TEMPLATE

Leaders in Learning: Publications of Faculty & Staff

Physiology & Pharmacology 2004-2005

Babwah, A.V.

Dhami, G.K., A.V. Babwah, R. Sterne-Marr, and S.S. Ferguson. 2005. Phosphorylation-independent regulation of metacotropic glutamate receptor 1 signaling requires g protein-coupled receptor kinase 2 binding to the second intracellular loop. Journal of Biological Chemistry 67 (2): 24420-24427.

Bai, D.L.

Gong, X.G., A. Frandsen, W.Y. Lu, Y.D. Wan, R.L. Zabek, D.S. Pickering, and D.L. Bai. 2005. D-Aspartate and Nmda, but Not L-Aspartate, Block Ampa Receptors in Rat Hippocampal Neurons. British Journal of Pharmacology 145 (4): 449-459.

Kolaj, M., D.L. Bai, and L.P. Renaud. 2004. Gaba(B) Receptor Modulation of Rapid Inhibitory and Excitatory Neurotransmission From Subfornical Organ and Other Afferents to Median Preoptic Nucleus Neurons. Journal of Neurophysiology 92 (1): 111-122.

Roscoe, W., G.I.L. Veitch, X.Q. Gong, E. Pellegrino, D. Bai, E. Mclachlan, Q. Shao, G.M. Kidder, and D.W. Laird. 2005. Oculodentodigital Dysplasia-Causing Connexin43 Mutants Are Non-Functional and Exhibit Dominant Effects on Wild-Type Connexin43. Journal of Biological Chemistry 280 (12): 11458-11466.

Beier, F.

Wang, G.Y., and F. Beier. 2005. Rac1/Cdc42 and RhoA GTPases Antagonistically Regulate Chondrocyte Proliferation, Hypertrophy, and Apoptosis. Journal of Bone and Mineral Research 20 (6): 1022-1031.

Woods, A., C. James, T.M. Underhill, and F. Beier. 2004. Identification of the Putative Collagen X Gene From the Pufferfish Fugu Rubripes. Gene 342 (1): 77-83.

Woods, A., G.Y. Wang, and F. Beier. 2005. Rhoa/Rock Signaling Regulates Sox9 Expression and Actin Organization During Chondrogenesis. Journal of Biological Chemistry 280 (12): 11626-11634.

Bhattacharya, M.

Bhattacharya, M., A.V. Babwah, and S.S.G. Ferguson. 2004. Small Gtp-Binding Protein-Coupled Receptors. Biochemical Society Transactions 32: 1040-1044.

Bhattacharya, M., A.V. Babwah, C. Godin, P.H. Anborgh, L.B. Dale, M.O. Poulter, and S.S.G. Ferguson. 2004. Ral and Phospholipase D2-Dependent Pathway for Constitutive Metabotropic Glutamate Receptor Endocytosis. Journal of Neuroscience 24 (40): 8752-8761.

Chidiac, P.

Gan, X.H.T., V. Rajapurohitam, J.V. Haist, P. Chidiac, M.A. Cook, and M. Karmazyn. 2005. Inhibition of Phenylephrine-Induced Cardiomyocyte Hypertrophy by Activation of Multiple Adenosine Receptor Subtypes. Journal of Pharmacology and Experimental Therapeutics 312 (1): 27-34.

Hepler, J.R., W. Cladman, S. Ramineni, S. Hollinger, and P. Chidiac. 2005. Novel Activity of Rgs14 on Go Alpha and Gi Alpha Nucleotide Binding and Hydrolysis Distinct From Its Rgs Domain and Gdi Activity. Biochemistry 44 (14): 5495-5502.

Twiner, M.J., P. Chidiac, S.J. Dixon, and C.G. Trick. 2005. Extracellular Organic Compounds From the Ichthyotoxic Red Tide Alga Heterosigma Akashiwo Elevate Cytosolic Calcium and Induce Apoptosis in Sf9 Cells. Harmful Algae 4 (4): 789-800.

Cook, M.A.

