Leaders in Learning: Publications of Faculty & Staff


Physiology & Pharmacology 2002-2003



BEIER, F.

Beier, F., and P. Luvalle. 2002. The cyclin D1 and cyclin A genes are targets of activated PTH/PTHrP receptors in Jansen's metaphyseal chondrodysplasia. Molecular Endocrinology 16 (9): 2163-2173.

Luvalle, P., Q. Ma, and F. Beier. 2003. The role of activating transcription factor-2 in skeletal growth control. The Journal of Bone and Joint Surgery 85-A: 133-136.

Riemer, S., S. Gebhard, F. Beier, and E.v.d.M.K. Poschl. 2002. Role of c-fos in the regulation of type X collagen gene expression by PTH and PTHrP: localization of a PTH/PTHrP-responsive region in the human COL10A1 enhancer. Journal of Cellular Biochemistry 86: 688-699.



BEND, J.R.

Bailey, D.G., G.K. Dresser, and J.R. Bend. 2003. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice. Clinical Pharmacology Therapeutics 73: 529-537.

Seubert, J.M., A.J. Darmon, A. El-Kadi, S.J.A. D'Souza, and J.R. Bend. 2002. Apoptosis in murine hepatoma hepa 1c1c7 wild-type, C12, and C4 cells mediated by bilirubin. Molecular Pharmacology 62 (2): 257-264.



CHIDIAC, P.

Chakraborty, C., Y.P. Barbin, S. Chakrabarti, P. Chidiac, S.J. Dixon, and P.K. Lala. 2003. Endothelin-1 promotes migration and induces elevation of [Ca2+]i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line. Molecular and Cellular Endocrinology 201: 63-73.

Chidiac, P., and A.A. Roy. 2003. Activity, regulation, and intracellular localization of RGS proteins. Receptors and Channels 9: 135-147.

Cladman, W., and P. Chidiac. 2002. Characterization and comparison of RGS2 and RGS4 as GTPase-activating proteins for m2 muscarinic receptor-stimulated Gi. Molecular Pharmacology 62 (3): 654-659.



DIXON, S.J.

Chakraborty, C., Y.P. Barbin, S. Chakrabarti, P. Chidiac, S.J. Dixon, and P.K. Lala. 2003. Endothelin-1 promotes migration and induces elevation of [Ca2+]i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line. Molecular and Cellular Endocrinology 201: 63-73.

Ke, H.Z., H. Qi, A.F. Weidema, Q. Zhang, N. Panupinthu, D.T. Crawford, W.A. Grasser, V.M. Paralkar, M. Li, L.P. Audoly, C.A. Gabel, W.S.S. Jee, S.J. Dixon, S.M. Sims, and D.D. Thompson. 2003. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Molecular Endocrinology 17 (7): 1356-1367.

Komarova, S.V., M.F. Pilkington, A.F. Weidema, S.J. Dixon, and S.M. Sims. 2003. RANK ligand-induced elevation of cytosolic Ca2+ accelerates nuclear translocation of nuclear factor kB in osteoclasts. The Journal of Biological Chemistry 278 (10): 8286-8293.



FERGUSON, P.J.

Berg, R.W., P.J. Ferguson, M.D. Vincen, and J. Koropatnick. 2002. The means to an end to tumor cell resistance to chemotherapeutic. Current Drug Targets 3 (4): 297-309.



JONES, D.L.

Jones, D.L., A. Skanes, G.M. Guiraudon, C.M. Guiraudon, and D. Santoaianni. 2002. Atrial arrhythmias: localization and role for cryosurgery. International Journal of Bioelectromagnetism 2: 119-121.



KIDDER, G.M.

Gittens, J.E.I., A.A. Mhawi, D. Lidington, Y. Ouellette, and G.M. Kidder. 2003. Functional analysis of gap junctions in ovarian granulosa cells: distinct role for connexin43 in early stages of folliculogenesis. American Journal of Physiology and Cell Physiology 284: C880-C887.



LEUNG, L.S.

Leung, L.S., and C. Wu. 2003. Kindling suppresses primed-burst induced long-term potentiation in hippocampal CA1. Neurophysiology, Basic and Clinical 14 (2): 1-4.

Liebregts, M.T., R.S. McLachlan, and L.S. Leung. 2002. Hyperthermia induces age-dependent changes in rat hippocampal excitability. Annals of Neurology 52: 318-326.

Stewart, L., and L.S. Leung. 2003. Temporal lobe seizures alter the amplitude and timing of behavioral rhythms. Epilepsy and Behavior 4 (2): 153-160.

Wu, K., and L.S. Leung. 2003. Increased dendritic excitability in hippocampal CA1 in vivo in the kainic acid model of temporal lobe epilepsy: a study using current source density analysis. Neuroscience 116: 599-616.



RYLETT, R.J.

Bhattacharya, M., P.H. Anborgh, A.V. Babwah, L.B. Dale, T. Dobransky, J.L. Benovic, R.D. Feldman, J.M. Verdi, R.J. Rylett, and S.S. Ferguson. 2002. b-arrestins regulate a Ral-GDS effector pathway that mediates cytoskeletal reorganization. Nature Cell Biology 4 (8): 547-555.

