Zamir: Blood flow to the uterus
Mair Zamir, Professor Emeritus from the Department of Applied Mathematics at Western University studies the way fluids flow. Zamir came to Western in 1970. At the time, engaged in the field of aeronautics — which relates to the flow of air around an aircraft in flight. Almost immediately, with help from some brilliant minds in the Department of Biophysics at the time, he turned his attention to Medicine, specifically to the area of blood flow. Fast forward almost a half century, he is now helping clinicians understand the remarkable system of blood flow from mother to fetus.
We are never more vulnerable and reliant than when we are in our mother’s uterus. Understanding the processes that may cause a deficiency in blood supply to the uterus such as placental insufficiency or preeclampsia is critical to the survival, in many cases, of both mother and baby.
The normal mechanism for the control of blood supply within the body consists of adjusting the
Women’s bodies have adapted to this challenge by developing a complex system of spiral arteries that are unique to that part of the female vascular anatomy.
“In all my years working on
The rate at which blood flows in our arteries depends on the prevailing resistance to that flow. The longer
Disorders such as preeclampsia, where the spiral arteries stay wound until too late in the pregnancy, leave the baby with not enough blood supply to survive. Zamir’s work, in collaboration with his clinical colleagues, aims to unlock solutions to increase the delivery of healthy babies and the survival of their mothers. The analysis supporting their findings appear in the current issue of the journal Placenta.