Xia, Y., V. Rajapurohitam, M.A. Cook, and M. Karmazyn. 2004. Inhibition of Phenylephrine Induced Hypertrophy in Rat Neonatal Cardiomyocytes by the Mitochondrial K-Atp Channel Opener Diazoxide. Journal of Molecular and Cellular Cardiology 37 (5): 1063-1067.

Corneil, B.D.

Corneil, B.D., and R.A. Andersen. 2004. Dorsal Neck Muscle Vibration Induces Upward Shifts in the Endpoints of Memory-Guided Saccades in Monkeys. Journal of Neurophysiology 92 (1): 553-566.

D'Souza, S.J.

Chang, W.Y., D.M. Bryce, S.J.A. D'souza, and L. Dagnino. 2004. The Dp-1 Transcription Factor Is Required for Keratinocyte Growth and Epidermal Stratification. Journal of Biological Chemistry 279 (49): 51343-51353.

Ivanova, I.A., S.J. D'Souza, and L. Dagnino. 2005. Signalling in the Epidermis: The E2f Cell Cycle Regulatory Pathway In Epidermal Morphogenesis, Regeneration and Transformation. International Journal of Biological Science 1 (2): 87-95.

Martin-McCaffrey, L., F.S. Willard, A.J. Oliveira-Dos-Santos, D.R.C. Natale, B.E. Snow, R.J. Kimple, A. Pajak, A.J. Watson, L. Dagnino, J.M. Penninger, D.P. Siderovski, and S.J.A. D'souza. 2004. RGS14 Is a Mitotic Spindle Protein Essential From the First Division of the Mammalian Zygote. Developmental Cell 7 (5): 763-769.

Dagnino, L.

Voskas, D., N. Jones, P. Van Slyke, C. Sturk, W. Chang, A. Haninec, Y.Y. Babichev, J. Tran, Z. Master, S. Chen, N. Ward, M. Cruz, J. Jones, R.S. Kerbel, S. Jothy, L. Dagnino, J. Arbiser, G. Klement, and D.J. Dumont. 2005. A Cyclosporine-Sensitive Psoriasis-Like Disease Produced in Tie2 Transgenic Mice. American Journal of Pathology 166 (3): 843-855.

Dixon, S.J.

Best, K.A., M.E. Holmes, S.E. Samson, J. Mwanjewe, J.X. Wilson, S.J. Dixon, and A.K. Grover. 2005. Ascorbate Uptake in Pig Coronary Artery Endothelial Cells. Molecular and Cellular Biochemistry 271 (1-2): 43-49.

Dixon, S.J., R.G. Yu, N. Panupinthu, and J.X. Wilson. 2004. Activation of P2 Nucleotide Receptors Stimulates Acid Efflux From Astrocytes. Glia 47 (4): 367-376.

Komarova, S.V., A. Pereverzev, J.W. Shum, S.M. Sims, and S.J. Dixon. 2005. Convergent Signaling by Acidosis and Receptor Activator of Nf-Kappa B Ligand (Rankl) on the Calcium/Calcineurin/Nfat Pathway in Osteoclasts. Proceedings of the National Academy of Sciences of the United States of America 102 (7): 2643-2648.

Korcok, J., L.N. Raimundo, X.B. Du, S.M. Sims, and S.J. Dixon. 2005. P2y6 Nucleotide Receptors Activate Nf-Kappa B and Increase Survival of Osteoclasts. Journal of Biological Chemistry 280 (17): 16909-16915.

Poustie, M.W., J. Carran, K. Mceleney, S.J. Dixon, T.P. Anastassiades, and S.M. Bernier. 2004. N-Butyryl Glucosamine Increases Matrix Gene Expression by Chondrocytes. Journal of Pharmacology and Experimental Therapeutics 311 (2): 610-616.

Dupre, J.

Dupre, J., M.T. Behme, and T.J. Mcdonald. 2004. Exendin-4 Normalized Postcibal Glycemic Excursions in Type 1 Diabetes. Journal of Clinical Endocrinology and Metabolism 89 (7): 3469-3473.

Everling, S.

