Evidence-Based Neurology
CATEGORY: Infection
Early
Treatment with Dexamethasone Improved Outcome in Adults with Acute Bacterial
Meningitis
Date appraised: April 2008
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In suspected sporadic
CJD, the diagnostic sensitivity and specificity of MRI was 67% and 93% respectively
Date appraised: May 2005
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Age, anemia, opportunistic
infection, and low CD4 counts increased the risk of HIV dementia
Date appraised: April 2005
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IV
dexamethasone decreased the risk of hearing loss in children with bacterial
meningitis. The evidence was less convincing for decreasing unfavourable outcomes
in adults.
Date appraised: January 2004
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Acyclovir
was superior to Vidarabine in the treatment of biopsy-proven HSV encephalitis.
Date appraised: February 2003
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In healthy adults
with suspected meningitis clinical features ruled out significant abnormalities
on cranial CT. This clinical decision rule about CT before LP
has yet to be validated
Date appraised: December 2002
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Cerebrospinal fluid
14𣛩 protein testing was highly sensitive and specific for patients
with a clinical suspicion of Creutzfeldt-Jakob disease
Date appraised: June 2002
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In clinically suspected
CJD, an EEG with periodic sharp waves significantly increases
the probability of CJD. Their absence do not rule out CJD.
Date appraised: December 1999
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