Undergraduate Course 4451F Online

 

1. Course Information

Course number:
ACB 4451F, Section 650, Fall 2013

Course Name:
Integrative Neuroscience - Online

Course Director:
Dr. Susanne Schmid

Office: MSB 470, Medical Sciences Building
Phone: (519) 661-2111, ext. 82668
Email: Susanne.schmid@schulich.uwo.ca

Prerequisite: Physiol. 3120, or 3140 (can be waived by course co-ordinator)

Course description:
This course examines brain functions underlying specific fundamental behavioural tasks. Topics
include learning and memory, reward and addiction, neurodevelopment and regeneration, cognitive function and aging, and mental disorders. The course emphasizes the integrative understanding of the connection between molecular/cellular processes and behaviour.

Apart from the neurobiological content the course will encourage active participation. Students will be exposed to labs, reading original research articles, and presenting neurobiological topics. The first part of the course will briefly repeat some basics of neuroscience and will focus on consolidation of this knowledge by applying it during the labs. The lectures will be interactive and have the goal to bring all students to a similar high level of understanding the cellular principles underlying neuronal function.

This first part will also focus on specific skills, such as designing and documenting an experiment, writing a protocol, using a brain atlas in order to identify brain structures, searching for literature in online databases, working in a team, etc.

The second part of the course will focus on different systems and the brain structures and mechanisms involved in these systems. Occasionally, specialists that do research here at UWO within the specific topics will give a guest lecture. This will provide a glimpse of the neuroscience research that is going on here at Western.
Marking will be based on lab exercises and assignments, and the final exam. In some weeks it will be necessary to read an article, gather material or prepare a written assignment additionally to the course hours. Additional reading about the course topics in a textbook is strongly encouraged, but it is not required for the final exam.  The final exam will be short answer/essay type questions, no multiple choice.

Time of Live Classrooms:  Mon and Wed, 11:30 -12:30

Participation in live classrooms is not mandatory, all lectures will be archived and can be revisited any time.

Books and Notes:

Course materials and textbook suggestions will be discussed during the first lecture. Lab materials and manuals will be provided before labs or made available through Owl.

Absence from course commitments

A. Absence for medical illness:
Students must familiarize themselves with the Policy on Accommodation for Medical Illness:
https://studentservices.uwo.ca/secure/index.cfm

Statement from the Dean’s Office
If you are unable to meet a course requirement due to illness or other serious circumstances, you must provide valid medical or other supporting documentation to the Dean's office as soon as possible and contact your instructor immediately.  It is the student's responsibility to make alternative arrangements with their instructor once the accommodation has been approved and the instructor has been informed. In the event of a missed final exam, a "Recommendation of Special Examination" form must be obtained from the Dean's Office immediately. For further information please see: http://www.uwo.ca/univsec/handbook/appeals/medical.pdf
A student requiring academic accommodation due to illness, should use the Student Medical Certificate when visiting an off-campus medical facility or request a Record's Release Form (located in the Dean's Office) for visits to Student Health Services.

The form can be found at: https://studentservices.uwo.ca/secure/medical_document.pdf

The Policy on Accommodation for Medical Illness is also available on the BMSUE secure site:
www.uwo.ca/bmsc

B. Absence for non-medical reasons:
If you are unable to meet a course requirement due to non-medical reasons documentation must be submitted by the student directly to the appropriate Faculty Dean`s Office and not to the instructor. It will subsequently be the Dean`s Office that will determine if accommodation is warranted.

C. Special Examinations
A Special Examination is any examination other than the regular examination, and it may be
offered only with the permission of the Dean of the Faculty in which the student is registered, in consultation with the instructor and Department Chair. Permission to write a Special Examination may be given on the basis of compassionate or medical grounds with appropriate supporting documents.
A Special Examination must be written at the University or an Affiliated University College no later than 30 days after the end of the examination period involved. To accommodate unusual circumstances, a date later than this may be arranged at the time permission is first given by the Dean of the Faculty. The Dean will consult with the instructor and Department Chair and, if a later date is arranged, will communicate this to Registrarial Services. If a student fails to write a scheduled Special Examination, permission to write another Special Examination will be granted only with the permission of the Dean in exceptional circumstances and with appropriate supporting documents. In such a case, the date of this Special Examination normally will be the scheduled date for the final exam the next time the course is offered.

5. Course Syllabus
The first part of the course will repeat some basics of neuroscience and will focus on consolidation of this knowledge by applying it during the labs. The lectures will be interactive and have the goal to bring all students to a similar level.

This first part will also focus on specific skills, such as designing and documenting an experiment, writing a protocol, using a brain atlas in order to identify brain structures, searching for literature in online databases, working in a team, etc.

The second part of the course will focus on different systems and the brain structures and mechanisms involved in these systems. It also provides a glimpse of the neuroscience research that is going on here at Western.