Koval, M.J., K.A. Ford, and S. Everling. 2004. Effect of Stimulus Probability on Anti-Saccade Error Rates. Experimental Brain Research 159 (2): 268-272.

Feng, Q.P.

McCarter, S.D., T.G. Akyea, X.G. Lu, A. Bihari, J.R. Scott, A. Badhwar, A.A. Dungey, K.A. Harris, Q.P. Feng, and R.F. Potter. 2004. Endogenous Heme Oxygenase Induction Is a Critical Mechanism Attenuating Apoptosis and Restoring Microvascular Perfusion Following Limb Ischemia/Reperfusion. Surgery 136 (1): 67-75.

Moe, G.W., J. Marin-Garcia, A. Konig, M. Goldenthal, X.R. Lu, and Q.P. Feng. 2004. In Vivo Tnf-Alpha Inhibition Ameliorates Cardiac Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Experimental Heart Failure. American Journal of Physiology-Heart and Circulatory Physiology 287 (4): H1813-H1820.

Peng, T.Q., X.R. Lu, and Q.P. Feng. 2005. Pivotal Role of Gp91(Phox)-Containing Nadh Oxidase in Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression. Circulation 111 (13): 1637-1644.

Rui, T., Q.P. Feng, M. Lei, T.Q. Peng, J.H. Zhang, M. Xu, E.D. Abel, A. Xenocostas, and P.R. Kvietys. 2005. Erythropoietin Prevents the Acute Myocardial Inflammatory Response Induced by Ischemia/Reperfusion Via Induction of Ap-1. Cardiovascular Research 65 (3): 719-727.

Tran, K.L., X.G. Lu, M. Lei, Q.P. Feng, and Q.Y. Wu. 2004. Upregulation of Corin Gene Expression in Hypertrophic Cardiomyocytes and Failing Myocardium. American Journal of Physiology-Heart and Circulatory Physiology 287 (4): H1625-H1631.

Wang, Y.X., B. Martin-Mcnulty, V. Da Cunha, J. Vincelette, X.G. Lu, Q.P. Feng, M. Halks-Miller, M. Mahmoudi, M. Schroeder, B. Subramanyam, J.L. Tseng, G.D. Deng, S. Schirm, A. Johns, K. Kauser, W.P. Dole, and D.R. Light. 2005. Fasudil, a Rho-Kinase Inhibitor, Attenuates Angiotensin Ii-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice by Inhibiting Apoptosis and Proteolysis. Circulation 111 (17): 2219-2226.

Ferguson, S.S.G.

Bhattacharya, M., A.V. Babwah, and S.S.G. Ferguson. 2004. Small Gtp-Binding Protein-Coupled Receptors. Biochemical Society Transactions 32: 1040-1044.

Ding, Q.M., R. Gros, J. Chorazyczewski, S.S.G. Ferguson, and R.D. Feldman. 2005. Isoform-Specific Regulation of Adenylyl Cyclase Function by Disruption of Membrane Trafficking. Molecular Pharmacology 67 (2): 564-571.

Hammond, J.R.

Archer, R.G.E., V. Pitelka, and J.R. Hammond. 2004. Nucleoside Transporter Subtype Expression and Function in Rat Skeletal Muscle Microvascular Endothelial Cells. British Journal of Pharmacology 143 (1): 202-214.

Stolk, M., E. Cooper, G. Vilk, D.W. Litchfield, and J.R. Hammond. 2005. Subtype-Specific Regulation of Equilibrative Nucleoside Transporters by Protein Kinase Ck2. Biochemical Journal 386: 281-289.

Henry, J.L.

Dableh, L.J., K. Yashpal, J. Rochford, and J.L. Henry. 2005. Antidepressant-Like Effects of Neurokinin Receptor Antagonists in the Forced Swim Test in the Rat. European Journal of Pharmacology 507 (1-3): 99-105.

Henry, J.L. 2004. Future Basic Science Directions Into Mechanisms of Neuropathic Pain. Journal of Orofacial Pain 18 (4): 306-310.

Hore, J.

