Leaders in Learning: Publications of Faculty & Staff
Pharmacology & Toxicology 2001-2002
Offman, E.M., D.J. Freeman, G.K. Dresser, C. Munoz, J.R. Bend, and D.G. Bailey. 2001. Red wine-cisapride interaction: Comparison with grapefruit juice. Clinical Pharmacology & Therapeutics 70: 17-23.
Seubert, J.M., Signal C.J., and J.R. Bend. 2002. Acute sodium arsenite administration induces pulmonary CYP1A1 mRNA, protein and activity in the rat. Journal of Biochemical and Molecular Toxicology 16 (2): 84-95.
Seubert, J.M., C.D. Webb, and J.R. Bend. 2002. Acute sodium arsenite
treatment induces Cyp2a5 but not Cyp1a1 in
the C57B1/6 mouse in a tissue (kidney) selective manner. Journal of
Biochemical and Molecular Toxicology 16 (2): 96-106.
Chidiac, P. 2002. Consideration in the evaluation of inverse agonism and protein agonism at G-protein coupled receptors. Methods in Enzymology 343: 3-16.
McKinnon, T., C. Chakraborty, L.M. Gleeson, P. Chidiac, and P.K. Lala. 2001. Stimulation of human extravillous trophoblast migration by IGF-II Is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK. The Journal of Clinical Endocrinology & Metabolism 86 (8): 3665-3674.
Santhanagopal, A., P. Chidiac, W.C. Horne, R. Baron, and S.J. Dixon.
2001. Calcitonin (CT) rapidly increases Na+/H+ exchange
and metabolic acid production: Effects mediated selectively by the C1a
CT Receptor Isoform. Endocrinology 142 (10): 4401-4413.
D'Souza, S.J.A., A. Vespa, S. Murkherjee, A. Maher, A. Pajak, and
L. Dagnino. 2002. E2F-1 Is essential for normal epidermal wound repair.
Journal of Biological Chemistry 277 (12): 10626-10632.
Berg, R.W., M. Werner, P.J. Ferguson, C. POstenka, M. Vincent, D.J. Koropatnick, and E. Behrend. 2001. Tumor growth inhibition in vivo and G2/M cell cycle arrest induced by antisense oligodeoxynucleotide targeting thymidylate synthase. The Journal of Pharmacology and Experimental Therapeutics 298 (2): 477-484.
Ferguson, P.J., J.M. DeMoor, M.D. Vincent, and J. Koropatnick.
2001. Antisense-induced down-regulation of thymidylate synthase and enhanced
cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells. British Journal
of Pharmacology 134 (7): 1437-1446.
Avvakumov, G.V., I. Grishkovskaya, Y.A. Muller, and G.L. Hammond. 2001. Resolution of the human sex hormone-binding globulin dimer interface and evidence for two steroid-binding sites per homodimer. Journal of Biological Chemistry 276: 34453-334457.
Grishkovskaya, I., G.V. Avvakumov, G.L. Hammond, and Y.A. Muller. 2002. Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site. Journal of Molecular Biology 318: 621-626.
Hammond, G.L., T. Rabe, and J.D. Wagner. 2001. Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy. American Journal of Obstetrics and Gynaecology 185: S24-S31.
Hovegeen, K.N., P. Cousin, M. Pugeat, D. Dewailly, B. Soudan, and G.L. Hammond. 2002. Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction. The Journal of Clinical Investigation 109 (7): 973-981.
Hovgeveen, K.N., M. Talikka, and G.L. Hammond. 2001. Human sex hormone-binding globulin promoter activity is influenced by a (TAAAA)n repeat element within an Alu sequence. Journal of Biological Chemistry 276: 36383-36390.
Raineri, M., M.G. Catalano, G.L. Hammond, G.V. Avvakumov, R. Frairia,
and N. Fortunati. 2002. O-Gylcosylation of human sex hormone-binding
globulin is essential for inhibition of estradiol-induced MCF-7 breast
cancer cell proliferation. Molecular and Cellular Endocrinology
Vyas, S., B. Ahmadi, and J.R. Hammond. 2002. Complex effects
of sulfhydryl reagents on ligand interactions with nucleoside transporters:
evidence for multiple populations of ENT1 transporters with differential
sensitivities to N-ethylmaleimide. Archives of Biochemistry and
Biophysics 403: 92-102.
