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This is a select list of our publications, access the Researcher's home page for a complete listing of their publications


Functional analysis of the C-terminal region of human adenovirus E1A reveals a misidentified nuclear localization signal
Michael J. Cohen, Cason R. King, Jimmy D. Dikeakos, Joe S. Mymryk
Virology, 468–470, November 2014, Pages 238–243

Lentivector integration sites in ependymal cells from a model of metachromatic leukodystrophy: non-B DNA as a new factor influencing integration. McAllister RG, Liu J, Woods MW, Tom SK, Rupar CA, Barr SD. Molecular Therapy Nucleic Acids. 2014 Aug 26;3:e187

The Multifunctional Sorting Protein PACS-2 Regulates SIRT1-Mediated Deacetylation of p53 to Modulate p21-Dependent Cell-Cycle Arrest. Katelyn M. Atkins, Laura L. Thomas, Jonathan Barroso-González, Laurel Thomas, Sylvain Auclair, Jun Yin, Hyeog Kang, Jay H. Chung, Jimmy D. Dikeakos, Gary Thomas.

Rytelewski M, Buensuceso A, Leong HS, Deroo BJ, Chambers AF, Koropatnick J. Evaluating the effectiveness of cancer drug sensitization in vitro and in vivo. JoVE (In press August 2014)

Identification of a positively-charged platform in Staphylococcus aureus HtsA that is essential for ferric staphyloferrin A transport. Cooper JD, Hannauer M, Marolda CL, Briere LA, Heinrichs DE., Biochemistry. 2014 Jul 22. [Epub ahead of print]

Lau A; Khan K; Pavlosky A; Yin Z; Huang X; Haig A; Liu W; Singh B; Zhang ZX; Jevnikar AM. Serine Protease Inhibitor-6 Inhibits Granzyme B-Mediated Injury of Renal Tubular Cells and Promotes Renal Allograft Survival. Transplantation; 2014 Jun (in press); PubMed ID: 24918613

Bellemore SM; Nikoopour E; Au BC; Krougly O; Lee-Chan E; Haeryfar SM; Singh B. Anti-atherogenic peptide Ep1.B derived from Apolipoprotein E induces tolerogenic plasmacytoid dendritic cells. Clin Exp Immunol; 2014 May (in press); PubMed ID: 24784480

Nikoopour E, Singh B. Reciprocity in microbiome and immune system interactions and its implications in disease and health. Inflamm Allergy Drug Targets; 2014 Apr 13; 13(2):94-104. PubMed ID: 24678760

Anantha, R.V., D. Mazzuca, S. X. Xu. B. Shrum, T. Mele, D. Fraser, C. Martin, S.M. Haeryfar, J. K. McCormick. Th2-polarized invariant natural killer T cells reduce disease severity in intra-abdominal sepsis. Clinical and Experimental Immunology. In press.

S Meshkibaf, MW Gower, GA Dekaban and SO Kim: G-CSF preferentially supports the generation of gut-homing Gr-1high macrophages in M-CSF-treated bone marrow cells. Journal of Leukocyte Biology (accepted)

Xu, S. X., K. J. Gilmore, P. A. Szabo, J. J. Zeppa, M. L. Baroja, S. M. M. Haeryfar, and J. K. McCormickSuperantigens subvert the neutrophil response to promote abscess formation and enhance Staphylococcus aureus survival in vivo. Infection and Immunity. In press.

Ancient and Recent Adaptive Evolution in the Antiviral TRIM22 Gene: Identification of a Single Nucleotide Polymorphism that Impacts TRIM22 Function. 2014. Jenna N. Kelly, Matthew W. Woods, Sintia Xhiku and Stephen D. Barr. Human Mutation. Accepted manuscript online: 26 MAY 2014 10:39PM EST | DOI: 10.1002/humu.22595

Reid, G. 2014. Modulating the vaginal microbiome: the need for a bridge between science and practice. Semin Reprod Med. 32(1):28-34

Yang, S, W. Li, J. R.G. Challis, G. Reid, S. O. Kim, and A. D. Bocking. 2014. Probiotic Lactobacillus rhamnosus GR-1 supernatant prevents lipopolysaccharide-induced preterm birth and reduces inflammation in pregnant CD-1 mice. Am. J. Obstetr. Gynecol. 211(1):44.e1-44.e12.

Goneau, L. W., N. S. Yeoh, K. W. MacDonald, P. Cadieux, J. P. Burton, and G. Reid. 2014. Selective antibiotic target inactivation results in persister cell formation and is associated with recurrent urinary tract infection.Antimicrob. Agents Chemother. 58(4):2089-97.

