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Publication Archive:

This is a select list of our publications, access the Researcher's home page for a complete listing of their publications

2013

 

Heit et al., Multimolecular Signaling Complexes Enable Syk-Mediated Signaling of CD36 Internalization, Developmental
Cell (2013), http://dx.doi.org/10.1016/j.devcel.2013.01.007

Genetically modified VSVNJ vector is capable of accommodating a large foreign gene insert and allows high level gene expression. C.Y., Kang et. al. Virus Research, Volume 171, Issue 1, January 2013, Pages 168–177

"p62/SQSTM1 enhances NOD2-mediated signaling and cytokine production through stabilizing NOD2 oligomerization" Sangwook Park, Soon-Duck Ha, Macon Coleman, Shahab Meshkibaf, Sung Ouk Kim. PLoS One 2013 Feb. in press.

Mateusz Rytelewski, Peter J. Ferguson, Saman Maleki Vareki, Rene Figueredo, Mark Vincent, James Koropatnick. "Inhibition of BRCA2 and thymidylate synthase creates multi-drug sensitive tumor cells via induction of combined 'complementary lethality'." Molecular Therapy - Nucleic Acids (In press February 2013)

"To invade or not to invade:  two approaches to a prokaryotic predatory life cycle." Ryan Chanyi, Caitlin Ward, Andrea Pechey and Susan Koval.  Canadian Canadian Journal of Microbiology, 10.1139/cjm-2013-0041.

MacPhee, R., W. L. Miller, G. B. Gloor, J. K. McCormick, J. P. Burton, G. Reid. 2013. Influence of vaginal microbiota on toxic shock syndrome toxin-1 production by Staphylococcus aureus. Applied and Environmental Microbiology. 79(6):1835-42.

The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia. Sass AM, Schmerk C, Agnoli K, Norville PJ, Eberl L, Valvano MA, Mahenthiralingam E. ISME J. 2013 Mar 14. doi: 10.1038/ismej.2013.36.

 

2012

Hattlmann, C.J., Kelly, J.N. and Barr, S.D. TRIM22: A diverse and dynamic antiviral protein. Molecular Biology International. Volume 2012 (2012), Article ID 153415.

Effect of environmental stress factors on the uptake and survival of Campylobacter jejuni in Acanthamoeba castellanii. Xuan Thanh Bui, Klaus Qvortrup, Anders Wolff, Dang Duong Bang and Carole Creuzenet. BMC Microbiology 2012, 12:232 

Complete 6-deoxy-D-altro-heptose biosynthesis pathway from Campylobacter jejuni: more complex than anticipated. McCallum M, Shaw SD, Shaw GS, Creuzenet C. J Biol Chem. 2012 Jul 11. [Epub ahead of print]

Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia. Xu, L. S., Sokalski, K. M., Hotke, K., Christie, D. A., Zarnett, O., Piskorz, J., Thillainadesan, G., Torchia, J., and DeKoter, R. P. 2012. Journal of Immunology, in press.

Noel G., DeKoter R., Wang Q., Hexley P., Ogle CK. Optimization and application of a flow cytometric PU.1 assay for murine immune cells. Journal of Immunological Methods 2012 May 11 [Epub ahead of print].

Peyer’s patch M cells derived from Lgr5+ stem cells require Spi-B and are induced by RankL in cultured ‘miniguts’. De Lau, W., Kujala, P., Schneeberger, K., Middendorp, S., Li, V. S. W., Barker, N., Martens, A., Hofhuis, F., DeKoter, R. P., Peter, P. J., Nieuwenhuis, E., Clevers, H. Molecular and Cellular Biology 18:3639-47, 2012.

