François Lagugné-Labarthet
Assistant Professor
Ph.D., Université Bordeaux
Office: MSA 0202. Lab: Not available
Phone (Office): 519 661-2111 ext 81006
flagugne@uwo.ca
Research Group Homepage

Microscopic and Spectroscopic Characterization of Nanomaterials

Current Research Programs:

The past decade has seen rapid developments in the fields of "nanoscience” and “nanotechnology”. Although the potential applications derived from nano-objects are promising, such as bit-elements in super-computers, molecular receptors capable of trapping and detecting air or water pollutants, and drug delivery carriers, the potential nanosciences holds has yet to be fulfilled. In this context, the characterization of these nano-objects or functionalized surfaces using spectroscopic methods combined with advanced microscopy techniques offers information far beyond that provided by pure imaging techniques as it allows the molecular properties of these materials to be correlated with their molecular structures, sizes and compositions.

Our program combines state-of-the-art scanning probe microscopies with Raman and Sum-Frequency Generation (SFG) vibrational spectroscopies. Enhancement effects coming from metallic particles or electronic resonances will be used to achieve high detection sensitivities. One goal in F.L.L group is to develop new versatile vibrational techniques that surpass conventional optical microscopes in terms of spatial resolution and sensitivity. Such techniques will be used to (i) determine confinement effects in nanomaterials, (ii) dynamically measure the change in conformation of molecular systems under various stimuli, (iii) evaluate chemical interactions and dynamical processes in biomolecules, and (iv) develop ultrasensitive vibrational technique for single molecule detection.

Potential graduate students who have interests in material science, biomaterials,  nanoscience, optical spectroscopy and near-field microscopies are welcome to contact him.

 

Selected Publications:

B. Galarreta, E. Harté, N. Marquestaut, P. Norton, F. Lagugné-Labarthet*, "Plasmonic Properties of Fisher's Patterns: Polarization effects”, Phys Chem Chem. Phys, 2010, in press.

S. Varma, J. McLachlan, A. M. Leclair, B. Galarreta, P. R. Norton, F. Lagugné-Labarthet,* “Positional Encoding of Living Cells with Fluorinated Patterned Surfaces”, Analytical and Bioanalytical Chemistry, 2010, 396, 1159-1165.

C. Séguin, J. McLachlan, P. R. Norton, F. Lagugné-Labarthet* , “Surface Modification of Poly(dimethyl siloxane) for Microfluidic Assay Applications”, Applied Surface Science, 2010, 256, 2524-2531.

V. Guieu, P. Garrigue, F. Lagugné-Labarthet,*, L. Servant, N. Sojic, D.Talaga, “Remote Tip-Enhanced Raman Spectroscopy Imaging via a Nanostructured Optical Fiber Bundle”, Optics Express, 2009, 17, 24030-24035.

V. Guieu, D. Talaga, L. Servant, N. Sojic* and F. Lagugné-Labarthet* , “Multitip-Localized Enhanced Raman Scattering from a Nanostructured Optical Fiber Array” J. Phys. Chem. C, 2009, 113 (3), pp 874–881.