The University of Western Ontario

Archer, T.K., E. Zaniewski, M. Moyer, and S.K. Nordeen. 1994. The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells. Molecular Endocrinology 8: 1154-1 162.

Hager, G.L., T.K. Archer, G. Fragoso, E.H. Bresnick, Y. Tsukagoshi, S. John, and C.L. Smith. 1994. The influence of chromatin structure on the binding of transcription factors to DNA. DNA and Chromosomes 58: 63-71.

Mymryk, J.S., and T.K. Archer. 1994. Detection of transcription factor binding in vivo using lambda exonuclease. Nucleic Acids Research 22: 4344-4345.

Mymryk, J.S., D. Berard, G.L. Hager, and T.K. Archer. 1995. MMTV chromatin in human breast cancer cells is constitutively hypersensitive and exhibits steroid hormone independent loading of transcription factors in vivo. Molecular and C ellular Biology 15: 26-34.

Battista, J.J., R.B. Barnett, D.L.D. Mason, C.A. Plume, M.S. MacPherson, B. Fisher, and A.T. Porter. March 1995. New radioactive isotope developed in Canada for cancer brachytherapy. Current Oncology 2 (1): 6-13.

Roth, S.F., R.N. Bohay, and R.B. Barnett. 1995. Surface and internal absorbed doses in mandibular and maxillary occlusal radiography. Journal of the Canadian Dental Association 61 (11): 955-959.

Battista, J.J., R.B. Barnett, D.L.D. Mason, C.A. Plume, M.S. MacPherson, B. Fisher, and A.T. Porter. March 1995. New radioactive isotope developed in Canada for cancer brachytherapy. Current Oncology 2 (1): 6-13.

Breen, S.L., and J.J. Battista. 1995. Radiation dosimetry in human bone using electron paramagnetic resonance. Physical Medicine in Biology 40: 2065-2077.

Jaffray, D., J.J. Battista, A. Fenster, and P. Munro. 1995. Monte Carlo Studies of x-ray energy absorption and quantum noise in megavoltage transmission radiography. Medical Physics 22 (7): 107-108.

MacPherson, M.S., and J.J. Battista. January 1995. Dose distributions and dose rate constants for new Ytterbium-169 brachytherapy seeds. Medical Physics 22 (1): 89-96.

Papiez, L.S., and J.J. Battista. 1994. Radiance and particle fluence. Medical Biology 39: 1053-1062.

Papiez, L.S., J. McLellan, G.A. Sandison, S. Sawchuk, X. Lu, and J.J. Battista. October 1994. Inclusion of energy straggling in a numerical method for electron dose calculation. Medical Physics 21 (10): 1591-1598.

Knowling, M., V. Bramwell, E. Eisenhauer, G. Boos, A. Bodurtha, and I. Quirt. 1994. Phase II trial of 10-EDAM in advanced soft tissue sarcoma : A study of the Canadian Sarcoma Group and the National Cancer Institute of Canada Clinical Trials Group. Annals of Oncology 5: 766-768.

O'Malley, F., Z. Saad, N. Kerkvlient, A.F. Chambers, K. Tonkin, U. Turnbull, and V. Bramwell. 1994. The predictive power of a combination of Ki 67, c-erb B2 and p53 in lymph node negative breast cancer. Modern Pathology 7: 94.

Cairncross, J.G., D.R. Macdonald, S. Ludwin, D. Lee, T. Cascino, J. Buckner, D. Fulton, E. Dropcho, D. Stewart, C. Schold, N. Wainman, and E. Eisenhauer. 1994. Chemotherapy for anaplastic oligodendroglioma. Journal of Clinical Oncology 12: 2 013-2021.

Nutt, C.L., J.F. Costello, L.L. Bambrick, D.B. Yarosh, L.E. Swinnen, A.F. Chambers, and J.G. Cairncross. 1995. 0⁶-Methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage. Canadian Journal of Neurologi cal Sciences 22: 111-115.

