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Welcome to the Kerfoot Lab

Dr. Steven Kerfoot
Assistant Professor

Dept. of Microbiology & Immunology
University of Western Ontario
London, Ont.
N6A 5C1
CANADA
Office Phone: 519-850-2329
Lab Phone: 661-2111 x82972
Fax: 519-661-3499
Email: Steven Kerfoot <skerfoot@uwo.ca>


T cells and B cells are tasked with targeting and regulating immune responses. When this goes wrong, autoimmune disease can result. Multiple Sclerosis is an autoimmune disease that targets the central nervous system. We study the mechanisms by which B and T cells drive chronic inflammation of the brain and spinal cord. These cells move and interact with each other within lymphoid tissue, where immune responses originate, as well as within the inflamed tissue. We visualize these interactions to understand their consequences and how they contribute to disease.


Recent Publications:

Kerfoot S.M., Yaari G., Patel J.R., Johnson K.L., Gonzalez D.G., Kleinstein S.H., and Haberman A.M. Germinal Center B cell and T Follicular Helper cell development initiates in the interfollicular zone. Immunity, 2011; 34(6): 947-960.

Cellular choreography in the germinal center: new visions from in vivo imaging. Hauser AE, Kerfoot SM, Haberman AM. Semin Immunopathol. 2010 Sep;32(3):239-55. Epub 2010 Jul 9.

 

 


 

 

 

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