Leaders in Learning: Publications of Faculty & Staff


 Biochemistry: 1998-1999

 

AINSWORTH, P.J.

Ainsworth, P.J., C.F. Bolton, B.C. Murphy, J.A. Stuart, and A.F. Hahn. 1998. Genotype/phenotype correlation in affected individuals of a family with a deletion of the entire coding sequence of the connexin 32 gene. American Journal of Human Genetics 103: 242-244.

 

BARBER, K.R.

Jones, D.H., K.R. Barber, E.W. VanDerLoo, and C.W.M. Grant . 1998. Epidermal Growth Factor Receptor Transmembrane Domain: 2H NMR Implications for Orientation and Motion in a Bilayer Environment. Biochemistry 37: 16780-16787.

 

BRANDL, C.J.

Saleh, A., D. Schieltz, N. Ting, S.B. McMahon, D.W. Litchfield, J.R. Yates III, S.P. Lees-Miller, M.D. Cole, and C.J. Brandl. 1998. Tra1p Is a Component of the Yeast Ada Spt Transcriptional Regulatory Complexes. Journal of Biological Chemistry 273 (41): 26559-26565.

 

BRIDGER, W.A.

Bailey, D.L., M.E. Fraser, W.A. Bridger, M.N.G. James, and W.T. Wolodko. 1999. A Dimeric Form of Escherichia coli Succinyl-CoA Synthetase Produced by Site- Directed Mutagenesis. Journal of Molecular Biology 285: 1655-1666.

Fraser, M.E., M.N.G. James, W.A. Bridger, and W.T. Wolodko . 1999. A Detailed Structural Description of Escherichia coli Succinyl-CoA Synthetase. Journal of Molecular Biology 285: 1633-1653.

Joyce, M.A., M.E. Fraser, E.R. Brownie, M.N.G. James, W.A. Bridger, and W.T. Wolodko. 1999. Probing the Nucleotide-Binding Site of Escherichia coli Succinyl-CoA Synthetase. Biochemistry 38 (22): 7273-7283.

 

CHACONAS, G.

Naigamwalla, D.Z., C.J. Coros, Z. Wu, and G. Chaconas. 1998. Mutations in Domain IIIa of the Mu Transposase: Evidence Suggesting an Active Site Component which Interacts with the Mu-Host Junction. Journal of Molecular Biology 282: 265-274.

 

FRASER, M.E.

Bailey, D.L., M.E. Fraser, W.A. Bridger, M.N.G. James, and W.T. Wolodko. 1999. A Dimeric Form of Escherichia coli Succinyl-CoA Synthetase Produced by Site- Directed Mutagenesis. Journal of Molecular Biology 285: 1655-1666.

Fraser, M.E., M.N.G. James, W.A. Bridger, and W.T. Wolodko . 1999. A Detailed Structural Description of Escherichia coli Succinyl-CoA Synthetase. Journal of Molecular Biology 285: 1633-1653.

Joyce, M.A., M.E. Fraser, E.R. Brownie, M.N.G. James, W.A. Bridger, and W.T. Wolodko. 1999. Probing the Nucleotide-Binding Site of Escherichia coli Succinyl-CoA Synthetase. Biochemistry 38 (22): 7273-7283.

 

GLOOR, G.B.

Gloor, G.B., T. Dray, and K. Keeler. Analyzing Double-Strand Repair Events in Drosophila (Chapter 34). Methods in Molecular Biology, Volume 113: DNA Repair Protocols: Eukaryotic Systems. D.S. Henderson. Totawa, NJ: Humana Press Inc. 425-438.

 

GRANT, C.W.M.

Jones, D.H., K.R. Barber, E.W. VanDerLoo, and C.W.M. Grant . 1998. Epidermal Growth Factor Receptor Transmembrane Domain: 2H NMR Implications for Orientation and Motion in a Bilayer Environment. Biochemistry 37: 16780-16787.

 

HAINES, D.S.M.

