DR. KATHLEEN HILL
Graduate and Undergraduate
Genome organization and integrity
There are multiple research projects available for student research in my laboratory. My research examines the relationship between the amount and type of DNA damage occurring with development and aging. We measure mutation load following environmental exposures to DNA damaging agents. We examine the relationship between mutation load and predisposition to aging-associa ted diseases such as cancer and neurodegeneration. We use transgenic mouse mutation detection systems to identify and describe different types of DNA damage. These mice contain a bacterial gene that can be retrieved from mouse tissues and examined for DNA damage that occurred in the mouse. We will also be exploring the development of new mutation detection systems.
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April 8, 2010
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