Leaders in Learning: Publications of Faculty & Staff


Microbiology & Immunology 2002-2003



BHATIA, M.

Bhatia, M. 2003. The ultimate source of human hematopoietic stem cells: thinking outside the marrow. Cloning Stem Cells 5 (1): 89-97.

Hess, D.A., K.D. Levac, F.N. Karanu, M. Rosu-Myles, M.J. White, L. Gallacher, B. Murdoch, M. Keeney, P. Ottowski, R. Foley, I. Chin-Yee, and M. Bhatia. 2002. Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor. Blood 100 (3): 869-78.

Jay, K.E., L. Gallacher, and M. Bhatia. 2002. Emergence of muscle and neural hematopoiesis in humans. Blood 100 (9): 3193-202.

Murdoch, B., K. Chadwick, M. Martin, F. Shojaei, K.V. Shah, L. Gallacher, R.T. Moon, and M. Bhatia. 2003. Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America 100 (6): 3422-7.

Rosu-Myles, M., and M. Bhatia. 2003. SDF-1 enhances the expansion and maintenance of highly purified human hematopoietic progenitors. The Hematology Journal 4 (2): 137-45.

Wilpshaar, J., M. Bhatia, H.H. Kanhai, R. Breese, D.K. Heilman, C.S. Johnson, J.H. Falkenburg, and E.F. Srour. 2002. Engraftment potential of human fetal hematopoietic cells in NOD/SCID mice is not restricted to mitotically quiescent cells. Blood 100 (1): 120-7.



CHAGLA, A.H.

Massey, V., D.B. Gregson, A.H. Chagla, M. Storey, M.A. John, and Z. Hussain. 2003. Clinical usefulness of components of the Triage immunoassay, enzyme immunoassay for toxins A and B, and cytotoxin B tissue culture assay for the diagnosis of Clostridium difficile diarrhea. American Journal of Clinical Pathology 119 (1): 45-9.



CHAN, B.M.

Leabu, M., M.E. Hinescu, S. Uniyal, and B.M. Chan. 2003. Cell death in cell culture frame by frame. Journal of Cellular and Molecular Medicine 7 (2): 192-3.



CREUZENET, C.

Creuzenet, C., R.V. Urbanic, and J.S. Lam. 2002. Structure-function studies of two novel UDP-GlcNAc C6 dehydratases/C4 reductases. Variation from the SYK dogma. The Journal of Biological Chemistry 277 (30): 26769-78.



DEKABAN, G.A.

Manchanda, T., D. Schiedel, D. Fischer, G.A. Dekaban, and M.J. Rieder. 2002. Adverse drug reactions to protease inhibitors. The Canadian Journal of Clinical Pharmacology 9 (3): 137-46.

Weaver, L.C., D.R. Marsh, D. Gris, S.O. Meakin, and G.A. Dekaban. 2002. Central mechanisms for autonomic dysreflexia after spinal cord injury. Progress in Brain Research 137: 83-95.



DELOVITCH, T.L.

Arreaza, G., K. Salojin, W. Yang, J. Zhang, B. Gill, Q.S. Mi, J.X. Gao, C. Meagher, M. Cameron, and T.L. Delovitch. 2003. Deficient activation and resistance to activation-induced apoptosis of CD8+ T cells is associated with defective peripheral tolerance in nonobese diabetic mice. Clinical Immunology 107 (2): 103-15.

Meagher, C., S. Sharif, S. Hussain, M.J. Cameron, G.A. Arreaza, and T.L. Delovitch. 2003. Cytokines and chemokines in the pathogenesis of murine type 1 diabetes. Advances in Experimental Medicine and Biology 520: 133-58.

Wilson, S.B., and T.L. Delovitch. 2003. Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity. Nature Reviews. Immunology 3 (3): 211-22.



FLINTOFF, W.F.

Sadlish, H., F.M. Williams, and W.F. Flintoff. 2002. Functional role of arginine 373 in substrate translocation by the reduced folate carrier. The Journal of Biological Chemistry 277 (44): 42105-12.



HUSSAIN, Z.