Evaluation:

Anatomy lab

Sept. 18

10%

Histology lab

Sept. 20

10%

Neurophysiology lab

Sept. 30

10%

Experiment design

Oct. 16

10%

Experiment protocol

Oct. 21

10%

Written paper critique

Nov. 19

20%

Final exam

TBA (Dec. 14-17)

30%


It is not mandatory to attend the live Wimba classroom, but it is strongly recommended. Labs need to be accomplished in the week indicated on the timetable. Please adhere to the deadlines for submitting lab assignments. Late submission will result in a 0% mark, unless course coordinator has been notified and permitted late submission before the deadline has passed.

Some assignments can be accomplished as group work (online or by meeting group members). Group work means that the product is generated through the intense interaction of two or three students. It is not acceptable that one student only revises the product of another student or that different students contribute different parts that are just appended. In case of a group submission, it is important to indicate all names of group members and the way the group worked together, so that the product is not identified as plagiarism. All group members should still submit the (identical) assignment through their Owl, so that it is not marked as missed assignment.

In some weeks it will be necessary to read an article, gather material or prepare a written assignment additionally to the course hours. Additional reading about the course topics in a textbook is strongly encouraged, but it is not required for the final exam.

Course outline Fall 2013 online course

Mon, Sept. 09
Wed, Sept. 11

No course
Introduction, Evolution of the Brain, Macroscopic structure
Lab: Neuroanatomy of the human CNS – assignment

Susanne Schmid
SS
SS

Mon, Sept. 16
Wed, Sept. 18

Neurons & Glia
Structure & Function
Lab: Histology – assignment

SS
SS
SS

Mon, Sept. 23
Wed, Sept. 25

Passive properties of the neuronal membrane 
Active propagation of signals
ComputerLab: Neurophysiology – assignment

SS
SS
SS

Mon, Sept. 30
Wed, Oct. 02

Synaptic transmission
Synaptic plasticity

SS
SS

Mon, Oct. 07   unit 1
Wed, Oct. 09

Intro: Synaptic plasticity and learning & memory
Research on learning & memory
How to design and protocol an experiment - Experiment
design assignment

SS
SS
SS

Mon, Oct. 14   
Wed, Oct. 16 
Fri, Oct. 18

Thanksgiving
Learning experiment: Protocol assignment
Student presentations on unit 1


SS
SS, students

Mon, Oct. 21    unit 2
Wed, Oct. 23  
Fri, Oct. 25

Intro: Neurodevelopment and Regeneration of Neurons
Research in Neural Regeneration
Student presentations on unit 2

SS
AB
SS, students

Mon, Oct. 28    unit 3
Wed, Oct. 30
Fri, Nov. 01

The brain immune system
Neuroinflammation & neurodegenerative diseases

SS
SW

Mon, Nov. 04   unit 4
Wed, Nov. 06
Fri, Nov. 08

Intro: Reward and Addiction
Research on Addiction
Student presentations on unit 4

SS
SL?
SS, students

Mon, Nov 11
Wed, Nov. 13
Fri, Nov. 15

(SFN)
(SFN)
Student presentations on unit 3



SS, students

Mon, Nov. 18    unit 5
Wed, Nov. 20
Fri, Nov. 22

Intro: Neuronal death and synapse elimination
Research on neurodegenerative diseases (Prion diseases)
Student presentations on unit 5

SS
MP
SS, students

Mon, Nov. 25    unit 6
Wed, Nov. 27
Fri, Nov. 29

Intro: Neuronal basis of movement control
Research on movement disorders (Parkinson’s Disease)
Student presentations on unit 6

SS
VP
SS, students

Mon, Dec. 2     unit 7
Wed, Dec. 4
Fri, Dec. 6

Intro: Cognitive function and aging
Research on mental disorders (Schizophrenia)
Student presentations on unit 7

SS
NR
SS, students

AB: Arthur Brown; MP: Marco Prado; NR: Nagalingam Rajakumar; VP: Vania Prado; SW: Shawn Whitehead

6. Additional Information/Statements

Statement on Use of Electronic Devices
All students need to have a computer with internet access, and a headset (or microphone and
speakers).

No electronic devices are to be used during the final exams.

Statement on Academic Offences
Scholastic offences are taken seriously and students are directed to read the appropriate policy,
specifically, the definition of what constitutes a Scholastic Offence, at the following Web site:
http://www.uwo.ca/univsec/handbook/appeals/scholoff.pdf

All required papers may be subject to submission for textual similarity review to the commercial plagiarism detection software under license to the University for the detection of plagiarism. All papers submitted for such checking will be included as source documents in the reference database for the purpose of detecting plagiarism of papers subsequently submitted to the system. Use of the service is subject to the licensing agreement, currently between The University of Western Ontario and Turnitin.com (http://www.turnitin.com ).

Computer-marked multiple-choice tests and/or exams may be subject to submission for similarity review by software that will check for unusual coincidences in answer patterns that may indicate cheating.

Support Services:

Registrarial Services (http://www.registrar.uwo.ca),
Student Development Services: http://westernusc.ca/services/
Students that are in emotional/mental distress should refer to Mental Health@Western
http://www.uwo.ca/uwocom/mentalhealth/ for a complete list of options about how to obtain help.
Academic Counselling (Science and Basic Medical Sciences):
http://www.uwo.ca/sci/counselling/index.html
Student Health Services:  http://www.shs.uwo.ca/