Tonkin, K.S., J.W. McKay, L.W. Stitt, S. Tokmakejian, and D.S.M. Haines. 1999. Tumour epidermal growth factor receptor, erbB-2 and cathepsin D in node-negative invasive breast cancer: their impact on the selection of patients for systemic adjuvant therapy. Cancer Prevention & Control 3 (2): 131-136.

 

HAN, V.K.M.

Bradshaw, S.L., A.J. D'Ercole, and V.K.M. Han. 1999. Overexpression of Insulin-Like Growth Factor-Binding Protein-2 in C6 Glioma Cells Results in Conditional Alteration of Cellular Growth. Endocrinology 140 (2): 575-584.

Braems, G.A., V.K.M. Han, and J.R.G. Challis. 1998. Gestational age-dependent changes in the levels of mRNAs encoding cortisol biosynthetic enzymes and IGF-II in the adrenal gland of fetal sheep during prolonged hypoxemia. Journal of Endocrinology 159: 257-264.

Carter, A.M., B. Tanswell, K. Thompson, and V.K.M. Han. 1998. Immunohistochemical Identification of Epithelial and Mesenchymal Cell Types in the Chorioallantoic and Yolk Sac Placentae of the Guinea-pig. Placenta 19: 489-500.

Hamilton, G.S., J.J. Lysiak, V.K.M. Han, and P.K. Lala. 1998. Autocrine-Paracrine Regulation of Human Trophoblast Invasiveness by Insulin- like Growth Factor (IGF)-II and IGF-Binding Protein (IGFBP)-1. Experimental Cell Research 244: 147-156.

Han, V.K.M. 1999. Intrauterine Growth Restriction and Mechanisms of Fetal Growth. Encyclopedia of Reproduction, Volume 2. E. Knobil, and J.D. Neill. San Diego, CA: Academic Press. 877-892.

Han, V.K.M., A.M. Carter, S. Chandarana, B. Tanswell, and K. Thompson. 1999. Ontogeny of Expression of Insulin-like Growth Factor (IGF) and IGF Binding Protein mRNAs in the Guinea-pig Placenta and Uterus. Placenta 20: 361-377.

Han, V.K.M., and J.R.G. Challis. 1998. Maternal Nutrition and Fetal Growth: The Role of Insulin-like Growth Factors (IGFs) and IGF Binding Proteins (IGFBPs). Nutrition and Reproduction. Pennington Center Nutrition Series, Volume 8. W. Hansel, G.A. Bray, and D.H. Ryan. Baton Rouge: Louisiana State University Press. 215-228.

Hill, D.J., J. Hogg, J. Petrik, E. Arany, and V.K.M. Han. 1999. Cellular distribution and ontogeny of insulin-like growth factors (IGFs) and IGF binding protein messenger RNAs and peptides in developing rat pancreas. Journal of Endocrinology 160: 305-317.

 

HANIFORD, D.B.

Allingham, J.S., P.A. Pribil, and D.B. Haniford. 1999. All Three Residues of the Tn10 Transposase DDE Catalytic Triad Function in Divalent Metal Ion Binding. Journal of Molecular Biology 289: 1195-1206.

Kennedy, A.K., A. Guhathakurta, N. Kleckner, and D.B. Haniford. 1998. Tn10 Transposition via a DNA Hairpin Intermediate. Cell 95 (October): 125-134.

 

HEGELE, R.A.

Anand, S.S., S. Yusuf, V. Vuksan, S. Devansen, P. Montague, L. Kelemen, J. Bosch, C.S. Bmath, K.K. Teo, E. Lonn, H.C. Gerstein, R.A. Hegele, and M. McQueen. 1998. The Study of Health Assessment and Risk in Ethnic group (SHARE): Rationale and design. Canadian Journal of Cardiology 14 (11): 1349-1357.

Boright, A.P., P.W. Connelly, J.H. Brunt, S.W. Scherer, L.C. Tsui, and R.A. Hegele. 1998. Genetic variations in paraoxonase-1 and paraoxonase-2 is associated with variation in plasma lipoproteins in Alberta Hutterites. Atherosclerosis 139: 131-136.

