The University of Western Ontario

Rau, S.E., J.R. Bend, J.M.O. Arnold, L.T. Tran, J.D. Spence, and D.G. Bailey. 1997. Grapefruit Juice-Terfenadine Single-Dose Interaction: Magnitude, Mechanism, and Relevance. Clinical Pharmacology and Therapeutics 61 (4): 401-409.

Rau, S.E., J.R. Bend, J.M.O. Arnold, L.T. Tran, J.D. Spence, and D.G. Bailey. 1997. Grapefruit Juice-Terfenadine Single-Dose Interaction: Magnitude, Mechanism, and Relevance. Clinical Pharmacology and Therapeutics 61 (4): 401-409.

Karmazyn, M., and J.R. Bend. 1997. Biochemical and Molecular Mechanisms of Myocardial Injury (Chapter 6.16). Comprehensive Toxicology. Cardiovascular Toxicology, Volume 6. G. Sipes, C.A. McQueen, and A.J. Gandolfi. New York, NY: Elsevier Science. 255-278.

Kent, U.M., J.R. Bend, B.A. Chamberlin, D.A. Gage, and P.F. Hollenberg. 1997. Mechanism-Based Inactivation of Cytochrome P450 2B1 by N-Benzyl-1-aminobenzotriazole. Chemical Research in Toxicology 10 (5): 600-608.

McCallum, G.P., A.C. Weedon, P. Krug, and J.R. Bend. 1996. Microsomal Cytochrome P450 Peroxygenase Metabolism of Arachidonic Acid in Guinea Pig Liver. Journal of Pharmacology and Experimental Therapeutics 278 (3): 1188-1194.

Rau, S.E., J.R. Bend, J.M.O. Arnold, L.T. Tran, J.D. Spence, and D.G. Bailey. 1997. Grapefruit Juice-Terfenadine Single-Dose Interaction: Magnitude, Mechanism, and Relevance. Clinical Pharmacology and Therapeutics 61 (4): 401-409.

Sinal, C.J., and J.R. Bend. 1996. Kinetics and Selectivity of Mechanism-Based Inhibition of Guinea Pig Hepatic and Pulmonary Cytochrome P450 by N-Benzyl-1-Aminobenzotriazole and N-a-Methylbenzyl-1-Aminobenzotriazole. Drug Metabolism and Disposition 24 (9): 996-1001.

Woodcroft, K.J., C.D. Webb, M. Yao, A.C. Weedon, and J.R. Bend. 1997. Metabolism of the Cytochrome P450 Mechanism-Based Inhibitor N-Benzyl-1-aminobenzotriazole to Products that Covalently Bind with Protein in Guinea Pig Liver and Lung Microsomes: Comparative Study with 1-Aminobenzotriazole. Chemical Research in Toxicology 10 (5): 589-599.

Moneta, N., T.J. McDonald, and M.A. Cook. 1997. Endogenous Adenosine Inhibits Evoked Substance P Release From Perifused Networks of Myenteric Ganglia. American Journal of Physiology 272 (35): G38-G45.

Ebihara, Y., and M. Karmazyn. 1996. Inhibition of b- but not a₁-Mediated Adrenergic Responses in Isolated Hearts and Cardiomyocytes by Nitric Oxide and 8-Bromo Cyclic GMP. Cardiovascular Research 32: 622-629.

Hoque, A.N.E., J.V. Haist, and M. Karmazyn. 1997. Na⁺ -H⁺ Exchange Inhibition Protects Against Mechanical, Ultrastructural, and Biochemical Impairment Induced by Low Concentrations of Lysophosphatidylcholine in Isolated Rat Hearts. Circulation Research 80 (1): 95-102.

Hammond, J.R. 1997. Enhancement of the Functional Stability of Solubilized Nucleoside Transporters by Substrates and Inhibitors. Biochemical Pharmacology 53: 623-629.

Hammond, J.R., and M. Zarenda. 1996. Effect of Detergents on Ligand Binding and Translocation Activities of Solubilized/Reconstituted Nucleoside Transporters. Archives of Biochemistry and Biophysics 332 (2): 313-322.

Hoque, A.N.E., J.V. Haist, and M. Karmazyn. 1997. Na⁺ -H⁺ Exchange Inhibition Protects Against Mechanical, Ultrastructural, and Biochemical Impairment Induced by Low Concentrations of Lysophosphatidylcholine in Isolated Rat Hearts. Circulation Research 80 (1): 95-102.

Hoque, A.N.E., and M. Karmazyn. 1997. Effect of Sodium-Hydrogen Exchange Inhibition on Functional and Metabolic Impairment Produced by Oxidative Stress in the Isolated Rat Heart. Canadian Journal of Physiology and Pharmacology 75: 326-334.

Ebihara, Y., and M. Karmazyn. 1996. Inhibition of b- but not a₁-Mediated Adrenergic Responses in Isolated Hearts and Cardiomyocytes by Nitric Oxide and 8-Bromo Cyclic GMP. Cardiovascular Research 32: 622-629.