John, M.A., C. Pletch, and Z. Hussain. 2002. In vitro activity of quinupristin/dalfopristin, linezolid, telithromycin and comparator antimicrobial agents against 13 species of coagulase-negative staphylococci. The Journal of Antimicrobial Chemotherapy 50 (6): 933-8.

Massey, V., D.B. Gregson, A.H. Chagla, M. Storey, M.A. John, and Z. Hussain. 2003. Clinical usefulness of components of the Triage immunoassay, enzyme immunoassay for toxins A and B, and cytotoxin B tissue culture assay for the diagnosis of Clostridium difficile diarrhea. American Journal of Clinical Pathology 119 (1): 45-9.



JASS, J.

Jass, J., T. Tjarnhage, and G. Puu. 2003. Atomic force microscopy imaging of liposomes. Methods in Enzymology 367: 199-213.



JEVNIKAR, A.M.

Min, W.P., D. Zhou, T.E. Ichim, G.H. Strejan, X. Xia, J. Yang, X. Huang, B. Garcia, D. White, P. Dutartre, A.M. Jevnikar, and R. Zhong. 2003. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. Journal of Immunology 170 (3): 1304-12.

Min, W.P., D. Zhou, T.E. Ichim, X. Xia, X. Zhang, J. Yang, X. Huang, B. Garcia, P. Dutartre, A.M. Jevnikar, G.H. Strejan, and R. Zhong. 2003. Synergistic tolerance induced by LF15-0195 and anti-CD45RB monoclonal antibody through suppressive dendritic cells. Transplantation 75 (8): 1160-5.



JOHN, M.A.

John, M.A., C. Pletch, and Z. Hussain. 2002. In vitro activity of quinupristin/dalfopristin, linezolid, telithromycin and comparator antimicrobial agents against 13 species of coagulase-negative staphylococci. The Journal of Antimicrobial Chemotherapy 50 (6): 933-8.

Massey, V., D.B. Gregson, A.H. Chagla, M. Storey, M.A. John, and Z. Hussain. 2003. Clinical usefulness of components of the Triage immunoassay, enzyme immunoassay for toxins A and B, and cytotoxin B tissue culture assay for the diagnosis of Clostridium difficile diarrhea. American Journal of Clinical Pathology 119 (1): 45-9.



KELVIN, D.J.

Cameron, M.J., and D.J. Kelvin. 2003. Cytokines and chemokines--their receptors and their genes: an overview. Advances in Experimental Medicine and Biology 520: 8-32.

DeVries, M.E., H. Cao, J. Wang, L. Xu, A.A. Kelvin, L. Ran, L.A. Chau, J. Madrenas, R.A. Hegele, and D.J. Kelvin. 2003. Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. The Journal of Biological Chemistry 278 (14): 11985-94.

DeVries, M.E., K.A. Hosiawa, C.M. Cameron, S.E. Bosinger, D. Persad, A.A. Kelvin, J.C. Coombs, H. Wang, R. Zhong, M.J. Cameron, and D.J. Kelvin. 2003. The role of chemokines and chemokine receptors in alloantigen-independent and alloantigen-dependent transplantation injury. Seminars in Immunology 15 (1): 33-48.

Wang, H., K.A. Hosiawa, B. Garcia, J.B. Shum, P. Dutartre, D.J. Kelvin, and R. Zhong. 2003. Attenuation of acute xenograft rejection by short-term treatment with LF15-0195 and monoclonal antibody against CD45RB in a rat-to-mouse cardiac transplantation model. Transplantation 75 (9): 1475-81.



LUCAS, A.

Dai, E., H. Guan, L. Liu, S. Little, G. McFadden, S. Vaziri, H. Cao, I.A. Ivanova, L. Bocksch, and A. Lucas. 2003. Serp-1, a viral anti-inflammatory serpin, regulates cellular serine proteinase and serpin responses to vascular injury. The Journal of Biological Chemistry 278 (20): 18563-72.

Seet, B.T., J.B. Johnston, C.R. Brunetti, J.W. Barrett, H. Everett, C. Cameron, J. Sypula, S.H. Nazarian, A. Lucas, and G. McFadden. 2003. Poxviruses and immune evasion. Annual Review of Immunology 21: 377-423.