Hore, J., and S. Watts. 2005. Timing Finger Opening in Overarm Throwing Based on a Spatial Representation of Hand Path. Journal of Neurophysiology 93 (6): 3189-3199.

Watts, S., I. Pessotto, and J. Hore. 2004. A Simple Rule for Controlling Overarm Throws to Different Targets. Experimental Brain Research 159 (3): 329-339.

Ivanova, I.A.

Jones, D.L

Jiang, M., A. Xu, D.L. Jones, and N. Narayanan. 2004. Coordinate Downregulation of Cam Kinase Ii and Phospholamban Accompanies Contractile Phenotype Transition in the Hyperthyroid Rabbit Soleus. American Journal of Physiology-Cell Physiology 287 (3): C622-C632.

Skanes, A.C., D.L. Jones, P. Teefy, C. Guiraudon, R. Yee, A.D. Krahn, and G.J. Klein. 2004. Safety and Feasibility of Cryothermal Ablation Within the Mid- and Distal Coronary Sinus. Journal of Cardiovascular Electrophysiology 15 (11): 1319-1323.

Karmazyn, M.

Fliegel, L., and M. Karmazyn. 2004. The Cardiac Na-H Exchanger: a Key Downstream Mediator for the Cellular Hypertrophic Effects of Paracrine, Autocrine and Hormonal Factors. Biochemistry and Cell Biology-Biochimie Et Biologie Cellulaire 82 (6): 626-635.

Javadov, S., C. Huang, L. Kirshenbaum, and M. Karmazyn. 2005. Nhe-1 Inhibition Improves Impaired Mitochondrial Permeability Transition and Respiratory Function During Postinfarction Remodelling in the Rat. Journal of Molecular and Cellular Cardiology 38 (1): 135-143.

Purdham, D.M., M.X. Zou, V. Rajapurohitam, and M. Karmazyn. 2004. Rat Heart Is a Site of Leptin Production and Action. American Journal of Physiology-Heart and Circulatory Physiology 287 (6): H2877-H2884.

Xia, Y., and M. Karmazyn. 2004. Obligatory Role for Endogenous Endothelin in Mediating the Hypertrophic Effects of Phenylephrine and Angiotensin Ii in Neonatal Rat Ventricular Myocytes: Evidence for Two Distinct Mechanisms for Endothelin Regulation. Journal of Pharmacology and Experimental Therapeutics 310 (1): 43-51.

Kidder, G.M.

Gittens, J.E.I., K.J. Barr, B.C. Vanderhyden, and G.M. Kidder. 2005. Interplay Between Paracrine Signaling and Gap Junctional Communication in Ovarian Follicles. Journal of Cell Science 118 (1): 113-122.

Jones, D.H., T.Y. Li, E. Arystarkhova, K.J. Barr, R.K. Wetzel, J. Peng, K. Markham, K.J. Sweadner, G.H. Fong, and G.M. Kidder. 2005. Na,K-ATpase From Mice Lacking the Gamma Subunit (FXYD2) Exhibits Altered Na+ Affinity and Decreased Thermal Stability. Journal of Biological Chemistry 280 (19): 19003-19011.

Kvietys, P.R.

Leco, K.J.

Fedak, P.W.M., D.S. Smookler, Z. Kassiri, N. Ohno, K.J. Leco, S. Verma, D.A.G. Mickle, K.L. Watson, C.V. Hojilla, W. Cruz, R.D. Weisel, R.K. Li, and R. Khokha. 2004. Timp-3 Deficiency Leads to Dilated Cardiomyopathy. Circulation 110 (16): 2401-2409.

Leung, L.S.

Leung, L.S., K.J. Canning, and B.X. Shen. 2005. Hippocampal Afterdischarges After Gaba(B)-Receptor Blockade in the Freely Moving Rat. Epilepsia 46 (2): 203-216.

Leung, L.S., and B.X. Shen. 2004. Glutamatergic Synaptic Transmission Participates in Generating the Hippocampal Eeg. Hippocampus 14 (4): 510-525.