Li, W., S. Yang, S. O. Kim, G. Reid, J. R. Challis, and A. D. Bocking. 2014. Lipopolysaccharide-induced profiles of cytokine, chemokine, and growth factors produced by human decidual cells are altered by Lactobacillus rhamnosus GR-1 supernatant. Reprod Sci. 21(7):939-947.

Reid, G., N. Nduti, W. Sybesma, R. Kort, T. R. Kollmann, R. Adam, H. Boga, E. M. Brown, A. Einerhand, H. El-Nezami, G. B. Gloor, I. I. Kavere, J. Lindahl, A. Manges, W. Mamo, R. Martin, A. McMillan, J. Obiero, P. A. Ochieng', A. Onyango, S. Rulisa, E. Salminen, S. Salminen, A. Sije, J. R. Swann, W. Van Treuren, D. Waweru, and S. Kemp. 2014. Harnessing microbiome and probiotic research in sub-Saharan Africa: recommendations from an African workshop. Microbiome 2:12. DOI: 10.1186/2049-2618-2-12

Sheridan, P. O., L. Bindels, D. M. Saulnier, G. Reid, E. Nova, K. Holmgren, P. W. O’Toole, N. Delzenne, and K. P. Scott. 2014. Can prebiotics and probiotics improve therapeutic outcomes of undernourished individuals? Gut Microbes 5(1):74-82.

Chaban, B., M. G. Links, T. P. Jayaprakash, E. Wagner, D. Bourque, Z. Lohn, A. Y.K. Albert, J. van Schalkwyk, G. Reid, S. Hemmingsen, J. E. Hill, and D. Money. 2014. Characterization of the vaginal microbiome of healthy Canadian women through the menstrual cycle. Microbiome in press.

Hill, C., F. Guarner, G. Reid, G. Gibson, D. Merenstein, B. Pot, L. Morelli, R. Canani, H. Flint, S. Salminen, P. Calder, and M. E. Sanders. 2014. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotics. Nat. Reviews Gastroenterol. Hepatol. June 10 online

Urbaniak, C., A. McMillan, M. Angelini, G. B. Gloor, M. Sumarah, J. P. Burton and G. Reid, 2014. Case study: Effect of chemotherapy on the microbiome and metabolome of human milk. Microbiome 2: 24.

Gan X., T., G. Ettinger, C. X. Huang, J. P. Burton, J. V. Haist, V. Rajapurohitam, J. E. Sidaway, G. Martin, G. B. Gloor, J. R. Swann, G. Reid, and Karmazyn, M. 2013. Probiotic administration attenuates myocardial hypertrophy and heart failure following myocardial infarction in the rat. Circul. Heart Failure 7(3):491-9.

Bisanz, J. E., S. Seney, A. McMillan, R. Vongsa, D. Koenig, L-F.Wong, B. Dvoracek, G.B. Gloor, M. Sumarah, B. Ford, D. Herman, J. P. Burton, and G. Reid. 2014. A systems biology approach investigating the effect of Lactobacillus rhamnosus GR-1 and L. reuteri RC-14 on the vaginal microbiome and host responses in a double blind, placebo-controlled clinical trial of post-menopausal women with intermediate Nugent scores. PLoS ONE in press.

Bisanz, J. E., J. M. Macklaim, G. B. Gloor, and G. Reid. 2014. Bacterial metatranscriptome analysis of a probiotic yogurt using an RNA-Seq approach. Int Dairy J. in press.

Jenna Kelly and Stephen Barr. In Silico Analysis of Functional Single Nucleotide Polymorphisms in the Human TRIM22 Gene. PLoS One 2014 Jul 1; 9(7):e101436

Kasper, K. J., J. J. Zeppa, A. T. Wakabayashi, S. X. Xu, D. M. Mazzuca, I. Welch, M. L. Baroja, M. Kotb, E. Cairns, P. P. Cleary, S. M. M. Haeryfar and J. K. McCormick. Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC class II-dependent manner. PLoS Pathogens.

S-D Ha, CY Han, C Reid, SO Kim. "HDAC8-mediated epigenetic reprogramming plays a key role in resistance to anthrax lethal toxin-induced pyroptosis in macrophages". Journal of Immunology, In press.