Busch, C.P., D.D. Ramdath, S. Ramsewak, and R.A. Hegele. 1999. Association of PON2 variation with birth weight in Trinidadian neonates of South Asian ancestry. Pharmacogenetics 9: 351-356.

Connelly, P.W., and R.A. Hegele. 1998. Hepatic Lipase Deficiency. Critical Reviews in Clinical Laboratory Sciences 35 (6): 547-572.

Connelly, P.W., M. Poapst, J. Davignon, S. Lussier-Cacan, B. Reeder, R. Lessard, R.A. Hegele, and A. Csima. 1999. Reference values of plasma apolipoproteins A-I and B, and association with nonlipid risk factors in the populations of two Canadian provinces: Quebec and Saskatchewan. Canadian Journal of Cardiology 15 (4): 409-418.

Hegele, R.A. 1999. Genetic prediction of coronary heart disease: lessons from Canada. Scandinavian Journal of Clinical and Laboratory Investigation 59 (Suppl. 230): 153-167.

Hegele, R.A. 1999. Genetics in childhood atherosclerosis. Progress in Pediatric Cardiology 9: 213-224.

Hegele, R.A. 1999. Lessons from Genetic Studies in Native Canadian Populations. Nutrition Reviews 57 (5): S43-S50.

Hegele, R.A. 1999. Paraoxonase genes and disease. Trends in Molecular Medicine 31: 217-224.

Hegele, R.A. 1998. A Review of Intestinal Fatty Acid Binding Protein Gene Variation and the Plasma Lipoprotein Response to Dietary Components. Clinical Biochemistry 31 (8): 609-612.

Hegele, R.A., W.C. Breckenridge, D.W. Cox, G.F. Maguire, J.A. Little, and P.W. Connelly. 1998. Elevated LDT Triglyceride Concentrations in Subjects Heterozygous for the Hepatic Lipase S267F Variant. Arteriosclerosis, Thrombosis, and Vascular Biology 18: 1212-1216.

Hegele, R.A., H. Cao, S.B. Harris, A.J.G. Hanley, and B. Zinman. 1999. The Hepatic Nuclear Factor-1a G319S Variant Is Associated with Early-Onset Type 2 Diabetes in Canadian Oji-Cree. The Journal of Clinical Endocrinology & Metabolsim 84 (3): 1077-1082.

Hegele, R.A., S.B. Harris, P.W. Connelly, A.J.G. Hanley, L.C. Tsui, B. Zinman, and S.W. Scherer. 1998. Genetic variation in paraoxonase-2 is associated with variation in plasma lipoproteins in Canadian Oji-Cree. Clinical Genetics 54: 394-399.

Hegele, R.A., S.B. Harris, A.J.G. Hanley, H. Cao, and B. Zinman. 1998. G Protein ß3 Subunit Gene Variant and Blood Pressure Variation in Canadian Oji-Cree. Hypertension 32: 688-692.

Hegele, R.A., S.B. Harris, A.J.G. Hanley, and B. Zinman. 1999. Association between AGT codon 235 polymorphism and variation in serum concentrations of creatinine and urea in Canadian Oji-Cree. Clinical Genetics 55: 438-443.

Hegele, R.A., S.B. Harris, A.J.G. Hanley, and B. Zinman. 1999. Association Between AGT T235 Variant and Microalbuminuria in Canadian Oji-Cree with Type 2 Diabetes Mellitus. Clinical Biochemistry 32 (3): 201-205.

Hegele, R.A., S.B. Harris, B. Zinman, and A.J.G. Hanley. 1999. Increased Plasma Apolipoprotein B-Containing Lipoproteins Associated with Increased Urinary Albumin Within the Microalbuminuria Range in Type 2 Diabetes. Clinical Biochemistry 32 (2): 143-148.

