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Dr. Priti Krishna
Protein Folding / Hormone Regulation / Functional Genomics
Teaching
Undergraduate:
Biol 397b (Regulation of Gene Expression)
This course covers mechanisms of transcription and the principles of transcriptional regulation in both prokaryotes and eukaryotes. The course content includes discussion of DNA biochemistry/structure and topology; bacterial and eukaryotic chromosome structure; topoisomerases, and the relationship of all the above with transcription; discussion of bacterial RNA polymerase, the concept of operon, regulatory circuits, phage strategies (lambda to demonstrate layers of regulation); termination of transcription, antitermination and attenuation; eukaryotic RNA polymerases, promoters, enhancers, transcription factors (transcriptional activators, co-activators, repressors, how signals control transcriptional regulators); motifs and domains of transcriptional factors involved in protein:DNA and protein:protein interactions; controlling chromatin structure at transcription by histone modifications and chromatin remodeling; DNA methylation; gene silencing, and the role of RNAs in gene regulation.
Biol 493 (Seminar in Genetics)
The primary focus of this course is to offer skills necessary to search, understand, present (written and oral) and discuss published literature on recent topics in genetics. The course includes lectures, invited research seminars, student seminars, term papers, and poster presentation.
Graduate:
Biol. 604a (Topics in Hormone Signaling)
Hormonal signaling plays a pivotal role in almost every aspect of plant development and plant responses to environmental conditions. The systematic application of genetic and molecular techniques has led to key insights that have revitalized the field. The focus here is to familiarize students with up-to-date research, approaches and technologies in this area that will facilitate their own research projects.