Rogers, L.R., M.A. Weinstein, M.l. Estes, J.G. Cairncross, and T. Strachan. 1994. Diffuse bilateral cerebral astrocytomas with a typical neuroimaging studies. Journal of Neurosurgery 81: 817-821.

Watling, C.J., D.H. Lee, D.R. Macdonald, and J.G. Cairncross. 1994. Corticosteroid-induced magnetic resonance imaging changes in patients with recurrent malignant glioma. Journal of Clinical Oncology 12: 1886-1889.

Watling, C.J., D.J. Van Meyel, D.A. Ramsay, D.R. Macdonald, and J.G. Cairncross. 1995. Loss of heterozygosity analysis of chromosomes 9, 10 and 17 in gliomas in familes. Canadian Journal of Neurological Sciences 22: 17-21.

Bautista, D.S., J.W. Xuan, C. Hota, A.F. Chambers, and J.F. Harris. 1994. Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. Journal of Biological Chemistry 269: 23280-23285.

Carroll, K.K., R. Kothapaili, E.M.K. Lui, N. Guthrie, and A.F. Chambers. 1995. Biological effects of long-chain fatty amines. Malaysian Oil Science and Technology 4: 124-125.

Chambers, A.F. 1995. Regulation and function of osteopontin in ras-transformed cells. Annals of the New York Academy of Sciences 760: 101-108.

Denhardt, D.T., and A.F. Chambers. 1994. Overcoming obstacles to metastasis-defenses against host defenses: osteopontin (OPN) as a shield against attack by cytotoxic host cells. Journal of Cellular Biochemistry 56: 48-51.

Guo, X., Y.P. Zhang, D.A. Mitchell, D.T. Denhardt, and A.F. Chambers. 1995. Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlat es with the metastatic potential of the cell. Molecular and Cellular Biology 15: 476-487.

Koop, S., R. Khokha, E.E. Schmidt, I.C. MacDonald, V.L. Morris, A.F. Chambers, and A.C. Groom. 1994. Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Research 54: 4791-4797.

Koop, S., I.C. MacDonald, K. Luzzi, E.E. Schmidt, V.L. Morris, M. Grattan, R. Khokha, A.F. Chambers, and A.C. Groom. 1995. Fate of melanoma cells entering the microcirculation: Over 80% survive and extravasate. Cancer Research 55: 2520-25 23.

Morris, V.L., S. Koop, I.C. MacDonald, E.E. Schmidt, M. Grattan, D. Percy, A.F. Chambers, and A.C. Groom. 1994. Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth. Clinical and Experimental Metastasis 12: 357-367.

Morris, V.L., E.E. Schmidt, S. Koop, I.C. MacDonald, M. Grattan, R. Khokha, M.A. McLande, S. Niewiarowski, A.F. Chambers, and A.C. Groom. 1995. Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis. Experiment al Cell Research 219: 571-578.

Nutt, C.L., J.F. Costello, L.L. Bambrick, D.B. Yarosh, L.E. Swinnen, A.F. Chambers, and J.G. Cairncross. 1995. 0⁶-Methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage. Canadian Journal of Neurologi cal Sciences 22: 111-115.

O'Malley, F., Z. Saad, N. Kerkvlient, A.F. Chambers, K. Tonkin, U. Turnbull, and V. Bramwell. 1994. The predictive power of a combination of Ki 67, c-erb B2 and p53 in lymph node negative breast cancer. Modern Pathology 7: 94.

Xuan, J.W., C. Hota, Y. Shigeyama, J.A. D'Errico, M.J. Somerman, and A.F. Chambers. 1995. Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions. Journal of Cellu lar Biochemistry 57: 680-690.

Smith, A., I. Chin-Yee, and K. Howson-Jan. 1994. Peripheral blood stem cell transplantation versus bone marrow transplantation: re-evaluating eligibility criteria. Current Oncology 1 (3): 181-184.