Rytelewski M, Tong J, Buensuceso A, Leong HS, Maleki Vareki S, Figueredo R, Di Cresce C, Wu SY, Herbrich S, Baggery KA, Romanow L, Shepherd T, Deroo BJ, Sood AK, Chambers AF, Vincent M, Ferguson PJ, Koropatnick J. BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis. Molecular Oncology. In press [May 2014]

Maleki Vareki S, Rytelewski M, Figueredo R, Chen D, Ferguson PJ, Vincent M, Min W, Zheng X, Koropatnick J. Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation, and cisplatin. Oncotarget. 2014 Apr 18. [Epub ahead of print]

Control of Established Colon Cancer Xenografts Using a Novel Humanized Single Chain Antibody-Streptococcal Superantigen Fusion Protein Targeting the 5T4 Oncofetal Antigen. Patterson KG, Dixon Pittaro JL, Bastedo PS, Hess DA, Haeryfar SM, McCormick JK.
PLoS One. 2014 Apr 15;9(4):e95200. doi: 10.1371/journal.pone.0095200. eCollection 2014. PMID: 24736661

A robust scoring system to evaluate sepsis severity in an animal model.
Shrum B, Anantha RV, Xu SX, Donnelly M, Haeryfar SM, McCormick JK, Mele T.
BMC Res Notes. 2014 Apr 12;7(1):233

Identification and characterization of multiple conserved nuclear localization signals within adenovirus E1A. Marshall KS, Cohen MJ, Fonseca GJ, Todorovic B, King CR, Yousef AF, Zhang Z, Mymryk JS. Virology. 2014 Apr;454-455C:206-214. doi: 10.1016/j.virol.2014.02.020. Epub 2014 Mar 13.

Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export. Woods MW, Tong JG, Tom SK, Szabo PA, Cavanagh CP, Dikeakos JD, Haeryfar SMM, Barr SD. Retrovirology.2014, 11:27.  DOI: 10.1186/1742-4690-11-27.

TCA cycle activity in Staphylococcus aureus is essential for iron-regulated synthesis of staphyloferrin A, but not staphyloferrin B: the benefit of a second citrate synthase. Sheldon JR, Marolda CL, Heinrichs DE. Mol Microbiol. 2014 Mar 26. doi: 10.1111/mmi.12593. [Epub ahead of print]

Bacterial microbiota of human breast tissue. Camilla Urbaniak, Joanne Cummins, Muriel Brackstone, Jean M. Macklaim, Gregory B. Gloor, Chwanrow K. Baban, Leslie Scott, Deidre M. O’Hanlon, Jeremy P.Burton, Kevin P. Francis, Mark Tangney, Gregor Reid. AEM Accepts, published online ahead of print on 7 March 2014 Appl. Environ. Microbiol. doi:10.1128/AEM.00242-14

Singh B. 2014. Prevention of type 1 diabetes and its recurrence by immunotherapy with Mycobacterial adjuvants in "The Value of BCG and TNF in Autoimmunity", Ed. Faustman DL Publisher: Elsevier Chapter 2, pp27-36.

PU.1 promotes cell cycle exit in the murine myeloid lineage associated with downregulation of E2F1. Rachel Ziliotto, Marek R. Gruca, Shreya Podder, Greg Noel, Cora K. Ogle, David A. Hess, and Rodney P. DeKoter. Experimental Hematology 2014;42:204–217

The human papillomavirus E7 proteins associate with and alter p190RhoGAP function. Biljana Todorovic,
 Anthony C. Nichols, Jennifer M. Chitilian, Michael P. Myers, Trevor G. Shepherd, Sarah J. Parsons, John W. Barrett, Lawrence Banks, Joe S. Mymryk. Published ahead of print 8 January 2014, doi: 10.1128/JVI.03263-13

Negative regulation of the peptidylarginine deiminase type IV promoter by NF-κB in human myeloid cells. Abbas AK, Le K, Pimmett VL, Bell DA, Cairns E, Dekoter RP. Gene. 2014 Jan 1;533(1):123-31. doi: 10.1016/j.gene.2013.09.108. Epub 2013 Oct 16.

Antihomocitrullinated Fibrinogen Antibodies are Specific to Rheumatoid Arthritis and Frequently Bind Citrullinated Proteins/peptides. Scinocca M, Bell DA, Racapé M, Joseph R, Shaw G, McCormick JK, Gladman DD, Pope J, Barra L, Cairns E. J Rheumatol. 2014 Jan 15. [Epub ahead of print]

Serum Cytokine Profile of Unaffected First-degree Relatives of Patients with Rheumatoid Arthritis. Barra L, Summers K, Bell D, Cairns E. J Rheumatol. 2014 Jan 15. [Epub ahead of print]

Villanueva AI, Haeryfar SM, Mallard BA, Kulkarni RR, Sharif S: Functions of invariant natural killer T cells are modulated by Toll-like receptor ligands and interferon-alpha. Innate Immunity 2014

Vasostatin-1 antigenic epitope mapping for induction of cellular and humoral immune responses to chromogranin A autoantigen in NOD mice  Enayat Nikoopour, Rebecca Cheung, Stacey Bellemore, Olga Krougly, Edwin Lee-Chan, Mats Stridsberg, Bhagirath Singh. Eur. J. Immunol.  2014; 44: (in press). Accepted manuscript online: 14 Jan. 2014; DOI: 10.1002/eji.201343986

