Dr. Brenda Murphy
Clinical Human Cytogenetics & Molecular Genetics
Murphy BC, O’Reilly RL and Singh SM.DNA methylation and mRNA expression of SYN IIIa,a candidategene for schizophrenia. BMC Medical Genetics (2008) 9:115.
Murphy BC, Scriver C R and Singh SM. CpG methylation accounts for a recurrent mutation (c.1222C>T) in the human PAH gene. Human Mutat (2006) 27:975.
Murphy BC, O’Reilly R and Singh SM. Site-specific cytosine methylation in S-COMT promoter in 31 brain regions with implications for studies involving schizophrenia. AJMG Part B (Neuropsychiatric Gen) (2005) 133B:37-42.
Singh SM, McDonald P, Murphy BC and O’Reilly R. Incidental neurodevelopmental episodes in the etiology of schizophrenia: an expanded developmental model. Clin Genet (2004) 65:435-440.
Singh SM, Murphy BC and O’Reilly R. Involvement of gene-diet/drug interaction in DNA methylation and its contribution to complex diseases: from cancer to schizophrenia. Clin Genet (2003) 64:451-460.
Lewis MJ, McDonald P, Murphy BC, O’Reilly R. and Singh SM. Appraisal of genetic and epigenetic congruity of a monozygotic twin pair discordant for schizophrenia. J Med Genet (2002) 39:1-6.
Murphy BC , Chiu T, Harrison M, Uddin RK and Singh SM. Examination of ethanol responsive liver and brain specific gene expression, in mouse strains with variable ethanol preferences, using cDNA expression arrays. Biochem Genet (2002) Dec 40(11-12):395-410.
Singh SM, Murphy BC and O’Reilly R. Monozygotic twins with chromosome 22q11 deletion and discordant phenotypes: update with an epigenetic hypothesis. J Med Genet (2002) Nov 39(11):e11.
Singh SM, Murphy BC and O’Reilly R. Epigenetic contributors to the discordance of monozygotic twins. Clin Genet (2002) Aug 62(2):97-103.
Ainsworth PJ, Bolton CF, Murphy BC, Stuart JA, Hahn AF. Genotype/phenotype correlation in affected individuals of a family with a deletion of the entire coding sequence of the connexin 32 gene. Hum Genet (1998) Aug; 103:242-244.
Murphy BC , O’Reilly R and Singh SM. Epigenetic implications in schizophrenia: site-specific cytosine Methylation in S-COMT promoter on 22q11. Am J Hum Gen (2004) Oct:A
Murphy BC , O’Reilly R. and Singh SM. Methylation and Val/Met polymorphism of COMT gene in patients with schizophrenia. World Congress Psychiatric Genetics 2004 Abstract.
Murphy BC , O’Reilly R and Singh SM. Testing two hit hypothesis for schizophrenia using 22q11 deleted patients with psychiatric disorders. Psy Genomics Conference 2003 Abstract.
Murphy BC , Harrison ML, Uddin RK, Chiu T and Singh SM. Expression array profile based identification of candidate genes for complex response phenotypes with specific reference to alcohol. Am J Hum Gen (2000) Oct 67(4):A1893.
Black AK , Laansoo PA, Schisler NJ, Murphy BC and Singh, SM. Regulatory Features of the Cas-1 genomic organization and evolution associated with oxygen radical metabolism, health and disease. Am J Hum Gen (2000) Oct 67(4):A956.
Deb-Rinker P, O’Reilly RL, Murphy BC and Singh SM. Importance of differential methylation of a 12q13 specific RDA-derived retroviral related sequence (gb AF135486) in schizophrenia. Am J Hum Gen (2000) Oct 67(4):A1883.
Murphy BC , Chiu T, McDonald P, Singh SM. Ethanol responsive genes contributing to alcoholism identified by cDNA expression arrays. Am J Hum Gen (1999) Oct 65(4):A463.
Harrison ML, Uddin KR, Treadwell J, Murphy BC, Singh SM. mRNA differential display identifies novel strain specific ethanol responsive (SSER) cDNAs involved in alcohol preference. Am J Hum Gen (1999) Oct 65(4):A273.
Chiu T, Harrison M, Murphy BC, Uddin KR, Singh SM. Strain-specific ethanol-response (SSER) cDNAs identified by differential display: A novel strategy to elucidate the complex etiology of alcohol responses/effects. Am J Hum Gen (1998) Oct 63(4):A323.