Chakrabarti, S., S. Chen, T. Evans, and M. Karmazyn. 2001. Endothelins in the microvasculature and heart in diabetes. Advances in Experimental Medicine and Biology 498: 97-108.
Chen, L., X.T. Gan, J.V. Haist, Q. Feng, X. Lu, S. Chakrabati, and M. Karmazyn. 2001. Attentuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the NA+-H+ exchange inhibitor cariporide. The Journal of Pharmacology and Experimental Therapeutics 298 (2): 469-476.
Daskalopoulos, R., J. Korcok, P. Farhangkhgoee, M. Karmazyn, A.W. Gelb, and J.X. Wilson. 2001. Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress. Anesthesia and Analgesia 93 (5): 1199-1204.
Gazmuri, R.J., Ayoub I.M., J.D. Kolarova, and M. Karmazyn. 2002. Myocardial protection during ventricular fibrillation by inhibition of the sodium-hydrogen exchanger isoform-1. Critical Care Medicine 30 (4 Suppl): S166-S171.
Holmes, M.E., Mwanjewe J., S.E. Samson, J.V. Haist, J.X. Wilson, S.J. Dixon, M. Karmazyn, and A.K. Grover. 2002. Dehydroascorbic acid uptake by cornary artery smooth muscle: effect of intracellular acidification. Biochemical Journal 362: 507-512.
Karmazyn, M. 2001. Role of sodium-hydrogen exchange in cardiac hypertrophy and heart failure: a novel and promising therapeutic target. Basic Research in Cardiology 96 (4): 325-328.
Paroo, Z., J.V. Haist, M. Karmazyn, and E.G. Noble. 2002. Exercise improves postischemic cardiac function in males but not females. Circulation Research 90 (8): 911-917.
Paroo, Z., M.J. Meredith, M. Locke, J. Haist, M. Karmazyn, and E.G.
Noble. 2002. Redox signaling of cardiac HSF1 DNA binding. American
Journal of Physiology. Cell Physiology 283 (2): C404-C411.
Baechtold, F., J.A. Scott, M. Markert, S. Mehta, D.G. McCormack, F. Anglada, D. Galaud, M. Vaglio, B. Waeber, and F. Feihl. 2001. Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture? Shock 16 (2): 137-142.
Dennie, C.J., J.P. Veinot, D.G. McCormack, and F.D. Rubens. 2002. Intimal sarcoma of the pulmonary arteries seen as a mosaic pattern of lung attenuation on high-resolution CT. American Journal of Roentgenology 178 (5): 1208-1210.
Razavi, H.M., R. Werhun, J.A. Scott, S. Weicker, L.F. Wang, D.G. McCormack, and S. Mehta. 2002. Effects of inhaled nitric oxide in a mouse model of sepsis-induced acute lung injury. Critical Care Medicine 30 (4): 868-873.
Weicker, S., T.A. Karachi, J.A. Scott, D.G. McCormack, and S. Mehta. 2001. Noninvasive measurement of exhaled nitric oxide in a spontaneously breathing mouse. American Journal of Respiratory Care Medicine 163: 1113-1116.
Yaghi, A., C.D. Webb, J.A. Scott, S. Mehta, J.R. Bend, and D.G. McCormack.
2001. Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2
metabolites contribute to the pulmonary vascular hyporeactivity in rats
with acute Pseudomonas pneumonia. The Journal of Pharmacology
and Experimental Therapeutics 297 (2): 479-488.
Philp, R.B. 2001. Effects of experimental manipulation of Ph and salinity on Cd2+ uptake by the sponge Microciona prolifera and on sponge cell aggregation induced by Ca2+ and Cd2+. Archives of Environmental Contamination and Toxicology 41: 282-288.