Hegele, R.A., S.B. Harris, B. Zinman, J. Wang, H. Cao, A.J.G. Hanley, L.C. Tsui, and S.W. Scherer. 1998. Variation in the AU(AT)-Rich Element within the 3'-Untranslated Region of PPP1R3 Is Associated with Variation in Plasma Glucose in Aboriginal Canadians. Journal of Clinical Endocrinology and Metabolism 83 (11): 3980-3983.

Hegele, R.A., J.A. Little, and P.W. Connelly. 1999. Atorvastatin in the management of an index patient with complete hepatic lipase deficiency. Atherosclerosis 143: 219-222.

Hegele, R.A., F. Sun, S.B. Harris, C. Anderson, A.J.G. Hanley, and B. Zinman. 1999. Genome-wide scanning for type 2 diabetes susceptibility in Canadian Oji-Cree, using 190 microsatellite markers. Journal of Human Genetics 44: 10-14.

Spence, J.D., P.A. Barnett, D.E. Bulman, and R.A. Hegele. 1999. An approach to ascertain probands with a non-traditional risk factor for carotid atherosclerosis. Atherosclerosis 144: 429-434.

Spence, J.D., M.R. Malinow, P.A. Barnett, A.J. Marian, D. Freeman, and R.A. Hegele. 1999. Plasma Homocyst(e)ine Concentration, But Not MTHFR Genotype, Is Associated With Variation in Carotid Plaque Area. Stroke 30: 969-973.

Wang, J., D.W. Killinger, and R.A. Hegele. 1999. A Microdeletion within DAX-1 in X-Linked Adrenal Hypoplasia Congenita and Hypogonadotrophic Hypogonadism. The Journal of Investigative Medicine 47 (5): 232-235.

Whitman, S.C., C.A. Argmann, C.G. Sawyez, D.B. Miller, and R.A. Hegele. 1999. Uptake of type IV hypertriglyceridemic VLDL by cultured macrophages is enhanced by interferon-g. Journal of Lipid Research 40: 1017-1028.

Whitman, S.C., S.L. Hazen, D.B. Miller, R.A. Hegele, J.W. Heinecke, and M.W. Huff. 1999. Modification of Type III VLDL, Their Remnants, and VLDL From ApoE-Knockout Mice by p-Hydroxyphenylacetaldehyde, a Product of Myeloperoxidase Activity, Causes Marked Cholesteryl Ester Accumulation in Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology 19: 1238-1249.

 

HENDERSON, A.R.

Apple, F.S., and A.R. Henderson. 1999. Cardiac Function (Chapter 34). Tietz Textbook of Clinical Chemistry. 3rd ed. C.A. Burtis, and E.R. Ashwood. Philadelphia, PA: W.B. Saunders Company. 1178-1203.

Henderson, A.R., and A.D. Rinker. 1999. Gastric, Pancreatic, and Intestinal Function (Chapter 36). Tietz Textbook of Clinical Chemistry. 3rd ed. C.A. Burtis, and E.R. Ashwood. Philadelphia, PA: W.B. Saunders Company. 1271-1327.

Krishnan, S., S. Webb, A.R. Henderson, C.M. Cheung, D.J. Nazir, and H. Richardson. 1999. An overview of Quality Control Practices in Ontario with Particular Reference to Cholesterol Analysis. Clinical Biochemistry 32 (2): 93-99.

Moss, D.W., and A.R. Henderson. 1999. Clinical Enzymology (Chapter 22). Tietz Textbook of Clinical Chemistry. 3rd ed. C.A. Burtis, and E.R. Ashwood. Philadelphia, PA: W.B. Saunders Company. 617-721.

 

HOBKIRK, R.

Goldhawk, D.E., and R. Hobkirk. 1998. Transfer of [3H]estrone-[35S]sulfate Across Guinea Pig Fetal Membranes. Journal of Steroid Biochemistry and Molecular Biology 67 (1): 33-40.

 

HUFF, M.W.

Burnett, J.R., H.R. Barrett, P. Vicini, D.B. Miller, D.E. Telford, S.J. Kleinstiver, and M.W. Huff. 1998. The HMG-CoA Reductase Inhibitor Atorvastatin Increases the Fractional Clearance Rate of Postprandial Triglyceride-Rich Lipoproteins in Miniature Pigs. Arteriosclerosis, Thrombosis, and Vascular Biology 18: 1906-1914.