Dobransky, T., D. Brewer, G. Lajoie, and R.J. Rylett. 2002. Phosphorylation of 69-kDa choline acetyltransferase at threonine 456 in response to amyloid-b peptide 1-42. Journal of Biological Chemistry 278 (8): 5883-93.

Gill, S.K., M. Bhattacharya, S.S. Ferguson, and R.J. Rylett. 2003. Identification of a novel nuclear localization signal common to 69- and 82-kDa human choline acetyltransferase. Journal of Biological Chemistry 278 (2): 20217-20224.



SIMS, S.

Deshpande, M.A., J. Wang, H.G. Preiksaitis, L.G. Laurier, and S.M. Sims. 2002. Characterization of a voltage-dependent Na+ current in human esophageal smooth muscle. American Journal of Physiology Cell Physiology 283: C1045-C1055.

Karkanis, T., L. DeYoung, G.B. Brock, and S.M. Sims. 2003. Ca2+-activated C1- channels in corpus cavernosum smooth muscle: a novel mechanism for control of penile erection. Journal of Applied Physiology 94: 301-313.

Karkanis, T., S. Li, J.G. Pickering, and S.M. Sims. 2003. Plasticity of Kir channels in human smooth muscle cells from internal thoracic artery. American Journal of Physiology Heart Circulation Physiology 284 (2): H2325-H2334.

Ke, H.Z., H. Qi, A.F. Weidema, Q. Zhang, N. Panupinthu, D.T. Crawford, W.A. Grasser, V.M. Paralkar, M. Li, L.P. Audoly, C.A. Gabel, W.S.S. Jee, S.J. Dixon, S.M. Sims, and D.D. Thompson. 2003. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Molecular Endocrinology 17 (7): 1356-1367.

Komarova, S.V., M.F. Pilkington, A.F. Weidema, S.J. Dixon, and S.M. Sims. 2003. RANK ligand-induced elevation of cytosolic Ca2+ accelerates nuclear translocation of nuclear factor kB in osteoclasts. The Journal of Biological Chemistry 278 (10): 8286-8293.

Wang J., L.G. Laurier, S.M. Sims, and H.G. Preiksaitis. 2003. Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle. American Journal of Physiology Gastrointestinal Liver Physiology 284 (6): G1074-G1083.



TEPPERMAN, B.L.

Chang, Q., and B.L. Tepperman. 2003. Effect of selective PKC isoform activation and inhibition on TNF-a-induced injury and apoptosis in human intestinal epithelial cells. British Journal of Pharmacology 140: 41-52.



WAGNER, G.F.

Filvaroff, E.H., S. Guillet, C. Zlot, M. Bao, G. Ingle, H. Steinmetz, J. Hoeffel, S. Bunting, J. Ross, R.A.D. Carano, L. Powell-Braxton, G.F. Wagner, R. Eckert, M.E. Gerritsen, and D.M. French. 2002. Stanniocalcin 1 alters muscle and bone structure and function in transgenic mice. Endocrinology 143 (9): 3681-3690.



WILSON, J.X.

Chan, T.S., S. Teng, J.X. Wilson, G. Galati, K. Sumsallah, and P.J. O'Brien. 2002. Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1 (NQO1). Journal of Free Radical Research 36 (4): 421-427.

Daskalopoulos, R., J. Korcok, L. Tao, and J.X. Wilson. 2002. Accumulation of intracellular ascorbate from dehydroascorbic acid by astrocytes is decreased after oxidative stress and restored by propofol. GLIA 39: 124-132.

Galati, G., O. Sabzevari, J.X. Wilson, and P.J. O'Brien. 2002. Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology 177: 91-104.

Gelb, A.W., N.A. Bayona, J.X. Wilson, and D.F. Cechetto. 2002. Propofol anesthesia compared to awake reduces infarct size in rats. Anesthesiology 96: 1183-90.

Korcok, J., F. Wu, K. Tyml, R.R. Hammond, and J.X. Wilson. 2002. Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition. Journal of Neurochemistry 81: 185-193.

Wilson, J.X. 2002. The physiological role of dehydroascorbic acid. FEBS Letters 527: 5-9.

Wilson, J.X., and A.W. Gelb. 2002. Free radicals, antioxidants, and neurologic injury: possible relationship to cerebral protection by anesthetics. Journal of Neurosurigcal Anesthesiology 14 (1): 66-79.

Wilson, J.X., and G.B. Young. 2003. Sepsis-associated encephalopathy: evolving concepts. Canadian Journal of Neurological Science 30: 98-105.

Wu, F., K. Tyml, and J.X. Wilson. 2002. Ascorbate inhibits iNOS expression in endotoxin- and IFNg-stimulated rat skeletal muscle endothelial cells. FEBS Letters 520: 122-126.

Wu, F., J.X. Wilson, and K. Tyml. 2003. Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice. American Journal of Physiology 285: R50-R56.