Undergraduate Course 4451A


Integrative Neuroscience


Course number: ACB 4451A Summer Distance 2011
Course title: Integrative Neuroscience

Course Director: Dr. Susanne Schmid
                             Office:MSB 470, Medical Sciences Building
                             Phone: (519) 661-2111, ext. 82668
                             Email: Susanne.schmid@schulich.uwo.ca

Prerequisite: Physiol. 3120, or 3140 (can be waived by course co-ordinator)

Course description:

This course will examine brain functions underlying specific fundamental behavioural tasks.
Topics include learning and memory, circadian rhythms, reward and addiction, and stress. It will
also give a short introduction into the neurobiology of neurological and neuropsychiatric
disorders. The course emphasizes the integrative understanding of the connection between
molecular/cellular processes and behaviour.
Apart from the neurobiological content the course will encourage active participation and
focuses on developing skills. Students will be exposed to labs, reading original research articles,
and scientific writing.
The first part of the course (grey in the following list) will repeat some basics of neuroscience
and will focus on consolidation of this knowledge by applying it during the online labs. The
lectures will be interactive and have the goal to bring all students to a similar level.
The labs will focus on specific skills training, such as designing and documenting an experiment,
writing a protocol, using a brain atlas in order to identify brain structures, writing a grant
application, working in a team, etc.
The second part of the course will focus on different systems and the brain structures and
mechanisms involved in these systems. It will provide a glimpse of the neuroscience research
that is going on here at Western.
Marking will be based on lab exercises and assignments, the final exam, and the active
participation in online classes and/or discussions.
In some weeks it will be necessary to read an article, gather material or prepare a written
assignment additionally to the course hours. Additional reading about the course topics in a
textbook is strongly encouraged, but it is not required for the final exam.
         

Time and Location:  Tues. and Wed, 10:00 a.m.
Office Hours: Wed. after class (11:00 a.m. - 12:30 p.m.)

Books and Notes:

Course materials and textbook suggestions will be discussed during the first lecture. Lab materials and manuals will be made available through WebCT/Wimba.

Evaluation:

Anatomy assessment online, submit by June 15 5%
Histology assignment online, submit by June 15 10%
Physiology assignment online, submit by June 15 10%
Experiment assignment online, submit by June 30 10%
Protocol assignment online, submit by June 30 10%
OGS Grant assignment online, submit by July 15 10%
Scientific article assignment online, submit by July 15 10%
Final exam TBA (July 25th - Aug. 3rd, 2011) 30%
Active participation 5%

It is not mandatory to attend the live Wimba classroom, but it is strongly recommended. Participation is marked according to online questions during live classes and participation at online discussion. Students are encouraged to log into the online platform at least 1-3 times per week. The course coordinator and teaching assistants will monitor online discussions on a daily basis. Labs should be accomplished in the week indicated on the timetable. Please adhere to the deadlines for emailing lab assignments. Late submission will result in a 0% mark, unless course coordinator has been notified and permitted late submission before the deadline has passed. Most assignments can be accomplished as group work (online or by meeting group members). In this case it is important to indicate all names of group members that contributed to an assignment, so that it is not identified as plagiarism. All group members should still submit the assignment through their WebCT, so that it is not marked as missed assignment.


Course outline (minor changes may still occur)

Mon, May 10
Wed, May11

Introduction, course overview, rules & remarks
Evolution of the Brain, Macroscopic structure
Lab: Neuroanatomy of the human CNS

Unit 1

Tues, May 17
Wed, May 18

Neurons & Glia          
Structure & Function
Lab: Histology

Unit 2

Tues, May 24
Wed, May 25

Neurophysiology I 
Neurophysiology II
Lab: Neurophysiology

Unit 3

Tues, May 31
Wed, June 1

(Canadian Neuroscience Meeting) 
(Canadian Neuroscience Meeting)

 

Tues, June 7
Wed, June 8
    

Synaptic transmission (CAN meeting)
Synaptic plasticity (CAN meeting)
Lab: experiment design

Unit 4

Tues, June 14
Wed, June 15

Synaptic plasticity and learning I
Synaptic plasticity and learning II
Lab: experiment protocol

Unit 5

Tues, June 21   
Wed, June 22   
    

Reward
Addiction

Unit 6

Tues, June 28  
Wed, June 29  

Neurodevelopment
Regeneration of Neurons
Lab: reading a scientific paper

Unit 7

Tues, July 5
Wed, July 6

Neuronal death and synapse elimination
Grad or Med school? - Let's talk about your future - Lab: reading a scientific paper

Unit 8

Tues, July 12
Wed, July 13

The Neuroendocrine System Overview
Circadian Rhythms

Unit 9

Tues, July 19  
Wed, July 20

Stress, Stress Disorders
Food Intake and Metabolism

Unit 10

Tues, July 26
Wed, July 27

Cognitive function & Aging
Neurodegenerative diseases

Unit 11

TBA (July 29- Aug 3)

Final Exam

 

 

 


university of western ontario department of anatomy and cell biology school of medicine