Perera, F., F. Chisela, J. Engel, and V. Venkatesan. 1995. Method of localization and implantation of the lumpectomy site for high dose rate brachytherapy after conservative surgery for T1 and T2 breast cancer. International Journal of Radiation Oncology, Biology, Physics 31 (4): 959-965.

Gellersen, B., R. Kempf, R. Telgmann, and G.E. DiMattia. 1995. Pituitary-type transcription of the human prolactin gene in the absence of Pit-1. Molecular Endocrinology 9: 887-909.

Lazier, C.B., M. Wiktorowicz, G.E. DiMattia, D.A. Gordon, R. Binder, and D.L. Williams. 1994. Apolipoprotein (APO)B and APO11 gene expression are both estrogen-responsive in chick embryo liver but only APO11 is estrogen-responsive in kidney. Molecular and Cellular Endocrinology 106: 187-194.

Rhodes, S.J., G.E. DiMattia, and M.G. Rosenfeld. 1994. Transcriptional mechanisms in anterior pituitary cell differentiation. Current Opinion in Genetics and Development 4: 709-717.

Rosenfeld, M.G., S. Rhodes, G.E. DiMattia, S.C. Lin, and C.R. Lin. 1994. Transcriptional regulation of mammalian genesis tissue specific factors in specification of cellular phenotypes. Frontiers in Endocrinology: Developmental Endocrinology. 6th ed. P.C. Sizonenko, and M.L. Aubert. Rome, Italy: Ares-Serono Symposia Publication. 1-13.

Perera, F., F. Chisela, J. Engel, and V. Venkatesan. 1995. Method of localization and implantation of the lumpectomy site for high dose rate brachytherapy after conservative surgery for T1 and T2 breast cancer. International Journal of Radiation Oncology, Biology, Physics 31 (4): 959-965.

Jaffray, D., J.J. Battista, A. Fenster, and P. Munro. 1995. Monte Carlo Studies of x-ray energy absorption and quantum noise in megavoltage transmission radiography. Medical Physics 22 (7): 107-108.

Battista, J.J., R.B. Barnett, D.L.D. Mason, C.A. Plume, M.S. MacPherson, B. Fisher, and A.T. Porter. March 1995. New radioactive isotope developed in Canada for cancer brachytherapy. Current Oncology 2 (1): 6-13.

Bocchinfuso, W.P., and G.L. Hammond. 1994. Steroid-binding and dimerization domains of human sex hormone-binding globulin partially overlap: Steroids and Ca² + stabilize dimer formation. Biochemistry 33: 10622-10629.

Hammond, G.L., W.P. Bocchinfuso, M. Orava, C.L. Smith, A. van den Ende, and A. van Enk. 1994. Serum distribution of two oral contraceptive progestins: 3-ketodesogestrel and gestodene. Contraception 50: 301-318.

Hildebrand, C., W.P. Bocchinfuso, D. Dales, and G.L. Hammond. 1995. Resolution of the steroid-binding and dimerization domains of human sex hormone-binding globulin by expression in Escherichia coli. Biochemistry 34: 3231-3238.

Bautista, D.S., J.W. Xuan, C. Hota, A.F. Chambers, and J.F. Harris. 1994. Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. Journal of Biological Chemistry 269: 23280-23285.

Bautista, D.S., J.W. Xuan, C. Hota, A.F. Chambers, and J.F. Harris. 1994. Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. Journal of Biological Chemistry 269: 23280-23285.

Xuan, J.W., C. Hota, Y. Shigeyama, J.A. D'Errico, M.J. Somerman, and A.F. Chambers. 1995. Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions. Journal of Cellu lar Biochemistry 57: 680-690.

Jaffray, D., J.J. Battista, A. Fenster, and P. Munro. 1995. Monte Carlo Studies of x-ray energy absorption and quantum noise in megavoltage transmission radiography. Medical Physics 22 (7): 107-108.