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I. Dikeakos JD, Thomas L, Kwon G, Elferich J, Shinde U, Thomas G. Mol Biol Cell. 2012 Jun;23(11):2184-97. Epub 2012 Apr 11. PMID: 22496420 [PubMed - in process]

Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2). Werneburg NW, Bronk SF, Guicciardi ME, Thomas L, Dikeakos JD, Thomas G, Gores GJ. J Biol Chem. 2012 May 29. [Epub ahead of print] PMID: 22645134 [PubMed - as supplied by publisher]

Kulkarni R, Villanueva AI, Elawadli I, Jayanth P, Read LR, Haeryfar SM, Sharif S: Costimulatory activation of murine invariant natural killer T cells by Toll-like receptor agonists. Cellular Immunology 2012 (in press)

Cheung, J., M.E.P. Murphy and D.E. Heinrichs.  2012. Discovery of an iron-regulated citrate synthase in Staphylococcus aureus. Chemistry & Biology. 19: 1568-1578.

Robust induction of the staphylococcal proteolytic cascade by unsaturated antimicrobial fatty acids in the USA300 strain of community acquired methicillin resistant Staphylococcus aureus.  Arsic, B., Y. Zhu, D.E. Heinrichs and M.J. McGavin. 2012. PLOS One.  Epub Sept 24.

The multi-protein heme shuttle pathway in Staphylococcus aureus: Isd cog-wheel kinetics. Tiedemann, M.T., D.E. Heinrichs and M.J. Stillman. 2012. J. Am. Chem. Soc.  Epub Sept 17.

Sheldon JR and Heinrichs DE (2012) The iron-regulated staphylococcal lipoproteins. Front. Cell. Inf. Microbio. 2:41. Published online: 04 April 2012.

Genetically modified VSVNJ vector is capable of accommodating a large foreign gene insert and allows high level gene expression. C.Y., Kang et. al. Virus Research accepted for publication

Cellular Adaptation to Anthrax Lethal Toxin-Induced Mitochondrial Cholesterol Enrichment, Hyperpolarization, and ROS Generation through Down-regulating MLN64 in Macrophages. Ha SD, Park S, Han CY, Nguyen ML, Kim SO. Mol Cell Biol. 2012 Oct 1. [Epub ahead of print] PMID: 23028046

Reduction of tumorigenicity by placental extracts. Marleau AM, McDonald G, Koropatnick J, Chen CS, Koos D. Anticancer Res. 2012 Apr;32(4):1153-61.

Susan F. Koval, Sandra H. Hynes, Ronald S. Flannagan, Zohar Pasternak, Yaacov Davidov, and Edouard Jurkevitch Bdellovibrio exovorus sp. nov., a novel predator of Caulobacter crescentus Int J Syst Evol Microbiol ijs.0.039701-0; published ahead of print February 24, 2012, doi:10.1099/ijs.0.039701-0

Xu SX and McCormick J (2012). Staphylococcal superantigens in colonization and disease. Front. Cell. Inf. Microbio. 2:52. doi: 10.3389/fcimb.2012.00052

McGavin MJ, Arsic B and Nickerson NN (2012). Evolutionary blueprint for host- and niche-adaptation in Staphylococcus aureus clonal complex CC30. Front. Cell. Inf. Microbio. 2:48. doi: 10.3389/fcimb.2012.00048

The staphylococci and staphylococcal pathogenesis. McGavin, M.J. and D.E. Heinrichs. 2012. Front. Cell. Infect. Microbiol. 2: 66

Conserved region 3 of human papillomavirus 16 E7 contributes to deregulation of the retinoblastoma tumor suppressor. Biljana Todorovic, Katherine Hung, Paola Massimi, Nikita Avvakumov, Frederick A. Dick, Gary S. Shaw, Lawrence Banks and Joe S. Mymryk. Published ahead of print 26 September 2012, doi: 10.1128/JVI.01637-12

Frequent Mutations in TP53 and CDKN2A Found by Next-Generation Sequencing of Head and Neck Cancer Cell Lines. Nichols AC, Yoo J, Palma DA, Fung K, Franklin JH, Koropatnick J, Mymryk JS, Batada NN, Barrett JW. Arch Otolaryngol Head Neck Surg. 2012 Aug 1;138(8):732-9.

Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. Jai Ablack, Michael Cohen, Gobi Thillainadesan, Gregory J. Fonseca, Peter Pelka, Joe Torchia, and Joe S. Mymryk. J. Virology, May 2012

G.J. Fonseca, G. Thillainadesan, A.F. Yousef, J.N. Ablack, K.L. Mossman, J. Torchia, J.S. Mymryk. Adenovirus Evasion of Interferon-Mediated Innate Immunity by Direct Antagonism of a Cellular Histone Posttranslational Modification.  Cell Host & Microbe, Volume 11, Issue 6, 597-606, 14 June 2012

TGF-β-Dependent Active Demethylation and Expression of the p15(ink4b) Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex. Thillainadesan G, Chitilian JM, Isovic M, Ablack JN, Mymryk JS, Tini M, Torchia J. Mol Cell. 2012 May 2. [Epub ahead of print]

Ki-67 expression predicts radiotherapy failure in early glottic cancer. Nichols AC, Whelan F, Basmaji J, Dhaliwal S, Dowthwaite S, Chapeskie C, Read N, Palma DA, Fung K, Venkatesan V, Alex Hammond J, Franklin JH, Siddiqui I, Wehrli B, Kwan K, Koropatnick J, Mymryk JS, Barrett JW, Yoo J. J Otolaryngol Head Neck Surg. 2012 Apr 1;41(2):124-30.

Yousef AF,FonsecaGJ, Cohen MJ,MymrykJS. The C-terminal region of E1A: A molecular too for cellular cartography. Biochem Cell Biol. 2012 Jan 31. [Epub ahead of print]

Adhesion of Lactobacillus iners AB-1 to Human Fibronectin: A Key Mediator for Persistence in the Vagina? McMillan A, Macklaim JM, Burton JP, Reid G. Reprod Sci. 2012 Nov 30. [Epub ahead of print]

Micronutrient supplemented probiotic yogurt for HIV-infected adults taking HAART in London, Canada. Hemsworth JC, Hekmat S, Reid G. Gut Microbes. 2012 Sep-Oct;3(5):414-9.

HPV Type Distribution and Cervical Cytology among HIV-Positive Tanzanian and South African Women. Dols JA, Reid G, Brown JM, Tempelman H, Bontekoe TR, Quint WG, Boon ME. ISRN Obstet Gynecol. 2012;2012:514146. 

Probiotic interference of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 with the opportunistic fungal pathogen Candida albicans. Köhler GA, Assefa S, Reid G. Infect Dis Obstet Gynecol. 2012;2012:636474. 

A Canadian Working Group report on fecal microbial therapy: microbial ecosystems therapeutics. Allen-Vercoe E, Reid G, Viner N, Gloor GB, Hota S, Kim P, Lee C, O'Doherty K, Vanner SJ, Weese JS, Petrof EO. Can J Gastroenterol. 2012 Jul;26(7):457-62. 

Bioremediation and tolerance of humans to heavy metals through microbial processes: a potential role for probiotics? Monachese M, Burton JP, Reid G. Appl Environ Microbiol. 2012 Sep;78(18):6397-404. 

Breast, milk and microbes: a complex relationship that does not end with lactation. Urbaniak C, Burton JP, Reid G. Womens Health (Lond Engl). 2012 Jul;8(4):385-98.

Macklaim JM, Cohen CR, Donders G, Gloor GB, Hill JE, Parham GP, Ravel J, Spear G, van de Wijgert J, Reid G. Exploring a Road Map to Counter Misconceptions About the Cervicovaginal Microbiome and Disease. Reprod Sci. 2012 May 21.

Adhesion Forces and Coaggregation between Vaginal Staphylococci and Lactobacilli. Jessica A. Younes, Henny C. van der Mei, Edwin van den Heuvel, Henk J. Busscher, Gregor Reid. PLoS ONE.

