Welcome to the Singh Lab

The University of Western Ontario
Schulich School of Medicine & Dentistry
Department of Microbiology & Immunology

Career and Research Profile

Dr. Singh is the inaugural Director of the Centre for Human Immunology (CHI) at the University of Western Ontario (UWO) and Professor in the Department of Microbiology and Immunology and Scientist at the Robarts Research Institute. From 2001-2009 he served as the founding Scientific Director of the Institute of Infection and Immunity, one of 13 Institutes of the Canadian Institutes of Health Research (CIHR), the main public funding body for health research in Canada. . He served as Professor and Chair of the Department of Microbiology and Immunology at the University of Western Ontario from 1992-2001 and from 1997-2001 was also the Deputy Director of the Robarts Research Institute. He was a faculty member in the Department of Immunology at the University of Alberta, Edmonton from 1977-1992.

His laboratory has done seminal work in the immunology of peptides. Well before the crystal structure of MHC molecules was elucidated his laboratory identified that peptides of 9-12 amino acids were required for priming and triggering of humoral and helper T cell-mediated immune responses. His laboratory first described that immunomodulation induced by microbial adjuvants such as CFA or BCG prevented autoimmune type 1 diabetes and its recurrence and regulatory CD4 T cells played an important role in this process. This work had a major impact in our understanding of the role of microbial agents and in the formulation of the Hygiene hypothesis for protective immunity. He has published over 200 articles in peer-reviewed journals.
Honours and Awards

Dr. Singh is recognized as a leader in the field of immunology of peptides and the regulation of autoimmune responses in type 1 diabetes. In recognition of his significant contributions, Dr. Singh has been the recipient of numerous awards including the Alberta Heritage Medical Scientist Award and the Award of Excellence of the Faculty of Medicine of University of Western Ontario. In 2000 he was the Banting and Best Memorial Lecturer at the 17th International Diabetes Federation Congress and in 2001 he was Bernhard Cinader Award Lecturer at the Canadian Society for Immunology. He was elected fellow of the Royal Society of Canada (FRSC) in 2004 and of the Canadian Academy of Health Sciences (FCAHS) in 2005. He has served as a member of peer review grant panels of the Juvenile Diabetes Foundation International, the Canadian Diabetes Association, CIHR and the National Institute of Health. In 2010 he received the John D. Reynolds award of the Canadian Society for Immunology for his contributions to Canadian immunology. 

Bhagirath Singh, Ph. D.

Dr. Bhagirath Singh
Director, Centre for Human Immunology
Professor, Department of Microbiology & Immunology
Scientist, Robarts Research Institute
University of Western Ontario
London, Ontario, Canada

Contact information:
Room 214, Siebens Drake Medical Research Institute
1400 Western Road
London, Ontario N6G 2V4
Tel. (Office): (519) 661-3228
Tel. (Laboratory): (519) 661-3483
Fax: (519) 661-3499
E-mail: bsingh@uwo.ca



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