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Disturbed Hemodynamics

Practice your knowledge of the concepts raised in the small group discussions and lectures dealing wth hemodynamics in these clinical scenarios.
In the multiple choice answers click on whichever answer you feel is the best or most appropriate answer. This quiz has been set up to provide you with a series of questions pertaining to a clinical scenario. Each clinical scenario has one to three questions and in most cases images of the normal tissue or organ has been included for comparison to the pathological sample. Complete the questions for each scenario before proceeding on to the next.


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Thrombosis

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delivery: simultaneous question:

Gross specimen of an opened aorta showing a mural thrombus.
Note the bifurcation of the aorta at the iliac arteries and the opening of the superior mesenteric artery just above the thrombus.

This lesion was found in the abdominal aorta of a 50-year-old male who died of a ruptured aneurysm of the aorta. The thrombus is located just before the bifurcation of the aorta into the iliac arteries.
Which of the following statements is correct regarding this lesion? ans: Is not attached to the vessel wall. fbk: Incorrect, a thrombus is attached to the vessel wall, while a blood clot is not. The point of origin of the thrombus is the firmest attachment. ans: Microscopically, there is presence of light and dark bands. fbk: Correct, thrombi contain apparent laminations called 'lines of Zahn' produced by alternating pale layers of platelet and fibrin with darker layers of red cells. ans: Never leaves the site of origin. fbk: Incorrect, a thrombus may dislodge and embolize to other sites in the vasculature. ans: Present along the line of blood flow. fbk: Incorrect, arterial thrombi grow in retrograde direction from the point of origin. ans: Always remain small in size. fbk: Incorrect, thrombi may propagate and grow in size due to accumulation of platelets and fibrin. correct_answer: 2

question: This lesion can most likely occlude which of the following blood vessels? ans: Pulmonary artery. fbk: Incorrect, pulmonary artery occlusion occurs most commonly as a complication of deep vein thrombosis of the leg. ans: Pulmonary vein. fbk: Incorrect, is not a common site for occlusion. ans: Splenic artery. fbk: Incorrect, the thrombus is located below the opening of the superior mesenteric artery and thus is not likely to occlude the splenic artery. ans: Popliteal artery. fbk: Correct, this is a possible outcome anatomically. A thrombus in this location is most likely to dislodge and embolize through the iliacs to the peripheral arteries. ans: Carotid artery. fbk: Incorrect, mostly occurs due to thrombi in the ascending part or the arch of aorta. correct_answer: 4