Dr. Murphy's links: Dr. Brenda Murphy
Clinical Human Cytogenetics & Molecular Genetics
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Position: Assistant Professor Office: B&G Rm 3034 Office Phone: 519-661-2111 x86501 Fax: 519-661-3935 Email: bcmurphy@uwo.ca |
1. Undergraduate Teaching:
I have been teaching undergraduate Biology and Genetics courses at Western since 1992. This is an ideal position for me as I am very committed to life long learning and am known to always have an interesting genetic article in my hand to chat about. I thoroughly enjoy my daily interactions with faculty, sfaff and students, especially those eager to share ideas on human genetic topics. While at Western, I have taught the following undergraduate courses: General Biology (Biology 1202B), Genetics in Everyday Life (Biology 2001B), Principles in Human Genetics (Biology 3592A), Genone and Beyond: A Laboratory Course (Biology 3596A), Human Molecular Genetics (Biology 4560B), Genes & Genomes I (Biology 4561A), Genes & Genomes II (Biology 4562B), Investigative Tools in Genetics (Biology 4582), Co-technical Supervisor for Undergraduate Independent Research Projects (Biology 4999E).
2. Research:
My research interest lies in the cytogenetic, molecular genetic and biochemical genetic diagnosis of human genetic diseases. I am especially interested in genotype/epigenotype-phenotype correlations for clinical diagnostic purposes. At the beginning of my genetic career I worked at the local hospital in both the Cytogenetic and the Molecular Diagnositic laboratories for ~15 years. When I moved to Western I expanded upon this knowledge by studying genetically identical twins discordant for disorders that are genetically more complex and have an interaction with environmental factors. In addition, I am interested in chimpanzee comparative genomics, schizophrenia, cancer (breast cancer, colon cancer and leukemia), epigenomics, imprinting, pharmacogenomics, immunogenomics, human development, teratogenes, nurigenomics, genome structure (telomeres, subtelomeres, centromeres, low copy repeats, copy number variation, chromosome breakpoints, unbalanced chromosome rearrangements), microarray meta-analysis, comparative genomic hybridizaton assays , next generation sequencing techniques and bioinformatics.
Human Genetic Training:
- CCMG Molecular Genetic Postdoctoral Fellowship training at McMaster University in Hamilton, Ontario and Credit Valley Hospital in Mississauga, Ontario Canada
- PhD Biology from The University of Western Ontario in London, Ontario, Canada
- Human Molecular Genetics Diploma from the Michener Institute of Applied Health Science in Toronto, Ontario Canada
- Human Cytogenetics Diploma from the Micherner Institute of Applied Health Science in Toronto, Ontario Canada
- BSc Biology from The University of Western Ontario in London, Ontario Canada
Professional Experience & Memberships:
- Previous Clinical Genetic Examination Coordinator for The Canadian Society of Medical Laboratory Science (CSMLS)
- Clinical Registered in Clinical Cytogenetics and Molecular Genetics with The Canadian Medical Laboratory Technologists of Ontario (CMLTO)
- Member of The Canadian Society of Medical Laboratory Science (CSMLS)
- Member of The Ontario Society of Medical Technologists (OSMT)