Whaling, M., I. Luginaah, G. Reid, S. Hekmat, A. Thind, J. Mwanga, and J. Changalucha. 2011. Perceptions of probiotic yogurt for health and nutrition in the context of HIV/AIDS in Mwanza, Tanzania. J. Health Popul. Nutr. In press

Kiaii B, Fox S, Swinamer SA, Rayman R, Higgins J, Cleland A, Fernandes P, Macdonald J, Dobkowski WB, Stitt LW, Novick RJ, Singh B, Bureau Y, Summers K. The early inflammatory response in a mini-cardiopulmonary bypass system: a prospective randomized study. Innovations. 2012;7:23-32.

Summers KL and Bhagirath Singh.  Gut microbes and regulatory Th17 cells in Type 1 diabetes. Immunotherapy (2012) 4(4), 363–364.

Non-genetic mechanisms communicating antibiotic resistance: rethinking strategies for antimicrobial drug design. El-Halfawy OM, Valvano MA. Expert Opin Drug Discov. 2012 Aug 4. [Epub ahead of print]

Burkholderia cenocepacia Type VI Secretion System Mediates Escape of Type II Secreted Proteins into the Cytoplasm of Infected Macrophages. Rosales-Reyes R, Aubert DF, Tolman JS, Amer AO, Valvano MA.
PLoS One. 2012;7(7):e41726. Epub 2012 Jul 25.

The Burkholderia cenocepacia sensor kinase hybrid AtsR is a global regulator modulating quorum-sensing signalling. Aubert DF, O'Grady EP, Hamad MA, Sokol PA, Valvano MA.
Environ Microbiol. 2012 Jul 3. doi: 10.1111/j.1462-2920.2012.02828.x. [Epub ahead of print]

Characterization of the highly conserved VFMGD motif in a bacterial polyisoprenyl-phosphate N-acetylaminosugar-1-phosphate transferase. Furlong SE, Valvano MA. Protein Sci. 2012 Jul 18. doi: 10.1002/pro.2123. [Epub ahead of print]

High confidence prediction of essential genes in burkholderia cenocepacia. Juhas M, Stark M, von Mering C, Lumjiaktase P, Crook DW, Valvano MA, Eberl L. PLoS One. 2012;7(6):e40064.

Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance in Burkholderia cenocepacia(†). Hamad MA, Di Lorenzo F, Molinaro A, Valvano MA. Mol Microbiol. 2012 Jun 28. doi: 10.1111/j.1365-2958.2012.08154.x. [Epub ahead of print]

Schmerk, C.L, and M.A. Valvano*. 2012. Burkholderia multivorans survival and trafficking in macrophages. Journal of Medical Microbiology (in press).

Abdulrahman, B.A, A.A. Khweek, A. Akhter, K. Caution, M.T.H. Hassan, Y. Zhang, P.D. Rowland, S. Malhotra, F. Aeffner, I.C. Davis, M.A. Valvano, and A.O. Amer. 2012. Depletion of the ubiquitin binding adaptor molecule SQSTM1/p62 from macrophages harboring the cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery. Journal of Biological Chemistry (in press).

Lee, T-W., T.B. Verhey, P.A. Antiperovitch, D. Atamanyuk, N.Desroy, C. Oliveira, A. Denis, V. Gerusz, E. Drocourt, S.A. Loutet, M. Hamad, C. Stanetty, S.N. Andres, S. Sugiman-Marangos, P. Kosma, M.A. Valvano, F. Moreau, M.S. Junop. 2012. Structure, function and inhibition of D-glycero-β-D-manno-Heptose 7-Phosphate Kinase (HldA) from Burkholderia cenocepacia: insights for design of antivirulence drugs and antibiotic adjuvants targeting LPS biosynthesis in Gram-negative bacteria. Journal of Medicinal Chemistry (in press).

 

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