David Smith, PhD
Genome evolution and genetic diversity of microbial eukaryotes
Biological & Geological Sciences 3028
Biological & Geological Sciences 3027
(519) 661-2111 x 86482
We study genome architecture, genetic diversity, and the evolutionary forces that fashion genes and chromosomes. We’re interested in how nonadaptive processes shape genomes, including their nucleotide composition, compactness, conformation, chromosome number and telomeres. Much of our research employs protists (microbial eukaryotes). Protists have among the most diverse and eccentric genomes in the biological world, yet they are generally an untapped resource for studying genome evolution. We love weird genomes and trying to understand how they got that way.
Degrees and Institutions
- B.Sc. (Biology) Acadia University
- Ph.D. (Genetics and Evolution) Dalhousie University
- Biology 4200B - Genome Evolution
- Biology 4441F - Special Topics in Evolution
- Smith DR, Hua J, Archibald JM, Lee RW. Palindromic genes in the linear mitochondrial genome of the nonphotosynthetic green alga Polytomella magna. Genome Biol Evol. In press.
- Smith DR, James ER (2013) What’s in a name? A lot if you’re a little known microbe. BioScience. In press.
- Vinogradov SN, Bailly X, Smith DR, Tinajero-Trejo M, Poole RK, Hoogewijs D (2013) Microbial eukaryotic globins. Adv Microb Physiol. In press.
- Smith DR (2013) Death of the genome paper. Front Genet. 4:72.
- Smith DR, Keeling PJ (2013) Gene conversion shapes linear organelle genome architecture. Genome Biol Evol. In press.