Brain and Mind Institute

Core Members

There are currently 34 core members leading research activities at the Brain and Mind Institute. Click on a name below or scroll down the page to learn more about their research areas and contact information.



Daniel Ansari

Daniel Ansari

Contact Information

Tel: (519) 661-2111 x80548
Email: daniel.ansari@uwo.ca
Website: Numerical Cognition Laboratory

Department

Psychology

Research Areas

  • Developmental Cognitive Neuroscience
  • Mind, Brain and Education
  • Development of numerical and mathematical skills
  • Developmental Dyscalculia

Publications

Merkley, R. & Ansari, D. (in press) Why numerical symbols count in the development of mathematical skills: evidence from brain and behaviour. Current Opinions in Behavioral Sciences.
Bugden, S. & Ansari, D. (in press) Probing the nature of deficits in the ‘Approximate Number System’ in children with persistent Developmental Dyscalculia. Developmental Science
Alcock, L., Ansari, D., Batchelor, S., Bisson, Marie-J., De Smedt, B., Gilmore, C., Göbel, S., Hannula-Sormunen, M., Hodgen, J., Inglis, M., Jones, I., Mazzocco, M., McNeil, N., Schneider, M., Simms, V. & Weber, K. (in press). Challenges in Mathematical Cognition: A Collaboratively-Derived Research Agenda. Journal of Numerical Cognition.
Vanbinst, K., Ansari, D., Ghesquière, P. & De Smedt, B. (2016) Symbolic numerical magnitude processing is as important to arithmetic as phonological awareness is to reading. PLoS ONE, 11(3)e0151045
Matejko, A.A. & Ansari, D (2016) Trajectories of symbolic and nonsymbolic magnitude processing in the first year of formal schooling. PLoS ONE,11(3)e0149863
Leibovich, T. & Ansari, D. (2016) The symbol-grounding problem in numerical cognition: a review of theory, evidence and outstanding questions. Canadian Journal of Experimental Psychology (Special Section on Numerical Cognition, edited by Jamie Campbell), 70:12-23.
Goffin, C. & Ansari, D. (2016) Beyond magnitude: Judging ordinality of symbolic number is unrelated to magnitude comparison and independently relates to individual differences in arithmetic. Cognition, 150, 68-76.
Leibovich, T., Vogel, S.E., Henik, A. & Ansari, D. (2016) Asymmetric processing of numerical and non-numerical magnitudes in the brain: an fMRI study. Journal of Cognitive Neuroscience, 28, 166-76.
Lyons, I.M. & Ansari, D. (2015) Numerical Order Processing in Children: From Reversing the Distance-Effect to Predicting Arithmetic. Mind, Brain and Education, 9, 207-21.
Lyons, I.M., Nuerk, H.C. & Ansari, D. (2015) Rethinking the implications of numerical ratio effects for understanding the development of representational precision and numerical processing across formats. Journal of Experimental Psychology: General, 144, 1021-35.

Funding

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Robert Bartha

Rob Bartha

Contact Information

Tel: (519) 663-5777 x24039
Email: rbartha@robarts.ca
Website: Bartha Group

Department

Medical Biophysics, Medical Imaging, Psychiatry

Research Areas

  • The development of high-field magnetic resonance imaging (MRI)
  • Spectroscopy techniques for early diagnosis of disease and monitoring of treatment response

Publications

D Bernier, R Bartha, D McAllindon, CC Hanstock, Y Marchand, KN Dillen, M Gallant, KP Good, PG Tibbo. Illness Versus Substance Use Effects on The Frontal White Matter in Early Schizophrenia: A 4Tesla 1H-MRS Study. Schizophr Res. [Epub ahead of print.] May 2016.
S Nikolova, R Bartha, AG Parrent, DA Steven, D Diosy, JG Burneo. ¬¬¬¬Functional MRI of Neuronal Activation in Epilepsy Patients with Malformations of Cortical Development. Epilepsy Research. 116 1-7, Oct 2015. PubMed ID: 26354161.
M Suchy, M Milne, A Elmehriki, N McVicar, A Li, R Bartha, R Hudson. Introduction of peripheral carboxylates to decrease the charge on Tm3+ DOTAM-alkyl complexes: Implications for de-tection sensitivity and in vivo toxicity of PARACEST MRI contrast agents. Journal of Medicinal Chemistry. 58(16) 6516-6532, Aug 2015. PubMed ID: 26214576.
JA Snir, M Suchy, K St. Lawrence, RHE Hudson, SH Pasternak, R Bartha. Prolonged in-vivo retention of a Cathepsin D targeted optical contrast agent in a mouse model of Alzheimer’s disease. Journal of Alzheimer's Disease. 48(1) 73-87, Aug 2015. PubMed ID: 26401930.
A Farag, JC Peterson, T Szekeres, G Bauman, J Chin, C Romagnoli, R Bartha, TJ Scholl. Unshielded asymmetric transmit-only and endorectal receive-only radiofrequency coil for (23) Na MRI of the prostate at 3 tesla. Journal of Magnetic Resonance Imaging. 42(2) 436-445, Aug 2015. P¬ubMed ID: 26354161.
J Penner, R Bartha. Semi-LASER H-1 MR spectroscopy at 7 Tesla in human brain: Metabolite quantification incorporating subject-specific macromolecule removal. Magnetic Resonance in Medicine. 74(1) 4-12, Jul 2015. PubMed ID: 25081993.
C Annweiler, R Bartha, S Goncalves, SN Karras, P Millet, F Feron, O Beauchet. Vitamin D-related changes in intracranial volume in older adults: A quantitative neuroimaging study. Maturitas 80(3) 312-317, Mar 2015. PubMed ID: 25614220.
C Annweiler, R Bartha, SN Karras, J Gautier, F Roche, O Beauchet. Vitamin D and white matter abnormalities in older adults: A quantitative volutmetric analysis of brain MRI. Experimental Gerontology 63 41-47, Mar 2015. PubMed ID: 25645292
M Lewis, M Milne, R Bartha, RHE Hudson. Dysprosium(III) and thulium(III) complexes of DO3A-monoanilides: an investigation of electronic effects on their relaxometric and amide-based PARACEST properties. Canadian Journal of Chemistry 93(2) 244-252, Feb 2015.
J Penner, JL Wells, MJ Borrie, SM Woolmore-Goodwin, R Bartha. Reduced N-Acetylaspartate to Creatine Ratio in the Posterior Cingulate Correlates with Cognition in Alzheimer's Disease following Four Months of Rivastigmine Treatment. Dementia and Geriatric Cognitive Disorders 39(1-2) 68-80, Jan 2015. PubMed ID: 25358336

Funding

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Tim Bussey

Tim Bussey

Contact information

Tel: (519) 661-2111 x83452
Email: tbussey@uwo.ca  
Website: TCNLab

Department

Physiology & Pharmacology, Psychiatry

Research Areas

  • Cognition, how the healthy brain does it, what goes wrong in neurodegenerative and neuropsychiatric disease, and identifying targets for therapy
  • Improving preclinical-to-clinical translation

Selected Publications

Bekinschtein, P., Kent, B.A., Oomen, C.A., Clemenson, G.D., Gage, F.H., Saksida, L.M. & Bussey, T.J. (2013) BDNF in the dentate gyrus is required for consolidation of "pattern-separated" memories. Cell Reports, 5: 759-768. PMCID: PMC3898274
Mar, A.C., Horner, A.E., Nilsson, S., Alsiö, J., Kent, B.A., Kim, C.H., Holmes, A., Saksida, L.M., & Bussey, T.J. (2013) The touchscreen operant platform for assessing executive function in rats and mice. Nature Protocols, 8(10):1985-2005.
Oomen, C.A., Hvoslef-Eide, M., Heath, C.J., Mar, A.C., Horner, A.E., Bussey, T.J., & Saksida, L.M. (2013) The touchscreen operant platform for testing working memory and pattern separation in rats and mice. Nature Protocols, 8(10):2006-21. PMCID: PMC3982138
Horner, A.E., Heath, C.J., Hvoslef-Eide, M., Kent, B.A., Kim, C.H., Nilsson, S., Alsiö, J., Oomen, C.A., Holmes, A., Saksida, L.M., & Bussey, T.J. (2013) The touchscreen operant platform for testing learning and memory in rats and mice. Nature Protocols, 8(10):1961-84. PMCID: PMC3914026
Nithianantharajah, J, Komiyama N.H., McKechanie, A., Johnstone, M., Blackwood D.H., St Clair, D., Emes R.D., van de Lagemaat L.N., Saksida L.M., Bussey T.J. * & Grant, S.G.N. * (2013) Synaptic scaffold evolution generated components of vertebrate cognitive complexity, Nature Neuroscience, 16 (1): 16-24
Graybeal, C., Feyder, M., Schulman, E., Saksida, L.M., Bussey, T.J., Brigman, J.L. & Holmes, A. (2011) Moderate stress or prefrontal damage facilitates reversal learning: rescue by prefrontal-infused BDNF. Nature Neuroscience, 14(12):1507-9. Recommended by Faculty of 1000 as “Must Read”, see www.facultyof1000.com
Creer, D., Romberg C., Saksida L.M., van Praag, H., Bussey T.J. (2010) Running enhances spatial pattern separation in mice. Proc Natl Acad Sci U S A 107(5):2367-72
Clelland C.D., Choi M., Romberg C., Clemenson G.D. Jr., Tyers P., Jessberger S., Saksida L.M., Barker R.A., Gage F.H., Bussey T.J. (2009) A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science, 325 (5937): 210-213. Recommended by Faculty of 1000 as “Must Read”, see www.facultyof1000.com. Featured as a “Research Highlight” in Nature Reviews Neuroscience 10: 622 - 623 (2009)
Bartko, S.J., Winters, B.D., Cowell, R., Saksida, L.M., & Bussey, T.J. (2007). Perceptual impairments following perirhinal cortex lesions in rats: zero-delay object recognition and simultaneous oddity discriminations. Journal of Neuroscience, 27(10), 2548-2559
Winters, B.D., Saksida, L.M., & Bussey, T.J. (2006). Paradoxical facilitation of object recognition memory following infusion of scopolamine into perirhinal cortex: implications for cholinergic system function. Journal of Neuroscience, 26, 9520-9529
Winters, B.D., & Bussey, T.J. (2005). Transient inactivation of perirhinal cortex disrupts encoding, retrieval, and consolidation of object recognition memory. Journal of Neuroscience, 25:52-61
Winters, B.D., & Bussey, T.J. (2005). Glutamate receptors in perirhinal cortex mediate encoding, retrieval, and consolidation of object recognition memory. Journal of Neuroscience, 25:4243-4251
Winters, B. D., Forwood, S. E., Cowell, R. A., Saksida, L. M., & Bussey, T. J. (2004). Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: Heterogeneity of function within the temporal lobe. Journal of Neuroscience, 24, 5901-5908
Bussey, T. J., Saksida, L.M. and Murray, E.A. (2002). Perirhinal cortex resolves feature ambiguity in complex visual discriminations. European Journal of Neuroscience 15: 365-74
Bussey, T.J., Saksida, L.M. & Rothblat, L.A. (2001). Discrimination of computer-graphic stimuli by mice: A method for the behavioral characterization of transgenic and gene-knockout models. Behavioral Neuroscience, 115: 957-960
Murray, E.A. & Bussey, T.J. (1999). Perceptual-mnemonic functions of perirhinal cortex. Trends in Cognitive Sciences, 3: 142-151 (invited article). For Commentary on this paper, see Simons et al. (2003) Trends in Cognitive Sciences, 3:248-249
Bussey, T.J., Muir, J.L. & Aggleton, J.P. (1999). Functionally dissociating aspects of event memory: The effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat. Journal of Neuroscience, 19: 495-502. Demonstrated dissociations between object recognition and place learning, and provided evidence of differential hippocampal and perirhinal cortex function
Bussey, T.J., Warburton, E.C., Aggleton, J.P. & Muir, J.L. (1998). Fornix lesions can facilitate acquisition of the transverse patterning task: A challenge for “configural” theories of hippocampal function. Journal of Neuroscience, 18: 1622-1631
Bussey, T.J., Muir, J.L., Everitt, B.J. & Robbins, T.W. (1997). Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat. Behavioral Neuroscience, 111: 920-936
Bussey, T.J., Muir, J.L. & Robbins, T.W. (1994). A novel automated touchscreen procedure for assessing learning in the rat using computer graphic stimuli. Neuroscience Research Communications, 15: 103-110

