TEMPLATE

Leaders in Learning: Publications of Faculty & Staff

Medicine 2002-2003

ADAMS, P.C.

Adams, P.C. 2003. Lessons from liver transplantation: flip, flop, and why? Gut 52 (3): 318.

Harrison, H., and P.C. Adams. 2002. Hemochromatosis. Common genes, uncommon illness? Canadian Family Physician 48: 1326-33.

McGrath, J.S., Y. Deugnier, R. Moirand, A.M. Jouanolle, S. Chakrabarti, and P.C. Adams. 2002. A nomogram to predict C282Y hemochromatosis. The Journal of Laboratory and Clinical Medicine 140 (1): 6-8.

McLaren, C.E., J.C. Barton, P.C. Adams, E.L. Harris, R.T. Acton, N. Press, D.M. Reboussin, G.D. McLaren, P. Sholinsky, A.P. Walker, V.R. Gordeuk, C. Leiendecker-Foster, F.W. Dawkins, J.H. Eckfeldt, B.G. Mellen, M. Speechley, and E. Thomson. 2003. Hemochromatosis and Iron Overload Screening (HEIRS) study design for an evaluation of 100,000 primary care-based adults. The American Journal of the Medical Sciences 325 (2): 53-62.

BAILEY, D.G.

Bailey, D.G., G.K. Dresser, and J.R. Bend. 2003. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Clinical Pharmacology and Therapeutics 73 (6): 529-37.

Dresser, G.K., V. Wacher, S. Wong, H.T. Wong, and D.G. Bailey. 2002. Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. Clinical Pharmacology and Therapeutics 72 (3): 247-55.

BEHME, M.T.

Behme, M.T., J. Dupre, and T.J. McDonald. 2003. Glucagon-like peptide 1 improved glycemic control in type 1 diabetes. BMC Endocrine Disorders 3 (1): 3.

BELL, D.A.

Hill, J.A., D. Wang, A.M. Jevnikar, E. Cairns, and D.A. Bell. 2003. The relationship between predicted peptide-MHC class II affinity and T-cell activation in a HLA-DRbeta1*0401 transgenic mouse model. Arthritis Research and Therapy 5 (1): R40-8.

Wang, D., J.A. Hill, A.M. Jevnikar, E. Cairns, and D.A. Bell. 2002. Induction of transient arthritis by the adoptive transfer of a collagen II specific Th1 clone to HLA-DR4 (B1*0401) transgenic mice. Journal of Autoimmunity 19 (1-2): 37-43.

BLAKE, P.G.

Blake, P.G. 2003. Adequacy of dialysis revisited. Kidney International 63 (4): 1587-99.

Blake, P.G., and D.C. Mendelssohn. 2003. Quality of care in profit vs not-for-profit dialysis centers. JAMA 289 (23): 3088-9; author reply 3089-90.

Blake, P.G., and T.F. Parker 3rd. 2003. Report of the International Society of Nephrology: North American Renal Disaster Response Task Force. Advances in Renal Replacement Therapy 10 (2): 100-3.

Perez, R.A., P.G. Blake, K.A. Jindal, K. Badovinac, L. Trpeski, and S.S. Fenton. 2003. Changes in peritoneal dialysis practices in Canada 1996-1999. Peritoneal Dialysis International 23 (1): 53-7.

Wazny, L.D., B.B. Stojimirovic, P. Heidenheim, and P.G. Blake. 2002. Factors influencing erythropoietin compliance in peritoneal dialysis patients. American Journal of Kidney Diseases 40 (3): 623-8.

BORRIE, M.J.

Wells, J.L., J.A. Seabrook, P. Stolee, M.J. Borrie, and F. Knoefel. 2003. State of the art in geriatric rehabilitation. Part I: review of frailty and comprehensive geriatric assessment. Archives of Physical Medicine and Rehabilitation 84 (6): 890-7.

Wells, J.L., J.A. Seabrook, P. Stolee, M.J. Borrie, and F. Knoefel. 2003. State of the art in geriatric rehabilitation. Part II: clinical challenges. Archives of Physical Medicine and Rehabilitation 84 (6): 898-903.

BOUGHNER, D.R.

Cimini, M., K.A. Rogers, and D.R. Boughner. 2002. Aortic valve interstitial cells: an evaluation of cell viability and cell phenotype over time. The Journal of Heart Valve Disease 11 (6): 881-7.

Nadkarni, S.K., H. Austin, G. Mills, D. Boughner, and A. Fenster. 2003. A pulsating coronary vessel phantom for two- and three-dimensional intravascular ultrasound studies. Ultrasound in Medicine & Biology 29 (4): 621-8.

CAIRNS, E.

CHIN-YEE, I.

Brown, W., M. Keeney, I. Chin-Yee, K. Johnson, K. Lantis, W. Finn, N. Wolfe, and S. Kaplan. 2003. Validation of body fluid analysis on the Coulter LH 750. Laboratory Hematology 9 (3): 155-9.

Chin-Yee, I.H., M. Keeney, A.K. Stewart, A. Belch, I. Bence-Buckler, S. Couban, K. Howson-Jan, M. Rubinger, D. Stewart, R. Sutherland, V. Paragamian, M. Bhatia, and R. Foley. 2002. Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34(+) absolute counts and subsets. Bone Marrow Transplant 30 (12): 851-60.

Eichelbronner, O., M. D'Almeida, A. Sielenkamper, W.J. Sibbald, and I.H. Chin-Yee. 2002. Increasing P(50) does not improve DO(2CRIT) or systemic VO(2) in severe anemia. American Journal of Physiology: Heart and Circulatory Physiology 283 (1): H92-101.

