François Lagugné-LabarthetFrançois Lagugné-Labarthet
Associate Professor
Ph.D., Université Bordeaux
Office: MSA 0202. Lab: Not available
Phone (Office): 519 661-2111 ext 81006

Research Group Homepage

Microscopic and Spectroscopic Characterization of Nanomaterials

Current Research Programs:

Although the past decade has seen rapid developments in the application of nanosized materials such as biological sensors, flexible solar cells, drug delivery carriers, or bit elements in computers, the potential nanoscience holds has yet to be fulfilled. In this context, the characterization of these nano-objects or functionalized surfaces using optical spectroscopy combined with advanced microscopy techniques offers information far beyond that provided by pure imaging techniques as it allows the molecular properties of these materials to be correlated with their molecular structures, sizes and compositions.

Our program focuses on the study of materials and biomaterials organized at the nano- and micro-scales using a combination of scanning probe microscopy together with a variety of high resolution optical microscopy techniques (Raman, Fluorescence). We are also making use of a state-of-the-art nanofabrication  Facility at Western (, Director: F.Lagugné-Labarthet)  to design, fabricate and characterize original  nanostructures with the aim to surpass the diffraction limit of light.

Such an ensemble of complementary approaches are used  to (i)  probe materials and biomaterials  at the hundreds of nanometers scale resolution, (ii) perform ultrasensitive vibrational measurements in conjunction with plasmonic platforms made in our labs to enhance the detection limit through surface enhancement effects (iii) modify surfaces to direct the growth of cells and evaluate the chemical exchanges between them at the single cell level in real-time.

We are always looking for passionate graduate students who have interests in nanoscience and instrumental developments in spectroscopy and microscopy.

Selected Publications:

“Mechanism of inhibition of calcium oxalate crystal growth by an osteopontin phosphopeptide”, S.Hug , B. Grohe , J.Jalkanen , B. Chan , B. Galarreta , K. Vincent , F. Lagugné-Labarthet , G. Lajoie , Harvey A. Goldberg , M.Karttunen and G. K. Hunter*, Soft Matter, 2012, 8,  1226-1233.

"Mapping Hot-Spots in hexagonal Arrays of Metallic Nanotriangles", B.Galarreta, I.Rupar, A.Young, F. Lagugné-Labarthet*, J. Phys. Chem. C, 2011, 115, 15318-15323.

"Covalently Assembled Gold Nanoparticle-Carbon Nanotube Hybrids via a Photoinitiated Carbene Addition Reaction", H.Ismaili, F. Lagugné-Labarthet, and M. S. Workentin*, Chem. Mater., 2011, 23, 1519-1525.

"SERS Detection of Streptavidin/Biotin Monolayer Assemblies", B.C. Galarreta, P.R. Norton, and F. Lagugné-Labarthet*, Langmuir, 2011, 27, 1494–1498 .

"Surface patterning using plasma-deposited fluorocarbon thin films for single-cell positioning and neural circuit arrangement", A. Leclair, S. Ferguson, F.Lagugné-Labarthet*, Biomaterials, 2011, 32, 1351-1360 .


Western provides the best student experience among Canada's leading research-intensive universities.