Funding

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Blaine Chronik

Blaine Chronik

Contact information

Tel: (519) 661-2111 x86455
Email: bchronik@uwo.ca
Website: Chronik Group

Department

Physics & Astronomy

Research Areas

  • Developing new hardware systems and techniques for magnetic resonance imaging (MRI)

Publications

J. L. Chin, M. Billia, J. Relle, M. C. Roethke, I. V. Popeneciu, T. H. Kuru, G. Hatiboglu, M. B. Mueller-Wolf, J. Motsch, C. Romagnoli, Z. Kassam, C. C. Harle, J. Hafron, K. R. Nandalur, B. A. Chronik, M. Burtnyk, H-P Schlemmer, S. Pahernik. Magnetic Resonance Imaging-Guided Transurethral Ultrasound Ablation of Prostate Tissue in Patients with Localized Prostate Cancer: A Prospective Phase 1 Clinical Trial. European Urology (2016).
K. El Bannan, B.A. Chronik, S.P. Salisbury. Development of an MRI-compatible, compact, rotary-linear piezoworm actuator. Journal of Medical Devices 9(1):014501.1-7 (2015). [DOI: 10.1115/1.4028943]
K.C. Goodrich, J.R. Hadley, S. Kim, J.D. Kaggie, W.B. Handler, B.A. Chronik, B.D. Bolster, D.L. Parker. Peripheral nerve stimulation measures in a composite gradient system. Concepts in Magnetic Resonance Part B 44B(3):66-74 (2015). [DOI: 10.1002/cmr.b.21269]
S. Caterine, R. Litchfield, M. Johnson, B. Chronik, A. Getgood. A cadaveric study of the anterolateral ligament: re-introducing the lateral capsular ligament. Knee Surg Sports Traumatol Arthrosc. [Epub ahead of print], Jun 15 (2014). [PMID: 24929656]
Y. Zhao, T. Zhao, S.B. Raval, N. Krishnamurthy, H. Zheng, C.T. Harris, W.B. Handler, B.A. Chronik, T.S. Ibrahim. Dual optimization method of radiofrequency and quasistatic field simulations for reduction of eddy currents generated on 7T radiofrequency coil shielding. Magn Reson Med 74(5):11461-1469 (2015). [DOI: 10.1002/mrm.25424]
J. Cepek, B.A. Chronik, A. Fenster. The effects of magnetic field distortion on the accuracy of passive device localization frames in MR imaging. Med Phys 41(5):052301 (2014). [DOI: 10.1118/1.4870961][PMID: 24784394]
J. Cepek, B.A. Chronik, A. Fenster. Errors in device localization in MRI using Z-frames. Med Image Comput Comput Assist Interv, 16(Pt 1):348-55 (2013). [PMID: 24505685]
C.T. Harris, W.B. Handler, Y. Araya, F. Martinez-Santiesteban, J.K. Alford, B. Dalrymple, F. Van Saas, B.A. Chronik, T.J. Scholl. Development and optimization of hardware for delta relaxation enhanced magnetic resonance imaging. Magnetic Resonance in Medicine, 72(4):1182-1190 (2014). [DOI: 10.1002/mrm.25014][PMID: 24407990].
C.T. Harris, D.W. Haw, W.B. Handler, B.A. Chronik. Shielded electromagnets of arbitrary surface geometry using the boundary element method and a minimum energy constraint. Journal of Magnetic Resonance, 234:95-100 (2013). [DOI: 10.1016/j.jmr.2013.06.010] [PMID: 23851026]
C.T. Harris, D.W. Haw, W.B. Handler, B.A. Chronik. Application and experimental validation of an integral method for the simulation of gradient-induced eddy currents on arbitrary conducting surfaces. Physics in Medicine and Biology, 58(12):4367-4379 (2013). [DOI: 10.1088/0031-9155/58/12/4367] [PMID: 23739174]

Funding

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Adam Cohen

Adam Cohen

Contact information

Tel: (519) 661-2111 x84596
Email: acohen42@uwo.ca
Website: Social Brain Lab

Department

Psychology

Research Areas

  • How theory of mind and attention work, develop, and interface using behavioral and neuroimaging methods

Publications

Cohen, A. S., Sasaki, J. Y., German, T. C., & Kim, H. S. (in press). Automatic mechanisms for social attention are culturally penetrable. Cognitive Science.
Cohen, A. S., Sasaki, J. Y., & German, T. C. (2015). Specialized mechanisms for theory of mind: Are mental representations special because they are mental or because they are representations? Cognition, 136, 49-63.
German, T.C. & Cohen, A.S. (2012). A cue-based approach to ‘theory of mind’: Re-examining the notion of automaticity. British Journal of Developmental Psychology, 30, 45-58.
Cohen, A.S. & German, T.C. (2010). Reaction time advantages for calculating beliefs over public representations signal domain specificity for ‘theory of mind’. Cognition, 115, 417-425.
Cohen, A.S. & German, T.C. (2009). Encoding of others' beliefs without overt instruction. Cognition, 111, 356-363.

Funding

  • Western Strategic Support NSERC Grant
  • Social Science Research Fund Grant

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Brian Corneil

Brian Corneil

Contact information

Tel: (519) 663-5777 x24132
Email: bcorneil@uwo.ca
Website: Gaze Control Lab

Department

Physiology & Pharmacology, Psychology

Research Areas

  • Neurophysiological and behavioural studies of the neural control of movement

Publications

Gu, C., Wood, D.K., Gribble, P.L., Corneil, B.D. (2016) A trial-by-trial window into sensorimotor transformations in the human motor periphery. Accepted at J Neurosci
Lehmann, S.J. and Corneil, B.D. (2016) Transient pupil dilation after sub-saccadic microstimulation of primate Frontal Eye Fields. J Neurosci 36: 3765-3776.
Goonetilleke, S.C., Katz, L., Wood, D.K., Gu, C., Huk, A.C., Corneil, B.D. (2015) Cross-species comparison of anticipatory and stimulus-driven neck muscle activity well before saccadic gaze shifts in humans and non-human primates. J Neurophys 114: 902-913.
Gu, C. and Corneil, B.D. (2014) TMS of the prefrontal cortex in awake non-human primates evokes a polysynaptic neck muscle response that reflects oculomotor activity at the time of stimulation. J Neurosci 34: 14803-14815.
Corneil, B.D. and Munoz, D.P. (2014) Overt responses during covert orienting. Neuron 82: 1230-1243.
Chapman, B.B. and Corneil, B.D. (2014) Short-duration stimulation of the supplementary eye fields perturbs anti-saccades while potentiating contralateral head orienting. Eur J Neurosci 39: 295-307.
Peel, T.R., Johnston, K, Lomber, S.G., Corneil, B.D. (2014) Bilateral saccadic deficits following large and reversible inactivation of unilateral frontal eye field. J Neurophysiol 111: 415-433.
Corneil, B.D., Chen, J.C., Goonetilleke, S.C. (2013) Dynamic and opposing adjustment of movement cancellation and generation in an oculomotor countermanding task. J Neurosci 33: 9975-9984.
Buchholz, V.N., Goonetilleke, S.C., Medendorp, W.P., Corneil, B.D. (2012) Greater benefits of multisensory integration during complex sensorimotor transformations. J Neurophysiol 107: 3135-3143.
Goonetilleke, S.C., Gribble, P.L., Mirsattari, S.M., Doherty, T.J., Corneil, B.D. (2011) Neck muscle responses evoked by transcranial magnetic stimulation of the human frontal eye fields. Eur J Neurosci 33: 2155-2167.
Corneil, B.D., Elsley, J.K., Nagy, B., Cushing, S.L. (2010) Motor output evoked by sub-saccadic stimulation of primate frontal eye fields Proc Natl Acad Sci 107: 6070-6075.

Funding

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Jody Culham

Jody Culham

Contact information

Tel: (519) 661-3979
Email: jculham@uwo.ca
Website: Culham Lab

Department

Psychology

Research Areas

  • Neuroimaging of human brain regions involved in vision and hand actions

Publications

Gerhard, T. M., Culham, J. C. & Schwarzer, G. (In press). Distinct visual processing of real objects and pictures of those objects in 7- to 9-month-old infants. Frontiers in Developmental Psychology
Squires, S. D., Macdonald, S. N., Culham, J. C., & Snow, J. C. (2016). Priming tool actions: Are real objects more effective primes than pictures? Experimental Brain Research, 234(4), 963-976.
Thaler, L., Paciocco, J. Daley, M., Lesniak, G. D., Purcell, D. W., Fraser, J. A., Dutton, G. N., Rossit, S., Goodale, M. A., & Culham, J. C. (2016). A selective impairment of perception of sound motion direction in peripheral space: A case study. Neuropsychologia, 80, 79-89.
Stöttinger, E., Filipowicz, A., Valadao, D., Culham, J., Goodale, M., Anderson, B., & Danckert, J. (2016). A cortical network that marks the moment when conscious representations are updated. Neuropsychologia, 79, 113-122.
Quinlan, D. J., & Culham, J. C. (2015). Direct comparisons of hand and mouth kinematics during grasping, feeding and fork-feeding actions. Frontiers in Human Neuroscience, 9: 580.
Snow, J. C., Goodale, M. A., & Culham, J. C. (2015). Preserved haptic shape processing after bilateral LOC lesions. Journal of Neuroscience, 35(40), 13745-13760.
Macdonald, S. N. & Culham, J. C. (2015). Do human brain areas involved in visuomotor actions show a preference for real tools over visually similar non-tools? Neuropsychologia, 77, 35-41.
Barnett-Cowan, M., Snow, J. C., & Culham, J. C. (2015). Contribution of bodily and gravitational orientation cues to face and letter recognition. Multisensory Research, 28(5-6), 427-442.
Hutchison, R. M., Culham, J. C., Flanagan, J. R., Everling, S., & Gallivan, J. P. (2015). Functional subdivisions of medial parieto-occipital cortex in humans and nonhuman primates using resting-state fMRI. NeuroImage, 116, 10-29.
Gallivan, J. P., & Culham, J. C. (2015). Neural coding within human brain areas involved in actions. Current Opinion in Neurobiology, 33, 141-149.