Eichelbronner, O., W.J. Sibbald, and I.H. Chin-Yee. 2003. Intermittent flow increases endotoxin-induced adhesion of human erythrocytes to vascular endothelial cells. Intensive Care Medicine 29 (5): 709-14.

Hess, D.A., K.D. Levac, F.N. Karanu, M. Rosu-Myles, M.J. White, L. Gallacher, B. Murdoch, M. Keeney, P. Ottowski, R. Foley, I. Chin-Yee, and M. Bhatia. 2002. Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor. Blood 100 (3): 869-78.

Luk, C.S., L.A. Gray-Statchuk, G. Cepinkas, and I.H. Chin-Yee. 2003. WBC reduction reduces storage-associated RBC adhesion to human vascular endothelial cells under conditions of continuous flow in vitro. Transfusion 43 (2): 151-6.

Morita, Y., I. Chin-Yee, P. Yu, W.J. Sibbald, and C.M. Martin. 2003. Critical oxygen delivery in conscious septic rats under stagnant or anemic hypoxia. American Journal of Respiratory and Critical Care Medicine 167 (6): 868-72.

CLARK, W.F.

Hejaili, F.F., L.M. Moist, and W.F. Clark. 2003. Treatment of lupus nephritis. Drugs 63 (3): 257-74.

DHANVANTARI, S.

Zhang, C.F., S. Dhanvantari, H. Lou, and Y.P. Loh. 2003. Sorting of carboxypeptidase E to the regulated secretory pathway requires interaction of its transmembrane domain with lipid rafts. The Biochemical Journal 369 (Pt 3): 453-60.

DRESSER, G.

Kurowska, E.M., G. Dresser, L. Deutsch, E. Bassoo, and D.J. Freeman. 2003. Relative bioavailability and antioxidant potential of two coenzyme q10 preparations. Annals of Nutrition & Metabolism 47 (1): 16-21.

Kurowska, E.M., G.K. Dresser, L. Deutsch, D. Vachon, and W. Khalil. 2003. Bioavailability of omega-3 essential fatty acids from perilla seed oil. Prostaglandins, Leukotrienes, and Essential Fatty Acids 68 (3): 207-12.

DREYER, J.F.

Carter, A.J., P.S. Keane, and J.F. Dreyer. 2002. Transport refusal by hypoglycemic patients after on-scene intravenous dextrose. Academic Emergency Medicine 9 (8): 855-7.

FEAGAN, B.G.

Alfadhli, A.A., J.W. McDonald, and B.G. Feagan. 2003. Methotrexate for induction of remission in refractory Crohn's disease. Cochrane Database of Systematic Reviews (1): CD003459.

Feagan, B.G. 2002. The efficacy, safety and acceptance of autologous blood donation as a blood conservation strategy. Vox Sanguinis 83 Suppl 1: 11-2.

Feagan, B.G., and D. Sachar. 2002. What do I do in my practice that isn't evidence based? Inflammatory Bowel Diseases 8 (6): 422-5; discussion 426-7.

Kane, S.V., P. Schoenfeld, W.J. Sandborn, W. Tremaine, T. Hofer, and B.G. Feagan. 2002. The effectiveness of budesonide therapy for Crohn's disease. Alimentary Pharmacology & Therapeutics 16 (8): 1509-17.

Steinhart, A.H., B.G. Feagan, C.J. Wong, M. Vandervoort, S. Mikolainis, K. Croitoru, E. Seidman, D.J. Leddin, A. Bitton, E. Drouin, A. Cohen, and G.R. Greenberg. 2002. Combined budesonide and antibiotic therapy for active Crohn's disease: a randomized controlled trial. Gastroenterology 123 (1): 33-40.

FELDMAN, R.D.

Bhattacharya, M., P.H. Anborgh, A.V. Babwah, L.B. Dale, T. Dobransky, J.L. Benovic, R.D. Feldman, J.M. Verdi, R.J. Rylett, and S.S. Ferguson. 2002. Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization. Nature Cell Biology 4 (8): 547-55.

Campbell, N.R., D. Drouin, and R.D. Feldman. 2002. The 2001 Canadian hypertension recommendations: take-home messages. CMAJ 167 (6): 661-8.

FERGUSON, K.A.

Ferguson, K.A. 2003. The role of oral appliance therapy in the treatment of obstructive sleep apnea. Clinics in Chest Medicine 24 (2): 355-64.

Ferguson, K.A., K. Heighway, and R.R. Ruby. 2003. A randomized trial of laser-assisted uvulopalatoplasty in the treatment of mild obstructive sleep apnea. American Journal of Respiratory and Critical Care Medicine 167 (1): 15-9.

Gula, L.J., A.D. Krahn, A. Skanes, K.A. Ferguson, C. George, R. Yee, and G.J. Klein. 2003. Heart rate variability in obstructive sleep apnea: a prospective study and frequency domain analysis. Annals of Noninvasive Electrocardiology 8 (2): 144-9.

FREEMAN, D.J.

GEORGE, C.F.

George, C.F., and C.D. Bayliff. 2003. Management of insomnia in patients with chronic obstructive pulmonary disease. Drugs 63 (4): 379-87.

GHENT, C.

Greig, P., L. Lilly, C. Scudamore, S. Erb, E. Yoshida, N. Kneteman, V. Bain, C. Ghent, P. Marotta, D. Grant, W. Wall, J. Tchervenkov, J. Barkun, A. Roy, D. Marleau, V. McAlister, and K. Peltekian. 2003. Early steroid withdrawal after liver transplantation: the Canadian tacrolimus versus microemulsion cyclosporin A trial: 1-year follow-up. Liver Transplantation 9 (6): 587-95.