Probiotics, prebiotics, and the host microbiome: the science of translation. Bryon Petschow1 Joel Dor´ e, Patricia Hibberd Timothy Dinan, Gregor Reid, Martin Blaser, Patrice D. Cani, Fred H. Degnan, Jane Foster, Glenn Gibson, John Hutton, Todd R. Klaenhammer, Ruth Ley, Max Nieuwdorp, Bruno Pot, David Relman, Andrew Serazin, and Mary Ellen Sanders. Ann. N.Y. Acad. Sci. ISSN 0077-8923

Crystal and Solution Structure Analysis of FhuD2 from Staphylococcus aureus in Multiple Unliganded Conformations and Bound to Ferrioxamine-B. Podkowa KJ, Briere LA, Heinrichs DE, Shilton BH. Biochemistry. 2014 Mar 8. [Epub ahead of print]

Adenovirus E1A recruits the hPaf1 complex to enhance transcriptional elongation. Gregory J. Fonseca, Michael J. Cohen and Joe S. Mymryk. Published ahead of print 5 March 2014, doi: 10.1128/JVI.03518-13 JVI.03518-13

Growth promotion of the opportunistic human pathogen, Staphylococcus lugdunensis, by heme, hemoglobin, and coculture with Staphylococcus aureus. Brozyna JR, Sheldon JR, Heinrichs DE. MicrobiologyOpen. 2014 Feb 7. doi: 10.1002/mbo3.162. [Epub ahead of print]

Rytelewski M, Meilleur CE, Atef Yekta M, Szabo PA, Garg N, Schell TD, Jevnikar AM, Sharif S, Singh B, Haeryfar SM: Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase. PLoS ONE 2014 (accepted)

Antihomocitrullinated Fibrinogen Antibodies are Specific to Rheumatoid Arthritis and Frequently Bind Citrullinated Proteins/peptides. Scinocca M, Bell DA, Racapé M, Joseph R, Shaw G, McCormick JK, Gladman DD, Pope J, Barra L, Cairns E. J Rheumatol. 2014 Jan 15. [Epub ahead of print]



Anti-citrullinated protein antibodies in unaffected first-degree relatives of rheumatoid arthritis patients. Barra L, Scinocca M, Saunders S, Bhayana R, Rohekar S, Racapé M, Coles R, Cairns E, Bell DA. Arthritis Rheum. 2013 Jun;65(6):1439-47. doi: 10.1002/art.37911.

Bhagirath Singh, Jordan Ari Schwartz, Christian Sandrock, Stacey M. Bellemore & Enayat Nikoopour 2013. Modulation of Autoimmune Diseases by IL-17 producing Regulatory Th17 cells. Indian J Med Res. 138: 591-594.

Pischany, G, J.R. Sheldon, C.F. Dickson, T. Alam, T.D. Read, D.A. Gell, D.E. Heinrichs and E.P. Skaar. 2014. IsdB-dependent hemoglobin binding is required for acquisition of heme by Staphylococcus aureus. Journal of Infectious Diseases. In press

Kobylarz, M.J., J.C. Grigg, D.K. Rai, D.E. Heinrichs and M.E.P. Murphy. 2014. Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor. Chemistry & Biology. In press.

Vines, E.D., C.D. Speziali and D.E. Heinrichs. 2014. Demonstration of the functional role of conserved Glu-Arg residues in the Staphylococcus aureus ferrichrome transporter. BioMetals. In press.

Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides. Lee MJ, Gravelat FN, Cerone RP, Baptista SD, Campoli PV, Choe SI, Kravtsov I, Vinogradov E, Creuzenet C, Liu H, Berghuis AM, Latgé JP, Filler SG, Fontaine T, Sheppard DC. J. Biol. Chem. published online November 20, 2013

Staphylococcus δ-toxin induces allergic skin disease by activating mast cells. Yuumi Nakamura, Jon Oscherwitz, Kemp B. Cease, Susana M. Chan, Raul Muñoz-Planillo,    Mizuho Hasegawa, Amer E. Villaruz, Gordon Y. C. Cheung, Martin J. McGavin, Jeffrey B. Travers, Michael Otto, Naohiro Inohara & Gabriel Núñez. Nature (2013) doi:10.1038/nature12655 Received  12 November 2012  Accepted  12 September 2013  Published online  30 October 2013

Negative regulation of the peptidylarginine deiminase type IV promoter by NF-kappa B in human myeloid cells. Ali K. Abbas, Kevin Le, Virginia L. Pimmett, David A. Bell, Ewa Cairns, and Rodney P. DeKoter. Gene (2013) in press.