Funding

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Rhodri Cusack

Rhodri Cusack

Contact information

Tel: (519) 661-2111 x86381
Email: rcusack@uwo.ca
Website: Cusack Lab

Department

Psychology, Medical Biophysics

Research Areas

  • The emergence of cognition in the first 1000 days
  • Neuroimaging methods for newborns and infants
  • The effects of perinatal brain injury

Publications

Cusack, R., Ball, G., Smyser, C.D., Dehaene-Lambertz, G. (in press). A Neural Window on the Emergence of Cognition, Annals of the New York Academy of Sciences.
Taylor, J.R., Williams, N., Cusack, R., Auer, T., Shafto, M.A., Dixon, M., Tyler, L.K., Cam-CAN, Henson, R.N.A. (in press). The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) data repository: Structural and functional MRI, MEG, and cognitive data from a cross-sectional adult lifespan sample, Neuroimage.
Erez, J., Cusack, R., Kendall, W., Barense, M.D. (2016). Conjunctive coding of complex object features in human anterior temporal cortex, Cerebral Cortex 26(5) 2271-82.
Tsvetanov, K. A., Henson, R. N. A., Tyler, L. K., Razi, A., Geerligs, L., Ham, T. E., Cam-CAN & Rowe, J. B. (2016). Extrinsic and Intrinsic Brain Network Connectivity Maintains Cognition across the Lifespan Despite Accelerated Decay of Regional Brain Activation. Journal of Neuroscience, 36(11) 3115–3126. doi:10.1523/JNEUROSCI.2733-15.2016.
Mitchell, D.J. & Cusack, R. (2016). Semantic and Emotional Content of Imagined Representations in Human Occipitotemporal Cortex. Scientific Reports 6:20232. DOI: 10.1038/srep20232.
Phillips, H. N., Blenkmann, A., Hughes, L. E., Kochen, S., Bekinschtein, T. A., Cam-CAN, & Rowe, J. B. (2016). Convergent evidence for hierarchical prediction networks from human electrocorticography and magnetoencephalography. Cortex. doi:10.1016/j.cortex.2016.05.001
Geerligs, L., Cam-CAN, & Henson, R. N. (2016). Functional connectivity and structural covariance between regions of interest can be measured more accurately using multivariate distance correlation. NeuroImage, 135, 16–31. doi:10.1016/j.neuroimage.2016.04.047
Green, E., Shafto, M.A., Matthews, F.E., Cam-CAN, White, S.R. (2015). Adult Lifespan Cognitive Variability in the Cross-Sectional Cam-CAN Cohort, International Journal of Environmental Research and Public Health, 12(12) 15516-30.
Ray, L., Sockeel, S., Soon, M., Bore. A., Myhr, A., Cusack, R., Owen, A.M., Carrier, J., Doyon, J., Fogel, S.M (2015). Expert and crowd-sourced validation of an individualized sleep spindle detection method employing complex demodulation and individualized normalization, Frontiers in Human Neuroscience, DOI: 10.3389/fnhum.2015.00507
Campbell, K., Shafto, M., Wright, P., Tsvetanov, K., Cusack, R., Cam-CAN Research Team, Tyler, L.K. (2015). Idiosyncratic responding during movie-watching predicted by age differences in attentional control, Neurobiology of Aging, 36(11) 3045–55.

Funding

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Mark Daley

Mark Daley

Contact information

Tel: (519) 661-2111 x87897
Email: mdaley2@uwo.ca
Website: Daley Lab

Department

Computer Science, Biology

Research Areas

  • Natural Computing
  • Theoretical Computer Science
  • Mathematical Modelling of Biological Systems
  • Computational Neuroscience & Neuroinformatics

Publications

J. A. Sobotka, M. Daley, S. Chandrasekaran, B. D. Rubin, and G. J. Thompson, \Structure and function of gene regulatory networks associated with worker sterility in honeybees," Ecology and Evolution, n/a{n/a, 2016, issn:2045-7758. doi: 10.1002/ece3.1997. [Online]. Available: http://dx.doi.org/10.1002/ece3.1997.
A. Tammour, S. C. Gallagher, M. Daley, and G. T. Richards, \Insights into quasar uv spectra using unsupervised clustering analysis," Monthly Notices of the Royal Astronomical Society, 2016. doi: 10.1093/mnras/stw586. eprint: http://mnras.oxfordjournals.org/content/early/2016/03/11/mnras.stw586.full.pdf+html. [Online]. Available: http://mnras.oxfordjournals.org/content/early/2016/03/11/mnras.stw586.abstract.
L. Thaler, J. Paciocco, M. Daley, G. D. Lesniak, D. W. Purcell, J. A. Fraser, G. N. Dutton, S. Rossit, M. A. Goodale, and J. C. Culham, \A selective impairment of perception of sound motion direction in peripheral space: a case study," Neuropsychologia, vol. 80, pp. 79{89, Jan. 2016. doi: http://dx.doi.org/10.1016/j.neuropsychologia.2015.11.008. [Online]. Available: http://www.sciencedirect.com/science/article/pii/S0028393215302232.
J. Butler, F. Mackay, C. Denniston, and M. Daley, \Halting the hallmarks: a cellular automaton model of early cancer growth inhibition," pp. 1{16, 2015. doi: 10.1007/s11047-015-9508-3. [Online]. Available: http://dx.doi.org/10.1007/s11047-015-9508-3.
M Locke, M. Milojevic, S. Eitutis, N. Patel, A. Wishart, M. Daley, and K. Hill, \Genomic copy number variation in mus musculus," BMC Genomics, vol. 16, no. 1, p. 497, 2015. [Online]. Available: http://www.biomedcentral.com/1471-2164/16/497.
M. Daley, \An invitation to the study of brain networks with some statistical analysis of thresholding techniques," in Discrete and Topological Models in Molecular Biology, N. Jonoska and M. Saito, Eds. Springer Berlin Heidelberg, 2014, pp. 85{107.
The complexity of genomic structural variation in neurodevelopmental disorders," Biological psychiatry, vol. 75, no. 5, pp. 344{345, Mar. 2014. [Online]. Available: http://linkinghub.elsevier.com/retrieve/pii/S0006322313010950?showall=true.
E. Mullen, M. Daley, A. Backx, and G. Thompson, \Gene co-citation networks associated with worker sterility in honey bees," BMC Systems Biology, vol. 8, no. 1, p. 38, 2014. [Online]. Available: http://www.biomedcentral.com/1752-0509/8/38.
J. L. Butler, M. E. Osborne Locke, K. A. Hill, and M. Daley, \Hd-cnv:hotspot detector for copy number variants.," eng, Bioinformatics, vol. 29, no.2, pp. 262{263, 2013, issn: 1367-4811 (Electronic); 1367-4803 (Linking). doi:10.1093/bioinformatics/bts650.
F. Biegler, M. Daley, and I. McQuillan, \Algorithmic decomposition of shuffle on words," Theor. Comput. Sci., vol. 454, pp. 38{50, 2012.

Funding

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Jörn Diedrichsen

jorn diedrichsen

Contact information

Tel: (519) 661-2111 x86994
Email: jdiedric@uwo.ca 
Website: Motor Control Group

Department

Computer Science, Statistics

Research Areas

  • Computational Neuroscience
  • Motor Control and Learning
  • Neuroimaging

Publications

Diedrichsen, J., & Kornysheva, K. (2015). Motor skill learning between selection and execution. Trends Cogn Sci, 19(4), 227-233.
Ejaz, N., Hamada, M., & Diedrichsen, J. (2015). Hand use predicts the structure of representations in sensorimotor cortex. Nat Neurosci, 18(7), 1034-1040.
Galea, J. M., Mallia, E., Rothwell, J., & Diedrichsen, J. (2015). The dissociable effects of punishment and reward on motor learning. Nat Neurosci, 18(4), 597-602.
Telgen, S., Parvin, D., & Diedrichsen, J. (2014). Recalibrating or learning de novo? Mirror reversal and visual rotation are learned and consolidated via separate mechanisms. Journal of Neuroscience.
Kornysheva, K., & Diedrichsen, J. (2014). Spatial and temporal features of motor sequences are stored independently in human premotor areas. eLife
Wiestler, T., Waters-Metenier, S., & Diedrichsen, J. (2014). Effector-independent motor sequence representations exist in extrinsic and intrinsic reference frames. Journal of Neuroscience.
Reichenbach, A., Franklin, D. W., Zatka-Haas, P., & Diedrichsen, J. (2014). A dedicated binding mechanism for the visual control of movement. Current Biology.
Waters-Metenier, S., Husain, M., Wiestler, T., & Diedrichsen, J. (2014) Bihemispheric tDCS enhances effector-independent representations of motor synergy and sequence learning. Journal of Neuroscience.
Wiestler, T., & Diedrichsen, J. (2013). Skill learning strengthens cortical representations of motor sequences. eLife.
Diedrichsen, J., Wiestler, T., & Ejaz, N. (2013). A multivariate method to determine the dimensionality of neural representation from population activity. Neuroimage.
Diedrichsen, J., Wiestler, T., & Krakauer, J. W. (2012). Two distinct ipsilateral cortical representations for individuated finger movements. Cerebral Cortex.
Schlerf, J., Ivry, R. B., & Diedrichsen, J. (2012). Encoding of sensory prediction errors in the human cerebellum. Journal of Neuroscience, 32(14), 4913-4922.
Wolpert, D. M., Diedrichsen, J., & Flanagan, J. R. (2011). Principles of sensorimotor learning. Nat Rev Neurosci, 12(12), 739-751.
Wiestler, T., McGonigle, D. J., & Diedrichsen, J. (2011). Integration of sensory and motor representations of single fingers in the human cerebellum. J Neurophysiol.

Funding

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Stefan Everling

Stefan Everling

Contact information

Tel: (519) 663-5777 x24359
Email: severlin@uwo.ca
Website: Laboratory for Neural Circuits & Cognitive Control

Department

Physiology & Pharmacology, Psychiatry, Psychology

Research Areas

  • Organization of the primate prefrontal cortex
  • Saccadic eye movements

Publications

Hutchison RM, Gallivan JP, Culham JC, Gati JS, Menon RS, Everling S (2012).  Functional connectivity of the frontal eye fields in humans and macaques investigated with resting-state fMRIJ Neurophysiol., 107: 2463-2474.
Hutchison RM, Womelsdorf T, Gati JS, Everling S, Menon RS (2012). Resting-state networks show dynamic functional connectivity in awake humans and anesthetized macaques. Human Brain Mapping doi: 10.1002/hbm.22058.
Kaping D, Vinck M, Hutchison RM, Everling S, Womelsdorf T (2011). Specific contributions of ventromedial, anterior cingulate, and lateral prefrontal cortex for attentional selection and stimulus valuationPLoS Biol, 9(12): e1001224. doi:10.1371/journal.pbio.1001224.
Hutchison RM, Womelsdorf T, Gati JS, Leung LS, Menon RS, Everling S (2011).  Resting-state connectivity identifies distinct functional networks in macaque cingulate cortex.Cerebral Cortex.
Koval MJ, Lomber SG, Everling S (2011). Prefrontal cortex deactivation in macaques alters activity in the superior colliculus and impairs voluntary control of saccades. J. Neurosci., 31: 8659-8668.
Hutchison RM, Leung LS, Mirsattaril SM, Gati JS, Menon RS, Everling S (2011). Resting-state networks in the macaque at 7 TNeuroimage, 56: 1546-1555.
Phillips, J.M., Johnston, K., & Everling, S. (2011). Effects of anterior cingulate microstimulation on pro- and anti-saccades in nonhuman primates. Journal of Cognitive Neuroscience, 23: 481-490.
Womelsdorf, T., Johnston, K., Vinck, M., & Everling, S. (2010). Theta-Activity in anterior cingulate cortex predicts task rules and their adjustments following errors. Proceedings of the National Academy of Sciences (USA), 107, 5248-5253.
Sander, V., Soper, B., & Everling, S. (2010). Nonhuman primate event-related potentials associated with pro- and anti-saccades. NeuroImage, 49, 1650-1658.