GREGOR, J.C.

McGrath, J.S., T.P. Ponich, and J.C. Gregor. 2002. Screening for colorectal cancer: the cost to find an advanced adenoma. The American Journal of Gastroenterology 97 (11): 2902-7.

HARTH, M.

Harth, M. 2002. Provincial drug benefit programs. CMAJ 167 (1): 16.

HEGELE, R.A.

Al-Shali, K., J. Wang, F. Rosen, and R.A. Hegele. 2003. Ileal adenocarcinoma in a mild phenotype of abetalipoproteinemia. Clinical Genetics 63 (2): 135-8.

Argmann, C.A., C.G. Sawyez, C.J. McNeil, R.A. Hegele, and M.W. Huff. 2003. Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology 23 (3): 475-82.

Bjerregaard, P., E. Dewailly, T.K. Young, C. Blanchet, R.A. Hegele, S.E. Ebbesson, P.M. Risica, and G. Mulvad. 2003. Blood pressure among the Inuit (Eskimo) populations in the Arctic. Scandinavian Journal of Public Health 31 (2): 92-9.

Burnett, J.R., J. Shan, B.A. Miskie, A.J. Whitfield, J. Yuan, K. Tran, C.J. McKnight, R.A. Hegele, and Z. Yao. 2003. A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia. The Journal of Biological Chemistry 278 (15): 13442-52.

Cao, H., and R.A. Hegele. 2003. DNA polymorphism and mutations in CPN1, including the genomic basis of carboxypeptidase N deficiency. Journal of Human Genetics 48 (1): 20-2.

Cao, H., and R.A. Hegele. 2002. DNA polymorphisms in ITPA including basis of inosine triphosphatase deficiency. Journal of Human Genetics 47 (11): 620-2.

Cao, H., and R.A. Hegele. 2003. DNA polymorphisms of lipase related genes. Journal of Human Genetics 48 (8): 443-6.

Cao, H., and R.A. Hegele. 2002. Identification of single-nucleotide polymorphisms in the human LPIN1 gene. Journal of Human Genetics 47 (7): 370-2.

Cao, H., and R.A. Hegele. 2003. LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090). Journal of Human Genetics 48 (5): 271-4.

Cao, H., B.A. Miskie, and R.A. Hegele. 2002. Functional promoter polymorphism in SREBP cleavage-activating protein (SCAP). Journal of Human Genetics 47 (9): 492-6.

Cao, H., S. Shorey, J. Robinson, D.L. Metzger, L. Stewart, E. Cummings, and R.A. Hegele. 2002. GCK and HNF1A mutations in Canadian families with maturity onset diabetes of the young (MODY). Human Mutation 20 (6): 478-9.

Carpentier, A., B. Zinman, N. Leung, A. Giacca, A.J. Hanley, S.B. Harris, R.A. Hegele, and G.F. Lewis. 2003. Free fatty acid-mediated impairment of glucose-stimulated insulin secretion in nondiabetic Oji-Cree individuals from the Sandy Lake community of Ontario, Canada: a population at very high risk for developing type 2 diabetes. Diabetes 52 (6): 1485-95.

Connelly, P.W., A.J. Hanley, S.B. Harris, R.A. Hegele, and B. Zinman. 2003. Relation of waist circumference and glycemic status to C-reactive protein in the Sandy Lake Oji-Cree. International Journal of Obesity and Related Metabolic Disorders 27 (3): 347-54.

DeVries, M.E., H. Cao, J. Wang, L. Xu, A.A. Kelvin, L. Ran, L.A. Chau, J. Madrenas, R.A. Hegele, and D.J. Kelvin. 2003. Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. The Journal of Biological Chemistry 278 (14): 11985-94.

Hegele, R.A., H. Cao, C. Frankowski, S.T. Mathews, and T. Leff. 2002. PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy. Diabetes 51 (12): 3586-90.

Hegele, R.A., M. Eliasziw, and M. De Angelis. 2003. Sex, diabetes, and stroke after carotid endarterectomy. Diabetes Care 26 (5): 1641.

Hegele, R.A., B. Zinman, A.J. Hanley, S.B. Harris, P.H. Barrett, and H. Cao. 2003. Genes, environment and Oji-Cree type 2 diabetes. Clinical Biochemistry 36 (3): 163-70.

Keyhan, G., J. Rosset, J. Wang, D. Miller, R. McManus, and R.A. Hegele. 2002. Gene-drug interaction: additive influence of mutant APOA1 and testosterone on plasma HDL-cholesterol. Clinical Biochemistry 35 (5): 341-6.

Mok, A., H. Cao, and R.A. Hegele. 2003. Genomic basis of mucopolysaccharidosis type IIID (MIM 252940) revealed by sequencing of GNS encoding N-acetylglucosamine-6-sulfatase. Genomics 81 (1): 1-5.

Mymin, D., J. Wang, J. Frohlich, and R.A. Hegele. 2003. Image in cardiovascular medicine. Aortic xanthomatosis with coronary ostial occlusion in a child homozygous for a nonsense mutation in ABCG8. Circulation 107 (5): 791.

Prasad, G.V., D. Pinnaduwage, R.K. Parkes, J. Midgley, J.W. Balfe, R.A. Hegele, S.B. Bull, E.H. Cole, and A.G. Logan. 2003. Angiotensinogen M235T genotype predicts progression in chronic renal allograft dysfunction. Transplantation 75 (2): 209-16.