The adenovirus 55 residue E1A protein is a transcriptional activator and binds the unliganded thyroid hormone receptor. Vishnuka D Arulsundaram,  Paul Webb,  Ahmed F Yousef,  Peter Pelka,  Gregory J Fonseca,  John D Baxter,  Paul G Walfish and  Joe S Mymryk. Published October 17, 2013 as doi:10.1099/vir.0.056838-0

Pasternak Z, Njagi M, Shani Y, Chanyi R, Rotem O, Lurie-Weinberger MN, Koval S, Pietrokovski S, Gophna U, Jurkevitch E. In and out: an analysis of epibiotic vs. periplasmic bacterial predators. The ISME Journal, October 3, 2013; doi:10.1038/ismej.2013.164

Anantha, R.V., K. J. Kasper, K. G. Patterson, J. J. Zeppa, J. Delport, J. K. McCormick. Fournier’s gangrene of the penis caused by Streptococcus dysgalactiae subspecies equisimilis: Case report and incidence study in a tertiary-care hospital. BMC Infectious Diseases. 13:381.

Characterization of the AtsR phosphorelay pathway and identification of its response regulator in Burkholderia cenocepacia. Maryam Khodai-Kalaki, Daniel F. Aubert and Miguel A. Valvano. September 6, 2013, doi: 10.1074/jbc.M113.489914

Dissection of the C-terminal region of E1A re-defines the roles of CtBP and other cellular targets in oncogenic transformation. Cohen MJ, Yousef AF, Massimi P, Fonseca GJ, Todorovic B, Pelka P, Turnell AS, Banks L, Mymryk JS. Published ahead of print 17 July 2013, doi: 10.1128/JVI.00786-13

Comparison of predicted epimerases and reductases of the Campylobacter jejuni D-altro- and L-gluco- heptose synthesis pathways. Matthew McCallum, Gary S. Shaw and Carole Creuzenet. JBC Papers in Press. Published on May 20, 2013

Chemical communication of antibiotic resistance by a highly resistant subpopulation of bacterial cells. El-Halfawy OM, Valvano MA. PLoS One. 2013 Jul 3;8(7):e68874. doi: 10.1371/journal.pone.0068874. Print 2013

Rosales-Reyes R, Aubert DF, Tolman JS, Amer AO, Valvano MA (2012) Burkholderia cenocepacia Type VI Secretion System Mediates Escape of Type II Secreted Proteins into the Cytoplasm of Infected Macrophages. PLoS ONE 7(7): e41726. doi:10.1371/journal.pone.0041726

Fonseca GJ, Cohen MJ, Nichols AC, Barrett JW, Mymryk JS (2013) Viral Retasking of hBre1/RNF20 to Recruit hPaf1 for Transcriptional Activation. PLoS Pathog 9(6): e1003411. doi:10.1371/journal.ppat.1003411

Heit et al., Multimolecular Signaling Complexes Enable Syk-Mediated Signaling of CD36 Internalization, Developmental
Cell (2013), http://dx.doi.org/10.1016/j.devcel.2013.01.007

Genetically modified VSVNJ vector is capable of accommodating a large foreign gene insert and allows high level gene expression. C.Y., Kang et. al. Virus Research, Volume 171, Issue 1, January 2013, Pages 168–177

"p62/SQSTM1 enhances NOD2-mediated signaling and cytokine production through stabilizing NOD2 oligomerization" Sangwook Park, Soon-Duck Ha, Macon Coleman, Shahab Meshkibaf, Sung Ouk Kim. PLoS One 2013 Feb. in press.

Mateusz Rytelewski, Peter J. Ferguson, Saman Maleki Vareki, Rene Figueredo, Mark Vincent, James Koropatnick. "Inhibition of BRCA2 and thymidylate synthase creates multi-drug sensitive tumor cells via induction of combined 'complementary lethality'." Molecular Therapy - Nucleic Acids (In press February 2013)

"To invade or not to invade:  two approaches to a prokaryotic predatory life cycle." Ryan Chanyi, Caitlin Ward, Andrea Pechey and Susan Koval.  Canadian Canadian Journal of Microbiology, 10.1139/cjm-2013-0041.

MacPhee, R., W. L. Miller, G. B. Gloor, J. K. McCormick, J. P. Burton, G. Reid. 2013. Influence of vaginal microbiota on toxic shock syndrome toxin-1 production by Staphylococcus aureus. Applied and Environmental Microbiology. 79(6):1835-42.

The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia. Sass AM, Schmerk C, Agnoli K, Norville PJ, Eberl L, Valvano MA, Mahenthiralingam E. ISME J. 2013 Mar 14. doi: 10.1038/ismej.2013.36.