Funding

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Melvyn Goodale

Melvyn Goodale

Contact information

Tel: (519) 661-2070
Email: mgoodale@uwo.ca
Website: Goodale Lab

Department

Physiology & Pharmacology, Psychology

Research Areas

  • Visual perception and visually guided actions, using behavioral studies, fMRI, and neuropsychology

Publications

Whitwell, R.L., Buckingham, G., Enns, J.T., Chouinard, P.A., & Goodale M.A. (in press) Rapid decrement in the effects of the Ponzo display dissociates action and perception. Psychonomic Bulletin and Review.
Paulun, V.C., Gegenfurtner, K.R., Goodale, M.A., & Fleming, R.W. (in press). Effects of material properties and object orientation on precision grip kinematics. Experimental Brain Research.
Buckingham, G., Goodale, M.A., White, J.A., Westwood, D.A. (2016). Equal-magnitude size-weight illusions experienced within and between object categories. Journal of Vision, 16(3):25.
Tang, R., Whitwell, R.L., & Goodale, M.A. (2016). Unusual hand postures but not familiar tools show motor equivalence with precision grasping. Cognition, 151, 28-36.
Crewther, D. P., Crewther, D., Bevan, S., Goodale, M. A., & Crewther, S. G. (2015). Greater magnocellular saccadic suppression in high versus low autistic tendency suggests a causal path to local perceptual style. Royal Society Open Science, 2, 150226.
Thaler, L., Paciocco, J., Daley, M., Lesniak, G.D., Purcell, D.W., Fraser, J.A., Dutton, G.N., Rossit, S., Goodale, M.A., & Culham, J.C. (2016). A selective impairment of perception of sound motion direction in peripheral space: A case study. Neuropsychologia, 80, 79-89.
Stöttinger, E., Filipowicz, A., Valadao, D., Culham, J.C., Goodale, M.A., Anderson, B., & Danckert, J. (2015). A cortical network that marks the moment when conscious representations are updated. Neuropsychologia, 79, 113-122.
Snow, J.C., Goodale, M.A., & Culham, J.C. (2015). Preserved haptic shape processing after bilateral LOC lesions. Journal of Neuroscience, 35, 13745-13760.
Carey, D.P., Otto-de Haart, E.G., Buckingham, G., Dijkerman, H.C., Hargreaves, E.L., & Goodale, M.A. (2015). Are there right hemisphere contributions to visually-guided movement? Manipulating left hand reaction time advantages in dextrals. Frontiers in Psychology,6:1203.
Wood, D.K., Gu, C., Corneil, B.D., Gribble, P.L., & Goodale, M.A. (2015). Transient visual responses reset the phase of low-frequency oscillations in the skeletomotor periphery. European Journal of Neuroscience, 42, 1919-1932.

Funding

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Jessica Grahn

jessica grahn

Contact information

Tel: (519) 661-2111 x84804
Email: jgrahn@uwo.ca
Website: Music and Neuroscience Lab

Department

Psychology

Research Areas

  • Neuroscience of music

Publications

D.J. Cameron*, K.A. Pickett, G.M. Earhart, J.A. Grahn, The effect of dopaminergic medication on beat-based auditory timing in Parkinson’s disease. (2016) Frontiers in Neurology, 7:19 doi: 10.3389/fneur.2016.00019
A. Corbett, A.M. Owen, A. Hampshire, J.A. Grahn, R. Stenton, S. Dajani, A. Burns, R. Howard, N. Williams, C. Ballard, The effect of an online training package on cognition in healthy adults over 50: an online randomised controlled trial. (2015) JAMDA Journal of the American Medical Directors Association,16(11) 990-7. doi:10.1016/j.jamda.2015.06.014
J.D. Holmes, L.K. Brigham, M.E. Jenkins, E.A. Ready*, S.G. Lutz, A.M. Johnson, J.A. Grahn, The effects of manipulating spatial location of visual cue placement on gait among individuals with Parkinson's Disease: A pilot study. (2015) Physical and Occupational Therapy in Geriatrics, 33: 263-278. doi: 10.3109/02703181.2015.1045109
D.J. Cameron*, J.A. Grahn, Cross-Cultural Influences on Rhythm Processing: Reproduction, Discrimination, and Beat Tapping. (2015), Frontiers in Auditory Cognitive Neuroscience, 6:366. doi: 10.3389/fpsyg.2015.00366
H. Merchant, J.A. Grahn, L.J. Trainor, M. Rohrmeier, W.T. Fitch. Finding the beat: a neural perspective across human and non-human primates. (2015) Philosophical Transactions of the Royal Society B, 370: 20140093 doi: 10.1098/rstb.2014.0093
S. Reaves, B. Graham, J. A. Grahn, P. Rabannifard, A. Duarte, Turn off the music! Music impairs visual associative memory performance in older adults (2015) The Gerontologist, doi: 10.1093/geront/gnu113
L.-A. Leow*, V.-R. Rinchon*, J.A. Grahn. Familiar music increases walking speed in rhythmic auditory cueing. (2015) Annals of the New York Academy of Sciences, 1337:53-61 doi: 10.1111/nyas.12658
D.J. Cameron*, J.A. Grahn. Enhanced temporal production abilities in percussionists generalize beyond entrainment and musical plausibility. (2014) Frontiers in Human Neuroscience, 8:1003. doi: 10.3389/fnhum.2014.01003
L.-A. Leow*, T. Parrott*, J. A. Grahn. Individual differences in beat perception affect gait responses to low- and high-groove music. (2014) Frontiers in Human Neuroscience, 8:811. doi: 10.3389/fnhum.2014.00811
D.J. Cameron*, J.A. Grahn. Neuroscientific investigations of musical rhythm. (2014) Acoustics Australia, 42(2), 111 - 116

Funding

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Paul Gribble

Paul Gribble

Contact information

Tel: (519) 661-2111 x82237
Email: paul@gribblelab.org
Website: Human Sensory Motor Neuroplasticity and Motor Learning

Department

Physiology & Pharmacology, Psychology

Research Areas

  • How the brain controls voluntary movement, and how movement is learned

Publications

McGregor HR, Cashaback JG, Gribble PL. (2016) Functional Plasticity in Somatosensory Cortex Supports Motor Learning by Observing. Current Biology 26(7):921-927
Wong JD, Bobbert MF, van Soest KAJ, Gribble PL, Kistemaker DA (2016) Optimizing the distribution of leg muscles for vertical jumping. PLoS ONE 11(2):e0150019, 2016
Ostry DJ, Gribble PL (2016) Sensory plasticity in human motor learning. Trends In Neurosciences 39(2):114-123
Martin CB, Cowell RA, Gribble PL, Wright J, Köhler S (2015) Distributed category-specific recognition memory signals in human perirhinal cortex. Hippocampus 26:423-436
Weiler J, Gribble PL, Pruszynski JA (2015) Goal-dependent modulation of the long-latency stretch response at the shoulder, elbow and wrist. J. Neurophysiol. 114(6):3242-54
Wood DK, Gu C, Corneil BD, Gribble PL, Goodale MA (2015) Transient visual responses reset the phase of low-frequency oscillations in the skeletomotor periphery. Eur. J. Neurosci. 42:1919-32
McGregor HR, Gribble PL (2015) Changes in Visual and Sensory-Motor Resting-State Functional Connectivity Support Motor Learning by Observing. J. Neurophysiol. 114:677-88
Cashaback JGA, McGregor HR, Gribble PL (2015) The Human Motor System Alters Its Reaching Movement Plan for Task-Irrelevant Positional Forces. J. Neurophysiol. 113:2137-49
Kistemaker DA, Wong J, Gribble PL (2014) The cost of moving optimally: kinematic path selection. J. Neurophysiol. 112, 1815-24
Buckingham G, Wong JD, Tang M, Gribble PL, Goodale MA (2014) Observing object lifting errors modulates cortico-spinal excitability and improves object lifting performance. Cortex 50, 115-24

Funding

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Elizabeth Hayden

Elizabeth Hayden

Contact information

Tel: (519) 661-2111 x83686
Email: ehayden@uwo.ca
Website: Personality and Emotion Development Lab

Department

Psychiatry, Psychology

Research Areas

  • Developmental psychopathology of mood disorders
  • Assessment of temperament and personality

Publications

Johnson, V.C., Olino, T.M., Klein, D.N. & Hayden, E.P. (in press). A longitudinal investigation of predictors of the stability of behavioural inhibition in early childhood. Journal of Research in Personality.
Mackrell, S.V.M., Kotelnikova, Y., Jordan, P.L., & Hayden, E.P. (in press). The role of pubertal development in emerging depression risk in middle childhood. Personality and Individual Differences.
Kotelnikova, Y., Olino, T.M., Klein, D.N., Mackrell, S.V.M., & Hayden, E.P. (in press). Higher- and lower-order factor analyses of the Temperament in Middle Childhood Questionnaire (TMCQ). Assessment
Johnson, V.C., Kryski, K.R., Sheikh, H.I., Smith, H.J., Singh, S.M., & Hayden, E.P. (in press). The serotonin transporter promoter polymorphism moderates the continuity of behavioural inhibition in early childhood. Development and Psychopathology.
Kotelnikova, Y., Olino, T.M., Klein, D.N., Mackrell, S.V.M., & Hayden, E.P. (2015). Higher- and lower-order factor analyses of the Temperament in Middle Childhood Questionnaire. Psychological Assessment. Advance online publication.
Pagliaccio, D., Luking, K.R., Anokhin, A.P., Gotlib, I.H., Hayden, E.P., Olino, T.M., Peng, C., Proudfit, G.H., Barch, D.M. (2015). Revising the BIS/BAS to study development: Metric invariance and normative effects of age and sex from childhood through adulthood. Psychological Assessment. Advance online publication.
Kotelnikova, Y., Olino, T.M., Klein, D.N., Kryski, K.R., & Hayden, E.P. (2015). Higher- and lower-order factor analyses of the Children’s Behavior Questionnaire in early and middle childhood. Psychological Assessment. Advance online publication.
Harkness, K.L., Hayden, E.P., & Lopez-Duran, N.L. (2015). Stress sensitivity and stress sensitization in psychopathology: An introduction to the special section. Journal of Abnormal Psychology, 124, 1-3.
Ouellette, S.J., Russell, E., Kryski, K.R., Sheikh, H.I., Singh, S.M., Koren, G., & Hayden, E.P. (2015). Hair cortisol concentrations in higher- and lower-stress mother-daughter dyads: A pilot study of associations and moderators. Developmental Psychobiology, 57, 519-534.
Goldstein, B.L., Hayden, E.P., & Klein, D.N. (2014). Stability of self-referent encoding task performance and associations with change in depressive symptoms from early to middle childhood. Cognition and Emotion, 22, 1-11.

Funding

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Marc Joanisse

Marc Joanisse

Contact information

Tel: (519) 661-2111 x86582
Email: marcj@uwo.ca
Website: LRCN Lab

Department

Psychology

Research Areas

  • How the brain supports first- and second-language learning
  • Developmental language and reading impairments
  • Dyslexia

Publications

Joanisse, M.F. & McClelland, J.L. (2015). Connectionist perspectives on language learning, representation and processing.WIREs Cognitive Science. doi: 10.1002/wcs.1340
Welcome, S.E., Pasquarella, A., Chen, X., Olson, D.R. & Joanisse, M.F. (2014). Preserved Mid-Fusiform Activation for Visual Words in a Patient with a Visual Word Recognition Impairment. Neuropsychologia. 65: 113:124. doi:10.1016/j.neuropsychologia.2014.10.012
Malins, J.G., Gao, D., Tao, R., Booth, J., Shu, H., Joanisse, M.F., Liu, L. & Desroches, A.S. (2014). Developmental differences in the influence of phonological similarity on spoken word processing in Mandarin Chinese. Brain and Language Brain and Language. 138: 38-50. Doi 10.1016/j.bandl.2014.09.002
Joanisse, M.F. & Desouza, D.D. (2014) Sensitivity of human auditory cortex to rapid frequency modulation revealed by multivariate representational similarity analysis. Frontiers in Neuroscience. 8:306. doi: 10.3389/fnins.2014.00306
Welcome, S.E. & Joanisse, M.F. (2014). Individual differences in white matter anatomy predict dissociable components of reading skill in adults. NeuroImage, 96, 261-75. doi: 10.1016/j.neuroimage.2014.03.069
Sheikh, H, Joanisse, M.F., Mackrell, S., Kryski, K., Smith, H., Singh, S. & Hayden, E. (2014). Links between white matter microstructure and cortisol reactivity to stress in early childhood: Evidence for moderation by parenting. NeuroImage: Clinical. 6, 77-85. DOI: 10.1016/j.nicl.2014.08.013
Andrew, K., Hoshooley, J. & Joanisse, M.F. (2014) Sign language ability in young deaf signers predicts comprehension of written sentences in English. PLoS One 9(2): e89994. doi: 10.1371/journal.pone.0089994
McNorgan, C. Joanisse, M.F. (2014). A connectionist approach to mapping the human connectome permits simulations of neural activity within an artificial brain Brain Connectivity 4: (1), 40-52. doi:10.1089/brain.2013.0174
Archibald, L.M.D., Oram Cardy, J., Joanisse, M.F. & Ansari, D. (2013). Language, Reading, and Math Learning Profiles in an Epidemiological Sample of School Age Children. PLoS One, 10:8. E77463.
Malins, J.G., Desroches, A.S., Robertson, E.K., Newman R.L., Archibald, L. & Joanisse, M.F. (2013). ERPs reveal the temporal dynamics of auditory word recognition in specific language impairment. Developmental Cognitive Neuroscience, 5, 138-148.