O'Malley, F., Z. Saad, N. Kerkvlient, A.F. Chambers, K. Tonkin, U. Turnbull, and V. Bramwell. 1994. The predictive power of a combination of Ki 67, c-erb B2 and p53 in lymph node negative breast cancer. Modern Pathology 7: 94.

Khokha, R., J. Fata, and D.C. Martin. 1995. Utilization of transgenic mice in the study of matrix degrading proteinases and their inhibitors. Cancer Metastasis Review 14: 97-111.

Khokha, R., and P. Waterhouse. 1994. The role of tissue inhibitor of metalloproteinase-1 in specific aspects of cancer progression and reproduction. Journal of Neuro-Oncology 18: 123-127.

Koop, S., R. Khokha, E.E. Schmidt, I.C. MacDonald, V.L. Morris, A.F. Chambers, and A.C. Groom. 1994. Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Research 54: 4791-4797.

Koop, S., I.C. MacDonald, K. Luzzi, E.E. Schmidt, V.L. Morris, M. Grattan, R. Khokha, A.F. Chambers, and A.C. Groom. 1995. Fate of melanoma cells entering the microcirculation: Over 80% survive and extravasate. Cancer Research 55: 2520-25 23.

Morris, V.L., E.E. Schmidt, S. Koop, I.C. MacDonald, M. Grattan, R. Khokha, M.A. McLande, S. Niewiarowski, A.F. Chambers, and A.C. Groom. 1995. Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis. Experiment al Cell Research 219: 571-578.

Cai, L., J. Koropatnick, and M.G. Cherian. 1995. Metallothionein protects DNA from copper and iron-induced cleavage in vitro. Chemico-Biological Interactions 96: 143-155.

Cai, L., J. Koropatnick, and M.G. Cherian. 1995. Protection from metal-induced DNA damage by metallothionein in an in vitro system. Genetic Response to Metals. B. Sarkar. New York: Marcel Dekker Inc. 101-119.

Koropatnick, J. 1995. Molecular Methods in Renal Toxicology. Methods in Renal Toxicology. L. Lash, and R.K. Zalups. Boca Raton, Florida: CRC Press. 377-411.

Koropatnick, J., and M.G. Cherian. 1994. Metallothionein protein and mRNA in the toxic milk mouse. Biochemical Journal 304: 318-319.

Koropatnick, J., and J. DeMoor. 1995. Molecular Techniques in Metal Toxicology. Metal Toxicology. R.A. Goyer, K. Klaassen, and M. Waalkes. San Diego, CA: Academic Press. 111-139.

Koropatnick, J., and M.E.I. Leibbrandt. 1995. Effects of Metals on Gene Expression. Handbook of Experimental Pharmacology (Toxicology of Metals-Biochemical Aspects). 115 ed. R.A. Goyer, and M.G. Cherian. Berlin, New York: Springer-Verlag. 93-120.

Koropatnick, J., G.F. Stevenson, and M.G. Cherian. 1995. Copper accumulation, and metallothionein stability and developmental regulation, in the toxic milk mouse. Genetic Response to Metals. B. Sarkar. New York, NY: Marcel Dekker Inc. 443 -465.

Shiraishi, N., J.F. Hochadel, T.P. Coogan, J. Koropatnick, and M.P. Waalkes. 1995. Sensitivity to cadmium-induced genotoxicity in rat testicular cells is associated with minimal expression of the metallothionein gene. Toxicology and Applied P harmacology 130: 229-236.

Zalups, R., J. Fraser, and J. Koropatnick. 1995. Enhanced transcription of metallothionein genes in rat kidney: effect of uninephrectomy and compensatory renal growth. American Journal of Physiology 268: F643-F650.

Koropatnick, J., and M.E.I. Leibbrandt. 1995. Effects of Metals on Gene Expression. Handbook of Experimental Pharmacology (Toxicology of Metals-Biochemical Aspects). 115 ed. R.A. Goyer, and M.G. Cherian. Berlin, New York: Springer-Verlag. 93 -120.