Hill T, Krougly O, Nikoopour E, Bellemore S, Lee-Chan E, Fouser LA, Hill DJ and Singh B. The involvement of Interleukin-22 in the expression of Pancreatic Beta cell Regenerating Reg genes. Cell Regeneration. 2013; 2:2 (in press);  doi:10.1186/2045-9769-2-2

Nazemi A, Haeryfar SM, Gillies ER: Multifunctional Dendritic Sialopolymersomes as Potential Antiviral Agents: Their Lectin Binding and Drug Release Properties. Langmuir 2013 (in press)



Hattlmann, C.J., Kelly, J.N. and Barr, S.D. TRIM22: A diverse and dynamic antiviral protein. Molecular Biology International. Volume 2012 (2012), Article ID 153415.

Effect of environmental stress factors on the uptake and survival of Campylobacter jejuni in Acanthamoeba castellanii. Xuan Thanh Bui, Klaus Qvortrup, Anders Wolff, Dang Duong Bang and Carole Creuzenet. BMC Microbiology 2012, 12:232 

Complete 6-deoxy-D-altro-heptose biosynthesis pathway from Campylobacter jejuni: more complex than anticipated. McCallum M, Shaw SD, Shaw GS, Creuzenet C. J Biol Chem. 2012 Jul 11. [Epub ahead of print]

Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia. Xu, L. S., Sokalski, K. M., Hotke, K., Christie, D. A., Zarnett, O., Piskorz, J., Thillainadesan, G., Torchia, J., and DeKoter, R. P. 2012. Journal of Immunology, in press.

Noel G., DeKoter R., Wang Q., Hexley P., Ogle CK. Optimization and application of a flow cytometric PU.1 assay for murine immune cells. Journal of Immunological Methods 2012 May 11 [Epub ahead of print].

Peyer’s patch M cells derived from Lgr5+ stem cells require Spi-B and are induced by RankL in cultured ‘miniguts’. De Lau, W., Kujala, P., Schneeberger, K., Middendorp, S., Li, V. S. W., Barker, N., Martens, A., Hofhuis, F., DeKoter, R. P., Peter, P. J., Nieuwenhuis, E., Clevers, H. Molecular and Cellular Biology 18:3639-47, 2012.

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I. Dikeakos JD, Thomas L, Kwon G, Elferich J, Shinde U, Thomas G. Mol Biol Cell. 2012 Jun;23(11):2184-97. Epub 2012 Apr 11. PMID: 22496420 [PubMed - in process]

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I. Dikeakos JD, Thomas L, Kwon G, Elferich J, Shinde U, Thomas G. Mol Biol Cell. 2012 Jun;23(11):2184-97. Epub 2012 Apr 11. PMID: 22496420 [PubMed - in process]

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2). Werneburg NW, Bronk SF, Guicciardi ME, Thomas L, Dikeakos JD, Thomas G, Gores GJ. J Biol Chem. 2012 May 29. [Epub ahead of print] PMID: 22645134 [PubMed - as supplied by publisher]

Kulkarni R, Villanueva AI, Elawadli I, Jayanth P, Read LR, Haeryfar SM, Sharif S: Costimulatory activation of murine invariant natural killer T cells by Toll-like receptor agonists. Cellular Immunology 2012 (in press)

Cheung, J., M.E.P. Murphy and D.E. Heinrichs.  2012. Discovery of an iron-regulated citrate synthase in Staphylococcus aureus. Chemistry & Biology. 19: 1568-1578.

Robust induction of the staphylococcal proteolytic cascade by unsaturated antimicrobial fatty acids in the USA300 strain of community acquired methicillin resistant Staphylococcus aureus.  Arsic, B., Y. Zhu, D.E. Heinrichs and M.J. McGavin. 2012. PLOS One.  Epub Sept 24.

The multi-protein heme shuttle pathway in Staphylococcus aureus: Isd cog-wheel kinetics. Tiedemann, M.T., D.E. Heinrichs and M.J. Stillman. 2012. J. Am. Chem. Soc.  Epub Sept 17.

Sheldon JR and Heinrichs DE (2012) The iron-regulated staphylococcal lipoproteins. Front. Cell. Inf. Microbio. 2:41. Published online: 04 April 2012.

Genetically modified VSVNJ vector is capable of accommodating a large foreign gene insert and allows high level gene expression. C.Y., Kang et. al. Virus Research accepted for publication

Cellular Adaptation to Anthrax Lethal Toxin-Induced Mitochondrial Cholesterol Enrichment, Hyperpolarization, and ROS Generation through Down-regulating MLN64 in Macrophages. Ha SD, Park S, Han CY, Nguyen ML, Kim SO. Mol Cell Biol. 2012 Oct 1. [Epub ahead of print] PMID: 23028046

Reduction of tumorigenicity by placental extracts. Marleau AM, McDonald G, Koropatnick J, Chen CS, Koos D. Anticancer Res. 2012 Apr;32(4):1153-61.