Rocnik, E.F., E. van der Veer, H. Cao, R.A. Hegele, and J.G. Pickering. 2002. Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells. The Journal of Biological Chemistry 277 (41): 38571-8.

Spence, J.D., M.R. Ban, and R.A. Hegele. 2003. Lipoprotein lipase (LPL) gene variation and progression of carotid artery plaque. Stroke 34 (5): 1176-80.

Vukmirica, J., K. Tran, X. Liang, J. Shan, J. Yuan, B.A. Miskie, R.A. Hegele, M.D. Resh, and Z. Yao. 2003. Assembly and secretion of very low density lipoproteins containing apolipoprotein B48 in transfected McA-RH7777 cells. Lack of evidence that palmitoylation of apolipoprotein B48 is required for lipoprotein secretion. The Journal of Biological Chemistry 278 (16): 14153-61.

Wang, J., and R.A. Hegele. 2003. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH). Human Genetics 112 (4): 404-8.

Wang, J., X.Y. Wen, A.K. Stewart, and R.A. Hegele. 2002. Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 ( PSPLA1). Journal of Human Genetics 47 (11): 611-3.

Wen, X.Y., R.A. Hegele, J. Wang, D.Y. Wang, J. Cheung, M. Wilson, M. Yahyapour, Y. Bai, L. Zhuang, J. Skaug, T.K. Young, P.W. Connelly, B.F. Koop, L.C. Tsui, and A.K. Stewart. 2003. Identification of a novel lipase gene mutated in lpd mice with hypertriglyceridemia and associated with dyslipidemia in humans. Human Molecular Genetics 12 (10): 1131-43.

HILL, D.J.

Srinivasan, M., S.G. Laychock, D.J. Hill, and M.S. Patel. 2003. Neonatal nutrition: metabolic programming of pancreatic islets and obesity. Experimental Biology and Medicine (Maywood, N.J.) 228 (1): 15-23.

HOLLOMBY, D.J.

Khakhar, A.K., V.B. Shahinian, A.A. House, N. Muirhead, D.J. Hollomby, S.H. Leckie, V.C. McAlister, J.L. Chin, A.M. Jevnikar, and P.P. Luke. 2003. The impact of allograft nephrectomy on percent panel reactive antibody and clinical outcome. Ransplantation Proceedings 35 (2): 862-3.

Luke, P.P., V.C. McAlister, A.M. Jevnikar, A.A. House, N. Muirhead, J. Cross, D. Hollomby, and J.L. Chin. 2003. Use of a pelvic kidney for living transplantation: case report and review of the literature. American Journal of Transplantation 3 (2): 235-8.

McLaughlin, K., C. Wu, G. Fick, N. Muirhead, D. Hollomby, and A. Jevnikar. 2002. Cytomegalovirus seromismatching increases the risk of acute renal allograft rejection. Transplantation 74 (6): 813-6.

Shahinian, V.B., N. Muirhead, A.M. Jevnikar, S.H. Leckie, A.K. Khakhar, P.P. Luke, K.S. Rizkalla, D.J. Hollomby, and A.A. House. 2003. Epstein-Barr virus seronegativity is a risk factor for late-onset posttransplant lymphoroliferative disorder in adult renal allograft recipients. Transplantation 75 (6): 851-6.

HOUSE, A.

Edwards, C., A. House, V. Shahinian, and G. Knoll. 2002. Sirolimus-based immunosuppression for transplant-associated thrombotic microangiopathy. Nephrology, Dialysis, Transplantation 17 (8): 1524-6.

HOWSON-JAN, K.

Couban, S., D.R. Simpson, M.J. Barnett, C. Bredeson, L. Hubesch, K. Howson-Jan, T.B. Shore, I.R. Walker, P. Browett, H.A. Messner, T. Panzarella, and J.H. Lipton. 2002. A randomized multicenter comparison of bone marrow and peripheral blood in recipients of matched sibling allogeneic transplants for myeloid malignancies. Blood 100 (5): 1525-31.

HUFF, M.W.

Borradaile, N.M., L.E. de Dreu, P.H. Barrett, C.D. Behrsin, and M.W. Huff. 2003. Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation. Biochemistry 42 (5): 1283-91.

Borradaile, N.M., L.E. de Dreu, P.H. Barrett, and M.W. Huff. 2002. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. Journal of Lipid Research 43 (9): 1544-54.

Borradaile, N.M., L.E. de Dreu, L.J. Wilcox, J.Y. Edwards, and M.W. Huff. 2002. Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms. The Biochemical Journal 366 (Pt 2): 531-9.

Hegele, R.A., M.E. Kraw, M.R. Ban, B.A. Miskie, M.W. Huff, and H. Cao. 2003. Elevated serum C-reactive protein and free fatty acids among nondiabetic carriers of missense mutations in the gene encoding lamin A/C (LMNA) with partial lipodystrophy. Arteriosclerosis, Thrombosis, and Vascular Biology 23 (1): 111-6.

Huff, M.W. 2003. Dietary cholesterol, cholesterol absorption, postprandial lipemia and atherosclerosis. The Canadian Journal of Clinical Pharmacology 10 Suppl A: 26A-32A.

Huff, M.W., D.E. Telford, J.Y. Edwards, J.R. Burnett, P.H. Barrett, S.R. Rapp, N. Napawan, and B.T. Keller. 2002. Inhibition of the apical sodium-dependent bile acid transporter reduces LDL cholesterol and apoB by enhanced plasma clearance of LDL apoB. Arteriosclerosis, Thrombosis, and Vascular Biology 22 (11): 1884-91.

