Brian L. PagenkopfBrian L. Pagenkopf
B.Sc. University of Minnesota
Ph.D. Montana State University
Postdoc Caltech and ETH
Office: Rm 2020 BGS, Lab Rms 210 ChB and 2008 BGS
Phone (Office): +1 519 661-2111 ext 81430
Phone (Lab): +1 519 661-2111 ext 81589

Research Group Homepage

Synthetic Organic


    College of Natural Sciences Teaching Excellence Award
    Department of Defense New Investigator Award
    NSERC Discovery Accelerator Supplement

Current Research Programs:

The Pagenkopf group is engaged in a variety of reaction discovery, methodology development and natural products/functional materials synthesis projects. Our long term objectives for new transformations is to bring them to a sufficient state of maturity that they find use in the standard repertoire of synthetic chemistry. We use natural products to contextualize representative substrates to ensure synthetic relevancy, and in turn some of these become targets for total synthesis. We have a multidisciplinary research program with expertise in cyclopropanes, epoxide reactions, THF synthesis, asymmetric catalysis and siloles.

Selected Publications and Publications Database:

BF2OBn.OEt2: A Novel Lewis Acid and its use in a Regio- and Stereo-selective Opening of Trisubstituted Epoxides and its Application Towards Amphidinolide C and F. Nicholas A. Morra and Brian L. Pagenkopf, Eur. J. Org. Chem. 2013, 756–760.

Formal [4+2] Cycloaddition of Alkoxy-Substituted Donor-Acceptor Cyclobutanes and Aldehydes Catalyzed by Yb(OTf)3. Mahmoud M. Abd Rabo Moustafa, Andrew C. Stevens, Ben P. Machin and Brian L. Pagenkopf, Org. Lett. 2010, 12, 4736–4738.

Diels-Alder Chemistry of Siloles and their Transformation into Cyclohex-2-ene-1,4-cis-diols. Andrew C. Stevens and Brian L. Pagenkopf, Org. Lett. 2010, 12, 3658–3661.

Improved Yields and Simplified Purification with a Second Generation Cobalt Catalyst for the Oxidative Formation of trans-THF Rings. Cory Palmer, Nicholas A. Morra, Andrew C. Stevens, Barbora Bajtos, Benjamin P. Machin and Brian L. Pagenkopf, Org. Lett. 2009, 11, 5614—5617.

Total Synthesis of (±)-Quebrachamine via [3+2] Cycloaddition and Chloroacetamide Photocyclization. Barbora Bajtos and Brian L. Pagenkopf, Eur. J. Org. Chem. 2009, 1072-1077.

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