Burnett, J.R., L.J. Wilcox, D.E. Telford, S.J. Kleinstiver, P.H.R. Barrett, and M.W. Huff. 1998. Inhibition of cholesterol esterification by DuP 128 decreases hepatic apolipoprotein B secretion in vivo: effect of dietary fat and cholesterol. Biochimica et Biophysica Acta 1393: 63-79.

Whitman, S.C., S.L. Hazen, D.B. Miller, R.A. Hegele, J.W. Heinecke, and M.W. Huff. 1999. Modification of Type III VLDL, Their Remnants, and VLDL From ApoE-Knockout Mice by p-Hydroxyphenylacetaldehyde, a Product of Myeloperoxidase Activity, Causes Marked Cholesteryl Ester Accumulation in Macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology 19: 1238-1249.

Wilcox, L.J., P.H.R. Barrett, and M.W. Huff. 1999. Differential regulation of apolipoprotein B secretion from HepG2 cells by two HMG-CoA reductase inhibitors, atorvastatin and simvastatin. Journal of Lipid Research 40: 1078-1089.

Wilcox, L.J., P.H.R. Barrett, R.S. Newton, and M.W. Huff. 1999. ApoB100 Secretion From HepG2 Cells is Decreased by the ACAT Inhibitor CI-1011: An Effect Associated with Enhanced Intracellular Degradation of ApoB. Arteriosclerosis, Thrombosis, and Vascular Biology 19: 939-949.

 

JUNG, J.H.

Schnur, R.E., M. Gao, P.A. Wick, M. Keller, P.J. Benke, M.J. Edwards, A.W. Grix, A. Hockey, J.H. Jung, K.K. Kidd, M. Kistenmacher, A.V. Levin, R.A. Lewis, M.A. Musarella, R.W. Nowakowski, S.J. Orlow, R.S. Pagon, D.A.M. Pillers, H.H. Punnett, G.E. Quinn, K. Tezcan, J. Wagstaff, and R.G. Weleber. 1998. OA1 Mutations and Deletions in X-Linked Ocular Albinism. American Journal of Human Genetics 62: 800-809.

 

KONERMANN, L.

Konermann, L., and D.J. Douglas. 1998. Unfolding of Proteins Monitored by Electrospray Ionization Mass Spectrometry: A Comparison of Positive and Negative Ion Modes. Journal of the American Society for Mass Spectrometry 9: 1248-1254.

 

LEUNG, F.Y.

Grace, D.M., M.A.H. Alfieri, and F.Y. Leung. 1998. Alcohol and Poor Compliance as Factors in Wernicke's Encephalopathy Diagnosed 13 Years After Gastric Bypass. Canadian Journal of Surgery 41 (5): 389-392.

 

LITCHFIELD, D.W.

Bosc, D.G., B. Lüscher, and D.W. Litchfield. 1999. Expression and regulation of protein kinase CK2 during the cell cycle. Molecular and Cellular Biochemistry 191: 213-222.

Chan, A.K., S. Persad, D.W. Litchfield, and J.A. Wright. 1999. Ribonucleotide reductase R2 protein is phosphorylated at serine-20 by P34cdc2 kinase. Biochimica et Biophysica Acta 1448: 363-371.

Raman, C., A. Kuo, J. Deshane, D.W. Litchfield, and R.P. Kimberly. 1998. Regulation of Casein Kinase 2 by Direct Interaction with Cell Surface Receptor CD5. Journal of Biological Chemistry 273 (30): 19183-19189.

Saleh, A., D. Schieltz, N. Ting, S.B. McMahon, D.W. Litchfield, J.R. Yates III, S.P. Lees-Miller, M.D. Cole, and C.J. Brandl. 1998. Tra1p Is a Component of the Yeast Ada Spt Transcriptional Regulatory Complexes. Journal of Biological Chemistry 273 (41): 26559-26565.