MADRENAS, J.

DeVries, M.E., H. Cao, J. Wang, L. Xu, A.A. Kelvin, L. Ran, L.A. Chau, J. Madrenas, R.A. Hegele, and D.J. Kelvin. 2003. Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus. The Journal of Biological Chemistry 278 (14): 11985-94.

Madrenas, J. 2003. A SLAT in the Th2 signalosome. Immunity 18 (4): 459-61.

Puig-Kroger, A., O. Muniz-Pello, R. Selgas, G. Criado, M.A. Bajo, J.A. Sanchez-Tomero, V. Alvarez, G. del Peso, P. Sanchez-Mateos, C. Holmes, D. Faict, M. Lopez-Cabrera, J. Madrenas, and A.L. Corbi. 2003. Peritoneal dialysis solutions inhibit the differentiation and maturation of human monocyte-derived dendritic cells: effect of lactate and glucose-degradation products. Journal of Leukocyte Biology 73 (4): 482-92.

Tomas, E.M., T.A. Chau, and J. Madrenas. 2002. Clustering of a lipid-raft associated pool of ERM proteins at the immunological synapse upon T cell receptor or CD28 ligation. Immunology Letters 83 (2): 143-147.



MCCORMICK, J.K.

Beres, S.B., G.L. Sylva, K.D. Barbian, B. Lei, J.S. Hoff, N.D. Mammarella, M.Y. Liu, J.C. Smoot, S.F. Porcella, L.D. Parkins, D.S. Campbell, T.M. Smith, J.K. McCormick, D.Y. Leung, P.M. Schlievert, and J.M. Musser. 2002. Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence. Proceedings of the National Academy of Sciences of the United States of America 99 (15): 10078-83.

Burton, J.P., J.K. McCormick, P.A. Cadieux, and G. Reid. 2003. Digoxigenin-labelled peptide nucleic acid to detect lactobacilli PCR amplicons immobilized on membranes from denaturing gradient gel electrophoresis. Letters in Applied Microbiology 36 (3): 145-9.

McCormick, J.K., G.A. Bohach, and P.M. Schlievert. 2003. Pyrogenic, lethal, and emetic properties of superantigens in rabbits and primates. Methods in Molecular Biology 214: 245-53.

McCormick, J.K., and P.M. Schlievert. 2003. Expression, purification, and detection of novel streptococcal superantigens. Methods in Molecular Biology 214: 33-43.

Reid, G., and J.K. McCormick. 2002. Time for probiotics. The Lancet Infectious Diseases 2 (8): 459.

Smoot, L.M., J.K. McCormick, J.C. Smoot, N.P. Hoe, I. Strickland, R.L. Cole, K.D. Barbian, C.A. Earhart, D.H. Ohlendorf, L.G. Veasy, H.R. Hill, D.Y. Leung, P.M. Schlievert, and J.M. Musser. 2002. Characterization of two novel pyrogenic toxin superantigens made by an acute rheumatic fever clone of Streptococcus pyogenes associated with multiple disease outbreaks. Infection and Immunity 70 (12): 7095-104.

Tripp, T.J., J.K. McCormick, J.M. Webb, and P.M. Schlievert. 2003. The zinc-dependent major histocompatibility complex class II binding site of streptococcal pyrogenic exotoxin C is critical for maximal superantigen function and toxic activity. Infection and Immunity 71 (3): 1548-50.



MCFADDEN, G.

Brunetti, C.R., M. Paulose-Murphy, R. Singh, J. Qin, J.W. Barrett, A. Tardivel, P. Schneider, K. Essani, and G. McFadden. 2003. A secreted high-affinity inhibitor of human TNF from Tanapox virus. Proceedings of the National Academy of Sciences of the United States of America 100 (8): 4831-6.

Chang, C.S., and G. McFadden. 2002. Characterization of a monoclonal antibody specific for a novel primate cell surface marker with distinct biochemical properties on human erythroleukemia and myeloid cell lines. Hybridoma and Hybridomics 21 (4): 271-80.