Cairncross, J.G., D.R. Macdonald, S. Ludwin, D. Lee, T. Cascino, J. Buckner, D. Fulton, E. Dropcho, D. Stewart, C. Schold, N. Wainman, and E. Eisenhauer. 1994. Chemotherapy for anaplastic oligodendroglioma. Journal of Clinical Oncology 12: 2 013-2021.

Macdonald, D.R. 1994. Low-grade gliomas, mixed gliomas, and oligodendrogliomas. Seminars in Oncology 21: 236-248.

Macdonald, D.R. 1995. New therapies of primary CNS lymphomas and oligodendrogliomas. Journal of Neurooncology 24: 97-101.

Watling, C.J., D.H. Lee, D.R. Macdonald, and J.G. Cairncross. 1994. Corticosteroid-induced magnetic resonance imaging changes in patients with recurrent malignant glioma. Journal of Clinical Oncology 12: 1886-1889.

Watling, C.J., D.J. Van Meyel, D.A. Ramsay, D.R. Macdonald, and J.G. Cairncross. 1995. Loss of heterozygosity analysis of chromosomes 9, 10 and 17 in gliomas in familes. Canadian Journal of Neurological Sciences 22: 17-21.

Battista, J.J., R.B. Barnett, D.L.D. Mason, C.A. Plume, M.S. MacPherson, B. Fisher, and A.T. Porter. March 1995. New radioactive isotope developed in Canada for cancer brachytherapy. Current Oncology 2 (1): 6-13.

Koop, S., R. Khokha, E.E. Schmidt, I.C. MacDonald, V.L. Morris, A.F. Chambers, and A.C. Groom. 1994. Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Research 54: 47 91-4797.

Koop, S., I.C. MacDonald, K. Luzzi, E.E. Schmidt, V.L. Morris, M. Grattan, R. Khokha, A.F. Chambers, and A.C. Groom. 1995. Fate of melanoma cells entering the microcirculation: Over 80% survive and extravasate. Cancer Research 55: 2520-25 23.

Morris, V.L., S. Koop, I.C. MacDonald, E.E. Schmidt, M. Grattan, D. Percy, A.F. Chambers, and A.C. Groom. 1994. Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth. Clinical and Experimental Metastasis 12: 357-367.

Morris, V.L., E.E. Schmidt, S. Koop, I.C. MacDonald, M. Grattan, R. Khokha, M.A. McLande, S. Niewiarowski, A.F. Chambers, and A.C. Groom. 1995. Effects of the disintegrin eristostatin on individual steps of hematogenous metastasis. Experiment al Cell Research 219: 571-578.

Jaffray, D., J.J. Battista, A. Fenster, and P. Munro. 1995. Monte Carlo Studies of x-ray energy absorption and quantum noise in megavoltage transmission radiography. Medical Physics 22 (7): 107-108.

Munro, P. 1995. Portal imaging technology: past, present, and future. Seminars in Radiation Oncology 5 (2): 115-133.

Mymryk, J.S., and T.K. Archer. 1994. Detection of transcription factor binding in vivo using lambda exonuclease. Nucleic Acids Research 22: 4344-4345.

Mymryk, J.S., D. Berard, G.L. Hager, and T.K. Archer. 1995. MMTV chromatin in human breast cancer cells is constitutively hypersensitive and exhibits steroid hormone independent loading of transcription factors in vivo. Molecular and C ellular Biology 15: 26-34.

Nutt, C.L., J.F. Costello, L.L. Bambrick, D.B. Yarosh, L.E. Swinnen, A.F. Chambers, and J.G. Cairncross. 1995. 0⁶-Methylguanine-DNA methyltransferase in tumors and cells of the oligodendrocyte lineage. Canadian Journal of Neurological Sciences 22: 111-115.

McLellan, J., S. Sawchuk, H. Battusta, G.A. Sandison, and L.S. Papiez. 1994. A method for the calculation of electron energy-straggling spectra. Medical Physics 21 (3): 367-378.