Funding

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Ingrid Johnsrude

Ingrid Johnsrude

Contact information

Tel: (519) 661-2111 x84447
Email: ijohnsru@uwo.ca
Website: CoNCH Lab

Department

Psychology

Research Areas

  • The neural basis of speech understanding
  • How people understand speech in challenging listening situations

Publications

Samson F., & Johnsrude IS. (2016) Effects of the constant presence of a target or masker voice on target speech intelligibility. Journal of the Acoustical Society of America, 139(3), 1037 PMID:27036241
Wayne, RV, Johnsrude IS. (2016). Working memory training and speech in noise comprehension in older adults. Frontiers in Aging Neuroscience, Mar 22, 8:49 PMID:27047370
Lee, S., Kilmade, M., Peltsch, A., Brien, D., Coe, B., Johnsrude, IS., Munoz, DP. (2016) Neural correlates of predictive saccades. Journal of Cognitive Neuroscience. PMID:27054397
Wayne RV, Johnsrude IS. (2015) A review of causal mechanisms underlying the link between age-related hearing loss and cognitive decline. Ageing Research Reviews 23:154-66.
Sikka R., Cuddy, L, Johnsrude IS, Vanstone, A. (2015). Neural activity associated with recognition of familiar melodies in younger and older adults: an fMRI study. Frontiers in Neuroscience. Oct 6; 9:356 PMID:26500480
Sutton, K, Pukall, CF, Wild C, Johnsrude I, Chamberlain, S. (2015) Cognitive, psychophysical, and neural correlates of vulvar pain in primary and secondary provoked vestibulodynia: A pilot study. Journal of Sexual Medicine, 12, 1283-1297.
Gallivan, J, Johnsrude, IS, Flanagan, JR. (2015). Planning ahead: Object-directed action sequences decoded from human frontoparietal and occipitotemporal networks. Cerebral Cortex, 26:708-30
Ramezani M, Abolmaesumi P, Marble K, Trang H, & Johnsrude IS. (2015). Fusion analysis of functional MRI data for classification of individuals based on patterns of activation. Brain Imaging and Behavior, 9, 149-161.
Zekveld AA, Heslenfeld DJ, Johnsrude IS, Versfeld NJ, & Kramer SE. (2014). The eye as a window to the listening brain: Neural correlates of pupil size as a measure of cognitive listening load. NeuroImage, 101, 76-86.
Ramezani, M, Abolmaesumi, P, Tahmasebi, A, Bosma, R, Tong, R, Hollenstein, T, Harkness, K & Johnsrude, IS. (2014). Fusion analysis of depression in first episode depression: Where brain shape deformations meet local composition of tissue. NeuroImage Clinical, 7, 114-121.

Funding

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Stefan Köhler

Stefan Kohler

Contact information

Tel: (519) 661-2111 x86299
Email: stefank@uwo.ca
Website: Köhler Memory Lab

Department

Psychology

Research Areas

  • The relationship between the cognitive and neural processes that allow humans to remember their past

Publications

Fiacconi, C.M., Peter, E. L., Owais, S. & Köhler, S. (2016). Knowing by heart: Visceral feedback shapes recognition memory judgments. Journal of Experimental Psychology: General, 145, 559-572
Epp, J.R., Mera, R.S., Köhler, S., Josselyn, S.A., Frankland, P.W. (2016). Neurogenesis-mediated forgetting minimizes proactive interference. Nature Communications, 7, 10838
Martin, C.B., Cowell, R.A., Gribble, P.L., Wright, J., Köhler, S. (2016). Distributed category-specific recognition memory signals in human perirhinal cortex. Hippocampus, 26, 423-436
Fiacconi, C. M., Dekraker, J., & Köhler, S. (2015). Psychophysiological evidence for the role of emotion in adaptive memory. Journal of Experimental Psychology: General, 144, 925-933.
Josselyn, S. A., Köhler, S., & Frankland, P. W. (2015). Finding the engram. Nature Reviews Neuroscience, 16, 521–534.
O'Neil E.B., Protzner A.B., McCormick C., McLean D.A., Poppenk J., Cate A.D., & Köhler S. (2012). Distinct patterns of functional and effective connectivity between perirhinal cortex and other cortical regions in recognition memory and perceptual discrimination.Cerebral Cortex, 22, 74-85.
Bowles, B., Harlow, A.M., Meeking, M.M., & Köhler, S. Discriminating famous from fictional names based on lifetime experience: Evidence in support of a signal detection model based on finite mixture distributions. Journal of Experimental Psychology: Learning, Memory and Cognition.
Bowles, B., O’Neil, E.B., Mirsattari, S.M., Poppenk, J., & Köhler S. (2011). Preserved hippocampal novelty responses following anterior temporal-lobe resection that impairs familiarity but spares recollection. Hippocampus, 21, 847-854.
Cate, A.D., Goodale, M.A., & Köhler, S. (2011). The role of apparent size in building- and object-specific regions of ventral visual cortex. Brain Research, 1388, 109-122.
O'Neil, E.B., Cate, A.D., & Köhler, S. (2009). Perirhinal Cortex Contributes to Accuracy in Recognition Memory and Perceptual Discriminations. Journal of Neuroscience, 29(26), 8329-8334.

Funding

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Stephen Lomber

Stephen Lomber

Contact information

Tel: (519) 661-2111 x24110
Email: steve.lomber@uwo.ca
Website: Cerebral Systems Lab

Department

Physiology & Pharmacology, Psychology

Research Areas

  • How does experience influence brain development?
  • Cortical processing in hearing and deaf individuals

Publications

Koval, M.J., Lomber, S.G. and Everling, S. (2011). Neuronal mechanisms for control of the superior colliculus by the prefrontal cortex. Journal of Neuroscience 31:8659-8668.
Meredith, M.A., Kryklywy, J., McMillan, A.J., Malhotra, S., Lum-Tai, R. and Lomber, S.G. (2011). Crossmodal reorganization in the early-deaf switches sensory, but not behavioral roles of auditory cortex. Proceedings of the National Academy of Sciences (USA) 108: 8856-8861.
Meredith, M.A. and Lomber, S.G. (2011). Somatosensory and visual crossmodal plasticity in the anterior auditory field of early-deaf cats. Hearing Research 280: 38-47.
Ponce, C., Hunter, N., Pack, C.C., Lomber, S.G. and Born, R.T. (2011).  Contributions of indirect pathways to visual response properties in macaque area MT. Journal of Neuroscience 31: 3894-3903.
Lomber, S.G., Meredith, M.A., and Kral, A. (2010). Crossmodal plasticity in specific auditory cortices underlies visual compensations in the deaf. Nature Neuroscience 13: 1421-1427.
Schmidt, K.E., Lomber, S.G., Payne, B.R., and Galuske, R.A. (2011). Pattern motion representation in primary visual cortex is mediated by transcortical feedback.NeuroImage 54: 474-484.
Lomber, S.G., Meredith, M.A., and Kral, A. (2010). Crossmodal plasticity in specific auditory cortices underlies visual compensations in the deaf.  Nature Neuroscience 13: 1421-1427.
Carrasco, A. and Lomber, S.G. (2010). Reciprocal modulatory influences between tonotopic and non-tonotopic cortical fields in the cat. Journal of Neuroscience 30: 1476-1487.

Funding

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Penny MacDonald

Penny MacDonald

Contact information

Tel: (519) 685-8500 x33631
Email: pmacdo7@uwo.ca
Website: MacDonald Lab

Department

Clinical Neurological Sciences

Research Areas

  • Understanding the neural bases for cognitive processes with particular interest in defining the unique role of the basal ganglia

Publications

Linton B, Fu R, MacDonald PA, Ganjavi H (In press). Burning pain secondary to clozapine use: a case report. BMC Psychiatry
Vo A, Hiebert NM, Seergobin KN, Solcz S, Partridge A, MacDonald PA, "Dopaminergic medication impairs learning but not decision making in Parkinson's disease", Frontiers in Neuroscience (in press)
Hiebert NM, Seergobin KN, Vo A, Ganjavi H, MacDonald PA, "Dopaminergic therapy affects learning and impulsivity in Parkinson's disease", Annals of Clinical and Translational Neurology (in press)
Ganjavi H, MacDonald PA, "On-off effect of dopaminergic therapy on psychiatric symptoms in Parkinson’s disease", Journal of Neuropsychiatry and Clinical Neuroscience (in press)
Hiebert NM, Vo A, Seergobin KN, Hampshire A, Owen AM, MacDonald PA, "Striatum in stimulus-response learning via feedback and decision making", Neuroimage, 101C:448-457
MacDonald AA, Seergobin KN, Tamjeedi R, Provost J-S, Monchi O, Ganjavi H, MacDonald PA (2014) "Dorsal striatum mediates cognitive flexibility not merely cognitive effort: Investigations in Parkinson’s Disease and using fMRI", Annals of Clinical and Translational Neurology, 1(6), 390-400
Burgaleta M, Macdonald PA, Martínez K, Román FJ, Alvarez-Linera J, González AR, Karama S, Colom R (2014) "Subcortical regional morphology correlates with fluid and spatial intelligence.", Human Brain Mapping, 35(5), 1957-68
Macdonald PA, Ganjavi H, Collins DL, Evans AC, Karama S (2014) "Investigating the relation between striatal volume and IQ.", Brain Imaging and Behavior, 8(1), 52-9
Macdonald AA, Seergobin KN, Owen AM, Tamjeedi R, Monchi O, Ganjavi H, Macdonald PA (2013) "Differential effects of Parkinson's disease and dopamine replacement on memory encoding and retrieval.", PLoS One, 8(9), e74044
MacDonald AA, Monchi O, Seergobin KN, Ganjavi H, Tamjeedi R, MacDonald PA (2013) "Parkinson's disease duration determines effect of dopaminergic therapy on ventral striatum function.", Movement Disorders, 28(2), 153-60
MacDonald PA, MacDonald AA, Seergobin KN, Tamjeedi R, Ganjavi H, Provost J-S, Monchi O (2011) "The effect of dopamine therapy on ventral and dorsal striatum-mediated cognition in Parkinson's disease: support from functional MRI.", Brain, 134(5), 1447-63
Macdonald PA, Monchi O (2011) "Differential effects of dopaminergic therapies on dorsal and ventral striatum in Parkinson's disease: implications for cognitive function.", Parkinson's Disease, (March 6), 572743
Ganjavi H, Lewis JD, Bellec P, MacDonald PA, Waber DP, Evans AC, Karama S (2011) "Negative associations between corpus callosum midsagittal area and IQ in a representative sample of healthy children and adolescents.", PLoS One, 6(5), e19698