Telford, D.E., J.Y. Edwards, S.M. Lipson, B. Sutherland, P.H. Barrett, J.R. Burnett, E.S. Krul, B.T. Keller, and M.W. Huff. 2003. Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB. Journal of Lipid Research 44 (5): 943-52.

HUSSAIN, Z.

John, M.A., C. Pletch, and Z. Hussain. 2002. In vitro activity of quinupristin/dalfopristin, linezolid, telithromycin and comparator antimicrobial agents against 13 species of coagulase-negative staphylococci. The Journal of Antimicrobial Chemotherapy 50 (6): 933-8.

Massey, V., D.B. Gregson, A.H. Chagla, M. Storey, M.A. John, and Z. Hussain. 2003. Clinical usefulness of components of the Triage immunoassay, enzyme immunoassay for toxins A and B, and cytotoxin B tissue culture assay for the diagnosis of Clostridium difficile diarrhea. American Journal of Clinical Pathology 119 (1): 45-9.

JEVNIKAR, A.M.

Hall, A.V., and A.M. Jevnikar. 2003. Significance of endothelial cell survival programs for renal transplantation. American Journal of Kidney Diseases 41 (6): 1140-54.

Min, W.P., D. Zhou, T.E. Ichim, G.H. Strejan, X. Xia, J. Yang, X. Huang, B. Garcia, D. White, P. Dutartre, A.M. Jevnikar, and R. Zhong. 2003. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. Journal of Immunology 170 (3): 1304-12.

Min, W.P., D. Zhou, T.E. Ichim, X. Xia, X. Zhang, J. Yang, X. Huang, B. Garcia, P. Dutartre, A.M. Jevnikar, G.H. Strejan, and R. Zhong. 2003. Synergistic tolerance induced by LF15-0195 and anti-CD45RB monoclonal antibody through suppressive dendritic cells. Transplantation 75 (8): 1160-5.

JOHN, M.

Ralph, E.D., M. John, M.J. Rieder, and A.M. Bombassaro. 2003. Serum sickness-like reaction possibly associated with meropenem use. Clinical Infectious Diseases 36 (11): E149-51.

KHALIL, W.

KLEIN, G.J.

Chauhan, V.S., A.D. Krahn, B.D. Walker, G.J. Klein, A.C. Skanes, and R. Yee. 2002. Sex differences in QTc interval and QT dispersion: dynamics during exercise and recovery in healthy subjects. The American Heart Journal 144 (5): 858-64.

Exner, D.V., and G.J. Klein. 2003. Do we need a randomized trial of defibrillator therapy in every subset of patients with increased risk of sudden death? Journal of Cardiovascular Electrophysiology 14 (6): 574-7.

Krahn, A., G. Klein, A.C. Skanes, and R. Yee. 2002. Amiodarone: pearl or peril? European Heart Journal 23 (13): 1001-2.

Krahn, A.D., G.J. Klein, R. Yee, and A.C. Skanes. 2003. Use of the implantable loop recorder in patients with unexplained syncope. Minerva Cardioangiologica 51 (1): 21-7.

Lee, J.K., G.J. Klein, A.D. Krahn, R. Yee, K. Zarnke, C. Simpson, and A. Skanes. 2003. Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results. Cardiac Electrophysiology Review 7 (2): 178-84.

LeLorier, P., and G. Klein. 2002. Prevention and management of postoperative atrial fibrillation. Current Problems in Cardiology 27 (9): 367-403.

LeLorier, P., A.D. Krahn, G.J. Klein, R. Yee, and A.C. Skanes. 2002. Comparison of patients with syncope with left ventricular dysfunction and negative electrophysiologic testing to cardiac arrest survivors and patients with syncope and preserved left ventricular function and impact of an implantable defibrillator. The American Journal of Cardiology 90 (1): 77-9.

Skanes, A.C., G.J. Klein, A.D. Krahn, and R. Yee. 2003. Advances in energy delivery. Coronary Artery Disease 14 (1): 15-23.

Skanes, A.C., R. Yee, A.D. Krahn, and G.J. Klein. 2002. Cryoablation of atrial arrhythmias. Cardiac Electrophysiology Review 6 (4): 383-8.

Todd, D.M., G.J. Klein, A.D. Krahn, A.C. Skanes, and R. Yee. 2003. Asymptomatic Wolff-Parkinson-White syndrome: is it time to revisit guidelines? Journal of the American College of Cardiology 41 (2): 245-8.

Walker, B.D., A.D. Krahn, G.J. Klein, A.C. Skanes, J. Wang, R.A. Hegele, and R. Yee. 2003. Congenital and acquired long QT syndromes. The Canadian Journal of Cardiology 19 (1): 76-87.

KOVAKS, M.J.

Anderson, D.R., M.J. Kovacs, G. Kovacs, I. Stiell, M. Mitchell, V. Khoury, J. Dryer, J. Ward, and P.S. Wells. 2003. Combined use of clinical assessment and d-dimer to improve the management of patients presenting to the emergency department with suspected deep vein thrombosis (the EDITED Study). Journal of Thrombosis and Haemostasis 1 (4): 645-51.

Kovacs, M.J., M. Rodger, D.R. Anderson, B. Morrow, G. Kells, J. Kovacs, E. Boyle, and P.S. Wells. 2003. Comparison of 10-mg and 5-mg warfarin initiation nomograms together with low-molecular-weight heparin for outpatient treatment of acute venous thromboembolism. A randomized, double-blind, controlled trial. Annals of Internal Medicine 138 (9): 714-9.

