Dr. Jim Staples
Comparative Physiology and Biochemistry

PUBLICATIONS 2011-
for 1995-2010 click here

 

Gallagher, K. and Staples, J.F. Metabolism of brain cortex and cardiac muscle mitochondria in hibernating thirteen-lined ground squirrels (Ictidomys tridecemlineatus). Physiol. Biochem. Zool. in press.

Brown, J, Marshall, K., Staples, J. 2012. Differences in tissue concentrations of hydrogen peroxide in the roots and cotyledons of annual and perennial species of flax (Linum). Botany. 90(10): 1015-1027

Suri L., McCaig L., Picardi, M., Ospina, O., Veldhuizen, R., Staples, J., Possmayer, F., Yao, L., Perez-Gil, J., Orgeig, S. 2012. Adaptation to low body temperature influences pulmonary surfactant composition thereby increasing fluidity while maintaining appropriately ordered membrane structure and surface activity. BBA-Biomembranes. 1818:1581-1589.

MacMillan, H.A, Williams, C.M., Staples, J.F. and Sinclair, B.J. 2012. Metabolism and energy supply below the critical thermal minimum of a chill-susceptible insect. J. Exp. Biol. 215:1366-1372.

Brown, J.C.L., Chung, D.J., Belgrave, K.R. and Staples, J.F. Mitochondrial metabolic suppression and reactive oxygen species production in liver and skeletal muscle of hibernating thirteen-lined ground squirrels. 2012. Am. J. Physiol. 302:R15-R28.

Staples, J.F. Maintaining metabolic balance in mammalian hibernation and daily torpor. 2011. in Nowakowska, A. and M. Caputa (eds.) Hypometabolism: strategies of survival in vertebrates and invertebrates. Research Signpost, Kerala, India. pp. 95-115.

Brown, J.C.L. and Staples, J.F. 2011. Suppression of mitochondrial metabolism during daily torpor and fasting in house mice (Mus musculus) and dwarf Siberian hamsters (Phodopus sungorus): consequences for reactive oxygen species release. Physiol. Biochem. Zool. 84:467-480.

Armstrong C., Thomas, R., Price, E.R., Guglielmo, C. G. and Staples, J. F. 2011. Remodeling mitochondrial membrane during arousal from hibernation. Physiol. Biochem. Zool. 84:438-449.

Chung, D., Lloyd, G.P., Thomas, R.H., Guglielmo, C.G. and Staples, J.F. 2011. Mitochondrial respiration and succinate dehydrogenase are suppressed early during entrance into a hibernation bout, but membrane remodeling is only transient. J. Comp. Physiol. B 181(5):699-711.

Price, E.R., Staples, J.F., Milligan, C.L. and Guglielmo, C.G. 2011. Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles. J. Comp. Physiol. B. 181(4):565-573.

PUBLICATIONS 1995-2010

Armstrong, C. and Staples, J.F. 2010. The role of succinate dehydrogenase and oxaloacetate in mitochondrial metabolism during mammalian hibernation and arousal. J. Comp. Physiol. B. 180:775-783.

Brown, J.C.L. and Staples, J.F. 2010. Mitochondrial metabolism during fasting-induced daily torpor in mice (Mus musculus). Biochim. Biophys.
Acta-Bioenerg. 1797(4):476-486.

Brown, J.C.L., McClelland, G.B., Faure, P.A., Klaiman, J.M. and Staples,
J.F. Mechanisms of reduced ROS production in long-lived species. 2009.
Mech. Ageing Dev. 130:467-476.

McDonald, A.E., Vanlerberghe, G.C. and Staples, J.F. Alternative oxidase
in animals: Unique characteristics and taxonomic distribution. 2009. J.
Exp. Biol. 212:2627-2634

Staples, J.F. and Buck, L.T. 2009. Matching metabolic supply and demand in energy-stressed animals. Comp. Biochem. Physiol. A. 153:95-105.

Page, M.M., C. Peters, J.F. Staples and Stuart J.A. 2009. Intracellular superoxide dismutases are not globally upregulated during hibernation in the major oxidative tissues in the 13-lined ground squirrel Spermophilus tridecemlineatus. Comp. Biochem. Physiol. A 152:115-122.

Staples J.F. and J.C.L. Brown. 2008. Mitochondrial metabolism in hibernation and daily torpor: a review. J. Comp. Physiol. B. 178:811-827.

Gerson, A.R., J.C.L. Brown, R. Thomas, M.A. Bernards and J.F. Staples.
2008. The effect of dietary polyunsaturates on mitochondrial metabolism in hibernation. J. Exp. Biol. 211: 2689-2699.

Staples, J.F., Kajimura, M., Wood, C.M., Patel, M., Ip, Y.K., and McClelland, G.B. (2008) Enzymatic and mitochondrial responses to 5 months of aerial exposure in the slender lungfish (Protopterus dolloi). J. Fish Biol.73:608-622.

Ellard, J.P., McCudden, C.R. Tanega, C. James, K.A., Ratkovic, S., Staples, J.F., Wagner, G.F. 2007. The respiratory effects of stanniocalcin-1 (STC-1) on intact mitochondria and cells: STC-1 uncouples oxidative phosphorylation and its actions are modulated by nucleotide triphosphates. Mol. Cell. Endocrinol. 264:90-101.

Brown, J.C.L., A.R. Gerson, J.F. Staples. 2007. Mitochondrial metabolism during daily torpor in the dwarf Siberian hamster: the role of active regulated changes and passive thermal effects. Am. J. Physiol. 293:R1833-1845.

Muleme, H. M, Walpole, A. C. and Staples, J. F. 2006. Mitochondrial metabolism in hibernation: Metabolic suppression, temperature effects and substrate preferences. Physiol. Biochem. Zool. 79(3): 474-483.

West, T.G., Donohoe, P.H., Staples, J.F. and Askew, G.N. 2006. The role of skeletal muscle in the hypoxia induced responses of submerged frogs., J. Exp. Biol. 209:1159-1168.

Schaefer, C. D. and Staples, J. F. 2006. Mitochondrial metabolism in mammalian cold acclimation: magnitude and mechanisms of fatty acid induced uncoupling. J. Therm. Biol. 31(4):355-361.

Staples, J. F., Koen, E.L. and Laverty, T.L. 2004. “Futile cycle” enzymes in the flight muscles of North American bumblebees. J. Exp. Biol. 207(5): 749-754.

Staples, J. F., Webber, D. M. and Boutilier, R. G. 2003. Environmental hypoxia does not constrain the diurnal depth distribution of free-swimming Nautilus pompilius. Physiol. Biochem. Zool. 76(5):644-651.

Staples, J. F., Hershkowitz, J. J. and Boutilier, R. G. (2000). Effects of ambient PO2 and temperature on oxygen uptake in Nautilus pompilius. J. Comp. Physiol. B. 170(3):231-236.

Suarez, R. K., Staples, J. F., Lighton, J. R. B. and Mathieu-Costello, O (2000). Mitochondrial function in flying honeybees (Apis mellifera): respiratory chain enzymes and electron flow from complex III to oxygen. J. Exp. Biol. 203:905-911.

Suarez, R. K., Staples, J. F. and Lighton, J. R. B. (1999). Turnover rate of mitochondrial respiratory chain enzymes in flying honeybees (Apis mellifera). J. Exp. Zool. 284(1):1-6.

Staples, J. F. and Hochachka, P. W. (1998). The effect of hibernation status and cold-acclimation on hepatocyte gluconeogenesis in the golden-mantled ground squirrel (Spermophilus lateralis). Can. J. Zool. 76(9):1734-1740.

Hochachka, P. W., McClelland, G.B., Burness, G.P., Staples, J.F. and Suarez, R.K. (1998) Integrating metabolic pathway fluxes with gene-to-enzyme expression rates. Comp. Biochem. Physiol. B. 120(1):17-26.

Staples, J. F. and Suarez, R. K. (1997). Honeybee flight muscle phosphoglucose isomerase: Matching enzyme capacities to flux requirements at a near-equilibrium reaction. J. Exp. Biol. 200:1247-1254.
Staples, J. F. and Hochachka, P. W. (1997). Liver energy metabolism during hibernation in the golden-mantled ground squirrel, Spermophilus lateralis. Can. J. Zool. 74(7):1059-1065.

Suarez, R. K., Staples, J. F., Lighton, J. R. B. and West, T. G. (1997). Relationships between enzymatic flux capacities and metabolic flux rates: Nonequilibrium reactions in muscle glycolysis. Proc. Natl. Acad. Sci. 94:7065-7069.

This page was last updated on October 30, 2012
Biology Web Contact: vlightft@uwo.ca