Funding

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Julio Martinez-Trujillo

julio martinez

Contact information

Tel: (519) 931-5777 x24383
Email: julio.martinez@robarts.ca
Website: Cognitive Neurophysiology Laboratory

Department

Physiology & Pharmacology

Research Areas

  • Cognitive Neuroscience
  • Autism

Publications

Attentional filtering of visual information by neuronal ensembles in the primate lateral prefrontal cortex. Tremblay S, Pieper F, Sachs A, Martinez-Trujillo JC. Neuron. 2015 Jan 7;85(1):202-15
Sharp emergence of feature-selective sustained activity along the dorsal visual pathway. Mendoza-Halliday D, Torres S, Martinez-Trujillo JC. Nature Neuroscience. 2014 Sep;17(9):1255-62
Prefrontal neurons of opposite spatial preference display distinct target selection dynamics. Lennert T, Martinez-Trujillo JC. Journal of Neuroscience. 2013 May 29;33(22):9520-9

Funding

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Ken McRae

Ken McRae

Contact information

Tel: (519) 661-2111 x80449
Email:kenm@uwo.ca
Website: McRae Lab

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Ravi Menon

Ravi Menon

Contact information

Tel: (519) 661-2111 x24148
Email:rmenon@robarts.ca
Website: Menon Group

Department

Medical Biophysics, Medical Imaging, Physics & Astronomy, Psychiatry

Research Areas

  • Development and application of magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques

Publications

Connell, I.R.O. and Menon, R.S. General Coupling Matrix Synthesis for Decoupling MRI RF Arrays. IEEE Trans Med Imaging. [Epub ahead of print] (April 2016).
Streijger, F., Lee, J.H., Manouchehri, N., Okon, E.B., Tigchelaar, S., Anderson, L., Dekaban, G.A., Rudko, D., Menon, R.S., Iaci, J.F., Button, D.C., Vecchione, A.M., Konovalov, A., Sarmiere, P.D., Ung, C., Caggiano, A.O., Kwon, B.K. The Evaluation of Magnesium Chloride within a Polyethylene Glycol Formulation in a Porcine Model of Acute Spinal Cord Injury. J Neurotrauma. [Epub ahead of print] (April 2016).
Penner, J., Ford, K.A., Taylor, R., Schaefer, B., Théberge, J., Neufeld, R.W.J., Osuch, E.A., Menon. R.S., Rajakumar, N., Allman J.M., Williamson, P.C., Medial prefrontal and anterior insular connectivity in early schizophrenia and major depressive disorder: a resting functional MRI evaluation of large-scale brain network models. 10:1-14 Frontiers in Human Neuroscience. (March 2016).
Gilbert, K.M., Gati, J.S., Barker, K., Everling, S. and Menon, R.S. Optimized parallel transmit and receive radiofrequency coil for ultrahigh-field MRI of monkeys. NeuroImage 125:153-61. (January 2016).
Manning K.Y., Menon R.S., Mesterman R., Gorter J.W., Switzer L., Campbell C., Fehlings D. Neuroplastic sensorimotor resting state network reorganization in children with hemiplegic cerebral palsy treated with constraint-induced movement therapy. Journal of Child Neurology 31(2):220-6. (February 2016).
Connell I.R., Gilbert K.M., Abou-Khousa M.A., Menon R.S. Design of a Parallel Transmit Head Coil at 7T With Magnetic Wall Distributed Filters. IEEE Trans Med Imaging. 34(4):836-45. (April 2015).
Connell I.R., Gilbert K.M., Abou-Khousa M.A., Menon R.S. MRI RF array decoupling method with magnetic wall distributed filters. IEEE Trans Med Imaging. 34(4):825-35. (April 2015).
Liu J., Rudko D.A., Gati J.S., Menon R.S., Drangova M. Inter-echo variance as a weighting factor for multi-channel combination in multi-echo acquisition for local frequency shift mapping. Magn Reson Med. 73(4):1654-61 (April 2015).
Hutchison R.M., Hashemi N., Gati J.S., Menon R.S., Everling S. Electrophysiological signatures of spontaneous BOLD fluctuations in macaque prefrontal cortex. Neuroimage. 113:257-267. doi: 10.1016/j.neuroimage.2015.03.062. (March 2015).
Manning K.Y., Fehlings D., Mesterman R., Gorter J.W., Switzer L., Campbell C., Menon R.S. Resting State and Diffusion Neuroimaging Predictors of Clinical Improvements Following Constraint-Induced Movement Therapy in Children With Hemiplegic Cerebral Palsy. J Child Neurol. 30(11):1507-14. pii: 0883073815572686. (March 2015).

Funding

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Paul Minda

Paul Minda

Contact information

Tel: (519) 661-2111 x84689
Email:jpminda@uwo.ca
Website: The Categorization Lab

Department

Psychology

Research Areas

  • My research seeks to understand how people learn about categories and concepts and how conceptual structure influences thinking, reasoning, and decision making. I am also interested in cognitive aging and cognitive effects of mindfulness meditation.

Publications

Rabi, R. R. & Minda, J. P. (2016). Category learning in older adulthood: A study of the Shepard, Hovland, and Jenkins (1961) tasks. Psychology and Aging, 31. 185-197.
Minda, J. P. & *Rabi, R. R. (2015). Ego depletion interferes with rule-defined category learning but not non-rule-defined category learning. Frontiers in Psychology, 6, 35. doi: 10.3389/fp-syg.2015.00035
Rabi, R. R., *Miles, S. J., & Minda, J. P. (2015). Learning categories via rules and similarity: comparing adults and children. Journal of Experimental Child Psychology, 131, 149-169.
Miles, S. J., Matsuki, K., & Minda, J. P. (2014). Continuous executive function disruption interferes with application of an information integration categorization strategy. Attention, Perception, & Psychophysics, 76, 1318-1334.
Rabi, R. R. & Minda, J. P. (2014). Rule-based category learning in children: The role of age and executive functioning. PLoS ONE 9(1): e85316. doi:10.1371/journal.pone.0085316.
Goldszmidt, M., Minda, J. P., & Bordage, G. (2013). What physicians reason about during clinical encounters: Time to be more explicit. Academic Medicine 88, 230-337.
Miles, S. J. & Minda, J. P. (2012). Perceptual fluency can be used as a cue for categorization decisions. Psychonomic Bulletin & Review, 19, 737-742.
Goldszmidt, M., Minda, J. P., *Devantier, S. L., Skye, A. L., & Woods, N. N. (2011). Expanding the basic science debate: The role of physics knowledge in interpreting clinical findings, Advances in Health Sciences Education, 17, 547-555. (Note: Goldszmidt and Minda were listed alphabetically as co-first authors; I served as corresponding author)
Miles, S. J. & Minda, J. P. (2011). The effects of concurrent verbal and visual tasks on category learning. Journal of Experimental Psychology: Learning, Memory, and Cognition, 37, 588-607.
Nadler, R. T. D., *Rabi, R. R., & Minda, J. P. (2010). Better mood and better performance: learning rule-described categories is enhanced by positive mood. Psychological Science, 21, 1170-1776.

Funding

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Derek Mitchell

Derek Mitchell

Contact information

Tel: (519) 661-2111 x84862
Email:dmitch8@uwo.ca
Website: Mitchell Lab

Department

Anatomy & Cell Biology, Psychiatry

Research Areas

  • Determining how dissociable neural systems integrate emotion with cognition and behaviour

Publications

Greening, S.G., Finger, E.C., & Mitchell, D.G.V. (2011). Parsing decision making processes in prefrontal cortex: Response inhibition, overcoming learned avoidance, and reversal learning. NeuroImage, 54(2), 1432-1441. doi:10.1016/j.neuroimage. 2010.09.017.
Mitchell, D.G.V. (2010). The nexus between decision making and emotion regulation: A review of convergent neurocognitive substrates. Behavioral Brain Research, 217(2011), 215-231. doi:10.1016/j.bbr.2010.10.030.
Amting J.M., Greening S.G., Mitchell D.G.V. (2010). Multiple mechanisms of consciousness: The neural correlates of emotional awareness. Journal of Neuroscience, 30(30), 10039-47.
Rich, B.A., Brotman, M.A., Dickstein, D.P., Mitchell, D.G.V., Blair, R.J.R., & Leibenluft, E. (2010). Deficits in Attention to Emotional Stimuli Distinguish Youth with Severe Mood Dysregulation from Youth with Bipolar Disorder. Journal of Abnormal Child Psychology, Epub ahead of print.
Mitchell, D.G.V., Luo, Q., Avny, S.B., Kasprzycki, T., Gupta, K., Chen, G., Finger, E.C., Blair, R.J.R. (2009). Adapting to dynamic stimulus-response values: Differential contributions of inferior frontal, dorsomedial and dorsolateral regions of prefrontal cortex to decision making. Journal of Neuroscience, 29(35), 10827-10834.
Amting, J.M., Miller, J.E., Chow, M., & Mitchell, D.G.V. (2009). Getting mixed messages: The impact of conflicting social signals on the brain's target emotional response.NeuroImage, 47, 1950-1959.

Funding

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J. Bruce Morton

J. Bruce Morton

Contact information

Tel: (519) 661-2111 x84795
Email:bmorton3@uwo.ca
Website: Cognitive Development and Neuroimaging Laboratory

Department

Psychology

Research Areas

  • The development of self-regulation and control, and its link with changes in brain function in children and teens

Publications

Meinz, P., Morton, J. B., Pederson, D. R., & Moran, G (in press). Biases in attention for social stimuli in children are associated with patterns of infant attachment in infancy: A brief report. Social Development.
Morton, J. B. (2015). Still waiting for real answers. Cortex, 73, 352-353.
Hutchison, R. M. & Morton, J. B. (2016). It’s a matter of time: Reframing the development of cognitive control as a modification of the brain’s temporal dynamics. Developmental Cognitive Neuroscience, 18, 70-77.
Hutchison, R. M. & Morton, J. B. (2015). Tracking the brain’s functional coupling dynamics over development. Journal of Neuroscience, 35(17), 6849-6859.
Hosseini-Kamkar, N., & Morton, J. B. (2014). Sex differences in self-regulation: An evolutionary perspective. Frontiers in Neuroscience, 8.
Morton, J. B. (2014). Dynamic field theory and executive functions: Lending explanation to current theories of development. Monograph of the Society for Research in Child Development, 79(2), 116-124.
Morton, J. B. (2014). Sunny review casts a foreboding shadow over status quo bilingual advantage research. Applied Psycholinguistics, 35(5), 929-931.
Turnbull, K, Reid, G. J. & Morton, J B. (2013). Behavioral sleep problems and their impact on developing executive function in children. Sleep, 36(7), 1077-1084.
DeBenedictis, B. A., & Morton, J. B. (2013). A Method for Investigating Age-Related Differences in the Functional Connectivity of Cognitive Control Networks Associated with DCCS performance. Journal of Visual Experiments
Ezekiel, F, Bosma, R, & Morton, J.B. (2013). Dimensional Change Card Sort performance associated with age-related differences in functional connectivity of lateral prefrontal cortex. Developmental Cognitive Neuroscience, 5, 20-40.