Kuruvilla, J., P.S. Wells, B. Morrow, K. MacKinnon, M. Keeney, and M.J. Kovacs. 2003. Prospective assessment of the natural history of positive D-dimer results in persons with acute venous thromboembolism (DVT or PE). Thrombosis and Haemostasis 89 (2): 284-7.

Payne, S.M., and M.J. Kovacs. 2003. Cutaneous dalteparin reactions associated with antibodies of heparin-induced thrombocytopenia. The Annals of Pharmacotherapy 37 (5): 655-8.

Wells, T., and M.J. Kovacs. 2003. Autoimmune thrombocytopenia due to chronic lymphocytic leukemia treated with fludarabine. The Annals of Pharmacotherapy 37 (5): 671-4.

KRAHN, A.D.

Assar, M.D., A.D. Krahn, R. Yee, and A.C. Skanes. 2003. Transition from narrow to wide complex tachycardia: connection or coincidence? Pacing and Clinical Electrophysiology 26 (1 Pt 1): 99-100.

Deschenes, D., S. Acharfi, V. Pouliot, R. Hegele, A. Krahn, P. Daleau, and M. Chahine. 2003. Biophysical characteristics of a new mutation on the KCNQ1 potassium channel (L251P) causing long QT syndrome. Canadian Journal of Physiology and Pharmacology 81 (2): 129-34.

Krahn, A., G. Klein, A.C. Skanes, and R. Yee. 2002. Amiodarone: pearl or peril? European Heart Journal 23 (13): 1001-2.

Krahn, A.D., G.J. Klein, R. Yee, and A.C. Skanes. 2003. Use of the implantable loop recorder in patients with unexplained syncope. Minerva Cardioangiologica 51 (1): 21-7.

Skanes, A.C., G.J. Klein, A.D. Krahn, and R. Yee. 2003. Advances in energy delivery. Coronary Artery Disease 14 (1): 15-23.

Skanes, A.C., R. Yee, A.D. Krahn, and G.J. Klein. 2002. Cryoablation of atrial arrhythmias. Cardiac Electrophysiology Review 6 (4): 383-8.

Walker, B.D., A.D. Krahn, G.J. Klein, A.C. Skanes, J. Wang, R.A. Hegele, and R. Yee. 2003. Congenital and acquired long QT syndromes. The Canadian Journal of Cardiology 19 (1): 76-87.

Walker, B.D., A.D. Krahn, A.C. Skanes, and R. Yee. 2002. Syncope and polymorphic ventricular tachycardia. Pacing and Clinical Electrophysiology 25 (8): 1259-61.

LEWIS, J.F.

Bailey, T.C., C. Cavanagh, S. Mehta, J.F. Lewis, and R.A. Veldhuizen. 2002. Sepsis and hyperoxia effects on the pulmonary surfactant system in wild-type and iNOS knockout mice. The European Respiratory Journal 20 (1): 177-82.

Lewis, J.F., and A. Brackenbury. 2003. Role of exogenous surfactant in acute lung injury. Critical Care Medicine 31 (4 Suppl): S324-8.

Lewis, J.F., and R. Veldhuizen. 2003. The role of exogenous surfactant in the treatment of acute lung injury. Annual Review of Physiology 65: 613-42.

Rasaiah, V.P., J.L. Malloy, J.F. Lewis, and R.A. Veldhuizen. 2003. Early surfactant administration protects against lung dysfunction in a mouse model of ARDS. American Journal of Physiology: Lung Cellular and Molecular Physiology 284 (5): L783-90.

LINDSAY, R.M.

Garland, J.S., C. Kianfar, G. Nesrallah, P. Heidenheim, and R.M. Lindsay. 2002. Measurement of extravascular lung water in hemodialysis patients using blood ultrasound velocity and optical density dilution. ASAIO J 48 (4): 398-403.

Prakash, S., D. Reddan, A.P. Heidenheim, C. Kianfar, and R.M. Lindsay. 2002. Central, peripheral, and other blood volume changes during hemodialysis. ASAIO J 48 (4): 379-82.

MAHON, J.L.

Feeny, D., C. Blanchard, J.L. Mahon, R. Bourne, C. Rorabeck, L. Stitt, and S. Webster-Bogaert. 2003. Comparing community-preference-based and direct standard gamble utility scores: evidence from elective total hip arthroplasty. International Journal of Technology Assessment in Health Care 19 (2): 362-72.

Mahon, J.L., R.B. Bourne, C.H. Rorabeck, D.H. Feeny, L. Stitt, and S. Webster-Bogaert. 2002. Health-related quality of life and mobility of patients awaiting elective total hip arthroplasty: a prospective study. CMAJ 167 (10): 1115-21.

Qin, H.Y., J.L. Mahon, M.A. Atkinson, P. Chaturvedi, E. Lee-Chan, and B. Singh. 2003. Type 1 diabetes alters anti-hsp90 autoantibody isotype. Journal of Autoimmunity 20 (3): 237-45.

MAROTTA, P.J.

MARTIN, C.M.

MASSEL, D.R.

Little, S.H., and D.R. Massel. 2003. Antiplatelet and anticoagulation for patients with prosthetic heart valves. Cochrane Database of Systematic Reviews (4): CD003464.

Massel, D. 2003. Observer variability in ECG interpretation for thrombolysis eligibility: experience and context matter. Journal of Thrombosis and Haemostasis 15 (3): 131-40.

Massel, D. 2002. Planned angiography after percutaneous coronary intervention increased reinterventions but did not affect mortality or MI. ACP J Club 137 (2): 45.

Massel, D. 2003. Primary angioplasty or thrombolysis for acute myocardial infarction? Lancet 361 (9361): 967; author reply 967-8.