Hoque, A.N.E., J.V. Haist, and M. Karmazyn. 1997. Na⁺ -H⁺ Exchange Inhibition Protects Against Mechanical, Ultrastructural, and Biochemical Impairment Induced by Low Concentrations of Lysophosphatidylcholine in Isolated Rat Hearts. Circulation Research 80 (1): 95-102.

Hoque, A.N.E., and M. Karmazyn. 1997. Effect of Sodium-Hydrogen Exchange Inhibition on Functional and Metabolic Impairment Produced by Oxidative Stress in the Isolated Rat Heart. Canadian Journal of Physiology and Pharmacology 75: 326-334.

Karmazyn, M. 1996. Editorial: Sodium-Hydrogen Exchange Inhibition - A Superior Cardioprotective Strategy. The Journal of Thoracic and Cardiovascular Surgery 112 (3): 776-777.

Karmazyn, M. 1996. Myocardial Ischemia: Mechanisms, Reperfusion, Protection. EXS, 76. Basel, Switzerland: Bikhauser Verlag. xii, 515 pp. Includes bibliographical references and index.

Karmazyn, M. 1996. The Role of Endothelins in Cardiac Function in Health and Disease. Myocardial Ischemia: Mechanisms, Reperfusion, Protection. M. Karmazyn. Basel, Switzerland: Bikhauser Verlag. 209-230.

Karmazyn, M. 1996. The Sodium-Hydrogen Exchange System in the Heart: Its Role in Ischemic and Reperfusion Injury and Therapeutic Implications. Canadian Journal of Cardiology 12 (10): 1074-1082.

Karmazyn, M., and J.R. Bend. 1997. Biochemical and Molecular Mechanisms of Myocardial Injury (Chapter 6.16). Comprehensive Toxicology. Cardiovascular Toxicology, Volume 6. G. Sipes, C.A. McQueen, and A.J. Gandolfi. New York, NY: Elsevier Science. 255-278.

Moneta, N., T.J. McDonald, and M.A. Cook. 1997. Endogenous Adenosine Inhibits Evoked Substance P Release From Perifused Networks of Myenteric Ganglia. American Journal of Physiology 272 (35): G38-G45.

Resendes, M.C., G.C. Kalogeros, S.J. Dixon, and R.B. Philp . 1997. Nitrous Oxide Enhances Na⁺/Ca⁺⁺ Exchange in the Neuroblastoma Cell Line SK-N-SH. The Journal of Pharmacology and Experimental Therapeutics 280 (2): 795-801.

Rau, S.E., J.R. Bend, J.M.O. Arnold, L.T. Tran, J.D. Spence, and D.G. Bailey. 1997. Grapefruit Juice-Terfenadine Single-Dose Interaction: Magnitude, Mechanism, and Relevance. Clinical Pharmacology and Therapeutics 61 (4): 401-409.

Woodcroft, K.J., C.D. Webb, M. Yao, A.C. Weedon, and J.R. Bend. 1997. Metabolism of the Cytochrome P450 Mechanism-Based Inhibitor N-Benzyl-1-aminobenzotriazole to Products that Covalently Bind with Protein in Guinea Pig Liver and Lung Microsomes: Comparative Study with 1-Aminobenzotriazole. Chemical Research in Toxicology 10 (5): 589-599.

Gillesby, B.E., M. Stanostefano, W. Porter, S. Safe, Z.F. Wu, and T.R. Zacharewski. 1997. Identification of a Motif Within the 5' Regulatory Region of pS2 Which is Responsible for AP-1 Binding and TCDD-Mediated Suppression. Biochemistry 36 (20): 6080-6089.

Woodcroft, K.J., C.D. Webb, M. Yao, A.C. Weedon, and J.R. Bend. 1997. Metabolism of the Cytochrome P450 Mechanism-Based Inhibitor N-Benzyl-1-aminobenzotriazole to Products that Covalently Bind with Protein in Guinea Pig Liver and Lung Microsomes: Comparative Study with 1-Aminobenzotriazole. Chemical Research in Toxicology 10 (5): 589-599.

Balaguer, P., A. Joyeux, M.S. Denison, R. Vincent, B.E. Gillesby, and T.R. Zacharewski. 1996. Assessing the Estrogenic and Dioxin-like Activities of Chemicals and Complex Mixtures Using In Vitro Recombinant Receptor-Reporter Gene Assays. Canadian Journal of Physiology and Pharmacology 74: 216-222.

Connor, K., K. Ramamoorthy, M. Moore, M. Mustain, I. Chen, S. Safe, T.R. Zacharewski, B.E. Gillesby, A. Joyeux, and P. Balaguer. 1997. Hydroxylated Polychlorinated Biphenyls (PCBs) as Estrogens and Antiestrogens: Structure-Activity Relationships. Toxicology and Applied Pharmacology 145: 111-123.

Gillesby, B.E., M. Stanostefano, W. Porter, S. Safe, Z.F. Wu, and T.R. Zacharewski. 1997. Identification of a Motif Within the 5' Regulatory Region of pS2 Which is Responsible for AP-1 Binding and TCDD-Mediated Suppression. Biochemistry 36 (20): 6080-6089.

Zacharewski, T.R. 1997. In Vitro Bioassays for Assessing Estrogenic Substances. Environmental Science and Technology 31 (3): 613-623.