Liu, X.H., and L.S. Leung. 2004. Sodium-Activated Potassium Conductance Participates in the Depolarizing Afterpotential Following a Single Action Potential in Rat Hippocampal Ca1 Pyramidal Cells. Brain Research 1023 (2): 185-192.

Ma, J.Y., B.X. Shen, N. Rajakumar, and L.S. Leung. 2004. The Medial Septum Mediates Impairment of Prepulse Inhibition of Acoustic Startle Induced by a Hippocampal Seizure or Phencyclidine. Behavioural Brain Research 155 (1): 153-166.

Mirsattari, S.M., F. Bihari, L.S. Leung, R.S. Menon, Z. Wang, J.R. Ives, and R. Bartha. 2005. Physiological Monitoring of Small Animals During Magnetic Resonance Imaging. Journal of Neuroscience Methods 144 (2): 207-213.

Mirsattari, S.M., J.R. Ives, F. Bihari, L.S. Leung, R.S. Menon, and R. Bartha. 2005. Real-Time Display of Artifact-Free Electroencephalography During Functional Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in an Animal Model of Epilepsy. Magnetic Resonance in Medicine 53 (2): 456-464.

Stewart, L.S., and L.S. Leung. 2005. Hippocampal Melatonin Receptors Modulate Seizure Threshold. Epilepsia 46 (4): 473-480.

Martin, J.

Barkun, A., C.A. Fallone, N. Chiba, and et.al. 2004. A Canadian Clinical Practice Algorithm for the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding. Canadian Journal of Gastroenterology 18 (10): 605-609.

Narayanan, N.

Narayanan, N., C.X. Yang, and A. Xu. 2004. Dexamethasone Treatment Improves Sarcoplasmic Reticulum Function and Contractile Performance in Aged Myocardium. Molecular and Cellular Biochemistry 266 (1-2): 31-36.

Rylett, R.J.

Dobransky, T., A. Doherty-Kirby, A.R. Kim, D. Brewer, G. Lajoie, and R.J. Rylett. 2004. Protein Kinase C Isoforms Differentially Phosphorylate Human Choline Acetyltransferase Regulating Its Catalytic Activity. Journal of Biological Chemistry 279 (50): 52059-52068.

Kim, A.R., A. Doherty-Kirby, G. Lajoie, R.J. Rylett, and B.H. Shilton. 2005. Two Methods for Large-Scale Purification of Recombinant Human Choline Acetyltransferase. Protein Expression and Purification 40 (1): 107-117.

Sims, S.M.

Charras, G.T., B.A. Williams, S.M. Sims, and M.A. Horton. 2004. Estimating the Sensitivity of Mechanosensitive Ion Channels to Membrane Strain and Tension. Biophysical Journal 87 (4): 2870-2884.

Williams, B.A., C.Q. Liu, L. Deyoung, G.B. Brock, and S.M. Sims. 2005. Regulation of Intracellular Ca2+ Release in Corpus Cavernosum Smooth Muscle: Synergism Between Nitric Oxide and Cgmp. American Journal of Physiology-Cell Physiology 288 (3): C650-C658.

Vilis, T.

Ferber, S., G.K. Humphrey, and T. Vilis. 2005. Segregation and Persistence of Form in the Lateral Occipital Complex. Neuropsychologia 43 (1): 41-51.

Large, M.E., A. Aldcroft, and T. Vilis. 2005. Perceptual Continuity and the Emergence of Perceptual Persistence in the Ventral Visual Pathway. Journal of Neurophysiology 93 (6): 3453-3462.

Niemeier, M., H.C. Goltz, A. Kuchinad, D.B. Tweed, and T. Vilis. 2005. A Contralateral Preference in the Lateral Occipital Area: Sensory and Attentional Mechanisms. Cerebral Cortex 15 (3): 325-331.

Wagner, G.F.

Gagliardi, A.D., E.Y.W. Kuo, S. Raulic, G.F. Wagner, and G.E. Dimattia. 2005. Human Stanniocalcin-2 Exhibits Potent Growth-Suppressive Properties in Transgenic Mice Independently of Growth Hormone and Igfs. American Journal of Physiology-Endocrinology and Metabolism 288 (1): E92-E105.