Massel, D., D. McCormack, J. Lewis, and J. Mahon. 2002. Research of the holiday kind. Stableford: equitable golf-scoring system or quality-of-life measure? CMAJ 167 (12): 1337-40.

MCCAULEY, W.

Rapport, D.J., J. Howard, R. Lannigan, and W. McCauley. 2003. Linking health and ecology in the medical curriculum. Environment International 29 (2-3): 353-8.

MCCORMACK, D.G.

Dukelow, A.M., S. Weicker, T.A. Karachi, H.M. Razavi, D.G. McCormack, M.G. Joseph, and S. Mehta. 2002. Effects of nebulized diethylenetetraamine-NONOate in a mouse model of acute Pseudomonas aeruginosa pneumonia. Chest 122 (6): 2127-36.

Yaghi, A., S. Mehta, and D.G. McCormack. 2002. Delayed rectifier potassium channels contribute to the depressed pulmonary artery contractility in pneumonia. Journal of Applied Physiology 93 (3): 957-65.

MCDONALD, J.W.

Alfadhli, A.A., J.W. McDonald, and B.G. Feagan. 2003. Methotrexate for induction of remission in refractory Crohn's disease. Cochrane Database of Systematic Reviews (1): CD003459.

Chande, N., J.W. McDonald, and J.K. MacDonald. 2003. Interventions for treating collagenous colitis. Cochrane Database of Systematic Reviews (3): CD003575.

McDonald, J.W. 2003. Balsalazide achieved symptomatic remission sooner than mesalamine for ulcerative colitis. ACP J Club 138 (3): 71.

MCDONALD, T.J.

Behme, M.T., J. Dupre, and T.J. McDonald. 2003. Glucagon-like peptide 1 improved glycemic control in type 1 diabetes. BMC Endocrine Disorders 3 (1): 3.

Daniel, E.E., M. Anvari, J.E. Fox-Threlkeld, and T.J. McDonald. 2002. Local, exendin-(9-39)-insensitive, site of action of GLP-1 in canine ileum. American Journal of Physiology. Gastrointestinal and Liver Physiology 283 (3): G595-602.

MEHTA, S.

Mehta, S. 2003. Sildenafil for pulmonary arterial hypertension: exciting, but protection required. Chest 123 (4): 989-92.

MOIST, L.

Hanson, G., and L. Moist. 2003. Acute renal failure in the ICU: assessing the utility of continuous renal replacement. Journal of Critical Care 18 (1): 48-51.

Hejaili, F.F., L.M. Moist, and W.F. Clark. 2003. Treatment of lupus nephritis. Drugs 63 (3): 257-74.

MUIRHEAD, N.

Curtis, B.M., B.J. Barret, K. Jindal, O. Djurdjev, A. Levin, P. Barre, K. Bernstein, P. Blake, E. Carlisle, P. Cartier, C. Clase, B. Culleton, C. Deziel, S. Donnelly, J. Ethier, A. Fine, G. Ganz, M. Goldstein, J. Kappel, G. Karr, S. Langlois, D. Mendelssohn, N. Muirhead, B. Murphy, G. Pylpchuk, and E. Toffelmire. 2002. Canadian survey of clinical status at dialysis initiation 1998-1999: a multicenter prospective survey. Clinical Nephrology 58 (4): 282-8.

NIELSON, W.R.

Nielson, W.R., M.P. Jensen, and R.D. Kerns. 2003. Initial development and validation of a multidimensional pain readiness to change questionnaire. The Journal of Pain 4 (3): 148-58.

PFLUGFELDER, P.

Ross, H., P. Hendry, A. Dipchand, N. Giannetti, G. Hirsch, D. Isaac, N. Singh, L. West, M. White, A. Ignaszewski, A.M. Chung, L. Straatman, D. Modry, W. Tymchak, J. Burton, W. Warnica, J.E. Azevedo, W. Kostuk, A. Menkis, P. Pflugfelder, M. Quantz, R. Davies, H. Haddad, R. Masters, R. Cusimano, D. Delgado, C. Feindel, V. Rao, M. Cantarovich, R. Cecere, M. Carrier, M. Pellerin, D. Doyle, M.H. LeBlanc, and J. Howlett. 2003. 2001 Canadian Cardiovascular Society Consensus Conference on cardiac transplantation. The Canadian Journal of Cardiology 19 (6): 620-54.

PONICH, T.P.

McGrath, J.S., T.P. Ponich, and J.C. Gregor. 2002. Screening for colorectal cancer: the cost to find an advanced adenoma. The American Journal of Gastroenterology 97 (11): 2902-7.

POPE, J.E.

Pope, J.E. 2003. Musculoskeletal involvement in scleroderma. Rheumatic Diseases Clinics of North America 29 (2): 391-408.

Pope, J.E. 2002. Scleroderma overlap syndromes. Current Opinion in Rheumatology 14 (6): 704-10.

Pope, J.E., M. Joneja, and P. Hong. 2002. Anti-androgen treatment of prostatic carcinoma may be a risk factor for development of rheumatoid arthritis. The Journal of Rheumatology 29 (11): 2459-62.

Pope, J.E., D.P. Tingey, J.M. Arnold, P. Hong, J.M. Ouimet, and A. Krizova. 2003. Are subjects satisfied with the informed consent process? A survey of research participants. The Journal of Rheumatology 30 (4): 815-24.

Thompson, A.E., and J.E. Pope. 2002. Increased prevalence of scleroderma in southwestern Ontario: a cluster analysis. The Journal of Rheumatology 29 (9): 1867-73.

RALPH, E.D.