Ainsworth PJ, Murphy BC, Tan CC, Hahn AF. Genotype/phenotype correlation in affected individuals of a family with a deletion of the entire coding sequence of the connexin 32 gene. Am J Hum Gen (1997) Oct 61(4):A325.
Murphy BC, Tan CC, Ainsworth PJ, Hahn AF. Molecular studies on a family with a deletion of the entire coding sequence of the connexin 32 gene. The Canadian Society of Genetics Conference. Abstract & Poster
UNIVERSITY OF WESTERN ONTARIO DEPARMENT OF IMMUNOLOGY. July 2010. Antibody Diversity
CREDIT VALLEY HOSPITAL DEPARTMENT OF GENETICS. May 2008. Identifying Genetic Risks in Common Multi-factorial Disorders: Schizophrenia & Chromosome 22
CREDIT VALLEY HOSPITAL DEPARTMENT OF GENETICS. Feb 2007. Familial Breast Cancer Testing in Ontario
MCMASTER UNIVERSITY DEPARTMENT OF GENETICS. Dec 2006. Familial Adenomatous Polyposis & Hereditary Nonpolyposis Colon Cancer
MCMASTER UNIVERSITY DEPARTMENT OF GENETICS. Nov 2006. Familial Breast Cancer
MCMASTER UNIVERSITY DEPARTMENT OF GENETICS. Oct 2006. Cystic Fibrosis: Most common fatal autosomal recessive disease in humans
Department of Psychiatry; Academic Research Day in London. June 2005. Screening For Genetic & Epigenetic Alterations In Schizophrenia Candidate Genes Located on Chromosome 22q
ASSOCIATION OF GENETIC COUNSELLORS OF ONTARIO in Ottawa. 1996. LaRoche Cystic Fibrosis Multiplex Kit (first clinical trials in Ontario)
Member #08647 COLLEGE OF MEDICAL LABORATORY TECHNOLOGISTS OF ONTARIO ( CMLTO). 1985 to present. Registered in Cytogenetics and Molecular Genetics
Member #0985 ASSOCIATION OF CYTOGENETIC TECHNOLOGISTS. 1992-93.
Member #999999956 NATIONAL CERTIFICATION AGENCY (NCA). 1992-93. Registered in Cytogenetics
Member #32313 ONTARIO SOCIETY OF MEDICAL TECHNOLOGY ( OSMT) 1985 to present
Member #32313 CANADIAN SOCIETY OF MEDICAL LABORATORY SCIENCE ( CSMLS). 1985 to present. FORMERLY THE CANADIAN SOCIETY OF LABORATORY TECHNOLOGY (CSLT)
CCMG Post-Doctoral Fellowship. Canadian College of Medical Genetics Post-doctoral Fellowship MOLECULAR GENETICS FUNDED BY THE MINISTRY OF HEALTH. McMaster Health Sciences ( Hamilton) Department of Pathology & Molecular Medicine 2006-2008
Excellence in Undergraduate Teaching UWO, London. Nominated for my teaching of Biology 3592A “Principles in Human Genetics” 2006
Angela Armitt Teaching Award UWO, London. Nominated for my accumulated teaching activities at UWO 2005-2006
Excellence in Undergraduate Teaching UWO, London. Nominated by my students for my teaching of Biology 4560B “Human Molecular Genetics” 2004-2005
Special University Scholarship UWO, London. Full-time students maintaining an “A” average 2002 to 2004
Graduate Teaching Award UWO, London. Nominated for my teaching involvement with Biology 3592A “Principles in Human Genetics” 2002, 2006
Certificate of Achievement UWO, London. Singularly identified for outstanding participation in the radiation protection program 2002
International Founder’s Fund CSMLS, Hamilton. 2001 recipient; funds used to attend the American Society of Human Genetics Meeting in San Diego, California 2001
CSLT Continuing Education CSLT, Hamilton. Accumulation of 30 CE Credits in 4 years 1990
Ontario Scholarship Award PROVINCE OF ONTARIO. Honours standing in grade 13 1981
A.B. Lucas Silver Award A.B. LUCAS SECONDARY SCHOOL, London. Outstanding achievements in academics and sports while at A.B. Lucas High School 1981
Dr Ames Math Award GLENDALE JUNIOR HIGH SCHOOL, Hamilton. Highest math mark 1976
Principal's Award GLENDALE JUNIOR HIGH SCHOOL, Hamilton. Highest academic mark 1976
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July 12, 2010
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