James, K., M. Seitelbach, C.R. Mccudden, and G.F. Wagner. 2005. Evidence for Stanniocalcin Binding Activity in Mammalian Blood and Glomerular Filtrate. Kidney International 67 (2): 477-482.

Paciga, M., G.E. Dimattia, and G.F. Wagner. 2004. Regulation of Luteal Cell Big Stanniocalcin Production and Secretion. Endocrinology 145 (9): 4204-4212.

Tanega, C., D.P. Radman, B. Flowers, T. Sterba, and G.F. Wagner. 2004. Evidence for Stanniocalcin and a Related Receptor in Annelids. Peptides 25 (10): 1671-1679.

Wang, R.

Peters, K., R. Panienka, J.M. Li, G. Kloppel, and R.N. Wang. 2005. Expression of Stem Cell Markers and Transcription Factors During the Remodeling of the Rat Pancreas After Duct Ligation. Virchows Archiv 446 (1): 56-63.

Rosenberg, L., M. Lipsett, J.W. Yoon, M. Prentki, R. Wang, H.S. Jun, G. Pittenger, D. Taylor-Fishwick, and A. Vinick. 2004. Apentdecapeptide fragment of Islet Neogenesis Associated Protein (INGAP) increases beta cell mass and reverses diabetes in C57BL/6J mice. Annals of Surgery 240 (5): 875-884.

Wang, R., J. Li, N. Yashpal, and N. Gao. 2005. Nestin Expression and Clonal Analysis of Islet-Derived Epithelial Monolayers: Insight Into Nestin-Expressing Cell Heterogeneity and Differentiation Potential. Journal of Endocrinology 184 (2): 329-339.

Wang, R., N. Yashpal, F. Bacchus, and J. Li. 2004. Hepatocyte Growth Factor Regulates Proliferation and Differentiation of Epithelial Monolayers Derived From Islets of Postnatal Rat Pancreas. Journal of Endocrinology 183 (1): 163-171.

Wang, R.N., J.M. Li, and N. Yashpal. 2004. Phenotypic Analysis of C-Kit Expression in Epithelial Monolayers Derived From Postnatal Rat Pancreatic Islets. Journal of Endocrinology 182 (1): 113-122.

Yashpal, N.K., J.M. Li, M.B. Wheeler, and R.N. Wang. 2005. Expression of Beta 1 Integrin Receptors During Rat Pancreas Development - Sites and Dynamics. Endocrinology 146 (4): 1798-1807.

Weaver, L.C.

Brown, A., M.J. Ricci, and L.C. Weaver. 2004. NGF Message and Protein Distribution in the Injured Rat Spinal Cord. Experimental Neurology 188 (1): 115-127.

Oatway, M.A., Y.H. Chen, J.C. Bruce, G.A. Dekaban, and L.C. Weaver. 2005. Anti-Cd11d Integrin Antibody Treatment Restores Normal Serotonergic Projections to the Dorsal, Intermediate, and Ventral Horns of the Injured Spinal Cord. Journal of Neuroscience 25 (3): 637-647.

Oatway, M.A., Y.H. Chen, and L.C. Weaver. 2004. The 5-Ht3 Receptor Facilitates at-Level Mechanical Allodynia Following Spinal Cord Injury. Pain 110 (1-2): 259-268.

Saville, L.R., C.H. Pospisil, L.A. Mawhinney, F. Bao, F.C. Simedrea, A.A. Peters, P.J. O'connell, L.C. Weaver, and G.A. Dekaban. 2004. A Monoclonal Antibody to Cd11d Reduces the Inflammatory Infiltrate Into the Injured Spinal Cord: a Potential Neuroprotective Treatment. Journal of Neuroimmunology 156 (1-2): 42-57.

Xia, Y.

Cao, Q.Y., Y. Xia, M. Azadniv, and I.N. Crispe. 2004. The E2f-1 Transcription Factor Promotes Caspase-8 and Bid Expression, and Enhances Fas Signaling in T Cells. Journal of Immunology 173 (2): 1111-1117.