Funding

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Adrian Owen

Adrian Owen

Contact information

Tel: (519) 661-2111 x84672
Email:uwocerc@uwo.ca
Website: Owen Lab

Department

Psychology, Anatomy & Cell Biology, Physiology & Pharmacology

Research Areas

  • Understanding the effects of brain injury in order to improve diagnosis and early detection and to find possible new treatments

Publications

Owen, A.M., Stern, C. E., Look, R. B., Tracey, I., Rosen, B. R. and Petrides, M. Functional organisation of spatial and non-spatial working memory processes within the human lateral frontal cortex. Proc. Nat. Acad. USA. 95(13), 7721-7726, 1998.
Bor, D., Duncan, J., Wiseman, R.J. and Owen, A.M. Encoding strategies dissociates prefrontal activity from working memory demand. Neuron, 37(2), 361-367, 2003.
Owen, A.M., Coleman, M.R., Davis, M.H., Boly, M., Laureys, S. and Pickard, J.D. Detecting awareness in the vegetative state. Science, 313, 1402, 2006.
Owen, A.M., Hampshire, A., Grahn, J.A., Stenton, R., Dajani, S., Burns, A. S., Howard, R. J. and Ballard, C.G. Putting brain training to the test. Nature 465, 775-779, 2010.
Cruse, D., Chennu, S., Chatelle, C., Bekinschtein, T.A., Fernandez-Espejo, D., Pickard, D.J., Laureys, S. and Owen, A.M. Bedside detection of awareness in the vegetative state. The Lancet, 378(9809):2088-94, 2011.
Hampshire, A., Highfield, R., Parkin, B. and Owen, A.M. Fractioning human intelligence. Neuron, Vol.76, 6:1225-1237, 2012.
Owen, A.M. Detecting consciousness: A role for neuroimaging. Annual Review of Psychology, 64:109-33, 2013.
Naci, L. & Owen, A.M. Making every word count for vegetative patients. JAMA Neurology, 70(10):1235-41, 2013.
Fernandez Espejo, D. & Owen, A.M. Detecting Awareness after Severe Brain Injury. Nature Reviews Neuroscience, 14(11):801-9, 2013.
Naci, L., Cusack, R., Anello, M. and Owen, A.M. A common neural code for similar conscious experiences in different individuals. PNAS, DOI:10.1073/pnas.1407007111, 2014.

Funding

  • Canada Excellence Research Chair (CERC)
  • Canadian Foundation for Innovation (CFI)
  • Canadian Institutes of Health Research (CIHR)
  • Natural Sciences and Engineering Research Council of Canada (NSERC)
  • James S. McDonnell Grant (USA)

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Dante Pirouz

Dante Pirouz

Contact information

Tel: (519) 661-3886 x83886
Email:dpirouz@ivey.ca
Website: Pirouz Lab

Affiliation

Richard Ivey School of Business

Research Areas

  • Using both neuroscience and cognitive science tools and theories to examine the "dark side" of risky consumer behaviour

Publications

Pirouz, Dante M., Mike Kamens, Ingrid Martin, Sayantani Mukherjee, Kelly Haws, Ann M. Mirabito, Aditi Grover, Scott Davis, and Justine Rapp (Forthcoming 2012), "On the Road to Addiction: Do Marketing Cues Influence This Path?," Journal of Research for Consumers.
Pirouz, Dante M., Mike Kamens, Ingrid Martin, Sayantani Mukherjee, Kelly Haws, Ann M. Mirabito, Aditi Grover, Scott Davis, and Justine Rapp (Forthcoming 2012), "An Addictive Consumption Framework For Transformative Consumer Researchers," Journal of Business Research.
Pechmann, Cornelia (Connie), Elizabeth Moore, Alan Andreasen, Paul M. Connell, Daniel Freeman, Meryl Gardner, Deborah Heisley, Craig Lefebvre, Dante M. Pirouz and Robin Soster (2011), "Learning about At Risk Consumers: Research Challenges and Opportunities," Journal of Public Policy and Marketing.
Litt, Ab, Dante M. Pirouz, and Baba Shiv (2011), "Neuroscience and Addictive Consumption," in Transformative Consumer Research for Personal and Collective Well Being:  Reviews and Frontiers, ed. David Mick and Cornelia (Connie) Pechmann, London, UK: Taylor & Francis.

Funding

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Andrew Pruszynski

Andrew Pruszynski

Contact information

Tel: (519) 663-5777 x24384
Email: andrew.pruszynski@uwo.ca
Website: Pruszynski Lab

Department

Physiology & Pharmacology, Psychology

Research Areas

  • Neural mechanisms of sensory perception and motor control

Publications

Omrani, M., Murnaghan, C., Pruszynski, J.A., Scott, S.H. Distributed task-specific processing of somatosensory feedback for voluntary motor control. eLife. In press.
Pruszynski, J.A., Johansson, R.S., Flanagan, J.R. A rapid tactile-motor reflex automatically guides reaching toward handheld objects. Current Biology 26: 788-792.
Hemming, E., Lillicrap, T.P., Omrani, M., Herter, T.M., Pruszynski, J.A., Scott, S.H. Load classified neurons in primary motor cortex predict muscle activation patterns in a reaching task. Journal of Neurophysiology. In press.
Weiler, J., Gribble, P.L., Pruszynski, J.A. (2015) Goal-dependent modulation of the long-latency stretch response at the shoulder, elbow and wrist muscles. Journal of Neurophysiology 14:3242-54.
Pruszynski, J.A., Johansson, R.S. (2014). Edge-orientation processing in first-order tactile neurons. Nature Neuroscience 34: 4608-17.
Omrani, M., Pruszynski, J.A., Murnaghan, C.D., Scott, S.H. (2014). Perturbation-evoked responses in primary motor cortex are modulated by behavioral context. Journal of Neurophysiology 112: 2985-3000.
Pruszynski, J.A. (2014). Primary motor cortex and fast feedback responses to mechanical perturbations: a primer on what we know now and some suggestions on what we should find out next. Frontier in Integrative Neuroscience 8:72. Review.
Johansson, A.S., Pruszynski, J.A., Edin, B.B., Westberg, K.G. (2014) Biting intentions modulate digastric reflex responses to sudden unloading of the jaw. Journal of Neurophysiology 112:1067-73.
Pruszynski, J.A., Omrani, M., Scott, S.H. (2014) Goal-dependent modulation of fast feedback responses in primary motor cortex. Journal of Neuroscience 34: 4608-17. Review.
Nordmark, P., Pruszynski, J.A., Johansson, R.S. (2012) BOLD responses to tactile stimuli in visual and auditory cortex depend on the frequency content of stimulation. Journal of Cognitive Neuroscience 24:2120-34.

Funding

    • Early Researcher Award, Government of Ontario
    • Leader's Fund, Canada Foundation for Innovation

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Lisa Saksida

Lisa Saksida

Contact information

Tel: (519) 661-2111 x83604
Email: lsaksida@uwo.ca
Website: TCNLab

Department

Physiology & Pharmacology, Psychology

Research Areas

  • Cognition, how the healthy brain does it, what goes wrong in neurodegenerative and neuropsychiatric disease, and identifying targets for therapy
  • Improving preclinical-to-clinical translation

Publications

Horner, A.E., Heath, C.J., Hvoslef-Eide, M., Kent, B.A., Kim, C.H., Nilsson, S., Alsiö, J., Oomen, C.A., Holmes, A., Saksida, L.M., & Bussey, T.J. (2013) The touchscreen operant platform for testing learning and memory in rats and mice. Nature Protocols, 8(10):1961-84. PMCID: PMC3914026
Oomen, C.A., Hvoslef-Eide, M., Heath, C.J., Mar, A.C., Horner, A.E., Bussey, T.J., & Saksida, L.M. (2013) The touchscreen operant platform for testing working memory and pattern separation in rats and mice. Nature Protocols, 8(10):2006-21. PMCID: PMC3982138
Mar, A.C., Horner, A.E., Nilsson, S., Alsiö, J., Kent, B.A., Kim, C.H., Holmes, A., Saksida, L.M., & Bussey, T.J. (2013) The touchscreen operant platform for assessing executive function in rats and mice. Nature Protocols, 8(10):1985-2005
Brigman J.L., Daut, R. Wright, T., Gunduz-Cinar, O., Graybeal, C., Jiang, Z., Saksida, L.M., Jinde, S., Pease, M., Bussey, T.J., Lovinger, D.M., Nakazawa, K., & Holmes, A. (2013) GluN2B in corticostriatal circuits governs choice learning and choice shifting. Nature Neuroscience, 16(8):1101-10. PMC3725191
Romberg,C., Yang, S., Melani, R., Andrews, M.R., Horner, A.E., Spillantini, M.G., Bussey, T.J., Fawcett, J.W., Pizzorusso, T. & Saksida, L.M. (2013) . Depletion of perineuronal nets enhances recognition memory and long-term depression in the perirhinal cortex. Journal of Neuroscience, 33 (16): 7057-7065. PMCID: PMC3655688
Ryan, T.J., Kopanitsa, M.V., Indersmitten, T., Nithianantharajah, J., Afinowi, N.O., Pettit, C., Stanford, L.E., Sprengel, R., Saksida, L.M., Bussey T.J., O’Dell, T.J., Grant, S.G.N., and Komiyama, N.H. (2013) Genetic exchange of evolutionarily derived GluN2A and GluN2B cytoplasmic domains identifies shared and unique contributions to vertebrate behavior and synaptic plasticity, Nature Neuroscience, 16(1): 25-32. PMCID: PMC3979286
Barense, M.D., Groen, I.I.A., Lee, A.C.H., Yeung, L-K, Brady, S.M., Gregori, M., Kapur, N., Bussey, T.J., Saksida, L.M.* & Henson, R.N.A.* (2012). Intact memory for irrelevant information impairs perception in amnesia. Neuron, 75(1):157-167. PMC3657172 *These authors contributed equally. See Preview in Neuron by M. Baxter 75(1):8-10
Romberg, C., McTighe, S.M., Heath, C.J., Whitcomb, D., Cho, K., Bussey, T.J. & Saksida, L.M. (2012) False recognition in a mouse model of Alzheimer’s disease: rescue with sensory restriction and memantine. Brain, 135:2103-2114. PMC3381719
Romberg C., Mattson. M.P., Mughal, M.R., Bussey T.J., Saksida L.M. (2011). Attentional impairments in the triple transgenic mouse model of Alzheimer’s disease: Rescue with donepezil (Aricept). Journal of Neuroscience, 31, 3500-3507. PMC3066152
McTighe, S.M., Cowell, R.C., Winters, B.D., Bussey, T.J. & Saksida, L.M. (2010). Paradoxical false memory for objects after brain damage. Science, 330 (6009): 1408-10. See commentary in Science by H. Eichenbaum 330: 1331 - 1332 (2010). Recommended by Faculty of 1000 as “Must Read”, see www.facultyof1000.com. Free full text.
Cowell, R., Bussey, T.J. & Saksida, L.M. (2010). Components of recognition memory: dissociable cognitive processes or just differences in representational complexity? Hippocampus, 20(11):1245-62
Cowell, R., Bussey, T.J. & Saksida, L.M. (2010). Functional dissociations within the ventral object processing pathway: cognitive modules or a hierarchical continuum? Journal of Cognitive Neuroscience, 22(11):2460-79
Murray, E.A., Bussey, T.J. & Saksida, L.M. (2007). Visual perception and memory: A revised view of medial temporal lobe function in primates and rodents. Annual Review of Neuroscience, 30, 99-122
Saksida, L.M., Bussey, T. J., Buckmaster, C. A. & Murray, E.A. (2007). Impairment and facilitation of transverse patterning after lesions of the perirhinal cortex and hippocampus, respectively. Cerebral Cortex, 17, 108-115
Cowell, R.C., Bussey, T.J., & Saksida, L.M. (2006). Why does brain damage impair memory? A connectionist model of object recognition memory in perirhinal cortex. Journal of Neuroscience, 26, 12186-97
Morton, A.J., Skillings, E., Bussey, T.J. & Saksida, L.M. (2006). Measuring cognitive deficits in disabled mice using an automated interactive touchscreen system. Nature Methods, 3, 767. Awarded the "highly commended" prize in the NC3Rs 3Rs competition, 2008
Graham, K.S., Scahill, V. L., Hornberger, M., Barense, M.D., Lee, A.C.H., Bussey, T.J. & Saksida, L.M. (2006). Abnormal categorization and perceptual learning in patients with hippocampal damage. Journal of Neuroscience, 26, 7547-54
Barense, M.D., Bussey, T.J., Lee, A.C.H., Rogers, T.T., Davies, R.R., Saksida, L.M., Murray, E.A., & Graham, K.S. (2005). Functional specialization in the human medial temporal lobe. Journal of Neuroscience, 25, 10239-46
>Bussey, T. J. and Saksida, L.M. (2002). The organization of visual object representations: a connectionist model of effects of lesions in perirhinal cortex. European Journal of Neuroscience 15: 355-64. (Authorship in alphabetical order: both authors contributed equally.)
Bussey, T.J., Saksida, L.M. & Rothblat, L.A. (2001). Discrimination of computer-graphic stimuli by mice: A method for the behavioral characterization of transgenic and gene-knockout models. Behavioral Neuroscience, 115: 957-960

