Western University BiologyWestern Science

Sheila Macfie, PhD

Mechanisms of Metal Tolerance


Sheila Macfie Position:
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Associate Professor
Biological & Geological Sciences 2051
Biological & Geological Sciences 2061
(519) 661-2111 x 86487
519 661-3935
smacfie@uwo.ca
http://www.uwo.ca/biology/faculty/macfie/

Many plants have a remarkable ability to withstand high concentrations of potentially toxic metals in their environment. A better understanding of the biochemical and physiological mechanisms that permit such tolerance may provide valuable information regarding the use of plants to restore contaminated areas.

Current projects involve edible plants, including wheat (Triticum spp) barley (Hordeum vulgare) and lettuce (Lactuca sativa), as well as Arabidopsis thaliana.  The approaches that we are taking include: (1) investigate the production and exudation of organic compounds as a mechanism to detoxify metal ions, (2) determine the localization of metal ions at the subcellular level, (3) model the movement of metals from the soil into the plant and (4) identify the relationship between metal toxicity and a number of biochemical pathways that mediate plant stress.

Degrees and Institutions

Teaching

On Sabbatical leave

Recent Publications