (5): L1099-1105.


RICHARDSON, B.S.

Agrawal, S.K., F. Doucette, R. Gratton, B. Richardson, and R. Gagnon. 2003. Intrapartum computerized fetal heart rate parameters and metabolic acidosis at birth. Obstetrics and Gynecology 102 (4): 731-738.

Czikk, M.J., J.C. Sweeley, J.H. Homan, J.R. Milley, and B.S. Richardson. 2003. Cerebral leucine uptake and protein synthesis in the near-term ovine fetus: relation to fetal behavioural state. American Journal of Physiology 284: R200-R207.

Kaneko, M., S. White, J. Homan, and B. Richardson. 2003. Cerebral blood flow and metabolism in relation to electrocortical activity with severe umbilical cord occlusion in the near-term ovine fetus. American Journal of Obstetrics and Gynecology 188: 961-972.


RIEDER, M.J.

Choonara, I., and M.J. Rieder. 2004. Drug toxicity and adverse drug reactions in children - A brief historical review. Introduction to Paediatric and Perinatal Drug Therapy. I. Choonara, A.J. Nunn, and G. Kearns. Nottingham: Nottingham University Press. 1-13.

Matsui, D., C. Kwan, E. Steer, and M.J. Rieder. 2003. The trials and tribulations of doing drug research in children. Canadian Medical Association Journal (Nov): 1033-1034.

Rieder, M.J. 2004. Allergic reactions to drugs. Conn's Current Therapy 2004. 56 ed. H.R. Conn, R.E. Rakel, and E.T. Bope. New York: Saunders. 815-819.

Rieder, M.J. 2004. Creepy crawlies and kids. The Canadian Journal of CME (Feb): 95-100.

Rieder, M.J. 2004. Drug excretion during lactation. Fetal and Neonatal Physiology. 1. 3 ed. R.A. Polin, W.W. Fox, and S.H. Abman. Philadelphia: Saunders. 249-258.


TEPPERMAN, B.

Conte, M., B. Soper, Q. Chang, and B. Tepperman. 2004. The role of PKC gamma and PKC epsilon in the neonatal rat colon in response to hypoxia challenge. Pediatric Research 55 (1): 27-33.


VELDHUIZEN, R.A.W.

Bailey, T.C., K.A. Da Silva, J.F. Lewis, K. Rodriguez-Capote, F. Possmayer, and R.A.W. Veldhuizen. 2004. Physiological and inflammatory response to instillation of an oxidized surfactant in a rat model of surfactant deficiency. Journal of Applied Physiology 96 (May): 1674-1680.

Kerr, C.L., L.A. McCaig, R.A.W. Veldhuizen, and J.F. Lewis. 2003. High-frequency oscillation and exogenous surfactant administration in lung-injured adult sheep. Critical Care Medicine 31 (10): 2520-2526.

Laffey, J.G., D. Engelberts, M. Duggan, R. Veldhuizen, J.F. Lewis, and B.P. Kavanagh. 2003. Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Critical Care Medicine 31 (11): 2634-2640.

Martin, E.L., B.Z. Moyer, M.C. Pape, B. Starcher, K.J. Leco, and R.A.W. Veldhuizen. 2003. Negative impact of tissue inhibitor of metalloproteinase-3 null mutation on lung structure and function in response to sepsis. American Journal of Physiology 285 (Dec): L1222-L1232.

Panda, A.K., K. Nag, R.R. Harbottle, K. Rodriguez-Capote, R.A.W. Veldhuizen, N.O. Peterson, and F. Possmayer. 2004. Effect of acute lung injury on structure and function of pulmonary surfactant films. American Journal of Respiratory Cell and Molecular Biology 30: 641-650.


WANG, R.

Yaspal, N.K., L. Jinming, and R. Wang. 2004. Characterization of c-Kit and nestin expression during islet cell development in the prenatal and postnatal rat pancreas. Developmental Dynamics 229: 813-825.