Funding

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Andrea Soddu

Andrea Soddu

Contact information

Tel: (519) 661-2111 x82669
Email: asoddu@uwo.ca
Website: Soddu Lab

Department

Physics & Astronomy

Research Areas

  • Study of resting state fMRI connectivity in altered states of consciousness
  • Modelling of the structure-function relationship in the human brain

Publications

Bonhomme V, Vanhaudenhuyse A, Demertzi A, Bruno MA, Jaquet O, Bahri MA, Plenevaux A, Boly M, Boveroux P, Soddu A, Brichant JF, Maquet P, Laureys S. Resting state network-specific breakdown of functional connectivity during ketamine alteration of consciousness, Anesthesiology, in press.
Di Perri C, Bahri MA, Amico E, Thibaut A, Heine L, Antonopoulos G, Charland-Verville V, Wannez S, Gomez F, Hustinx R, Tshibanda L, Demertzi A & Soddu A & Laureys S. Neural correlates of consciousness in patients who have emerged from a minimally conscious state: a cross-sectional multimodal imaging study. Lancet Neurol. 2016, S1474-4422(16)00111-3
Guldenmund P & Gantner IS, Baquero K, Das T, Demertzi A, Boveroux P, Bonhomme V, Vanhaudenhuyse A, Bruno MA, Gosseries O, Noirhomme Q, Kirsch M, Boly M, Owen AM, Laureys S, Gómez F & Soddu A. Propofol-Induced Frontal Cortex Disconnection: A Study of Resting-State Networks, Total Brain Connectivity, and Mean BOLD Signal Oscillation Frequencies. Brain Connect. 2016, 6(3):225-37.
Guldenmund P, Soddu A, Baquero K, Vanhaudenhuyse A, Bruno MA, Gosseries O, Laureys S, Gómez F. Brain damage in patients with disorders of consciousness: a voxel-based morphometry study. Brain Inj. 2016, 30(3):343-52.
Soddu A & Gómez F, Heine L, Di Perri C, Bahri MA, Voss HU, Bruno MA, Vanhaudenhuyse A, Phillips C, Demertzi A, Chatelle C, Schrouff J, Thibaut A, Charland-Verville V, Noirhomme Q, Salmon E, Tshibanda JF, Schiff ND, Laureys S. Correlation between resting state fMRI total neuronal activity and PET metabolism in healthy controls and patients with disorders of consciousness. Brain Behav. 2015, 6(1):e00424.
Heine L, Bahri MA, Soddu A, Laureys S, Ptito M and Kupers R. Prevalence of increases in functional connectivity in visual, somatosensory and language areas in congenital blindness. Frontiers in Neuroanatomy 2015, 9.
Demertzi A, Antonopoulos G, Heine L, Voss H, Crone JS, Kronbichler M, Trinka E, Los Angeles C, Bahri AM, Philips C, Di Perri C, Gomez F, Tshibanda L, Vanhaudenhuyse A, Charland-Verville V, Soddu A, Schiff N, Whitfield-Gabrieli S and Laureys S. Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients. Brain 2015, 138 (Pt 9): 2619-31.
Cavaliere C, Aiello M, Di Perri C, Fernandez-Espejo D, Owen AM, Soddu A. Diffusion tensor imaging and white matter abnormalities in patients with disorders of consciousness. Frontiers in Human Neuroscience 2015; 8, 1028.
Liegeois R, Ziegler E, Geurts P, Gomez F, Bahri MA, Phillips C, Soddu A, Vanhaudenhuyse A, Laureys S, Sepulchre R. Cerebral functional connectivity periodically (de) synchronizes with anatomical constraints. Brain Struct Funct. 2015 Jul 22.
Di Perri C, Heine L, Amico E, Soddu A, Laureys S, Demertzi A. Technology-based assessment in patients with disorders of consciousness. Ann Ist Super Sanita 2014; 50(3):209-20.

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Ryan Stevenson

Ryan Stevenson

Contact information

Tel: 519-661-2111
Email: rsteve28@uwo.ca
Website: Available soon

Department

Psychology

Research Areas

  • Sensory processing and perceptual binding
  • Sensory perception in autism spectrum disorders
  • How sensory perception impacts cognitive processing
  • Sensory perception in cochlear implant users

Publications

Stevenson, R. A., Sun, S. Z., Hazlett, N., Cant, J. S., Barense, M. D., & Ferber, S. (2016). Seeing the forest and the trees: Default local processing in individuals with high autistic traits does not come at the expense of global attention. Journal of Autism and Developmental Disorders, 1-15.
Baum, S. H., Stevenson, R. A. (In Press). Early patterns of eye gaze and brain connectivity initiate developmental cascades in visual cognitive function. Frontiers in Psychology.
Altieri, N., Wenger, M. J., Wallace, M. T., & Stevenson, R. A. (2016). Does Number of Perceptions or Cross-Modal Auditory Cueing Influence Audiovisual Processing Speed? The American Journal of Psychology, 129(1), 11-21.
Noel, JP., DeNiear, M., Stevenson, R. A., Alais, D., & Wallace, M. T. (n Press) Rapid audio-visual temporal recalibration across stimuli-complexities: low-level deficits in ASD. Autism Research.
Krueger-Fister, J., Stevenson, R. A., Barnett, Z. P., & Wallace, M.T. (2016). Multisensory interactions across stimulus effectiveness and temporal synchrony. Neuropsychologia.
Nidiffer, A. R., Stevenson, R. A., Krueger-Fister, J., Barnett, Z. P., & Wallace, M.T. (2016). Multisensory interactions across stimulus effectiveness and spatial location. Neuropsychologia.
Stevenson, R. A., Segers, M., Ferber, S., Barense, M. D., Camarata, S., & Wallace, M. T. (2015). Keeping time in the brain: Autism spectrum disorder and audiovisual temporal processing. Autism Research. DOI: 10.1002/aur.1566
Stevenson R. A., Segers, M., Ferber, S., Barense, M. D., Wallace, M. T. (2016). The impact of multisensory integration deficits on speech perception in children with autism spectrum disorders. Frontiers in Psychology, 5, 379.
Stevenson, R. A., Nelms, C., Baum, S., Zurkowsky, L., Barense, M.D., Newhouse, P., & Wallace, M.T. (2015) Deficits in audiovisual speech perception in normal aging emerge at the level of whole-word recognition. Neurobiology of Aging, 36(1), 283-291.
Baum, S. H., Stevenson, R. A., & Wallace, M. T. (2015). Behavioral, perceptual, and neural alterations in sensory and multisensory function in autism spectrum disorder. Progress in Neurobiology, 134, 140-160.

Funding

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Brian Timney

Brian Timney

Contact information

Tel: (519) 661-2111 x86694
Email: timney@uwo.ca
Website: Timney Lab

Department

Psychology

Research Areas

  • Human vision, with a focus on the effect of alcohol, and binocular vision
  • The visual system in horses and camels

Publications

Mueller, A.S. & Timney, B. (2016). Visual Acceleration Perception for Simple and Complex Motion Patterns. PLoS ONE, 11(2): e0149413. doi:10.1371/journal.pone.0149413.
Mueller, A.S. & Timney, B. (2014). Effects of radial direction and eccentricity on acceleration Perception. Perception, 43, 805-810. doi:10.1068/p7776
Johnston K, & Timney B, 2013, "Alcohol and lateral inhibitory interactions in human vision" Perception, 42, 1301 – 1310
Johnston, K.D., Timney, B. , & Goodale. M. . (2013). Acute alcohol consumption impairs controlled but not automatic processes in a psychophysical pointing. Public Library of Science One, doi:10.1371/journal.pone.0068682.
Johnston, K.D. & Timney, B. (2008). Effects of acute alcohol consumption on a psychophysical measure of lateral inhibition in human vision. Vision Research, 48, 1539-1544.
Khan, S., & Timney B. (2007) Alcohol does not affect dark adaptation or luminance increment thresholds. Journal of Studies on Alcohol and Drugs, 68, 493-502.
Khan, S. & Timney, B. (2007). Alcohol slows interhemispheric transmission, increases the flash lag effect, and prolongs masking: Evidence for a slowing of neural processing and transmission. Vision Research, 47, 1821-1832.
Geisbauer, G., Griebel, U., Schmid, A. & Timney, B. (2004). Brightness discrimination and neutral test point in the horse. Canadian Journal of Zoology, 82, 660-670.
Khan, S. A.., Ford, K., Timney, B. & Everling, S. (2003). Effects of alcohol on the anti-saccade task. Experimental Brain Research, 150, 68-74.
Harman, A., Dann, J., Ahmat, A., Macuda, T., Johnston, K., & Timney, B. (2001). The retinal ganglion cell layer and visual acuity of the camel. Brain, Behavior and Evolution, 58, 15-27.

Funding

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Tutis Vilis

Tutis Vilis

Contact information

Tel: (519) 661-3830 x83830
Email:tutis.vilis@schulich.uwo.ca
Website: Vilis Lab

Department

Medical Biophysics, Ophthalmology, Physiology & Pharmacology, Psychology

Research Areas

  • The function and interaction of brain areas involved in vision and directing motor actions

Publications

Strother, L.,Lavell, C. and Vilis, T. (2012). Figure-ground representation and its decay in primary visual cortexJournal of Cognitive Neuroscience (doi: 10.1162/jocn_a_001905.
Strother L, Mathuranath PS, Aldcroft A, Lavell C, Goodale MA, Vilis T. (2011). Face Inversion Reduces the Persistence of Global Form and its Neural Correlates. PLoS ONE6(4): e18705. doi:10.1371/journal.pone.0018705.
Strother L, Aldcroft A, Lavell C, Vilis T. (2010). Equal Degrees of Object Selectivity for Upper and Lower Visual Field StimuliJournal of Neurophysiology 104:2075-81.
Wong, Y.J., Aldcroft, A.J., Large, M.-E., Culham, J.C., & Vilis, T. (2009). The Role of Temporal Synchrony as a Binding Cue for Visual Persistence in Early Visual Areas: An fMRI Study. Journal of Neurophysiology, 102, 3461-3468.
Large, M.-E., Culham, J.C., Kuchinad, A., Aldcroft, A., & Vilis, T. (2008). fMRI reveals greater within- than between-hemifield integration in the human lateral occipital cortex.European Journal of Neuroscience, 27, 3299-3309.
Fernandez-Ruiz, J., Goltz, H.C., Desouza, J.F., Vilis, T., & Crawford, J.D. (2007). Human Parietal "Reach Region" Primarily Encodes Intrinsic Visual Direction, Not Extrinsic Movement Direction, in a Visual-Motor Dissociation Task. Cerebral Cortex, 17(10), 2283-92.

Funding

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