Susan F. Koval, Sandra H. Hynes, Ronald S. Flannagan, Zohar Pasternak, Yaacov Davidov, and Edouard Jurkevitch Bdellovibrio exovorus sp. nov., a novel predator of Caulobacter crescentus Int J Syst Evol Microbiol ijs.0.039701-0; published ahead of print February 24, 2012, doi:10.1099/ijs.0.039701-0

Xu SX and McCormick J (2012). Staphylococcal superantigens in colonization and disease. Front. Cell. Inf. Microbio. 2:52. doi: 10.3389/fcimb.2012.00052

McGavin MJ, Arsic B and Nickerson NN (2012). Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30. Front. Cell. Inf. Microbio. 2:48. doi: 10.3389/fcimb.2012.00048

The staphylococci and staphylococcal pathogenesis. McGavin, M.J. and D.E. Heinrichs. 2012. Front. Cell. Infect. Microbiol. 2: 66

Conserved region 3 of human papillomavirus 16 E7 contributes to deregulation of the retinoblastoma tumor suppressor. Biljana Todorovic, Katherine Hung, Paola Massimi, Nikita Avvakumov, Frederick A. Dick, Gary S. Shaw, Lawrence Banks and Joe S. Mymryk. Published ahead of print 26 September 2012, doi: 10.1128/JVI.01637-12

Frequent Mutations in TP53 and CDKN2A Found by Next-Generation Sequencing of Head and Neck Cancer Cell Lines. Nichols AC, Yoo J, Palma DA, Fung K, Franklin JH, Koropatnick J, Mymryk JS, Batada NN, Barrett JW. Arch Otolaryngol Head Neck Surg. 2012 Aug 1;138(8):732-9.

Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. Jai Ablack, Michael Cohen, Gobi Thillainadesan, Gregory J. Fonseca, Peter Pelka, Joe Torchia, and Joe S. Mymryk. J. Virology, May 2012

G.J. Fonseca, G. Thillainadesan, A.F. Yousef, J.N. Ablack, K.L. Mossman, J. Torchia, J.S. Mymryk. Adenovirus Evasion of Interferon-Mediated Innate Immunity by Direct Antagonism of a Cellular Histone Posttranslational Modification.  Cell Host & Microbe, Volume 11, Issue 6, 597-606, 14 June 2012

TGF-β-Dependent Active Demethylation and Expression of the p15(ink4b) Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex. Thillainadesan G, Chitilian JM, Isovic M, Ablack JN, Mymryk JS, Tini M, Torchia J. Mol Cell. 2012 May 2. [Epub ahead of print]

Ki-67 expression predicts radiotherapy failure in early glottic cancer. Nichols AC, Whelan F, Basmaji J, Dhaliwal S, Dowthwaite S, Chapeskie C, Read N, Palma DA, Fung K, Venkatesan V, Alex Hammond J, Franklin JH, Siddiqui I, Wehrli B, Kwan K, Koropatnick J, Mymryk JS, Barrett JW, Yoo J. J Otolaryngol Head Neck Surg. 2012 Apr 1;41(2):124-30.

Yousef AF,FonsecaGJ, Cohen MJ,MymrykJS. The C-terminal region of E1A: A molecular too for cellular cartography. Biochem Cell Biol. 2012 Jan 31. [Epub ahead of print]

Adhesion of Lactobacillus iners AB-1 to Human Fibronectin: A Key Mediator for Persistence in the Vagina? McMillan A, Macklaim JM, Burton JP, Reid G. Reprod Sci. 2012 Nov 30. [Epub ahead of print]

Micronutrient supplemented probiotic yogurt for HIV-infected adults taking HAART in London, Canada. Hemsworth JC, Hekmat S, Reid G. Gut Microbes. 2012 Sep-Oct;3(5):414-9.

HPV Type Distribution and Cervical Cytology among HIV-Positive Tanzanian and South African Women. Dols JA, Reid G, Brown JM, Tempelman H, Bontekoe TR, Quint WG, Boon ME. ISRN Obstet Gynecol. 2012;2012:514146. 

Probiotic interference of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 with the opportunistic fungal pathogen Candida albicans. Köhler GA, Assefa S, Reid G. Infect Dis Obstet Gynecol. 2012;2012:636474. 

A Canadian Working Group report on fecal microbial therapy: microbial ecosystems therapeutics. Allen-Vercoe E, Reid G, Viner N, Gloor GB, Hota S, Kim P, Lee C, O'Doherty K, Vanner SJ, Weese JS, Petrof EO. Can J Gastroenterol. 2012 Jul;26(7):457-62. 