Papiez, L.S., and J.J. Battista. 1994. Radiance and particle fluence. Medical Biology 39: 1053-1062.

Papiez, L.S., J. McLellan, G.A. Sandison, S. Sawchuk, X. Lu, and J.J. Battista. October 1994. Inclusion of energy straggling in a numerical method for electron dose calculation. Medical Physics 21 (10): 1591-1598.

Perera, F., F. Chisela, J. Engel, and V. Venkatesan. 1995. Method of localization and implantation of the lumpectomy site for high dose rate brachytherapy after conservative surgery for T1 and T2 breast cancer. International Journal of Radiation Oncology, Biology, Physics 31 (4): 959-965.

Battista, J.J., R.B. Barnett, D.L.D. Mason, C.A. Plume, M.S. MacPherson, B. Fisher, and A.T. Porter. March 1995. New radioactive isotope developed in Canada for cancer brachytherapy. Current Oncology 2 (1): 6-13.

Battista, J.J., R.B. Barnett, D.L.D. Mason, C.A. Plume, M.S. MacPherson, B. Fisher, and A.T. Porter. March 1995. New radioactive isotope developed in Canada for cancer brachytherapy. Current Oncology 2 (1): 6-13.

O'Malley, F., Z. Saad, N. Kerkvlient, A.F. Chambers, K. Tonkin, U. Turnbull, and V. Bramwell. 1994. The predictive power of a combination of Ki 67, c-erb B2 and p53 in lymph node negative breast cancer. Modern Pathology 7: 94.

Smith, A., I. Chin-Yee, and K. Howson-Jan. 1994. Peripheral blood stem cell transplantation versus bone marrow transplantation: re-evaluating eligibility criteria. Current Oncology 1 (3): 181-184.

Smith, A., A. Keating, N. Chao, J. Hester, D.R. Sutherland, A. Gee, J. Crown, Spitzer, H. Gluck, and V. Hamilton. 1994. Peripheral blood stem cell transplantation: Clinical, practical and economic considerations. Journal of Hematotherapy 3: 331-348.

O'Malley, F., Z. Saad, N. Kerkvlient, A.F. Chambers, K. Tonkin, U. Turnbull, and V. Bramwell. 1994. The predictive power of a combination of Ki 67, c-erb B2 and p53 in lymph node negative breast cancer. Modern Pathology 7: 94.

Tonkin, K., S. Gluck, M. Trudeau, and T. Vandenberg. 1995. Controversies in the treatment of metastatic breast cancer. Current Oncology 2: 87-91.

Watling, C.J., D.J. Van Meyel, D.A. Ramsay, D.R. Macdonald, and J.G. Cairncross. 1995. Loss of heterozygosity analysis of chromosomes 9, 10 and 17 in gliomas in familes. Canadian Journal of Neurological Sciences 22: 17-21.

Tonkin, K., S. Gluck, M. Trudeau, and T. Vandenberg. 1995. Controversies in the treatment of metastatic breast cancer. Current Oncology 2: 87-91.

Perera, F., F. Chisela, J. Engel, and V. Venkatesan. 1995. Method of localization and implantation of the lumpectomy site for high dose rate brachytherapy after conservative surgery for T1 and T2 breast cancer. International Journal of Radiation Oncology, Biology, Physics 31 (4): 959-965.

Bautista, D.S., J.W. Xuan, C. Hota, A.F. Chambers, and J.F. Harris. 1994. Inhibition of Arg-Gly-Asp (RGD)-mediated cell adhesion to osteopontin by a monoclonal antibody against osteopontin. Journal of Biological Chemistry 269: 23280-23285.

Xuan, J.W., C. Hota, Y. Shigeyama, J.A. D'Errico, M.J. Somerman, and A.F. Chambers. 1995. Site-directed mutagenesis of the arginine-glycine-aspartic acid sequence in osteopontin destroys cell adhesion and migration functions. Journal of Cellu lar Biochemistry 57: 680-690.