Chang, C.S., and G. McFadden. 2002. Characterization of a pan-species reactive monoclonal antibody specific for a cell surface epitope which could serve as a marker for human monocytic and megakaryocytic differentiation. Hybridoma and Hybridomics 21 (6): 445-56.

Dai, E., H. Guan, L. Liu, S. Little, G. McFadden, S. Vaziri, H. Cao, I.A. Ivanova, L. Bocksch, and A. Lucas. 2003. Serp-1, a viral anti-inflammatory serpin, regulates cellular serine proteinase and serpin responses to vascular injury. The Journal of Biological Chemistry 278 (20): 18563-72.

Everett, H., M. Barry, X. Sun, S.F. Lee, C. Frantz, L.G. Berthiaume, G. McFadden, and R.C. Bleackley. 2002. The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore. The Journal of Experimental Medicine 196 (9): 1127-39.

Johnston, J.B., J.W. Barrett, W. Chang, C.S. Chung, W. Zeng, J. Masters, M. Mann, F. Wang, J. Cao, and G. McFadden. 2003. Role of the serine-threonine kinase PAK-1 in myxoma virus replication. Journal of Virology 77 (10): 5877-88.

Johnston, J.B., and G. McFadden. 2003. Poxvirus immunomodulatory strategies: current perspectives. Journal of Virology 77 (11): 6093-100.

Mansouri, M., E. Bartee, K. Gouveia, B.T. Hovey Nerenberg, J. Barrett, L. Thomas, G. Thomas, G. McFadden, and K. Fruh. 2003. The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4. Journal of Virology 77 (2): 1427-40.

Seet, B.T., J.B. Johnston, C.R. Brunetti, J.W. Barrett, H. Everett, C. Cameron, J. Sypula, S.H. Nazarian, A. Lucas, and G. McFadden. 2003. Poxviruses and immune evasion. Annual Review of Immunology 21: 377-423.



MIN, W.P.

Min, W.P., D. Zhou, T.E. Ichim, G.H. Strejan, X. Xia, J. Yang, X. Huang, B. Garcia, D. White, P. Dutartre, A.M. Jevnikar, and R. Zhong. 2003. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. Journal of Immunology 170 (3): 1304-12.

Min, W.P., D. Zhou, T.E. Ichim, X. Xia, X. Zhang, J. Yang, X. Huang, B. Garcia, P. Dutartre, A.M. Jevnikar, G.H. Strejan, and R. Zhong. 2003. Synergistic tolerance induced by LF15-0195 and anti-CD45RB monoclonal antibody through suppressive dendritic cells. Transplantation 75 (8): 1160-5.



O'CONNELL, P.J.

Yi, S., W.J. Hawthorne, A.M. Lehnert, H. Ha, J.K. Wong, N. van Rooijen, K. Davey, A.T. Patel, S.N. Walters, A. Chandra, and P.J. O'Connell. 2003. T cell-activated macrophages are capable of both recognition and rejection of pancreatic islet xenografts. Journal of Immunology 170 (5): 2750-8.

Yi, S., and P.J. O'Connell. 2002. IFN-gamma but not IL-4 is important for mouse CD4+ T cell-mediated macrophage activation following their exposure to pig cells in vitro. Xenotransplantation 9 (4): 268-76.



REID, G.

Bruce, A.W., and G. Reid. 2003. Probiotics and the urologist. The Canadian Journal of Urology 10 (2): 1785-9.

Burton, J.P., P.A. Cadieux, and G. Reid. 2003. Improved understanding of the bacterial vaginal microbiota of women before and after probiotic instillation. Applied and Environmental Microbiology 69 (1): 97-101.

Burton, J.P., J.L. Dixon, and G. Reid. 2003. Detection of Bifidobacterium species and Gardnerella vaginalis in the vagina using PCR and denaturing gradient gel electrophoresis (DGGE). International Journal of Gynaecology and Obstetrics 81 (1): 61-3.

Burton, J.P., J.K. McCormick, P.A. Cadieux, and G. Reid. 2003. Digoxigenin-labelled peptide nucleic acid to detect lactobacilli PCR amplicons immobilized on membranes from denaturing gradient gel electrophoresis. Letters in Applied Microbiology 36 (3): 145-9.

