Now would be a good time to obtain a focused history from your patient.  Questions should be based on the differential diagnosis of epistaxis. 

What is the differential diagnosis of Epistaxis?

Type

Causes

 

Local

  • Trauma (nasal fracture, septal perforation/hematoma)
  • Foreign body
  • Surgical procedures
  • URTI, Sinusitis, Atrophic rhinitis
  • Chemical irritants (i.e. cocaine)

Neoplasm

  • Benign (juvenile angiofibroma, polyps)
  • Malignant (squamous cell carcinoma)

Systemic

  • Atherosclerotic disease with hypertension
  • Hepatic disease (decrease in clotting factors)
  • Renal disease (elevated BUN causes decreased platelet adhesiveness)

 

Hematologic Disorders

  • Myeloma,
  • Leukemia, Lymphoma
  • Hemophilia
  • Anemia

Genetic

  • Hereditary hemorrhagic telangectasia (Osler-Weber-Rendu disease)

Drugs

  • NSAIDs
  • Aspirin
  • Warfarin

Idiopathic

 

Fig 2: Differential Diagnosis of epistaxis

Now you can direct your questioning based on your differential: