Graduate Courses
The focus of graduate student training in our program is on learning to develop and carry out high-quality research projects. This is supplemented with course work that assists the student with acquiring skills in scientific communication, critical thinking and iassessment and ntegration of informaiton form the cellular-molecular to translational level. All students are expected to attend and participate in the Department Seminar Series during their course of study, in order to broaden and strengthen their knowledge of our disciplines.
Required M.Sc. Courses
Physiology Program
Physiology 9551 Communications and Critical Thinking
|
Physiology and Pharmacology Communications and Critical Thinking
Description: required course for 1st year M.Sc. and Ph.D. students in both the Physiology and the Pharmacology Graduate Programs. If Ph.D. students have transferred to this degree program from a Physiology or Pharmacology M.Sc. graduate program and have already completed this course then they are not required to complete the course again. The overall goal of the course is to fill the graduate student "toolkit" so that the graduate student is prepared to conduct their thesis project.
Course Objectives:
- To provide an overview of the expectations and standards required to complete a Physiology or Pharmacology MSc and PhD degree.
- To present professionalism, "student code of conduct", "supervisory code of conduct" research integrity and ethics topics
- To introduce lab safety and animal care protocols to all new graduate students
- To introduce the advisory committee meeting and its role in supporting progress over the graduate training period
- To foster communication and interaction between students and PIs within the Physiology and Pharmacology Graduate Programs.
- To allow students to develop skills in scientific oral presentation and critically analyzing journal articles.
- To allow students to develop skills in scientific writing including research proposals, journal articles and thesis.
- To provide students with an introduction to experimental design and data analysis.
Components of the Course:
CCT will be a 1 credit, two term course with one 2-hour session of classroom time/week. The time commitment will vary depending on the number of students within the program. The evaluation for this course will be based on four criteria:
- Oral presentation and critique of a recent journal article in their field (25%)
- Presentation of progress in your project in preparation for your first full advisory committee meeting (30%).
- a written 5 page grant proposal outlining your research project proposal (30%).
- Participation in all student presentations and mandatory attendance at all lectures in the course (15%)
Instructors:
Dr. A. Watson. Email: awatson@schulich.uwo.ca
Dr. L. Dagnino. Email: ldagnino@uwo.ca
Dr. J. Hammond. Email: james.hammond@schulich.uwo.ca
Dr. D. Freeman. Email: dfreeman@uwo.ca
Dr. L. Coolen. Email: Lique.Coolen@schulich.uwo.ca
Day and Time: 9:30 -11:30 am every Friday Morning Starting September 18th
Place: Room University College room 222
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Physiology 9590 M.Sc. Thesis
|
Students are automatically enrolled when accepted into the Master's program in the Department of Physiology and Pharmacology.
Thesis Information: Guidelines for the preparation and examination of MSc thesis is provided by the Faculty of Graduate Studies.
|
Pharmacology & Toxicology Program
Pharmacology 9551 Communications and Critical Thinking
|
Physiology and Pharmacology Communications and Critical Thinking
Description: required course for 1st year M.Sc. and Ph.D. students in both the Physiology and the Pharmacology Graduate Programs. If Ph.D. students have transferred to this degree program from a Physiology or Pharmacology M.Sc. graduate program and have already completed this course then they are not required to complete the course again. The overall goal of the course is to fill the graduate student "toolkit" so that the graduate student is prepared to conduct their thesis project.
Course Objectives:
- To provide an overview of the expectations and standards required to complete a Physiology or Pharmacology MSc and PhD degree.
- To present professionalism, "student code of conduct", "supervisory code of conduct" research integrity and ethics topics
- To introduce lab safety and animal care protocols to all new graduate students
- To introduce the advisory committee meeting and its role in supporting progress over the graduate training period
- To foster communication and interaction between students and PIs within the Physiology and Pharmacology Graduate Programs.
- To allow students to develop skills in scientific oral presentation and critically analyzing journal articles.
- To allow students to develop skills in scientific writing including research proposals, journal articles and thesis.
- To provide students with an introduction to experimental design and data analysis.
Components of the Course:
CCT will be a 1 credit, two term course with one 2-hour session of classroom time/week. The time commitment will vary depending on the number of students within the program. The evaluation for this course will be based on four criteria:
- Oral presentation and critique of a recent journal article in their field (25%)
- Presentation of progress in your project in preparation for your first full advisory committee meeting (30%).
- a written 5 page grant proposal outlining your research project proposal (30%).
- Participation in all student presentations and mandatory attendance at all lectures in the course (15%)
Instructors:
Dr. A. Watson. Email: awatson@schulich.uwo.ca
Dr. L. Dagnino. Email: ldagnino@uwo.ca
Dr. J. Hammond. Email: james.hammond@schulich.uwo.ca
Dr. D. Freeman. Email: dfreeman@uwo.ca
Dr. L. Coolen. Email: Lique.Coolen@schulich.uwo.ca
Day and Time: 9:30 -11:30 am every Friday Morning Starting September 18th
Place: Room University College room 222
|
Pharmacology 9590 M.Sc. Thesis
|
Students are automatically enrolled when accepted into the Master's program in the Department of Physiology and Pharmacology.
Thesis Information: Guidelines for the preparation and examination of MSc thesis is provided by the Faculty of Graduate Studies.
|
Required Ph.D. Courses
Physiology Program
Physiology 9551 Communications and Critical Thinking
|
Physiology and Pharmacology Communications and Critical Thinking
Description: required course for 1st year M.Sc. and Ph.D. students in both the Physiology and the Pharmacology Graduate Programs. If Ph.D. students have transferred to this degree program from a Physiology or Pharmacology M.Sc. graduate program and have already completed this course then they are not required to complete the course again. The overall goal of the course is to fill the graduate student "toolkit" so that the graduate student is prepared to conduct their thesis project.
Course Objectives:
- To provide an overview of the expectations and standards required to complete a Physiology or Pharmacology MSc and PhD degree.
- To present professionalism, "student code of conduct", "supervisory code of conduct" research integrity and ethics topics
- To introduce lab safety and animal care protocols to all new graduate students
- To introduce the advisory committee meeting and its role in supporting progress over the graduate training period
- To foster communication and interaction between students and PIs within the Physiology and Pharmacology Graduate Programs.
- To allow students to develop skills in scientific oral presentation and critically analyzing journal articles.
- To allow students to develop skills in scientific writing including research proposals, journal articles and thesis.
- To provide students with an introduction to experimental design and data analysis.
Components of the Course:
CCT will be a 1 credit, two term course with one 2-hour session of classroom time/week. The time commitment will vary depending on the number of students within the program. The evaluation for this course will be based on four criteria:
- Oral presentation and critique of a recent journal article in their field (25%)
- Presentation of progress in your project in preparation for your first full advisory committee meeting (30%).
- a written 5 page grant proposal outlining your research project proposal (30%).
- Participation in all student presentations and mandatory attendance at all lectures in the course (15%)
Instructors:
Dr. A. Watson. Email: awatson@schulich.uwo.ca
Dr. L. Dagnino. Email: ldagnino@uwo.ca
Dr. J. Hammond. Email: james.hammond@schulich.uwo.ca
Dr. D. Freeman. Email: dfreeman@uwo.ca
Dr. L. Coolen. Email: Lique.Coolen@schulich.uwo.ca
Day and Time: 9:30 -11:30 am every Friday Morning Starting September 18th
Place: Room University College room 222
|
- Plus additional eligible 0.50 course (A, B or C):
A) 9553 Translational Research (Bench to Bedside)
|
The objective of this course is familiarize students with the approaches and issues associated with taking a basic science discovery through to effective therapeutic use in patient populations. An additional objective is to expand the scope of students' understanding of how their graduate research project fits into the ‘bigger picture' of the advancement of science and medicine.
The course will consist of 3 three week modules focused on the current or historical development of a therapeutic regimen involving:
- a traditional small molecule drug
- a cell based therapy
- a therapy involving a protein or antibody
Each of these development paths has different issues associated with it and incorporates different areas of research. This will be followed by a 4th module in which students make a formal presentation on how their own thesis studies might be extended into the clinical/applied realm. Most of the course will involve small group discussion sessions and student presentations.
|
B) 9555 Drug Development
|
COURSE INFORMATION: The Drug Development course consists of 10 sessions, each 90 minutes long.
The purpose of the course is to introduce the student to scientific, regulatory and financial aspects of drug development in Canada and the US. The course will conclude with a discussion of practical concerns related to drug development and approval in an industry setting.
LECTURES: Tuesdays 9:30-11:00 January 8 - March 11, 2008
PREREQUISITES
INSTRUCTORS
|
Course Manager
|
|
David Freeman PhD
|
|
|
Instructors
|
|
|
Mike Rieder MD.PhD.
|
|
|
David Bailey PhD.
|
|
|
David Knoppert BSc.Pharm. MSc.
|
|
|
Doreen Matsui MD.
|
|
|
George Dresser MD. PhD.
|
|
|
Richard Kim MD.
|
|
EVALUATION: Final Exam 100%
FINAL EXAMINATION: There will be one final examination in the Drug Development section. It will represent 100% of the final mark and will take the form of short-answer questions covering material presented by faculty.
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
|
C) 9557 Pharmacokinetics and Drug Disposition
|
COURSE INFORMATION: The purpose of the course is to introduce the student to quantitative analysis of drug disposition and relevance to clinical pharmacology and drug discovery/development. In addition to the mathematical basis for drug disposition, the course also includes material on basic chemical, biochemical, and physiological processes that determine pharmacokinetics. Previous background in pharmacokinetics is unnecessary but basic pharmacology/toxicology knowledge and basic mathematical skills are required. The course consists of 10 didactic sessions and a 2 hr practical session on computer-based pharmacokinetic analysis and simulation. Problem sets will be assigned weekly and students will give 2 presentations on topics related to pharmacokinetics and clinical pharmacology.
INSTRUCTORS
Rommel Tirona, PhD
LECTURES
Mondays 12-2pm. Beginning Jan. 11, 2010 in Room C3-170 (Boardroom) LHSC-University Hospital, then subsequent Mondays in Auditorium D, LHSC-University Hospital.
EVALUATION: Problem sets (30%) and two presentations (35% each).
|
Physiology 9620 Current Topics in Physiology
(Grant Writing)
|
This course is completed by students within 18 months of entering the Physiology Ph.D. program. Failure to complete Physiology 620 and the comprehensive examination (Physiology 630) by 18 months from the beginning of the Ph.D. program will result in withdrawal from the Ph.D. program.
The objective is to prepare a grant proposal based on the topic of the Ph.D. thesis research. The proposal is to be of a format and quality that could be submitted to the Canadian Institutes of Health Research. Students complete the Research module of the CIHR application, which is available at http://www.cihr-irsc.gc.ca/.
Students may consult the course manager to review the nature of the exercise and obtain recent publications concerning preparation of successful applications. Supervisors may provide advice on content, style and layout, but should not participate in the writing of the proposal.
The proposal is reviewed by at least two members of faculty. The evaluation provides:
i) The type of critique usually provided by a member of a grants committee.
ii) Suggestions for improving the quality of the application.
INSTRUCTORS
|
Course Manager
|
|
Dr. Marc Tini
|
SDRI 220B; Tel: 519-850-2942;
|
|
|
Fax: 519-661-3827
|
EVALUATION: Producing an application that would achieve an acceptable rating (at least 3.0, on a scale of 0-4.9) in a CIHR competition meets the course requirements.
INSTRUCTIONAL INFORMATION: Advice on grant writing is contained in the article by Jacob Kraicer, entitled " The Art of Grantmanship".
|
Ph.D. Comprehensive Examination (requirement for Ph.D. program)
|
The comprehensive examination for Ph.D. students in the Department of Physiology and Pharmacology is designed to focus not only on the student's particular area of interest, but also to include studies in related areas deemed to be appropriate by the student's Supervisor(s), Graduate Advisory Committee and Graduate Studies Committee.
The comprehensive examination is administered by an ad hoc Examination Committee, established by the Graduate Studies Committee, consisting of three examiners who are experts in the identified areas. The Chair of the Examination Committee is normally the Graduate Studies Committee Representative on the student's Advisory Committee, but is not an examiner. Members of the Advisory Committee, and extra-departmental faculty, but not the supervisor, may serve on the examination committee.
The student, supervisor and the Advisory Committee prepare a list of topics related to the thesis, suggest examiners, and define an approximate date for the exam. Suggested examiners can include Advisory Committee members provided they are not co-authors on papers by the candidate. The Graduate Studies Committee may modify this list of topics and/or examiners, and is responsible for final approval of this list. The student is informed of the list of topics and the examiners at least four weeks prior to the examination. The examination will normally not be given in the summer months. The grant application, prepared for Physiology 9620 or Pharmacology 9620 defines the general scope of the comprehensive examination.
When a student is registered in a specialty interdisciplinary program, one of the tutor-examiners will normally be a core faculty member from that program.
The examiners' assessment will be based on the ability of the candidate:
- To demonstrate a knowledge of general concepts and principles of the discipline of study, and their application to scientific investigation
- To answer questions of fact in the specified subdisciplines
- To be aware of the historical developments and recent advances in the specified subdisciplines
- To be familiar with current research methods and use factual information to appropriately address novel problems in his/her own and related fields.
- The examination is usually two to three hours in duration and is normally chaired by the Graduate Studies Committee Representative on the student's Advisory Committee.
- Only members of the examination committee are permitted to ask questions; other faculty may attend but do not participate.
- The candidate's supervisor is encouraged to be present for the oral examination but does not participate in questioning or balloting.
- In the unexpected absence of an examiner for the oral component of the comprehensive due to illness or unforeseen circumstances, the exam will proceed with the two remaining examiners. In this case, the Chair of the examination will cast the deciding vote, if necessary.
Number of Attempts
A student may be permitted two attempts at the examination. After two unsuccessful attempts, the student will meet with the Advisory Committee to determine a course of action, which will normally involve withdrawal from the graduate program.
Procedure:
- After introductions, the student will be asked to leave the room, at which time the format of questions (e.g., two rounds of questions, first ~15 min, second ~10 min) and the order of examiners shall be determined.
- The student will be invited back into the room and the examination will begin.
- The chair will ensure that the time constraints are followed.
- At the conclusion of the examination, the candidate will leave the room, and the Chair will invite discussion by the examiners of the student's performance, prior to calling a vote.
- Votes on performance on the examination are collected by written ballots from members of the examination committee. A simple majority decides the outcome of the examination.
- Following the vote, the student's supervisor may comment.
The following outcomes are possible:
1) Pass
2) Failure with the recommendation that the exam be re-taken.
3) Failure. (The student's Advisory Committee shall meet to determine whether student should be required to withdraw from the program.)
- At the conclusion of the examiners' deliberations, the Chair will verbally inform the student of the outcome and transmit any comments the examiners might suggest.
- The Chair of the examining committee will provide the student and advisor with a copy of the examination report from the Chair, stating the results of the examination and, where appropriate, comments on the student's performance and recommendations, if applicable (see form on following page).
- Should it be necessary, the second attempt (and final opportunity) should take place no longer than one month after the first examination.
DEPARTMENT OF PHYSIOLOGY AND PHARMACOLOGY
Ph.D. Comprehensive Examination
Date:
Candidate:
Examining Committee:
Chair:
Examiners:
Comments:
Outcome/Grade:
Recommendations:
Date: _________________________ ___________________________________
Examination Committee Chairman
|
Ph.D. Research Seminar (requirement for Ph.D. program)
|
The Ph.D. research seminar must be completed during the last year of the Ph.D. program. The Ph.D. seminar is normally given as a Departmental seminar within our seminar series. The research seminar is based on thesis work.
Suggested Seminar Content
Scientific Content
Appropriateness of the literature review
Hypothesis - and is it based logically on literature?
Rationale
Methods, including statistical analysis
Proposed experiments and expected results
Results and their interpretation, where appropriate
Presentation Style
- Organization
- Appropriateness of level of explanation
- Use of overheads/slides
Knowledge of area
- Indicated by response to questions
|
Physiology 9690 Ph.D. Thesis
|
Students are automatically enrolled when accepted into the Ph.D. program in the Department of Physiology and Pharmacology.
Thesis Information: Guidelines for the preparation and examination of Ph.D. thesis is provided by the Faculty of Graduate Studies.
|
Pharmacology & Toxicology Program
Pharmacology 9551 Communications and Critical Thinking
|
Physiology and Pharmacology Communications and Critical Thinking
Description: required course for 1st year M.Sc. and Ph.D. students in both the Physiology and the Pharmacology Graduate Programs. If Ph.D. students have transferred to this degree program from a Physiology or Pharmacology M.Sc. graduate program and have already completed this course then they are not required to complete the course again. The overall goal of the course is to fill the graduate student "toolkit" so that the graduate student is prepared to conduct their thesis project.
Course Objectives:
- To provide an overview of the expectations and standards required to complete a Physiology or Pharmacology MSc and PhD degree.
- To present professionalism, "student code of conduct", "supervisory code of conduct" research integrity and ethics topics
- To introduce lab safety and animal care protocols to all new graduate students
- To introduce the advisory committee meeting and its role in supporting progress over the graduate training period
- To foster communication and interaction between students and PIs within the Physiology and Pharmacology Graduate Programs.
- To allow students to develop skills in scientific oral presentation and critically analyzing journal articles.
- To allow students to develop skills in scientific writing including research proposals, journal articles and thesis.
- To provide students with an introduction to experimental design and data analysis.
Components of the Course:
CCT will be a 1 credit, two term course with one 2-hour session of classroom time/week. The time commitment will vary depending on the number of students within the program. The evaluation for this course will be based on four criteria:
- Oral presentation and critique of a recent journal article in their field (25%)
- Presentation of progress in your project in preparation for your first full advisory committee meeting (30%).
- a written 5 page grant proposal outlining your research project proposal (30%).
- Participation in all student presentations and mandatory attendance at all lectures in the course (15%)
Instructors:
Dr. A. Watson. Email: awatson@schulich.uwo.ca
Dr. L. Dagnino. Email: ldagnino@uwo.ca
Dr. J. Hammond. Email: james.hammond@schulich.uwo.ca
Dr. D. Freeman. Email: dfreeman@uwo.ca
Dr. L. Coolen. Email: Lique.Coolen@schulich.uwo.ca
|
- Plus additional eligible 0.50 course (A, B or C):
A) 9553 Translational Research (Bench to Bedside)
|
The objective of this course is familiarize students with the approaches and issues associated with taking a basic science discovery through to effective therapeutic use in patient populations. An additional objective is to expand the scope of students' understanding of how their graduate research project fits into the ‘bigger picture' of the advancement of science and medicine.
The course will consist of 3 three week modules focused on the current or historical development of a therapeutic regimen involving:
- a traditional small molecule drug
- a cell based therapy
- a therapy involving a protein or antibody
Each of these development paths has different issues associated with it and incorporates different areas of research. This will be followed by a 4th module in which students make a formal presentation on how their own thesis studies might be extended into the clinical/applied realm. Most of the course will involve small group discussion sessions and student presentations.
|
B) 9555 Drug Development
|
COURSE INFORMATION: The Drug Development course consists of 10 sessions, each 90 minutes long.
The purpose of the course is to introduce the student to scientific, regulatory and financial aspects of drug development in Canada and the US. The course will conclude with a discussion of practical concerns related to drug development and approval in an industry setting.
LECTURES: Tuesdays 9:30-11:00 January 8 - March 11, 2008
PREREQUISITES
INSTRUCTORS
|
Course Manager
|
|
David Freeman PhD
|
|
|
Instructors
|
|
|
Mike Rieder MD.PhD.
|
|
|
David Bailey PhD.
|
|
|
David Knoppert BSc.Pharm. MSc.
|
|
|
Doreen Matsui MD.
|
|
|
George Dresser MD. PhD.
|
|
|
Richard Kim MD.
|
|
EVALUATION: Final Exam 100%
FINAL EXAMINATION: There will be one final examination in the Drug Development section. It will represent 100% of the final mark and will take the form of short-answer questions covering material presented by faculty.
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
|
C) 9557 Pharmacokinetics and Drug Disposition
|
COURSE INFORMATION: The purpose of the course is to introduce the student to quantitative analysis of drug disposition and relevance to clinical pharmacology and drug discovery/development. In addition to the mathematical basis for drug disposition, the course also includes material on basic chemical, biochemical, and physiological processes that determine pharmacokinetics. Previous background in pharmacokinetics is unnecessary but basic pharmacology/toxicology knowledge and basic mathematical skills are required. The course consists of 10 didactic sessions and a 2 hr practical session on computer-based pharmacokinetic analysis and simulation. Problem sets will be assigned weekly and students will give 2 presentations on topics related to pharmacokinetics and clinical pharmacology.
INSTRUCTORS
Rommel Tirona, PhD
LECTURES
Mondays 12-2pm. Beginning Jan. 11, 2010 in Room C3-170 (Boardroom) LHSC-University Hospital, then subsequent Mondays in Auditorium D, LHSC-University Hospital.
EVALUATION: Problem sets (30%) and two presentations (35% each).
|
Pharmacology 9620 Current Topics in Pharmacology
(Grant writing)
|
This course is completed by students within 18 months of entering the Physiology Ph.D. program. Failure to complete Pharmacology 620 and the comprehensive examination (Pharmacology 614) by 18 months from the beginning of the Ph.D. program will result in withdrawal from the Ph.D. program.
The objective is to prepare a grant proposal based on the topic of the Ph.D. thesis research. The proposal is to be of a format and quality that could be submitted to the Canadian Institutes of Health Research. Students complete the Research module of the CIHR application, which is available at http://www.cihr-irsc.gc.ca/.
Students may consult the course manager to review the nature of the exercise and obtain recent publications concerning preparation of successful applications. Supervisors may provide advice on content, style and layout, but should not participate in the writing of the proposal.
The proposal is reviewed by at least two members of faculty. The evaluation provides:
i) The type of critique usually provided by a member of a grants committee.
ii) Suggestions for improving the quality of the application.
INSTRUCTORS
|
Course Manager
|
|
Dr. Marc Tini
|
SDRI 220B; Tel: 519-850-2942;
|
|
|
Fax: 519-661-3827
|
EVALUATION: Producing an application that would achieve an acceptable rating (at least 3.0, on a scale of 0-4.9) in a CIHR competition meets the course requirements.
INSTRUCTIONAL INFORMATION: Advice on grant writing is contained in the article by Jacob Kraicer, entitled " The Art of Grantmanship".
|
Ph.D. Comprehensive Examination (requirement for Ph.D program)
|
The comprehensive examination for Ph.D. students in the Department of Physiology and Pharmacology is designed to focus not only on the student's particular area of interest, but also to include studies in related areas deemed to be appropriate by the student's Supervisor(s), Graduate Advisory Committee and Graduate Studies Committee.
The comprehensive examination is administered by an ad hoc Examination Committee, established by the Graduate Studies Committee, consisting of three examiners who are experts in the identified areas. The Chair of the Examination Committee is normally the Graduate Studies Committee Representative on the student's Advisory Committee, but is not an examiner. Members of the Advisory Committee, and extra-departmental faculty, but not the supervisor, may serve on the examination committee.
The student, supervisor and the Advisory Committee prepare a list of topics related to the thesis, suggest examiners, and define an approximate date for the exam. Suggested examiners can include Advisory Committee members provided they are not co-authors on papers by the candidate. The Graduate Studies Committee may modify this list of topics and/or examiners, and is responsible for final approval of this list. The student is informed of the list of topics and the examiners at least four weeks prior to the examination. The examination will normally not be given in the summer months. The grant application, prepared for Physiology 9620 or Pharmacology 9620 defines the general scope of the comprehensive examination.
When a student is registered in a specialty interdisciplinary program, one of the tutor-examiners will normally be a core faculty member from that program.
The examiners' assessment will be based on the ability of the candidate:
- To demonstrate a knowledge of general concepts and principles of the discipline of study, and their application to scientific investigation
- To answer questions of fact in the specified subdisciplines
- To be aware of the historical developments and recent advances in the specified subdisciplines
- To be familiar with current research methods and use factual information to appropriately address novel problems in his/her own and related fields.
- The examination is usually two to three hours in duration and is normally chaired by the Graduate Studies Committee Representative on the student's Advisory Committee.
- Only members of the examination committee are permitted to ask questions; other faculty may attend but do not participate.
- The candidate's supervisor is encouraged to be present for the oral examination but does not participate in questioning or balloting.
- In the unexpected absence of an examiner for the oral component of the comprehensive due to illness or unforeseen circumstances, the exam will proceed with the two remaining examiners. In this case, the Chair of the examination will cast the deciding vote, if necessary.
Number of Attempts
A student may be permitted two attempts at the examination. After two unsuccessful attempts, the student will meet with the Advisory Committee to determine a course of action, which will normally involve withdrawal from the graduate program.
Procedure:
- After introductions, the student will be asked to leave the room, at which time the format of questions (e.g., two rounds of questions, first ~15 min, second ~10 min) and the order of examiners shall be determined.
- The student will be invited back into the room and the examination will begin.
- The chair will ensure that the time constraints are followed.
- At the conclusion of the examination, the candidate will leave the room, and the Chair will invite discussion by the examiners of the student's performance, prior to calling a vote.
- Votes on performance on the examination are collected by written ballots from members of the examination committee. A simple majority decides the outcome of the examination.
- Following the vote, the student's supervisor may comment.
The following outcomes are possible:
1) Pass
2) Failure with the recommendation that the exam be re-taken.
3) Failure. (The student's Advisory Committee shall meet to determine whether student should be required to withdraw from the program.)
- At the conclusion of the examiners' deliberations, the Chair will verbally inform the student of the outcome and transmit any comments the examiners might suggest.
- The Chair of the examining committee will provide the student and advisor with a copy of the examination report from the Chair, stating the results of the examination and, where appropriate, comments on the student's performance and recommendations, if applicable (see form on following page).
- Should it be necessary, the second attempt (and final opportunity) should take place no longer than one month after the first examination.
DEPARTMENT OF PHYSIOLOGY AND PHARMACOLOGY
Ph.D. Comprehensive Examination
Date:
Candidate:
Examining Committee:
Chair:
Examiners:
Comments:
Outcome/Grade:
Recommendations:
Date: _________________________ ___________________________________
Examination Committee Chairman
|
Ph.D. Research Seminar (requirement for Ph.D. program)
|
The Ph.D. research seminar must be completed during the last year of the Ph.D. program. The Ph.D. seminar is normally given as a Departmental seminar within our seminar series. The research seminar is based on thesis work.
Suggested Seminar Content
Scientific Content
- Appropriateness of the literature review
- Hypothesis - and is it based logically on literature?
- Rationale
- Methods, including statistical analysis
- Proposed experiments and expected results
- Results and their interpretation, where appropriate
Presentation Style
- Organization
- Appropriateness of level of explanation
- Use of overheads/slides
Knowledge of area
- Indicated by response to questions
|
Pharmacology 9690 Ph.D. Thesis
|
Students are automatically enrolled when accepted into the Master's program in the Department of Physiology and Pharmacology.
Thesis Information: Guidelines for the preparation and examination of MSc thesis is provided by the Faculty of Graduate Studies.
|
Optional Graduate Courses
Physiology Courses
9452 Fundamental Concepts in Stem Cell Biology
(Grad equivalent of Phys 4520)
|
COURSE INFORMATION: This course explores fundamental concepts in regenerative medicine including stem cell biology and focuses on the physiology and pathophysiology of hematopoiesis and cancer development, blood vessel formation for tissue repair, and cellular transplantation for regenerative therapies. It addresses how basic molecular and cellular processes can be translated into an understanding of relevant human disorders and clinically useful therapies, including pharmacological interventions, through the development of appropriate in vitro and in vivo experimental models to study stem cell functions.
The course entails 13 x 2-hr. lectures.
Course Objectives: By the end of this course, students should be familiar with fundamental concepts in regenerative medicine (including techniques currently employed to study stem cell functions) related to the pathophysiology and therapies of human diseases, including hematopoietic disorders, vascular disease, cancer, and diabetes. Students should also be capable of critical evaluations of related scientific literature
LECTURES: Tuesdays 2:30 p.m. - 4:30 p.m.
ANTIREQUISITE(S): None
PREREQUISITES: Physiology 3120, 3130Y and Physiology 3140A; or Physiology 3120 (with a mark of at least 75%) and Physiology 3140A.
INSTRUCTORS
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Course Manager
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Dr. David Hess
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RRI 4245
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dhess@robarts.ca
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Instructor
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Dr. John DiGuglielmo
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john.diguglielmo@schulich.uwo.ca
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Dr. Cheryle Seguin
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cheryle.seguin@schulich.uwo.ca
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EVALUATION Two in-class quizzes based on previously discussed material, 10% each; Summary and critique of research papers for discussion, 20%; Final exam (3 hours, short-answer and essay questions), 60%
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2009 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9550 Molecular Techniques in Physiology
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Physiology 9550 is an intensive lab course incorporating theoretical knowledge of molecular biology and the techniques used to study molecular questions in ones own research. This course is an introduction to these techniques and is designed to encourage students to incorporate molecular approaches to their own research project. Students will be given standard protocols for all techniques taught, solution recipes, and instruction during the wet lab for trouble shooting all experiments taught. Following completion of this course, students will be able to:
- Determine what experiment should be employed to answer a molecularly based research question, and know the basic steps involved in performing the experiment.
- Design suitable experiments to answer molecular questions, including all appropriate controls
- nterpret and analyze results of a molecular technique, and be able compose an effective figure legend
- Begin performing molecular procedures with some assistance and being able to formulate strategies for trouble shooting experimental procedures
INSTRUCTORS
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Course Manager
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Dr. Anita Woods
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anita.woods@uwo.ca
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Lecturers
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Dr. Anita Woods
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Dr. Frank Beier
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Shirine Usmani
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Ciric To
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EVALUATION: Pre-Lab Preparation 10 %; Module Quizzes (1 per module, 5 total) 15 %; Figure Legends 15%; Lab Participation 10%;Exam 50%
INSTRUCTIONAL INFORMATION: Students will be sent wet lab modules (containing prelab questions) prior to the start of class on August 25th. Students will also be given the recipes for all solutions that are not proprietary. Students will be tested on material taught in lecture and discussed during wet lab procedures. No textbook is required. A recommended textbook available at the UWO bookstore is "Applied Molecular Genetics" by Miesfeld (for students who would like a more comprehensive background on molecular techniques). In addition to the handouts, a variety of other information sources can be consulted. These include general handbooks (e.g. Maniatis [now Sambrook and Russell], or the Promega protocols book) and product-specific handbooks (e.g. the DIG system users' guide from Roche).
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9553 Translational Research
(Bench to Bedside)
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The objective of this course is familiarize students with the approaches and issues associated with taking a basic science discovery through to effective therapeutic use in patient populations. An additional objective is to expand the scope of students' understanding of how their graduate research project fits into the ‘bigger picture' of the advancement of science and medicine.
The course will consist of 3 three week modules focused on the current or historical development of a therapeutic regimen involving:
- a traditional small molecule drug
- a cell based therapy
- a therapy involving a protein or antibody
Each of these development paths has different issues associated with it and incorporates different areas of research. This will be followed by a 4th module in which students make a formal presentation on how their own thesis studies might be extended into the clinical/applied realm. Most of the course will involve small group discussion sessions and student presentations.
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9563 Motor Neurophysiology
(Grad equivalent of Phys 4630)
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COURSE INFORMATION: A study of the neural control of movement in mammals. Topics include normal and abnormal function of muscle receptors, spinal reflexes, cerebellum, basal ganglia and motor areas of cerebral cortex. 2 lecture hours, 0.5 course.
LECTURES: Fridays 2:30 p.m - 4:30 p.m.
ANTIREQUISITE(S): None
PREREQUISITES: Physiology 3120 and Physiology 3130y (or the former Physiology 310); Physiology 3140
INSTRUCTORS:
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Course Manager
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Dr. Stefan Everling
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519-685-8500 x24359
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severlin@uwo.ca
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EVALUATION: Minitests 30%; Midterm 30%; Final Exam 60%
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2009 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9564 Organogenesis in Mammals
(Grad equivalent of Phys 4640)
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COURSE INFORMATION: Mechanisms underlying the development of selected organs and organ systems in mammals: brain and peripheral nervous system, heart and vascular system, pancreas and skeletal muscle. Emphasis is on the biochemical and morphological maturation pathway that equips each system for its physiological role. 2 lecture hours, 0.5 course.
LECTURES: Tuesdays 2:30 p.m. - 4:30 p.m.
ANTIREQUISITE(S): None
PREREQUISITES: Physiology 3120 and Physiology 3130y (or the former Physiology 310); Physiology 3140
INSTRUCTORS
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Course Manager
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Dr. Dean Betts
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MSB 207
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dean.betts@schulich.uwo.ca
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Instructors
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Dr. Tom Drysdale
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tadrysda@uwo.ca
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Dr. Chris Pin
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cpin@uwo.ca
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EVALUATION: Midterm 20%; Quizzes 10%; Oral Presentation 15%; Class Participation 10%; Final Exam 45%
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2009 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9565 Regulatory and Integrative Neurophysiology
(Grad equivalent of Phys4650)
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COURSE INFORMATION: The hypothalamus and limbic system contribute to the neural integration of autonomic, endocrine and skeletomotor responses which contribute to homeostasis and adaptive behaviors. Topics include the regulation of body temperature, blood pressure, energy, water and electrolytes, circadian rhythms and the integration of reproductive function. 2 lecture hours, 0.5 course.
LECTURES: Wednesdays 9:30-11:30 Dental Science Building 2016
PREREQUISITES: Physiology 312 and Physiology 313y (or the former Physiology 310); Physiology 314
INSTRUCTORS
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Course Manager
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Dr. John Ciriello
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DSB 2000 519-661-3484
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Instructors
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Dr. Qingping Feng
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LHSC-SSC 519-685-8300 x75359
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EVALUATION: Participation 5%;Paper presentation/discussion 15%;Minitests 20%; Midterm 20%; Final Exam 40%
FINAL EXAMINATION
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9568 Cellular and Molecular Neurobiology
(Grad equivalent of Phys 4680)
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COURSE INFORMATION: Mechanisms at the cellular and molecular level by which function of neurons and their communication to target cells is regulated. Topics may include mechanisms involved in cell fate determination in the nervous system, specification of neuronal phenotype, neurochemical transmission, receptor signal transduction mechanisms, and receptor-ligand biology. 2 lecture hours, 0.5 course.
LECTURES: Mondays 2:30-4:30 Dental Science Building 2016
PREREQUISITES: Physiology 312 and Physiology 313y (or the former Physiology 310); Physiology 314
INSTRUCTORS
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Course Manager
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Dr. Stan Leung
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Instructors
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Dr. D. Bai
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DSB 00073; 519-850-2569
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Dr. S. Ferguson
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RRI 3-03; 519-663-3825
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EVALUATION: Midterm 40%; Presentation 25%; Final Exam 35%
FINAL EXAMINATION
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9570 Physiology Fetal Physiology
(Grad equivalent of Phys 4700)
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COURSE INFORMATION: Blastocyst implantation, established of the placenta and the development and regulation of fetal cardiovascular, respiratory, CNS, and endocrine functions. The control of fetal growth, metabolism, water balance, and the role of the fetus in parturition are described. The interaction between basic and applied physiology are stressed.
LECTURES: Thursdays 2:30 p.m. - 4:30 p.m.
ANTIREQUISITE(S): None
PREREQUISITES: Physiology 312 and Physiology 313y (or the former Physiology 310); Physiology 314
INSTRUCTORS
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Course Manager
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Dr. Kaiping Yang
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519-685-8500 x55069
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Instructors
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Dr. Robert Gratton
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519-646-6100 x66106
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Dr. Bryan Richardson
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646-6106 x66106
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Dr. Tim Regnault
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519-646-6000 x61446
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EVALUATION
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9571 Physiology of the Senses
(Grad equivalent of Phys 4710)
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COURSE INFORMATION: This course covers the physiology of the senses in the primate, including touch, taste, pain, smell, vision, motion and hearing. Each sensory modality is used to exemplify a particular aspect of sensory processing from stimulus encoding at the periphery to the feature extraction in the sensory cerebral cortex. 2 lecture hours, 0.5 course.
LECTURES: Thursdays 12:30-2:30 Social Science Centre 3018
PREREQUISITES: Physiology 312 and Physiology 313y (or the former Physiology 310); Physiology 314
INSTRUCTORS
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Course Manager
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Dr. Tutis Vilis
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EVALUATION: Midterm 40%; Final Exam 60%
FINAL EXAMINATION
INSTRUCTIONAL INFORMATION: No text book is required for this course.
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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Pharmacology & Toxicology Courses
9536 Mechanisms for Cancer Chemotherapy
(Grad equivalent of Pharm 4360)
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COURSE INFORMATION: This course is designed to give students a basic understanding of the molecular pharmacology and therapeutic properties of anticancer agents. The course will be split into three modules. The lectures in the first module are focused on introducing the principles of chemotherapy as well as drug resistance. The lectures in the second and third modules will focus on novel molecular targets in cancer therapy, namely receptor kinases and G protein-coupled receptors. Where possible, emphasis will be placed on the most recent cell and molecular aspects of cancer. The class will be in lecture and seminar format and meet for 2 hrs each week.
LECTURES: Wednesdays 3:30 p.m. - 5:30 p.m.
ANTIREQUISITE(S): None
PREREQUISITES: Pharmacology and Toxicology 355b, 356a and 358y (the former Pharmacology and Toxicology 357). Open to 4th year undergraduate students in the Dept. of Physiology and Pharmacology. Admission to students from other programs is contingent on departmental approval.
INSTRUCTORS
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Course Manager
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Dr.John Diguglielmo
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519-661-0042
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Instructor
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Dr. James Hammond
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519-661-2111 Ext. 83780
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EVALUATION 3 Quizzes 20%; Oral Presentation 20%; Final Exam 60%
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9543 Pharmacology and Toxicology of Natural Sourced Medicine
(Grad equivalent of Pharm 4430)
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COURSE INFORMATION: Contemporary use of medicines derived from natural sources. Regulatory aspects of their use and the scientific basis for assessment of efficacy, quality, and safety of these products will be discussed. The mechanism(s) of beneficial and harmful effects of selected natural health products, including herb-drug interactions, will be included. 2 lecture hours, 0.5 course.
LECTURES: Thursdays 9:30 a.m. - 11:30 a.m.
ANTIREQUISITE(S): None
PREREQUISITES: Pharmacology and Toxicology 355 and 358y (the former Pharmacology and Toxicology 357), or the former Biology 362, or Pharmacology and Toxicology 355 and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department.
INSTRUCTORS
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Course Manager
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Dr. Edmund Lui
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519-661-3320
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EVALUATION: Midterm 40%; Final Exam 60%
INSTRUCTIONAL INFORMATION: No text book is required for this course.
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9550 Molecular Techniques in Physiology
|
Physiology 9550 is an intensive lab course incorporating theoretical knowledge of molecular biology and the techniques used to study molecular questions in ones own research. This course is an introduction to these techniques and is designed to encourage students to incorporate molecular approaches to their own research project. Students will be given standard protocols for all techniques taught, solution recipes, and instruction during the wet lab for trouble shooting all experiments taught. Following completion of this course, students will be able to:
- Determine what experiment should be employed to answer a molecularly based research question, and know the basic steps involved in performing the experiment.
- Design suitable experiments to answer molecular questions, including all appropriate controls
- nterpret and analyze results of a molecular technique, and be able compose an effective figure legend
- Begin performing molecular procedures with some assistance and being able to formulate strategies for trouble shooting experimental procedures
INSTRUCTORS
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Course Manager
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Dr. Anita Woods
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anita.woods@uwo.ca
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Lecturers
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Dr. Anita Woods
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Dr. Frank Beier
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Shirine Usmani
|
|
|
Ciric To
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|
EVALUATION: Pre-Lab Preparation 10 %; Module Quizzes (1 per module, 5 total) 15 %; Figure Legends 15%; Lab Participation 10%;Exam 50%
INSTRUCTIONAL INFORMATION: Students will be sent wet lab modules (containing prelab questions) prior to the start of class on August 25th. Students will also be given the recipes for all solutions that are not proprietary. Students will be tested on material taught in lecture and discussed during wet lab procedures. No textbook is required. A recommended textbook available at the UWO bookstore is "Applied Molecular Genetics" by Miesfeld (for students who would like a more comprehensive background on molecular techniques). In addition to the handouts, a variety of other information sources can be consulted. These include general handbooks (e.g. Maniatis [now Sambrook and Russell], or the Promega protocols book) and product-specific handbooks (e.g. the DIG system users' guide from Roche).
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
|
9553 Translational Research
(Bench to Bedside)
|
The objective of this course is familiarize students with the approaches and issues associated with taking a basic science discovery through to effective therapeutic use in patient populations. An additional objective is to expand the scope of students' understanding of how their graduate research project fits into the ‘bigger picture' of the advancement of science and medicine.
The course will consist of 3 three week modules focused on the current or historical development of a therapeutic regimen involving:
- a traditional small molecule drug
- a cell based therapy
- a therapy involving a protein or antibody
Each of these development paths has different issues associated with it and incorporates different areas of research. This will be followed by a 4th module in which students make a formal presentation on how their own thesis studies might be extended into the clinical/applied realm. Most of the course will involve small group discussion sessions and student presentations.
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9554 Molecular Pharmacology
(Grad equivalent of Pharm 4540)
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COURSE INFORMATION: The physiology, pathophysiology and pharmacology of cell proliferation and
tissue repair. The course addresses the translation of basic molecular and cellular processes into an understanding of relevant human disorders and clinically useful therapies, through the development of appropriate in vitro and in vivo experimental models.
LECTURES: Wednesdays 9:30 a.m. - 11:30 a.m.
ANTIREQUISITE(S): None
PREREQUISITES: Physiology 3120 or the former Physiology 310; Physiology
3140A or Biology 3316A; Pharmacology and Toxicology 3550A/B and 3580Y, or
the former Pharmacology and Toxicology 357, or Pharmacology and Toxicology
3550A/B and registration in Year 4 of a module in Pathology and Toxicology,
or permission of the Department. Biology 3592A is recommended.
INSTRUCTORS
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Course Manager
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Dr. Lina Dagnino
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ldagnino@uwo.ca
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Instructor
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Dr. John DiGuglielmo
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john.diguglielmo@schulich.uwo.ca
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EVALUATION: Two in-class Quizzes 10%; Summary and critique of research papers for discussion 20%:
Final Exam 60%
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2009 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9555 Drug Development
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COURSE INFORMATION: The Drug Development course consists of 10 sessions, each 90 minutes long.
The purpose of the course is to introduce the student to scientific, regulatory and financial aspects of drug development in Canada and the US. The course will conclude with a discussion of practical concerns related to drug development and approval in an industry setting.
LECTURES: Tuesdays 9:30-11:00 January 8 - March 11, 2008
PREREQUISITES
INSTRUCTORS
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Course Manager
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David Freeman PhD
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Instructors
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Mike Rieder MD.PhD.
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David Bailey PhD.
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David Knoppert BSc.Pharm. MSc.
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Doreen Matsui MD.
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George Dresser MD. PhD.
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Richard Kim MD.
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EVALUATION: Final Exam 100%
FINAL EXAMINATION: There will be one final examination in the Drug Development section. It will represent 100% of the final mark and will take the form of short-answer questions covering material presented by faculty.
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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9557 Pharmacokin Drug Disposition
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COURSE INFORMATION: The purpose of the course is to introduce the student to quantitative analysis of drug disposition and relevance to clinical pharmacology and drug discovery/development. In addition to the mathematical basis for drug disposition, the course also includes material on basic chemical, biochemical, and physiological processes that determine pharmacokinetics. Previous background in pharmacokinetics is unnecessary but basic pharmacology/toxicology knowledge and basic mathematical skills are required. The course consists of 10 didactic sessions and a 2 hr practical session on computer-based pharmacokinetic analysis and simulation. Problem sets will be assigned weekly and students will give 2 presentations on topics related to pharmacokinetics and clinical pharmacology.
INSTRUCTORS
Rommel Tirona, PhD
LECTURES
Mondays 12-2pm. Beginning Jan. 11, 2010 in Room C3-170 (Boardroom) LHSC-University Hospital, then subsequent Mondays in Auditorium D, LHSC-University Hospital.
EVALUATION: Problem sets (30%) and two presentations (35% each).
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9566 Human Toxicology
(Grad equivalent to Pharm 4660)
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COURSE INFORMATION: Human Toxicology is the science dedicated to the interactions between xenobiotics (foreign chemicals) and the human body, leading to acute or chronic adverse events. Adverse responses to drugs and chemicals are a major source of morbidity and mortality in today's society. Mankind, by contaminating his environment, by consuming drugs and by working with potent toxins, - is exposed to major health risks. Yet, despite the major effects of drugs and chemicals on human health, very few universities teach this field in a focused and systematic fashion. A substantial proportion of graduating students in science will head to careers in government health departments and the pharmaceutical and health industries. Many of them are ill prepared to deal with various aspects of human toxicology and drug safety. The new Course in Human Toxicology aims at dosing this gap.
This course entails 11 2-hr. lectures, one meeting a week. The lectures will be based on a large number of medical cases to document toxicological principles and develop a critical approach among students.
LECTURES: Mondays 2:30-4:30p.m. Natural Science 145
ANTIREQUISITE(S): None
PREREQUISITES: Pharmacology and Toxicology 356a/b and 358y, or the former Pharmacology and Toxicology 357; or Pharmacology 356a/b and registration in Year 4 of a module in Pathology and Toxicology, or permission of the Department.
INSTRUCTORS
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Course Manager
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|
Dr. Gideon Koren
|
|
|
EVALUATION: Participation 10%; Midterm 40%; Final Exam 50%
INSTRUCTIONAL INFORMATION
SCHOLASTIC DISCIPLINE: Students are advised to carefully read the section on scholastic discipline in the 2006/07 academic calendar.
UNIVERSITY POLICY FOR PLAGIARISM: Students must write their essays and assignments in their own words. Whenever students take an idea, or a passage from another author, they must acknowledge their debt both by using quotation marks where appropriate and by proper referencing such as footnotes or citations. Plagiarism is a major academic offence (see Scholastic Offence Policy in the Western Academic Calendar).
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