Vilk, G., R.B. Saulnier, R. St. Pierre, and D.W. Litchfield. 1999. Inducible Expression of Protein Kinase CK2 in Mammalian Cells. Journal of Biological Chemistry 274 (20): 14406-14414.

 

LO, T.C.Y.

Mazzuca, D.M., and T.C.Y. Lo. 1998. Alteration of myogenic regulatory components in a rat myoblast GLUT 3- mutant. Biochimica et Biophysica Acta 1414: 16-30.

 

MEAKIN, S.O.

Meakin, S.O., and J.I.S. MacDonald. 1998. A Novel Juxtamembrane Deletion in Rat TrkA Blocks Differentiative but Not Mitogenic Cell Signaling in Response to Nerve Growth Factor. Journal of Neurochemistry 71: 1875-1888.

Meakin, S.O., J.I.S. MacDonald, E.A. Gryz, C.J. Kubu, and J.M. Verdi. 1999. The Signaling Adapter FRS-2 Competes with Shc for Binding to the Nerve Growth Factor Receptor TrkA. The Journal of Biological Chemistry 274 (14): 9861-9870.

 

SHILTON, B.

Shilton, B., D.I. Svergun, V.V. Volkov, M.H.J. Koch, S. Cusack, and A. Economou. 1998. Escherichia coli SecA shape and dimensions. FEBS Letters 436: 277-282.

 

SKERJANC, I.S.

Skerjanc, I.S., H. Petropoulos, A.G. Ridgeway, and S. Wilton. 1998. Myocyte Enhancer Factor 2C and Nkx2-5 Up-regulate Each Other's Expression and Initiate Cardiomyogenesis in P19 Cells. The Journal of Biological Chemistry 273 (52): 34904-34910.

 

ST. PIERRE, R.

Vilk, G., R.B. Saulnier, R. St. Pierre, and D.W. Litchfield. 1999. Inducible Expression of Protein Kinase CK2 in Mammalian Cells. Journal of Biological Chemistry 274 (20): 14406-14414.

 

TOKMAKEJIAN, S.

Tonkin, K.S., J.W. McKay, L.W. Stitt, S. Tokmakejian, and D.S.M. Haines. 1999. Tumour epidermal growth factor receptor, erbB-2 and cathepsin D in node-negative invasive breast cancer: their impact on the selection of patients for systemic adjuvant therapy. Cancer Prevention & Control 3 (2): 131-136.

 

TREVITHICK, J.R.

Bantseev, V., K. Herbert, J.G. Sivak, and J.R. Trevithick. 1999. Laser Scanning Focal Length Variability is a Measure of Damage in Rat Lens in Model Astronaut Cataracts Treated With Vitamin E (VE) or R-a-Lipoic Acid (RLA). Ocular Radiation Risk Assessment in Populations Exposed to Environmental Radiation Contamination. A.K. Junk, Y. Kundiev, P. Vitte, and B.V. Worgul. Netherlands: Kluwer Academic Publishers; NATO Scientific Affairs Division. 173-182.

Kilic, F., G.J. Handelman, K. Traber, K. Tsang, L. Packer, and J.R. Trevithick. 1998. Modelling Cortical Cataractogenesis XX. In Vitro Effect of a-Lipoic Acid on Glutathione Concentrations in Lens in Model Diabetic Cataractogenesis. Biochemistry and Molecular Biology International 46 (3): 585-595.

Trevithick, J.R., and K.P. Mitton. 1999. Uptake of Vitamin E Succinate by the Skin, Conversion to Free Vitamin E, and Transport to Internal Organs. Biochemistry and Molecular Biology International 47 (3): 509-518.

 

WILTON, S.

Skerjanc, I.S., H. Petropoulos, A.G. Ridgeway, and S. Wilton. 1998. Myocyte Enhancer Factor 2C and Nkx2-5 Up-regulate Each Other's Expression and Initiate Cardiomyogenesis in P19 Cells. The Journal of Biological Chemistry 273 (52): 34904-34910.