Bioremediation and tolerance of humans to heavy metals through microbial processes: a potential role for probiotics? Monachese M, Burton JP, Reid G. Appl Environ Microbiol. 2012 Sep;78(18):6397-404. 

Breast, milk and microbes: a complex relationship that does not end with lactation. Urbaniak C, Burton JP, Reid G. Womens Health (Lond Engl). 2012 Jul;8(4):385-98.

Macklaim JM, Cohen CR, Donders G, Gloor GB, Hill JE, Parham GP, Ravel J, Spear G, van de Wijgert J, Reid G. Exploring a Road Map to Counter Misconceptions About the Cervicovaginal Microbiome and Disease. Reprod Sci. 2012 May 21.

Adhesion Forces and Coaggregation between Vaginal Staphylococci and Lactobacilli. Jessica A. Younes, Henny C. van der Mei, Edwin van den Heuvel, Henk J. Busscher, Gregor Reid. PLoS ONE.

Whaling, M., I. Luginaah, G. Reid, S. Hekmat, A. Thind, J. Mwanga, and J. Changalucha. 2011. Perceptions of probiotic yogurt for health and nutrition in the context of HIV/AIDS in Mwanza, Tanzania. J. Health Popul. Nutr. In press

Kiaii B, Fox S, Swinamer SA, Rayman R, Higgins J, Cleland A, Fernandes P, Macdonald J, Dobkowski WB, Stitt LW, Novick RJ, Singh B, Bureau Y, Summers K. The early inflammatory response in a mini-cardiopulmonary bypass system: a prospective randomized study. Innovations. 2012;7:23-32.

Summers KL and Bhagirath Singh.  Gut microbes and regulatory Th17 cells in Type 1 diabetes. Immunotherapy (2012) 4(4), 363–364.

Non-genetic mechanisms communicating antibiotic resistance: rethinking strategies for antimicrobial drug design. El-Halfawy OM, Valvano MA. Expert Opin Drug Discov. 2012 Aug 4. [Epub ahead of print]

Burkholderia cenocepacia Type VI Secretion System Mediates Escape of Type II Secreted Proteins into the Cytoplasm of Infected Macrophages. Rosales-Reyes R, Aubert DF, Tolman JS, Amer AO, Valvano MA.
PLoS One. 2012;7(7):e41726. Epub 2012 Jul 25.

The Burkholderia cenocepacia sensor kinase hybrid AtsR is a global regulator modulating quorum-sensing signalling. Aubert DF, O'Grady EP, Hamad MA, Sokol PA, Valvano MA.
Environ Microbiol. 2012 Jul 3. doi: 10.1111/j.1462-2920.2012.02828.x. [Epub ahead of print]

Characterization of the highly conserved VFMGD motif in a bacterial polyisoprenyl-phosphate N-acetylaminosugar-1-phosphate transferase. Furlong SE, Valvano MA. Protein Sci. 2012 Jul 18. doi: 10.1002/pro.2123. [Epub ahead of print]

High confidence prediction of essential genes in burkholderia cenocepacia. Juhas M, Stark M, von Mering C, Lumjiaktase P, Crook DW, Valvano MA, Eberl L. PLoS One. 2012;7(6):e40064.

Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance in Burkholderia cenocepacia(†). Hamad MA, Di Lorenzo F, Molinaro A, Valvano MA. Mol Microbiol. 2012 Jun 28. doi: 10.1111/j.1365-2958.2012.08154.x. [Epub ahead of print]

Schmerk, C.L, and M.A. Valvano*. 2012. Burkholderia multivorans survival and trafficking in macrophages. Journal of Medical Microbiology (in press).

Abdulrahman, B.A, A.A. Khweek, A. Akhter, K. Caution, M.T.H. Hassan, Y. Zhang, P.D. Rowland, S. Malhotra, F. Aeffner, I.C. Davis, M.A. Valvano, and A.O. Amer. 2012. Depletion of the ubiquitin binding adaptor molecule SQSTM1/p62 from macrophages harboring the cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery. Journal of Biological Chemistry (in press).

Lee, T-W., T.B. Verhey, P.A. Antiperovitch, D. Atamanyuk, N.Desroy, C. Oliveira, A. Denis, V. Gerusz, E. Drocourt, S.A. Loutet, M. Hamad, C. Stanetty, S.N. Andres, S. Sugiman-Marangos, P. Kosma, M.A. Valvano, F. Moreau, M.S. Junop. 2012. Structure, function and inhibition of D-glycero-β-D-manno-Heptose 7-Phosphate Kinase (HldA) from Burkholderia cenocepacia: insights for design of antivirulence drugs and antibiotic adjuvants targeting LPS biosynthesis in Gram-negative bacteria. Journal of Medicinal Chemistry (in press).


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