Evidence-Based Neurology
CATEGORY: Critical Care

In patients with anoxic encephalopathy, absent SSEPs, absent pupil reflexes, or no response to pain at 72 hours, independently predicted death or vegetative state with 100% specificity
Date appraised: July 2001
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In the treatment of status epilepticus, there was no significant difference in outcomes with lorazepam, diazepam plus phenytoin, or phenobarbital.
Date appraised: October 2000
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In highly selected patients, thrombolysis reduced the overall death and dependency rate in acute ischemic stroke.
Date appraised: September 2000
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For acute spinal cord compression due to epidural metastasis extremely weak evidence suggests that decompressive surgery was statistically different from radiotherapy alone with respect to maintained or regained ambulatory status.
Date appraised: March 2000
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In cerebral edema following stroke, both mannitol and hypertonic saline may reduce raised intracranial pressure acutely.
Date appraised: November 1998
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In highly selected patients, intravenous t-PA given within 3 hours of ischemic stroke onset improves outcome and mortality.
Date appraised: August 1998
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IVIg is at least as effective and perhaps superior to Plasma Exchange in the treatment of patients with acute non-bulbar Guillain-Barre Syndrome.
Date appraised: August 1998
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