Ralph, E.D., M. John, M.J. Rieder, and A.M. Bombassaro. 2003. Serum sickness-like reaction possibly associated with meropenem use. Clinical Infectious Diseases 36 (11): E149-51.

SKANES, A.C.

Assar, M.D., A.D. Krahn, R. Yee, and A.C. Skanes. 2003. Transition from narrow to wide complex tachycardia: connection or coincidence? Pacing and Clinical Electrophysiology 26 (1 Pt 1): 99-100.

Krahn, A., G. Klein, A.C. Skanes, and R. Yee. 2002. Amiodarone: pearl or peril? European Heart Journal 23 (13): 1001-2.

Krahn, A.D., G.J. Klein, R. Yee, and A.C. Skanes. 2003. Use of the implantable loop recorder in patients with unexplained syncope. Minerva Cardioangiologica 51 (1): 21-7.

Skanes, A.C., G.J. Klein, A.D. Krahn, and R. Yee. 2003. Advances in energy delivery. Coronary Artery Disease 14 (1): 15-23.

Skanes, A.C., R. Yee, A.D. Krahn, and G.J. Klein. 2002. Cryoablation of atrial arrhythmias. Cardiac Electrophysiology Review 6 (4): 383-8.

Walker, B.D., A.D. Krahn, G.J. Klein, A.C. Skanes, J. Wang, R.A. Hegele, and R. Yee. 2003. Congenital and acquired long QT syndromes. The Canadian Journal of Cardiology 19 (1): 76-87.

Walker, B.D., A.D. Krahn, A.C. Skanes, and R. Yee. 2002. Syncope and polymorphic ventricular tachycardia. Pacing and Clinical Electrophysiology 25 (8): 1259-61.

SUSKIN, N.

Arthur, H.M., T. Swabey, and N. Suskin. 2003. The Ontario Cardiac Rehabilitation Pilot Project-final report. Journal of Cardiopulmonary Rehabilitation 23 (3): 242-3.

Suskin, N., S. MacDonald, T. Swabey, H. Arthur, M.A. Vimr, and R. Tihaliani. 2003. Cardiac rehabilitation and secondary prevention services in Ontario: recommendations from a consensus panel. The Canadian Journal of Cardiology 19 (7): 833-8.

VELDHUIZEN, R.A.

Bailey, T.C., E.L. Martin, L. Zhao, and R.A. Veldhuizen. 2003. High oxygen concentrations predispose mouse lungs to the deleterious effects of high stretch ventilation. Journal of Applied Physiology 94 (3): 975-82.

Lewis, J.F., and R. Veldhuizen. 2003. The role of exogenous surfactant in the treatment of acute lung injury. Annual Review of Physiology 65: 613-42.

WELLS, J.L.

WISENBERG, G.

Thompson, K., R.T. Thompson, J. Sykes, and G. Wisenberg. 2003. Long-term magnetic resonance imaging/spectroscopy study of cariporide in a canine cardiac ischemia/reperfusion model. Journal of Cardiovascular Pharmacology 41 (4): 536-43.

Thompson, K., G. Wisenberg, J. Sykes, and R.T. Thompson. 2003. MRI/MRS evaluation of cariporide in a canine long-term model of reperfused ischemic insults. Magnetic resonance imaging/magnetic resonance spectroscopy. Journal of Magnetic Resonance Imaging 17 (1): 136-41.

Thompson, K., G. Wisenberg, J. Sykes, and R.T. Thompson. 2002. Similar long-term cardiovascular effects of propofol or isoflurane anesthesia during ischemia/ reperfusion in dogs. Canadian Journal of Anaesthesia 49 (9): 978-85.

XENOCOSTAS, A.

Xenocostas, A., J.L. Callum, A.S. Coovadia, and M.D. Reis. 2002. Prolonged in vitro hemolysis of EDTA-anticoagulated blood after a delayed hemolytic transfusion reaction. Transfusion 42 (8): 1086-8.

YEE, R.

Assar, M.D., A.D. Krahn, R. Yee, and A.C. Skanes. 2003. Transition from narrow to wide complex tachycardia: connection or coincidence? Pacing and Clinical Electrophysiology 26 (1 Pt 1): 99-100.

Krahn, A., G. Klein, A.C. Skanes, and R. Yee. 2002. Amiodarone: pearl or peril? European Heart Journal 23 (13): 1001-2.

Krahn, A.D., G.J. Klein, R. Yee, and A.C. Skanes. 2003. Use of the implantable loop recorder in patients with unexplained syncope. Minerva Cardioangiologica 51 (1): 21-7.

Skanes, A.C., G.J. Klein, A.D. Krahn, and R. Yee. 2003. Advances in energy delivery. Coronary Artery Disease 14 (1): 15-23.

Skanes, A.C., R. Yee, A.D. Krahn, and G.J. Klein. 2002. Cryoablation of atrial arrhythmias. Cardiac Electrophysiology Review 6 (4): 383-8.

Todd, D.M., and R. Yee. 2003. Lessons from the implantable atrial defibrillator. The American Heart Journal 145 (4): 569-70.

Walker, B.D., A.D. Krahn, G.J. Klein, A.C. Skanes, J. Wang, R.A. Hegele, and R. Yee. 2003. Congenital and acquired long QT syndromes. The Canadian Journal of Cardiology 19 (1): 76-87.

Walker, B.D., A.D. Krahn, A.C. Skanes, and R. Yee. 2002. Syncope and polymorphic ventricular tachycardia. Pacing and Clinical Electrophysiology 25 (8): 1259-61.

ZARNKE, K.B.