Research Interest:
Dr. Belliveau's research focuses on the role of gap junctions in the development and differentiation of the nervous system.
Specific areas include neurotrophic control of connexins via members of the neurotrophin family of growth factors and
glia-neuronal interactions and their connexin partners in the peripheral nervous system.
Selected Publications:
• Belliveu, D.J., Bani-Yagoub, M., McGirr, R.M.L., Naus, C.C.G., and Rushlow, W.R. (2006) Enhanced neurite outgrowth in PC12
cells mediated by connexin hemi-channels and ATP. J. Biol. Chem. 28: 20920-20931.
• Jimenez, T., Fox, W.P., Galipeau, J., Naus, C.C.G., Belliveau, D.J. (2006) Connexin overexpression differentially suppresses giloma
growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy. Cell Comm. & Adhes. 13:79-92.
• Cushing, P., Bhalla, R., Johnson, A.M., Rushlow, W.J., Meakin, S.O., and Belliveau, D.J. (2005) NGF effects connexin43
phosphorylation and gap junctional intercellular communication in connexin43 infected PC12 cells. J. Neurosci. Res. 82: 788-801.
• Rushlow, W.J., Seah, Y.H., Belliveau, D.J., Rajakumar, N. (2005) Changes in Calcineurin expression induced in the rat brain by the
administration of antipsychotics. J. Neurochem. 94: 587-96.
• Qin, H., Shao, Q., Curtis, H., Galipeau, J., Belliveau, D.J., Wang, T., Alaoui-Jamali, M.A., and Laird, D.W.(2002) Retroviral
delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant
gap junctional intercellular communication. J. Biol. Chem. 277: 29132-29138.
• Todo, T., Feigenbaum, F., Rabkin, S.D., Lakeman. F., Newsome, J.T., Johnson, P.A., Mitchell, E., Belliveau, D.J., Ostrove, J.M., and
Martuza, R.L. (2000) Viral shedding and biodistribution of G207, a multimutated, conditionally-replicating Herpes Simplex Virus
Type 1, after intracerebral inoculation in Aotus. Mol. Ther. 2: 588-595.