Research Interest:
Research encompasses 3 areas of Neuroscience. Firstly, the role of neuroinflammation in the combination of Alzheimer’s Disease
and the associated risk factors such as stroke, diabetes, hypertension and diabetes in animal models. Secondly, the use of
functional MRI of the human brain to examine the neural correlates of mental stress and cardiovascular reactivity. Finally,
the examination of the effect of novel agents to be used in the treatment of schizophrenia.
Director of a development project funded by the Canadian International development Agency which involves capacity building in
the nursing and medical schools in Rwanda
Selected Publications:
• Whitehead, S.N., Cheng, G., Hachinski, V.C. and Cechetto, D.F. (2007). Progression of neuroinflammation and cognitive deficits in
a rat model of Alzheimer's disease and cerebral ischemia. Stroke 38: 3245-3250.
• Whitehead, S.N., Bayona, N.A., Hachinski, V.C. and Cechetto, D.F. (2006) . Effects of triflusal and aspirin in a rat model of
cerebral ischemia. Stroke 38: 381-387.
• Cheng, G., Whitehead, S.N., Hachinski, V.C. and Cechetto, D.F. (2006) . Effects of pyrrolidine dithiocarbamate on beta-amyloid
toxicity in a rat model of Alzheimer’s Disease. Neurobiol. Of Dis. (In Press).
• Whitehead, S.N., Cheng, G., Hachinski, V.C., and Cechetto, D.F. (2005). Interaction between a rat model of
cerebral ischemia and beta-amyloid toxicity: II. Effects of triflusal. Stroke 36: 1782-1789.
• Whitehead, S.N., Cheng, G., Hachinski, V.C., and Cechetto, D. F. (2005) . Interaction between a rat model of
cerebral ischemia and beta-amyloid toxicity: I. inflammatory responses. Stroke 36: 107-112.
• Topolovec, J.C., Gati, J.S., Menon, R.s., Shoemaker, J.K. and Cechetto, D.F. (2004) . Human cardiovascular and gustatory brain
stem sites observed by functional magnetic resonance imaging.. J. Comp. Neurol. 471: 446-461.