Dr. Belliveau's research focuses on the role of gap junctions in the development and differentiation of the nervous system.
Specific areas include neurotrophic control of connexins via members of the neurotrophin family of growth factors and
glia-neuronal interactions and their connexin partners in the peripheral nervous system.
• Belliveu, D.J., Bani-Yagoub, M., McGirr, R.M.L., Naus, C.C.G., and Rushlow, W.R. (2006) Enhanced neurite outgrowth in PC12 cells mediated by connexin hemi-channels and ATP. J. Biol. Chem. 28: 20920-20931.
• Jimenez, T., Fox, W.P., Galipeau, J., Naus, C.C.G., Belliveau, D.J. (2006) Connexin overexpression differentially suppresses giloma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy. Cell Comm. & Adhes. 13:79-92.
• Cushing, P., Bhalla, R., Johnson, A.M., Rushlow, W.J., Meakin, S.O., and Belliveau, D.J. (2005) NGF effects connexin43 phosphorylation and gap junctional intercellular communication in connexin43 infected PC12 cells. J. Neurosci. Res. 82: 788-801.
• Rushlow, W.J., Seah, Y.H., Belliveau, D.J., Rajakumar, N. (2005) Changes in Calcineurin expression induced in the rat brain by the administration of antipsychotics. J. Neurochem. 94: 587-96.
• Qin, H., Shao, Q., Curtis, H., Galipeau, J., Belliveau, D.J., Wang, T., Alaoui-Jamali, M.A., and Laird, D.W.(2002) Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. J. Biol. Chem. 277: 29132-29138.
• Todo, T., Feigenbaum, F., Rabkin, S.D., Lakeman. F., Newsome, J.T., Johnson, P.A., Mitchell, E., Belliveau, D.J., Ostrove, J.M., and Martuza, R.L. (2000) Viral shedding and biodistribution of G207, a multimutated, conditionally-replicating Herpes Simplex Virus Type 1, after intracerebral inoculation in Aotus. Mol. Ther. 2: 588-595.