Burton, J.P., and G. Reid. 2002. Evaluation of the bacterial vaginal flora of 20 postmenopausal women by direct (Nugent score) and molecular (polymerase chain reaction and denaturing gradient gel electrophoresis) techniques. The Journal of Infectious Diseases 186 (12): 1770-80.

Reid, G. 2002. The potential role of probiotics in pediatric urology. The Journal of Urology 168 (4 Pt 1): 1512-7.

Reid, G. 2002. Safety of lactobacillus strains as probiotic agents. Clinical Infectious Diseases 35 (3): 349-50.

Reid, G., D. Charbonneau, J. Erb, B. Kochanowski, D. Beuerman, R. Poehner, and A.W. Bruce. 2003. Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo-controlled trial in 64 healthy women. FEMS Immunology and Medical Microbiology 35 (2): 131-4.

Reid, G., and J.K. McCormick. 2002. Time for probiotics. The Lancet Infectious Diseases 2 (8): 459.

Watterson, J.D., P.A. Cadieux, D.T. Beiko, A.J. Cook, J.P. Burton, R.R. Harbottle, C. Lee, E. Rowe, H. Sidhu, G. Reid, and J.D. Denstedt. 2003. Oxalate-degrading enzymes from Oxalobacter formigenes: a novel device coating to reduce urinary tract biomaterial-related encrustation. Journal of Endourology 17 (5): 269-74.



SINGH, B.

Mukherjee, R., P. Chaturvedi, B. Agrawal, and B. Singh. 2003. Regulation of type 1 diabetes by a self-MHC class II peptide: role of transforming growth factor beta (TGF-beta). Cellular and Molecular Biology 49 (2): 159-169.

Qin, H.Y., J.L. Mahon, M.A. Atkinson, P. Chaturvedi, E. Lee-Chan, and B. Singh. 2003. Type 1 diabetes alters anti-hsp90 autoantibody isotype. Journal of Autoimmunity 20 (3): 237-45.



STREJAN, G.H.

Min, W.P., D. Zhou, T.E. Ichim, G.H. Strejan, X. Xia, J. Yang, X. Huang, B. Garcia, D. White, P. Dutartre, A.M. Jevnikar, and R. Zhong. 2003. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. Journal of Immunology 170 (3): 1304-12.

Min, W.P., D. Zhou, T.E. Ichim, X. Xia, X. Zhang, J. Yang, X. Huang, B. Garcia, P. Dutartre, A.M. Jevnikar, G.H. Strejan, and R. Zhong. 2003. Synergistic tolerance induced by LF15-0195 and anti-CD45RB monoclonal antibody through suppressive dendritic cells. Transplantation 75 (8): 1160-5.



VALVANO, M.A.

Bittner, M., S. Saldias, C. Estevez, M. Zaldivar, C.L. Marolda, M.A. Valvano, and I. Contreras. 2002. O-antigen expression in Salmonella enterica serovar Typhi is regulated by nitrogen availability through RpoN-mediated transcriptional control of the rfaH gene. Microbiology 148 (Pt 12): 3789-99.

Fehlner-Gardiner, C.C., and M.A. Valvano. 2002. Cloning and characterization of the Burkholderia vietnamiensis norM gene encoding a multi-drug efflux protein. FEMS Microbiology Letters 215 (2): 279-83.

Lefebre, M.D., and M.A. Valvano. 2002. Construction and evaluation of plasmid vectors optimized for constitutive and regulated gene expression in Burkholderia cepacia complex isolates. Applied and Environmental Microbiology 68 (12): 5956-64.

Sajjan, U.S., H. Xie, M.D. Lefebre, M.A. Valvano, and J.F. Forstner. 2003. Identification and molecular analysis of cable pilus biosynthesis genes in Burkholderia cepacia. Microbiology 149 (Pt 4): 961-71.

Valvano, M.A. 2003. Export of O-specific lipopolysaccharide. Frontiers in Bioscience 8: s452-71.

Valvano, M.A., P. Messner, and P. Kosma. 2002. Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides. Microbiology 148 (Pt 7): 1979-89.